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compositionComposition:METFORMIN-500MG+METHYLCOBALAMIN-750MCG
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Prescription Medicine
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Rejumet Tablet is used in the treatment of Type 2 diabetes mellitus. It contains Metformin and Methylcobalamin, which decrease liver glucose production and intestinal glucose uptake, and also helps treat vitamin B12 deficiency. It may cause side effects such as changes in taste, nausea, vomiting, diarrhoea, headache, loss of appetite, and sweating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METFORMIN-500MG+METHYLCOBALAMIN-750MCG

Manufacturer/Marketer :

Fourrts India Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Rejumet Tablet

Rejumet Tablet is an oral prescription medicine used to manage type 2 diabetes and support healthy nerve function. It helps control blood sugar levels when diet and exercise alone are not enough, while also protecting the nerves from damage associated with diabetes. This combination is particularly useful for individuals who require blood sugar management alongside nerve health support.

For the best results, you must take this medicine consistently every day, exactly as directed by your doctor. It is typically taken with meals to reduce the chance of experiencing an upset stomach. Combining this medication with a balanced, low-glycaemic diet and regular physical activity will significantly improve your overall blood sugar control.

While taking Rejumet Tablet , some people may experience mild side effects like nausea, diarrhoea, or a metallic taste in the mouth. However, you should contact your doctor immediately if you experience severe symptoms such as deep, rapid breathing, severe muscle weakness, or extreme sleepiness.

Talk to your doctor before starting this medicine if you have a history of kidney disease, liver damage, or heart problems. Do not take this if you have severe kidney disease, as this increases the risk of serious complications.

This medicine can interact with certain other treatments, contrast dyes used in medical scans, and excessive alcohol. Women who are pregnant, breastfeeding, or planning a pregnancy, as well as elderly individuals, should consult their doctor before starting this treatment.

 

Uses of Rejumet Tablet

Rejumet Tablet is used to treat Type 2 diabetes mellitus. The detailed uses of Rejumet Tablet are as follows:

  • Type 2 Diabetes Mellitus: Helps lower and stabilise blood sugar levels in the body.
  • Diabetic Neuropathy: Helps support, repair, and protect nerves from damage associated with long-term high blood sugar.
  • Prevention of Vitamin B12 Deficiency: Helps prevent the low vitamin B12 levels that can sometimes occur with long-term blood sugar-lowering therapies.

 

Key Benefits

Rejumet Tablet helps manage blood sugar levels while supporting healthy nerve function. By combining blood sugar control with nutritional support for nerves, it helps reduce diabetes-related complications and improves overall wellbeing.

  • Helps Maintain Healthy Blood Sugar Levels: By improving blood sugar control, Rejumet Tablet helps reduce fluctuations in glucose levels and lowers the risk of long-term diabetes-related complications affecting the heart, kidneys, eyes, and blood vessels.
  • Supports Healthy Nerve Function: Rejumet Tablet helps nourish and protect nerves, reducing symptoms such as tingling, numbness, burning sensations, and discomfort associated with diabetic neuropathy.
  • Promotes Better Daily Comfort and Long-Term Health: By supporting both blood sugar management and nerve health, Rejumet Tablet helps improve mobility, physical comfort, and quality of life while contributing to better long-term diabetes management.
     
Side effects of Rejumet Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Frequent flossing and brushing can help remove bacteria and debris that can give your teeth a metallic taste.
  • The metallic flavor may be caused by a zinc deficiency. Eat foods like meat, chicken, and oysters that are high in zinc.
  • Reducing the intake of foods with strong aromas, like onions and garlic, as they may intensify the taste of metallic substances.
  • Avoid smoking and tobacco products as they may intensify the metallic flavor.

