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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
R-Cinex 600 Tablet is used to treat and prevent tuberculosis. It contains Rifampicin, and Isoniazid, which works by killing the bacteria causing TB (tuberculosis). In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About R-Cinex 600 Tablet

R-Cinex 600 Tablet is used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.

R-Cinex 600 Tablet is a combination of two anti-tuberculosis drugs Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, R-Cinex 600 Tablet kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking R-Cinex 600 Tablet if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking R-Cinex 600 Tablet as it passes into breast milk. R-Cinex 600 Tablet may cause dizziness, and vision problems, so drive only if you are alert. Avoid alcohol consumption while taking R-Cinex 600 Tablet as it could lead to increased drowsiness, dizziness and liver damage.

Uses of R-Cinex 600 Tablet

R-Cinex 600 Tablet is used in the treatment of tuberculosis (TB). The detailed uses of R-Cinex 600 Tablet are as follows:

  • Treats active tuberculosis: R-Cinex 600 Tablet works by killing the bacteria that cause TB, helping to clear the infection from the lungs and other affected organs.
  • Prevents spread and recurrence: R-Cinex 600 Tablet is also used to prevent TB from coming back or spreading to others, especially in people at high risk.

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Directions for Use

  • R-Cinex 600 Tablet should be taken on an empty stomach, at least 30 minutes before or 2 hours after a meal.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow R-Cinex 600 Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

Key Benefits

R-Cinex 600 Tablet is a combination of two anti-tuberculosis drugs, Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, R-Cinex 600 Tablet kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

How R-Cinex 600 Tablet Works

R-Cinex 600 Tablet is a combination of two anti-tuberculosis drugs Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, R-Cinex 600 Tablet kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

Storage

Store in a cool and dry place away from sunlight
Side effects of R-Cinex 600 Tablet
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of R-Cinex 600 Tablet

Do not take more than the prescribed dose of R-Cinex 600 Tablet as it may cause overdose. The symptoms of overdose include stomach pain, nausea, vomiting, headache, itching, tiredness, dizziness, lightheadedness, drowsiness, fainting, blurred vision, or hallucinations. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take R-Cinex 600 Tablet if you are allergic to any of its contents; if you have jaundice, or if you are taking HIV medicines (saquinavir or ritonavir). Before starting R-Cinex 600 Tablet, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult your doctor before taking R-Cinex 600 Tablet if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking R-Cinex 600 Tablet as it passes into breast milk. R-Cinex 600 Tablet may cause dizziness, and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking R-Cinex 600 Tablet as it could lead to increased drowsiness, dizziness and liver damage.

Drug-Drug Interactions

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IsoniazidLomitapide
Critical

Drug-Drug Interactions

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How does the drug interact with R-Cinex 600 Tablet:
When Lovastatin is taken with R-Cinex 600 Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking R-Cinex 600 Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with R-Cinex 600 Tablet:
When Lomitapide is taken with R-Cinex 600 Tablet, R-Cinex 600 Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking R-Cinex 600 Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
How does the drug interact with R-Cinex 600 Tablet:
When R-Cinex 600 Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with R-Cinex 600 Tablet is not recommended, it taken can be taken if prescribed by the doctor.
RifampicinSaquinavir
Critical
How does the drug interact with R-Cinex 600 Tablet:
Taking saquinavir with R-Cinex 600 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
When ranolazine is taken with R-Cinex 600 Tablet, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
Taking pirfenidone with R-Cinex 600 Tablet can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
Taking darunavir with R-Cinex 600 Tablet can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
When Indinavir is taken with R-Cinex 600 Tablet, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
Taking Voriconazole with R-Cinex 600 Tablet can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with R-Cinex 600 Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
Co-administration of Glimepiride with R-Cinex 600 Tablet may interfere with blood glucose control and reduce the effectiveness of Glimepiride.

How to manage the interaction:
Although there is a possible interaction, Glimepiride can be taken with R-Cinex 600 Tablet if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.

  • Foods rich in vitamin C such as kiwi, broccoli, and bell pepper helps in improving the immune system. 

  • Avoid processed and fried foods.

  • Warm ginger tea or warm soup can help in providing relief from cough.

  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.

  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

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Alcohol

Safe if prescribed

Avoid alcohol consumption while taking R-Cinex 600 Tablet as it could lead to increased drowsiness, dizziness and liver damage.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, your doctor will prescribe R-Cinex 600 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

R-Cinex 600 Tablet passes into breast milk. Do not breastfeed while taking R-Cinex 600 Tablet.

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Driving

Safe if prescribed

R-Cinex 600 Tablet may cause dizziness, drowsiness, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking R-Cinex 600 Tablet if you have liver impairment/liver disease.

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking R-Cinex 600 Tablet.

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Children

Safe if prescribed

Please consult your doctor. Your doctor may suggest suitable dose and dosage form based on your child's age, body weight and medical condition. Kid tablets could be used in children if prescribed by the doctor.

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Heart

R-Cinex 600 Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

R-Cinex 600 Tablet is not recommended for use in elderly patients as it can lead to side effects.

FAQs

R-Cinex 600 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis.

R-Cinex 600 Tablet is a combination of two anti-tuberculosis drugs, namely: Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, R-Cinex 600 Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Do not stop taking R-Cinex 600 Tablet despite symptomatic relief. To treat your condition effectually, continue taking R-Cinex 600 Tablet for as long as it has been prescribed for you.

Do not take R-Cinex 600 Tablet along with antacids as it might decrease the effectiveness of R-Cinex 600 Tablet. Maintain a minimum gap of 1hour between both.

Consult your doctor before taking R-Cinex 600 Tablet with other medicines. Medicines used to treat TB such as PAS (P-amino salicylic acid) and cycloserine should be taken 8hours apart from R-Cinex 600 Tablet.

R-Cinex 600 Tablet contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer. Avoid these foods while taking R-Cinex 600 Tablet.

R-Cinex 600 Tablet might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking R-Cinex 600 Tablet. Consult your doctor if you have any concerns regarding this; your doctor may suggest an alternate method of contraception.

R-Cinex 600 Tablet may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time even after you stop taking R-Cinex 600 Tablet. Do not worry as it is a common side-effect of R-Cinex 600 Tablet.

Yes, R-Cinex 600 Tablet might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking R-Cinex 600 Tablet.

R-Cinex 600 Tablet may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking R-Cinex 600 Tablet.

Yes, R-Cinex 600 Tablet may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking R-Cinex 600 Tablet to check how your liver is functioning.

Yes, R-Cinex 600 Tablet can cause temporary discoloration of urine and sweat. This is a common and harmless side effect.

R-Cinex 600 Tablet is a combination of two anti-tuberculosis drugs, Rifampicin and Isoniazid. It is used in the treatment of Tuberculosis.

Before using R-Cinex 600 Tablet, you should learn about its use, side effects, and limitations.

If you forget a dose of R-Cinex 600 Tablet, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.

The best time to take R-Cinex 600 Tablet is 30 minutes before food or 2 hours after food. This helps your body absorb the medication more effectively.

Store R-Cinex 600 Tablet in a cool, dry place out of sunlight and children's reach. Check the expiration date regularly. To dispose of it, place it in a plastic bag and throw it away in household trash. Never flush it down the toilet or sink.

You should avoid alcohol while taking R-Cinex 600 Tablet strictly to ensure safety and efficacy, as it can increase the risk of liver damage when combined with medications like Isoniazid and Rifampicin.

Common side effects of R-Cinex 600 Tablet may include drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.

Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.

R-Cinex 600 Tablet is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RCI0007

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