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compositionComposition:CEFPROZIL-250MG
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Prescription Medicine
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Refzil O Suspension is used to treat bacterial infections. It contains Cefprozil which works by inhibiting the growth of bacteria. Sometimes, this medicine may cause side effects such as stomach pain, dizziness, diarrhoea, nausea, and vomiting. Inform the doctor if you are giving any other medications to your child, or if they have any pre-existing medical conditions.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFPROZIL-250MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Refzil O Suspension

Refzil O Suspension belongs to a class of medications called ‘Antibiotics’ used to treat bacterial infections. It is used in the treatment of various bacterial infections such as pharyngitis (sore throat), tonsillitis (swollen tonsils), otitis media (middle ear infection), sinusitis (sinus infection), bronchitis (inflammation of the bronchi or lower respiratory tract infection) and skin infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce toxins that can damage tissues and make you sick. Refzil O Suspension is ineffective against viral infections, such as the common cold or flu.

Refzil O Suspension contains ‘Cefprozil’, which is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Thus, it helps treat and prevent the spread of infections.

You should give Refzil O Suspension to your child exactly as prescribed by your doctor. The common side-effects of Refzil O Suspension are nausea, diarrhoea, diaper rash, and vaginal itching or discharge. It may also cause abnormal liver function tests and decreased blood cell (WBC) count. These side effects usually don't require medical attention. Inform your doctor immediately if any of these side effects persist or get worse.

It is not recommended to give Refzil O Suspension if your child is allergic to any antibiotics, including penicillin and cephalosporin antibiotics. Before giving Refzil O Suspension, inform your doctor if your child has intestinal problems such as colitis (inflammation of the intestine) and kidney diseases. Do not give Refzil O Suspension to your child on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infection. Refzil O Suspension should be used with caution in children by consulting a doctor.

Uses of Refzil O Suspension

Refzil O Suspension is used to treat Bacterial infections. The detailed uses of Refzil O Suspension are as follows:

  • Treatment of Bacterial Infections: Refzil O Suspension is used to treat various bacterial infections.
  • Respiratory Tract Infections: Refzil O Suspension is effective against sinusitis, bronchitis, and pneumonia, helping clear infections in the lungs and airways.
  • Ear and Throat Infections: Refzil O Suspension is used to treat middle ear infections (otitis media), strep throat, and tonsillitis.
  • Skin and Soft Tissue Infections: Refzil O Suspension helps treat cellulitis and other bacterial skin infections, preventing the spread of harmful bacteria.

Key Benefits

Refzil O Suspension contains ‘Cefprozil’, which is a cephalosporin antibiotic. It acts by disrupting the formation of the cell wall (outer layer), which is essential for bacteria’s survival, thereby killing the bacteria. It is a broad-spectrum antibiotic and acts against both gram-positive and gram-negative bacteria. It can effectively treat bacterial infections such as pharyngitis (sore throat), tonsillitis (swollen tonsils), otitis media (middle ear infection), sinusitis (sinus infection), bronchitis (inflammation of the bronchi or lower respiratory tract infection), and skin infections.

Side effects of Refzil O Suspension 30 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.
  • Secondary infections must be reported to your doctor.
  • Watch your diet, consume low-fat foods, such as green leafy vegetables, fish, whole grains, nuts, etc., and avoid drinking alcohol.
  • Regularly do strengthening exercises to boost immunity.
  • Focus on losing weight as it can help improve body functioning and protect from infections.
  • Do not consume antibiotics unnecessarily. They kill the protective microorganisms in your body and can lead to secondary infections.

Directions for Use

  • Refzil O Suspension can be given with or without food.
  • Follow your doctor's instructions regarding the dosage and duration of the medication.
  • For powder for suspensions, reconstitute the powder with distilled water as per the labelled instructions.
  • Shake well before use. Administer the advised dose to the child using the measuring cup/measuring spoon/dropper.
  • Avoid using regular household spoons, as they may not measure the dose correctly.

How Refzil O Suspension Works

Refzil O Suspension contains Cefprozil, a cephalosporin antibiotic with bactericidal action (kills bacteria). It works by inhibiting the formation of the bacterial cell wall, an essential protective layer for their survival, and blocking protein synthesis. This helps treat infections and prevents the spread of infection.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Safe if prescribed

Refzil O Suspension is probably safe when used in children with liver diseases. However, please consult your doctor before giving this medication to your child.

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Kidney

Caution

Refzil O Suspension should be used with caution if your child has kidney problems. Your doctor may adjust the dose based on your child's medical condition.

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Children

Caution

Use Refzil O Suspension in children in prescribed doses. However, it is not recommended for children under 6 months of age. The dose will be determined by your doctor based on your child's condition, age and body weight.

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Heart

Caution

Please inform your doctor if your child has a history of heart disease. Your doctor will weigh the benefits and potential risks before prescribing Refzil O Suspension.