Directions for Use

  • Take Rejumet Tablet with food to avoid stomach upset or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure its safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Rejumet Tablet Works

Rejumet Tablet works through the combined action of its two active components to manage your health. The first active ingredient, metformin, helps lower blood sugar in three ways: it decreases the amount of glucose produced by your liver, reduces the amount of sugar absorbed by your intestines, and improves your body's sensitivity to insulin, allowing your cells to use sugar more effectively. The second active ingredient, methylcobalamin, is a form of vitamin B12 that plays a vital role in nerve health. It helps produce myelin, which is the protective sheath that covers and insulates your nerve fibres. By promoting the repair and regeneration of these nerve cells, it helps restore proper nerve function and eases the symptoms of nerve pain.
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Alcohol

Unsafe

Alcohol may increase the risk of side effects and worsen the condition.

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Pregnancy

Consult your doctor

Rejumet Tablet is a category B drug. It should be used in pregnant women only if clinically needed.

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Breast Feeding

Unsafe

Rejumet Tablet should not be used in breastfeeding mothers as it may get secreted in the breast milk and cause unwanted effects in the nursing babies.

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Driving

Safe if prescribed

Rejumet Tablet does not affect your ability to drive.

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Liver

Caution

Rejumet Tablet should be taken with caution, especially if you have a history of liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Rejumet Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Consult your doctor

Rejumet Tablet can be used in children above 10 years of age if clinically required.

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Heart

Unsafe

Rejumet Tablet is not recommended for use in heart patients due to its adverse effects.

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Geriatrics

Caution

Rejumet Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Rejumet Tablet .

What if I have taken an overdose of Rejumet Tablet

Seek immediate medical attention right away if you suspect an overdose. Watch for signs of severe low blood sugar or lactic acidosis.

Diet & Lifestyle Advise

  • Monitor your blood sugar levels regularly as advised by your healthcare team.
  • Focus on a diet rich in high-fibre, low-glycaemic foods like whole grains, vegetables, and lean proteins.
  • Maintain a regular exercise routine, such as walking or cycling, to help your body use insulin more efficiently.
  • Inspect your feet daily for any cuts, blisters, redness, or swelling, which is crucial when managing diabetic nerve conditions.
  • Limit your alcohol consumption, as alcohol can interfere with blood sugar levels and increase risks.
     
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How Soon It Starts Working

The time required for Rejumet Tablet to start to work: The time required for Rejumet Tablet to show its action is unknown. The time for which the effects of Rejumet Tablet last: The duration of action for Rejumet Tablet is unknown.

What if you forget to take Rejumet Tablet

Take the missed dose with food as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store the tablets at room temperature, ideally between 20°C and 25°C.

Drug Warnings

  • Inform all your healthcare providers, including dentists and specialists, that you are taking this medicine.
  • You must temporarily stop taking this medicine before any surgical procedure or medical imaging scan that requires iodinated contrast dye; talk to your doctor for specific instructions.
  • Drink plenty of water throughout the day to stay hydrated and support healthy kidney function.
  • Do not make sudden changes to your diet or exercise routine without consulting your doctor, as this can affect your blood sugar control.

Drug-Drug Interactions

verifiedApollotooltip
  • Diuretics (water tablets) and certain blood pressure medicines (e.g., ACE inhibitors): Taking these medicines with Rejumet Tablet may affect kidney function and increase the risk of side effects. Your doctor may recommend monitoring your kidney function, particularly when starting or adjusting treatment.
  • Cimetidine: Cimetidine may increase the levels of Rejumet Tablet in the bloodstream by reducing its elimination, potentially increasing the risk of side effects. Your doctor may recommend an alternative medicine or closer monitoring.
  • Iodinated contrast media (contrast dyes): Contrast agents used during certain X-rays or CT scans may temporarily affect kidney function, increasing the risk of medicine accumulation and serious side effects. Your doctor may advise temporarily stopping Rejumet Tablet before and after the procedure until kidney function has been reassessed.
     
