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  3. Rapilif-D 8/0.5 Capsule Combipack

Rapilif-D 8/0.5 Capsule Combipack, Pack of 10
Rapilif-D 8/0.5 Capsule Combipack, Pack of 10
Rapilif-D 8/0.5 Capsule Combipack, Pack of 10
Rapilif-D 8/0.5 Capsule Combipack, Pack of 10
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Composition :

DUTASTERIDE-0.5MG + SILODOSIN-8MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rapilif-D 8/0.5 Capsule Combipack

Rapilif-D 8/0.5 Capsule Combipack is used to treat benign prostatic hyperplasia (BPH) in adults. The prostate is a small, muscular gland in the male reproductive system. Benign prostatic hyperplasia is a common condition that occurs when the cells of the prostate gland begin to multiply.

Rapilif-D 8/0.5 Capsule Combipack is a combination of Silodosin and Dutasteride. This medicine works by blocking the action of alpha-1 receptors, causing smooth muscle relaxation in the bladder and prostate. Dutasteride blocks the action of a 5-alpha reductase enzyme, resulting in a shrinkage of the size of the prostate gland.

In some cases, you may experience certain common side effects such as dizziness, headache, nasal congestion (stuffy nose), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Take Rapilif-D 8/0.5 Capsule Combipack as advised. Your physician will decide the dosage based on your medical condition. You can take Rapilif-D 8/0.5 Capsule Combipack with or without food. It is advised not to take more than the recommended dose of Rapilif-D 8/0.5 Capsule Combipack. Do not chew, crush, or break the medicine. It is crucial to have your lipid profile checked regularly.

Inform your physician if you are allergic to Rapilif-D 8/0.5 Capsule Combipack. Avoid consumption of alcohol as it may increase the side effects like dizziness and low blood pressure. If you take Rapilif-D 8/0.5 Capsule Combipack with any antihypertensive medicine, your blood pressure could suddenly drop to a life-threatening level. So, avoid intake of Rapilif-D 8/0.5 Capsule Combipack with antihypertensive drugs. Rapilif-D 8/0.5 Capsule Combipack is not recommended for use in female population and children.

Uses of Rapilif-D 8/0.5 Capsule Combipack

Rapilif-D 8/0.5 Capsule Combipack is used in the treatment of Benign Prostatic Hyperplasia (BPH) in men. The detailed uses of Rapilif-D 8/0.5 Capsule Combipack are as follows:<br/>• Treatment of Benign Prostatic Hyperplasia (BPH): Rapilif-D 8/0.5 Capsule Combipack helps reduce prostate size by blocking the production of hormones responsible for its growth and also improves urinary flow and reduces symptoms like difficulty urinating, frequent urges, and weak urine stream.<br/>• Relaxation of Bladder and Prostate Muscles: Rapilif-D 8/0.5 Capsule Combipack works by relaxing the muscles in the bladder and prostate, making urination easier and helps relieve urinary discomfort associated with an enlarged prostate.<br/>• Prevention of Urinary Blockage: Rapilif-D 8/0.5 Capsule Combipack reduces the risk of complete urinary obstruction, which can occur if BPH is left untreated and helps maintain normal urinary function over time.<br/>

Directions for Use

• Rapilif-D 8/0.5 Capsule Combipack can be taken with or without food, as advised by your doctor • Follow your doctor's instructions on the dosage and timing of this medication. • Swallow Rapilif-D 8/0.5 Capsule Combipack as a whole with a glass of water. • Do not crush, chew, or open it.

Medicinal Benefits

  • Rapilif-D 8/0.5 Capsule Combipack is a combination of Silodosin and Dutasteride used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland.
  • Rapilif-D 8/0.5 Capsule Combipack causes smooth muscle relaxation in the bladder and prostate, and also causes a shrinkage of the size of the prostate gland.
  • It helps to relieve symptoms such as difficulty urinating or the urge to urinate more often and improve your ability to urinate. 

