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  3. Refnios 1 gm Injection 1's

Refnios 1 gm Injection 1's, Pack of 1
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Composition :

CEFAZOLIN-1GM

Manufacturer/Marketer :

Aionios Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Refnios 1 gm Injection 1's

Refnios 1 gm Injection 1's belongs to the group of antibiotics called 'cephalosporin' used to treat various bacterial infections of the nose, lungs, ear, bones, joints, skin, urinary tract, prostate gland and reproductive system. Besides this, Refnios 1 gm Injection 1's also used before surgeries to prevent post-surgical bacterial infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Refnios 1 gm Injection 1's does not work against infections caused by the virus, including cold and flu.

Refnios 1 gm Injection 1's contains 'Cefazolin' works by interfering with the formation of bacterial cell walls, thereby impairing the bonds that hold the bacterial cell wall together. This allows holes to appear in the bacterial cell walls, which kills the bacteria. Thus, it helps in treating and preventing the spread of infections.

You are advised to take Refnios 1 gm Injection 1's for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience injection site reactions (pain, swelling, redness), vomiting, allergic reaction, nausea, indigestion, diarrhoea, lightheadedness and dizziness. Most of these side effects of Refnios 1 gm Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Some patients may experience ‘Clostridium difficile associated diarrhoea (CDAD)’ a condition in which healthy bacteria in the colon (intestine) are disrupted.

If you are allergic to Refnios 1 gm Injection 1's, penicillins or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Refnios 1 gm Injection 1's. Drive only if you are alert as Refnios 1 gm Injection 1's may cause dizziness. You are recommended to complete the full course of Refnios 1 gm Injection 1's as prescribed by your doctor for effective results. Please do not take Refnios 1 gm Injection 1's on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. 

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Refnios 1 gm Injection 1's will be administered by a nurse or doctor.• Do not self-administer

Medicinal Benefits

Refnios 1 gm Injection 1's belongs to the group of antibiotic medicines called cephalosporins used to treat various bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease).  It is also used before surgeries to prevent post-surgical bacterial infections. Refnios 1 gm Injection 1's contains Cefazolin is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and some anaerobic bacteria.  Refnios 1 gm Injection 1's works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections.

How Refnios 1 gm Injection 1's Works

Refnios 1 gm Injection 1's contains 'Cefazolin' works by interfering with the formation of bacterial cell walls, thereby impairing the bonds that hold the bacterial cell wall together. This allows holes to appear in the bacterial cell walls, which kills the bacteria. Thus, it helps in treating and preventing the spread of infections.

Storage

Store in a cool and dry place away from sunlight
Side effects of Refnios 1 gm Injection
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Refnios 1 gm Injection 1's

Overdose of Refnios 1 gm Injection 1's may cause seizures. Since this medicine is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience symptoms of overdose.

Drug Warnings

If you are allergic to Refnios 1 gm Injection 1's, penicillins or any other medicines, please tell your doctor. If you have kidney or liver problems, diarrhoea, haemolytic anaemia (reduction in red blood cells that may make your skin pale yellow and cause breathlessness or weakness), kidney or gall stones, inflammation of the large intestine, inform your doctor before taking Refnios 1 gm Injection 1's. Do not take Refnios 1 gm Injection 1's on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Do not take antacids and calcium-containing products along with Refnios 1 gm Injection 1's; maintain a gap of 2-3 hours between both. If you are pregnant or breastfeeding, please inform your doctor before taking Refnios 1 gm Injection 1's. Use Refnios 1 gm Injection 1's with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects. You are recommended to complete the full course of Refnios 1 gm Injection 1's as prescribed by your doctor for effective results. Drive only if you are alert as Refnios 1 gm Injection 1's may cause dizziness. Avoid alcohol consumption while taking Refnios 1 gm Injection 1's to prevent unpleasant side-effects. Inform your doctor about all the medicines you are taking and about your health condition to rule out any undesirable side-effects. 

