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  3. Regain Tablet 10's

Regain Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Regain Tablet is used to reduce musculoskeletal pain due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). It works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. Additionally, it helps by blocking nerve impulses or pain sensations sent by the brain, causing relaxation of the muscles. It may cause side effects such as drowsiness, constipation, diarrhoea, stomach upset, slight discolouration of urine, and ringing or buzzing sounds in the ears. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CHLORZOXAZONE-250MG + DICLOFENAC-50MG + PARACETAMOL-325MG

Manufacturer/Marketer :

Spic Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Regain Tablet

Regain Tablet is used in the reduction of musculoskeletal pain due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). Musculoskeletal pain can be caused due to soft tissue (muscle, tendon, and ligaments) injury.

Regain Tablet is a combination of Diclofenac, paracetamol, and chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling. Paracetamol enhances the pain-relieving action of Diclofenac. Chlorzoxazone helps by blocking nerve impulses sent by the brain and causes relaxation of muscles.

Like all medicines, Regain Tablet may cause side effects, although not everybody gets them. Most of the side effects of Regain Tablet are drowsiness, constipation, diarrhoea, stomach upset, slight discolouration of urine, and ringing or buzzing sounds in the ears. In case of any discomfort, speak with your doctor.

Regain Tablet can be taken with or after the meal. To avoid stomach upset Regain Tablet can be taken with food or milk. It should be swallowed whole with a glass of water. Do not take Regain Tablet if your pain lasts for more than ten days or if the fever lasts for more than three days. Do not take a double dose if you miss one dose.

Do not take Regain Tablet if you are allergic to painkillers like aspirin, paracetamol, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Regain Tablet may be associated with a small increase in the risk of heart attack (myocardial infarction).

Uses of Regain Tablet

Regain Tablet used in the treatment of Musculoskeletal pain. The detailed uses of Regain Tablet are as follows:

  • Pain Relief: Regain Tablet provides effective relief from various types of pain, including musculoskeletal pain, muscle pain, joint pain, body pain, toothache, headache, and rheumatic pain, helping to alleviate discomfort and improve daily activities.
  • Muscle Relaxation: Regain Tablet helps to relieve muscle spasms, providing relaxation and comfort, especially in conditions like muscle strain and joint stiffness.
  • Fever Reduction: Regain Tablet also helps to reduce the fever associated with pain and discomfort.

Directions for Use

  • Regain Tablet should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Regain Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Regain Tablet is composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone.
  • Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site.
  • Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of Diclofenac.
  • Chlorzoxazone, is a muscle relaxant that helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

How Regain Tablet Works

Regain Tablet is a fixed-dose combination composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of Diclofenac. The third medicine, Chlorzoxazone, is a muscle relaxant that helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Regain Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.

What if I have taken an overdose of Regain Tablet

Do not take more than the prescribed dose of Regain Tablet as it may cause serious side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Intake of Regain Tablet should be avoided in liver disease (like jaundice) and cardiovascular disease (like coronary heart disease).
  • Contact your doctor if you have signs of liver disease, such as feeling exhausted, dark urine, not feeling hungry, stomach pain or upset, light coloured stools or yellow skin/eyes.
  • After taking if you have possible allergic symptoms like difficulty in breathing, difficulty in swallowing, lips/face/throat swelling, chest tightness, or skin rash, contact the doctor immediately.
  • Ensure your doctor is aware if you are pregnant or planning to get pregnant, breastfeeding, allergic to Regain Tablet or any other painkillers like aspirin, have a stomach ulcer or gastric bleeding, or taking any other OTC multivitamins or multi-mineral supplements.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
ChlorzoxazoneMorphine
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Regain Tablet:
Co-administration of Regain Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Regain Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
ChlorzoxazoneMorphine
Severe
How does the drug interact with Regain Tablet:
Using Morphine together with Regain Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Regain Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ChlorzoxazoneTapentadol
Severe
How does the drug interact with Regain Tablet:
Taking Tapentadol with Regain Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Regain Tablet with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
DiclofenacFurosemide
Severe
How does the drug interact with Regain Tablet:
Concomitant administration of Regain Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Regain Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
DiclofenacRamucirumab
Severe
How does the drug interact with Regain Tablet:
Co-administration of Regain Tablet and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Regain Tablet and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacTenofovir alafenamide
Severe
How does the drug interact with Regain Tablet:
Co-administration of Regain Tablet and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Regain Tablet and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
DiclofenacTolmetin
Severe
How does the drug interact with Regain Tablet:
Taking Regain Tablet with Tolmetin may increase the risk of side effects.

How to manage the interaction:
There may be a possible interaction between Regain Tablet and Tolmetin but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacSirolimus
Severe
How does the drug interact with Regain Tablet:
Co-administration of Regain Tablet with Sirolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Regain Tablet and Sirolimus can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
DiclofenacIbuprofen
Severe
How does the drug interact with Regain Tablet:
Taking Regain Tablet and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Regain Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacPonatinib
Severe
How does the drug interact with Regain Tablet:
Taking Regain Tablet with Ponatinib can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Regain Tablet and Ponatinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Regain Tablet is commonly prescribed for relieving pain in both acute and chronic conditions and in cases of fever. Do not take the drug beyond its suggested dose and frequency.
  • Avoid driving while consuming Regain Tablet as it can cause dizziness in some individuals and hamper your focus and reflexes.
  • Avoid concomitant consumption of drugs containing the same chemicals as Regain Tablet as it can lead to overdosage and unwanted side effects.
  • Immediately consult your doctor in case of persistent side effects like stomach pain on consumption of Regain Tablet .
  • Avoid consuming alcohol while you are on Regain Tablet .