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Geriatrics

Not applicable

Refzil O Suspension is for paediatric patients only.

What if I have taken an overdose of Refzil O Suspension

Do not give your child more than the recommended dose, as this may result in an overdose, which can cause seizures. If an overdose is suspected, seek medical attention immediately. Keep Refzil O Suspension out of sight and reach of children.

Diet & Lifestyle Advise

  • Probiotics should be given to your child after completing the full course of Refzil O Suspension to restore some healthy bacteria in the intestines that may have been killed. Giving probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.

  • Include more fibre-enriched food in your child’s diet. Fibre-rich foods can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your child’s diet.

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Have a query?

How Soon It Starts Working

The time required for Refzil O Suspension to start to work: The time required for Refzil O Suspension to show its action is unknown. The time for which the effects of Refzil O Suspension last: The duration of action for Refzil O Suspension is unknown.

What if you forget to take Refzil O Suspension

If you miss giving a dose to the child, give it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and administer the next dose at the scheduled time. Do not double the dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep Refzil O Suspension out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Refzil O Suspension should be used with caution in children with kidney diseases. Do not give Refzil O Suspension to your child on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Your child may experience ‘Clostridium difficile associated diarrhoea (CDAD)’ after using Refzil O Suspension. So, please undergo an examination to rule out CDAD's chances if they experience diarrhoea following the use of Refzil O Suspension. Do not give Refzil O Suspension to your child for prolonged periods than recommended by your doctor. Long-term use can lead to superinfection (additional infection caused by other microbes).

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Refzil O Suspension may interact with other cephalosporin antibiotics, aminoglycoside antibiotics (amikacin, gentamicin, kanamycin, and streptomycin), and medicine used to treat gout or high uric acid levels (probenecid).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Refzil O Suspension should be used with caution in children with kidney diseases and intestinal problems such as colitis (colon inflammation).

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Refzil O Suspension is used to treat bacterial infections such as pharyngitis (sore throat), tonsillitis (swollen tonsils), otitis media (middle ear infection), sinusitis (sinus infection), bronchitis (inflammation of the bronchi or lower respiratory tract infection) and skin infections.
Refzil O Suspension contains Cefprozil which is used to treat bacterial infections. It works by inhibiting bacterial growth and disrupting the formation of the cell wall, an essential outer layer for the bacteria's survival.
The use of Refzil O Suspension may disrupt the natural gut flora, potentially leading to Clostridium difficile-associated diarrhoea. To prevent dehydration, give plenty of fluids to your child if they experience diarrhoea. Consider giving probiotics to your child after completing the antibiotic course to help restore the balance of gut bacteria. Consult a doctor if your child experience watery or bloody stools.
No, you should not give Refzil O Suspension to your child if they are allergic to penicillin, as they may develop cross-sensitivity to drugs with similar structures. Refzil O Suspension contains cefprozil, which has a structure similar to penicillin.
Refzil O Suspension does not treat a viral infection like the flu or a common cold. So if your child feels under the weather, it is best to consult the doctor to know if they need Refzil O Suspension for their condition.
The common side-effects of Refzil O Suspension are nausea, diarrhoea, diaper rash, and vaginal itching or discharge. It may also cause abnormal liver function tests and decreased white blood cell (WBC) count. These side effects usually do not require medical attention. However, inform your doctor immediately if any of these side effects persist or get worse.
The use of Refzil O Suspension for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your child’s mouth, a change in their vaginal discharge or other new symptoms.
Yes, Refzil O Suspension is safe if given in the dose and duration as prescribed by the doctor.
Yes, Refzil O Suspension is a cephalosporin antibiotic used to treat bacterial infections.
Do not stop giving Refzil O Suspension to your child without consulting the doctor. To treat the condition effectively, continue administering Refzil O Suspension for the full prescribed duration.
Refzil O Suspension starts working as soon as you start giving the medicine. However, it might take a few days to treat the infection completely. Therefore, finish the course of treatment as advised by the doctor.
Consult the doctor if your child does not feel better after using Refzil O Suspension or if your condition worsens during treatment. The doctor may adjust the dose or prescribe alternate medicine.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 050664S024,050665S024Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Cefprozil Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Cefprozil Cefprozil. 2024. [Accessed on 09 Jan. 2026]Check here
  4. Cefprozil. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic potential. NCBI. National Center for Biotechnology information. National library of Medicine. February 1993. [Accessed on 14th August 2024]Check here
  5. Cefprozil. National Library of Medicine. MedlinePlus. [Revised in January 2022]. [Accessed on 14th August 2024]Check here
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 28 Mar. 2019]Check here
  7. Sandoz Canada Inc. Cefprozil Tablets (cefprozil as cefprozil monohydrate). Tablets, 250 mg and 500 mg. [Revised in October 2020]. [Accessed on 14th August 2024] pm/00058690.PDFCheck here

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - REF0027
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