How Rapilif-D 8/0.5 Capsule Combipack Works

Rapilif-D 8/0.5 Capsule Combipack is a combination of two drugs, namely; Silodosin and Dutasteride. Silodosin works by blocking the action of alpha-1 receptors, causing smooth muscle relaxation in the bladder and prostate. Dutasteride works by blocking the action of a 5-alpha reductase enzyme, resulting in a shrink of the size of the prostate gland. Rapilif-D 8/0.5 Capsule Combipack reduces the BPH symptoms and improves your ability to urinate.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Rapilif-D 8/0.5 Capsule Combipack

Do not take more than the prescribed dose of Rapilif-D 8/0.5 Capsule Combipack as it may cause overdose. Symptoms of overdose include dizziness, drowsiness, fainting, or severe decrease in blood pressure. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Rapilif-D 8/0.5 Capsule Combipack if you are allergic to Rapilif-D 8/0.5 Capsule Combipack or any other components present in it. To treat your condition effectively, continue taking Rapilif-D 8/0.5 Capsule Combipack for as long as your doctor has prescribed it. Try not to stop taking it on your own.
  • If you take Rapilif-D 8/0.5 Capsule Combipack with any antihypertensive medicine, your blood pressure could suddenly drop to a life-threatening level. So, avoid intake of Rapilif-D 8/0.5 Capsule Combipack with antihypertensive drugs.
  • Inform your doctor if you have/had a heart attack or stroke or heart failure, low blood pressure, kidney or liver disease, have certain eye diseases, loss of vision due to loss of blood flow to the optic (eye) nerve before taking Rapilif-D 8/0.5 Capsule Combipack.
  • You are advised not to drive or operate heavy machinery after taking Rapilif-D 8/0.5 Capsule Combipack as it may cause dizziness.
  • Avoid consuming alcohol along with Rapilif-D 8/0.5 Capsule Combipack as it could lead to increased dizziness and drowsiness.
  • Older patients may be more sensitive to the side effects of Rapilif-D 8/0.5 Capsule Combipack, especially dizziness and low blood pressure when getting up from a sitting or lying position. 
  • Rapilif-D 8/0.5 Capsule Combipack is intended for male patients only. Therefore, it should not be administered to women and children under 18 years of age.

Drug-Drug Interactions

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SilodosinRitonavir
Critical
SilodosinTelaprevir
Critical

Drug-Drug Interactions

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SilodosinRitonavir
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Coadministration of Rapilif-D 8/0.5 Capsule Combipack with Ritonavir can significantly increase the blood levels and effects of Rapilif-D 8/0.5 Capsule Combipack, and this may cause low blood pressure and increase heart rate, especially when you rise from a sitting or lying position.

How to manage the interaction:
Taking Ritonavir and Rapilif-D 8/0.5 Capsule Combipack together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
SilodosinTelaprevir
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Co-administration of Telaprevir and Rapilif-D 8/0.5 Capsule Combipack together can increase the effect of Rapilif-D 8/0.5 Capsule Combipack which may lead to side effects like extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Telaprevir and Rapilif-D 8/0.5 Capsule Combipack together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
SilodosinCobicistat
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Co-administration of Cobicistat and Rapilif-D 8/0.5 Capsule Combipack together can increase the effect of Rapilif-D 8/0.5 Capsule Combipack which may lead to side effects including extremely low blood pressure, increased heart rate.

How to manage the interaction:
Taking Cobicistat with Rapilif-D 8/0.5 Capsule Combipack together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
SilodosinIndinavir
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Coadministration of Rapilif-D 8/0.5 Capsule Combipack with Indinavir may significantly increase the blood levels and effects of Rapilif-D 8/0.5 Capsule Combipack, this may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Taking Rapilif-D 8/0.5 Capsule Combipack with Indinavir together is not recommended s it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
SilodosinVoriconazole
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Co-administration of Rapilif-D 8/0.5 Capsule Combipack together with Voriconazole, may significantly increase the blood levels and effects of Rapilif-D 8/0.5 Capsule Combipack which may lead to side effects.