Habit Forming

No

Therapeutic Class

ANALGESICS

Regain Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol should not be consumed with Regain Tablet as it leads to excessive drowsiness

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Pregnancy

Consult your doctor

Only consume Regain Tablet , if you are prescribed by a doctor

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Breast Feeding

Consult your doctor

Regain Tablet does not pass on to the child significantly via breast milk, consult your doctor before using Regain Tablet .

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Driving

Unsafe

Regain Tablet may affect driving ability as it causes dizziness.

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Liver

Caution

Regain Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Regain Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

bannner image

Children

Unsafe

Regain Tablet is not recommended for children below 12 years of age without doctor's consent. For children above 12 years, dose to be adjusted and recommended by a child specialist only.

Have a query?

FAQs

Regain Tablet is used to treat musculoskeletal pain due to tissue injury, post-surgery inflammation‚ and oedema (swollen tissue with fluid).

No, Regain Tablet should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For the best results of Regain Tablet , take it in doses and duration mentioned by your doctor.

No, it is not advisable to take Regain Tablet with depression medication. Please inform your doctor if you are taking depression medicine before starting Regain Tablet .

Yes, Regain Tablet is a short term medication and if you feel better you can stop taking Regain Tablet , but only after consulting your doctor.

Regain Tablet is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.

No, Regain Tablet is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer or gastric bleeding. Do not take Regain Tablet in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.

It depends on whether your cough and cold pills contains diclofenac, paracetamol and Chlorzoxazone or not. If it contains these three medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.

No, do not take Regain Tablet until prescribed by your doctor. For example, your shoulder pain may be due to lungs, spleen or gallbladder problem. Your back pain may be due to kidney stone, pancreas swelling, or in women, pelvic disorders. Your arm pain (especially left arm) may be due to heart attack (myocardial infarction).

Regain Tablet is a combination of a muscle relaxant (Chlorzoxazone) and two pain relieving medicines (Diclofenac and Paracetamol).

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.

Regain Tablet is not intended to treat toothache. It is used to reduce musculoskeletal pain.

Avoid simultaneous consumption of other painkillers or cough and cold medicines with this Regain Tablet , as it may lead to an overdose.

No, it is not indicated to treat gastritis. It may worsen your condition.

It may help ease pain associated with period pain. However, it should only be used if recommended by the doctor.

It may help ease headaches. However, it should be used only if recommended by the doctor.

Regain Tablet usually takes effect within 30 minutes to an hour of intake.

No, it does not contain steroids. It combines one muscle relaxant medication and two pain relieving medicines.

Yes, in some cases, Regain Tablet may cause acidity.

Yes, Regain Tablet may cause drowsiness, although not everybody gets it. If you experience any discomfort, speak with your doctor.

No, Regain Tablet is not intended to treat loose motion. It is meant to treat musculoskeletal pain.

Yes, it can be used to treat tissue or ligament injury. However, it should be used only if recommended by a doctor.

Regain Tablet may cause constipation, although not everybody gets it. If you experience any discomfort, speak with your doctor.

Regain Tablet is safe if used as advised by the doctor. Follow your doctor's instructions.

It may cause common side effects like nausea and vomiting in some patients, although not everybody gets them. If you experience any discomfort, speak with your doctor.

Yes, it may lead to dizziness, although not everybody gets it. If you experience any discomfort, consult your doctor.

Yes, long-term usage of Regain Tablet may be harmful to the kidney.

Store in a cool and dry place away from sunlight. Keep out of the sight and reach of children.

Yes, it should be taken with food or after food.

Regain Tablet should not be used during pregnancy and by nursing mothers unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Regain Tablet .

Regain Tablet is not recommended for children below 12 years of age without a doctor's consent. For children above 12 years, the dose is to be adjusted and recommended by a child specialist only.

Alcohol should not be consumed with Regain Tablet as it leads to excessive drowsiness.

Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Taking more than the recommended dosage does not provide additional pain relief and can increase the risk of adverse effects.

Country of origin

India

Manufacturer/Marketer address

SPIC House 88 Mount Road,Guindy, Chennai 600032, India
Other Info - REG0001

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 15, 2025 | 9:28 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.unitedpharmacies.md/Dicoliv-MR-Diclofenac-Potassium-Paracetamol-Chlorzoxazone.html
  2. https://www.medicines.org.uk/emc/files/pil.2660.pdf
  3. https://www.medicines.org.uk/emc/files/pil.10547.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/psg/PSG_011300.pdf
  5. https://www.sciencedirect.com/topics/neuroscience/chlorzoxazone
  6. https://www.nhs.uk/conditions/nsaids/

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