Drug-Drug Interactions

verifiedApollotooltip
CefazolinRifampicin
Severe
CefazolinHeparin
Severe

Drug-Drug Interactions

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CefazolinRifampicin
Severe
How does the drug interact with Refnios 1 gm Injection:
Taking rifampicin with Refnios 1 gm Injection may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Refnios 1 gm Injection and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CefazolinHeparin
Severe
How does the drug interact with Refnios 1 gm Injection:
When Refnios 1 gm Injection is used with Heparin, it enhances the effects of heparin.

How to manage the interaction:
Although taking Heparin and Refnios 1 gm Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, consult the doctor if you experience bleeding, bruising, throwing up, headache, feeling lightheaded, feeling weak, or blood in your urine or stools. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Refnios 1 gm Injection 1's to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can restore the good bacteria of the intestine.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread, brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Refnios 1 gm Injection 1's.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and tobacco to treat your condition effectively.
  • To cure your condition effectually complete the full course of Refnios 1 gm Injection 1's even though you find symptomatic relief.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Refnios 1 gm Injection 1's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consuming alcohol while taking Refnios 1 gm Injection 1's to prevent unpleasant side-effects.

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Pregnancy

Caution

Refnios 1 gm Injection 1's is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Refnios 1 gm Injection 1's may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Refnios 1 gm Injection 1's may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Refnios 1 gm Injection 1's.

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Liver

Caution

Take Refnios 1 gm Injection 1's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Refnios 1 gm Injection 1's should be used in patients with kidney diseases with extreme caution as Refnios 1 gm Injection 1's may cause renal toxicity. Dose adjustments are necessary.

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Children

Safe if prescribed

Refnios 1 gm Injection 1's is safe for children if prescribed by a doctor. Do not use Refnios 1 gm Injection 1's in a child without a doctor's advice. Refnios 1 gm Injection 1's should never be used in a premature baby, or in any new-born baby who has jaundice (yellowing of the skin or eyes).

Have a query?

FAQs

Refnios 1 gm Injection 1's is used to treat bacterial infections of the nose, lungs, ear, bones, joints, skin, urinary tract, prostate gland and reproductive system. Besides this, it is also used before surgeries to prevent post-surgical bacterial infections.

Refnios 1 gm Injection 1's contains Cefazolin which works by interfering with the formation of bacterial cell walls, thereby impairing the bonds that hold the bacterial cell wall together. This process ultimately disrupts the formation of bacterial cell wall formation, which kills the bacteria. Thus, it helps in treating and preventing the spread of infections.

Diarrhoea might be a side-effect of Refnios 1 gm Injection 1's. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Refnios 1 gm Injection 1's even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).

Refnios 1 gm Injection 1's may interfere with urine test (for sugar) and Coomb’s test (blood test) giving false-positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Refnios 1 gm Injection 1's.

Refnios 1 gm Injection 1's should be used with caution in patients with kidney problems as it may increase the risk of adverse effects. Therefore, inform your doctor if you have any kidney problems before taking Refnios 1 gm Injection 1's so that the dose may be adjusted accordingly.

Consult the doctor if you think Refnios 1 gm Injection 1's isn’t working for you. Your doctor may increase the dose or prescribe alternate medication based on your condition.

Consult the doctor if your condition does not get better even after completing the duration of treatment or if your condition worsens during treatment with Refnios 1 gm Injection 1's.

In some cases, Refnios 1 gm Injection 1's may cause side effects like injection site reactions (pain, swelling, redness), vomiting, allergic reaction, nausea, indigestion, diarrhoea, lightheadedness and dizziness. Most of these side effects of Refnios 1 gm Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Unit No: 105, First floor, No:18/1, Sufiya Elite Cunnigham Road, Bangalore – 560001
Other Info - REF0198

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

May 20, 2025 | 6:19 PM IST

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Reference

  1. https://www.drugs.com/cdi/cefazolin.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050779s019lbl.pdf

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