How to manage the interaction:
Taking Voriconazole and Rapilif-D 8/0.5 Capsule Combipack is not recommended, but it can be taken if prescribed by a doctor. If you experience dizziness, headache, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
SilodosinClarithromycin
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Taking Rapilif-D 8/0.5 Capsule Combipack with Clarithromycin may significantly increase the blood levels and effects of Rapilif-D 8/0.5 Capsule Combipack, this may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Co-administration of Clarithromycin and Rapilif-D 8/0.5 Capsule Combipack is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not stop using any medications without a doctor's advice.
SilodosinFosamprenavir
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Co-administration of Fosamprenavir and Rapilif-D 8/0.5 Capsule Combipack together can increase the effect of Rapilif-D 8/0.5 Capsule Combipack which may lead to side effects including extremely low blood pressure, increased heart rate.

How to manage the interaction:
Taking Fosamprenavir with Rapilif-D 8/0.5 Capsule Combipack together i not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
SilodosinDelavirdine
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Co-administration of Delavirdine and Rapilif-D 8/0.5 Capsule Combipack together can increase the effect of Rapilif-D 8/0.5 Capsule Combipack which may lead to side effects including extremely low blood pressure, increased heart rate.

How to manage the interaction:
Taking Rapilif-D 8/0.5 Capsule Combipack with Delavirdine together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
SilodosinItraconazole
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Coadministration of Itraconazole with Rapilif-D 8/0.5 Capsule Combipack can increase the blood levels and effects of Rapilif-D 8/0.5 Capsule Combipack, which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Itraconazole with Rapilif-D 8/0.5 Capsule Combipack together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
SilodosinSaquinavir
Critical
How does the drug interact with Rapilif-D 8/0.5 Capsule Combipack:
Coadministration of Saquinavir and Rapilif-D 8/0.5 Capsule Combipack may increase the effects of Rapilif-D 8/0.5 Capsule Combipack which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Saquinavir with Rapilif-D 8/0.5 Capsule Combipack together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However consult the doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, priapism (prolonged and painful erection unrelated to sexual activity) may also increase, nasal congestion, heart palpitation. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintaining a healthy weight, eating a balanced diet, and regular exercising may help your bladder empty at a normal rate.
  • Avoid consumption of alcohol to treat your condition effectively as consuming an excessive amount of alcohol may make you pee more and can irritate your bladder.
  • Limit the amount of fluids and caffeine you drink, especially before you go out or go to bed.
  • Stay warm, cold can make it feel more urgent to pee.
  • Avoid usage of tobacco.
  • Do daily exercise to strengthen your pelvic floor muscles.

Habit Forming

No

Therapeutic Class

GENITOURINARY TRACT AGENTS

Rapilif-D 8/0.5 Capsule Combipack Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

You are advised not to consume alcohol while taking Rapilif-D 8/0.5 Capsule Combipack as it makes you pee more and can irritate your bladder and also increased dizziness and lower blood pressure.

bannner image

Pregnancy

Not applicable

Women should not use Rapilif-D 8/0.5 Capsule Combipack as it is used to treat benign prostatic hyperplasia (BPH) in men only.

bannner image

Breast Feeding

Not applicable

Women should not use Rapilif-D 8/0.5 Capsule Combipack as it is used to treat benign prostatic hyperplasia (BPH) in men only.

bannner image

Driving

Unsafe

Rapilif-D 8/0.5 Capsule Combipack may cause dizziness. Therefore you are advised to drive and operate machinery only if you are alert.

bannner image

Liver

Caution

Rapilif-D 8/0.5 Capsule Combipack should be used with caution in patients with liver disease. The dose adjustment may be needed in such patients.

bannner image

Kidney

Caution

Rapilif-D 8/0.5 Capsule Combipack should be used with caution in patients with kidney disease. The dose adjustment may be needed in such patients.

bannner image

Children

Unsafe

Rapilif-D 8/0.5 Capsule Combipack is not recommended for children below 18 years of age as the safety and efficacy are not established.

Have a query?

FAQs

Rapilif-D 8/0.5 Capsule Combipack is used to treat the symptoms of Benign Prostatic Hyperplasia (BPH) in men.

No, Rapilif-D 8/0.5 Capsule Combipack should not be taken along with blood-pressure-lowering medicines. Rapilif-D 8/0.5 Capsule Combipack may cause a sudden drop in your blood pressure which could lead to dizziness or fainting. Therefore, if Rapilif-D 8/0.5 Capsule Combipack is taken along with blood pressure lowering medicines, it could lead to a severe decrease in blood pressure which could be lethal.

Yes, Rapilif-D 8/0.5 Capsule Combipack may cause dizziness. You are advised not to drive or operate heavy machinery after taking Rapilif-D 8/0.5 Capsule Combipack as it may cause dizziness. Drive or operate machinery only if you are alert.

No, Rapilif-D 8/0.5 Capsule Combipack should not be taken by women. It is intended to treat symptoms of benign prostatic hyperplasia (BPH) in adult men only.

No, you are advised not to consume alcohol while taking Rapilif-D 8/0.5 Capsule Combipack as it makes you pee more and can irritate your bladder and also increase dizziness and lower blood pressure. Therefore, you are advised not to consume excessive amounts of alcohol while taking Rapilif-D 8/0.5 Capsule Combipack.

Rapilif-D 8/0.5 Capsule Combipack is a combination of two drugs, namely; Silodosin and Dutasteride used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. Silodosin belongs to a class of alpha-1 receptors (located in prostate and bladder) blocker that works by blocking the action of alpha-1 receptors and causes smooth muscle relaxation in the bladder and prostate. Dutasteride belongs to a class of 5-alpha reductase that works by blocking the action of a 5-alpha reductase enzyme, resulting in a shrink of the size of the prostate gland. Rapilif-D 8/0.5 Capsule Combipack reduces the BPH symptoms and improves your ability to urinate.

The side effects of Rapilif-D 8/0.5 Capsule Combipack include dizziness, headache, diarrhoea, nasal congestion (stuffy nose), impotence (erectile dysfunction) and ejaculation disorder. If these side effects persist or worsen, please consult your doctor.

You should take Rapilif-D 8/0.5 Capsule Combipack for as long as it is prescribed by your doctor. It is usually advised for long term use. If you discontinue Rapilif-D 8/0.5 Capsule Combipack in the midway, it may worsen your condition.

Take Rapilif-D 8/0.5 Capsule Combipack as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it. Take it at the same time every day. Do not miss doses or stop the treatment before the prescribed duration, even if you feel well.

Rapilif-D 8/0.5 Capsule Combipack is effective if used in the dose and duration prescribed by your doctor. Even if you see improvement in your condition, do not stop using Rapilif-D 8/0.5 Capsule Combipack too early as the symptoms may return or worsen.

Benign prostatic hyperplasia (BPH) also known as prostate gland enlargement is a common condition in older men. The symptoms include urgent or frequent need to urinate, inability to completely empty the bladder and increased frequency of urination at night (nocturia).

The use of Rapilif-D 8/0.5 Capsule Combipack is contraindicated in patients who are allergic to any ingredients of it. Rapilif-D 8/0.5 Capsule Combipack should be used with caution in patients with underlying liver or kidney disease. If you have any concerns, consult your doctor.

Store Rapilif-D 8/0.5 Capsule Combipack in a cool, dry and dark place. Keep it out of reach of children.

Rapilif-D 8/0.5 Capsule Combipack is safe if used in the dose and duration prescribed by your doctor. Take it exactly as advised and do not miss any dose. Follow your doctor's instructions carefully and if any of the side effects bother you, inform your doctor.

It is best to take Rapilif-D 8/0.5 Capsule Combipack after meals. Swallow it as whole with water. Do not open, chew or crush it. Follow your doctor’s instructions carefully.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - RAP0109

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:38 AM IST

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Reference

  1. https://www.ciplamed.com/content/silofast-d-capsules

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