Mecobalamin + MetforminIopamidol
Critical
Mecobalamin + MetforminGatifloxacin
Critical

Drug-Drug Interactions

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Mecobalamin + MetforminIopamidol
Critical
How does the drug interact with Rejumet Tablet:
Co-administration of Iopamidol with Mecobalamin and Metformin can increase the risk of side effects.

How to manage the interaction:
Taking Mecobalamin and Metformin with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Mecobalamin + MetforminGatifloxacin
Critical
How does the drug interact with Rejumet Tablet:
Co-administration of Mecobalamin and Metformin with Gatifloxacin can cause both hypoglycaemia (low blood glucose) and, less frequently, hyperglycaemia (high blood glucose).

How to manage the interaction:
There is a possibility of interaction between Mecobalamin and Metformin and Gatifloxacin but they can be taken together if a doctor has prescribed them. Do not discontinue without consulting a doctor.
Mecobalamin + MetforminIopromide
Critical
How does the drug interact with Rejumet Tablet:
Co-administration of Iopromide with Mecobalamin and Metformin can increase the risk of kidney problems.

How to manage the interaction:
Taking Iopromide with Mecobalamin and Metformin is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Mecobalamin + MetforminIodixanol
Critical
How does the drug interact with Rejumet Tablet:
Co-administration of Iodixanol with Mecobalamin and Metformin can increase the risk of side effects.

How to manage the interaction:
Taking Mecobalamin and Metformin with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Mecobalamin + MetforminIomeprol
Critical
How does the drug interact with Rejumet Tablet:
Co-administration of Iomeprol with Mecobalamin and Metformin can increase the risk of side effects.

How to manage the interaction:
Taking Mecobalamin and Metformin with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Mecobalamin + MetforminIodamide
Critical
How does the drug interact with Rejumet Tablet:
Co-administration of Mecobalamin and Metformin with Iodamide may increase the risk of kidney function.

How to manage the interaction:
Taking Mecobalamin and Metformin with Iodamide is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
Mecobalamin + MetforminMetrizamide
Critical
How does the drug interact with Rejumet Tablet:
Co-administration of Mecobalamin and Metformin with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Mecobalamin and Metformin with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Mecobalamin + MetforminTopiramate
Severe
How does the drug interact with Rejumet Tablet:
The combined use of Mecobalamin and Metformin and Topiramate may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Co-administration Mecobalamin and Metformin with Topiramate can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as respiratory distress, fatigue, loss of appetite, consult the doctor immediately. Do not stop using any medication without a doctor's advice.
Mecobalamin + MetforminAcetazolamide
Severe
How does the drug interact with Rejumet Tablet:
Co-administration of Mecobalamin and Metformin with Acetazolamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Mecobalamin and Metformin with Acetazolamide, you can take these medicines together if prescribed by a doctor. However, if you have symptoms such as difficulty breathing, dizziness, chest pain or discomfort, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Mecobalamin + MetforminMethazolamide
Severe
How does the drug interact with Rejumet Tablet:
Co-administration of Mecobalamin and Metformin with Methazolamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Mecobalamin and Metformin and Methazolamide, you can take these medicines together if prescribed by a doctor. However, if you have symptoms such as fatigue, loss of appetite, slow or irregular heartbeat, breathing difficulty, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid drinking alcohol while taking Rejumet Tablet , as excessive alcohol intake may increase the risk of lactic acidosis, a rare but serious medical emergency.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Rejumet Tablet is used in the treatment of Type 2 diabetes mellitus.
Rejumet Tablet is a combination of Metformin and Methylcobalamin. Metformin reduces blood glucose levels by decreasing liver glucose production and intestinal glucose uptake. Methylcobalamin helps reduce vitamin B12 deficiency, which can occur due to the use of metformin.
Inform your doctor before having an X-ray or CT scan that you are taking Rejumet Tablet . Some imaging scans may involve the injection of contrast materials that contain iodine into your bloodstream, which may affect your kidney function.
Rejumet Tablet is recommended for the treatment of type 2 diabetes and not used for treating type 1 diabetes, a condition which occurs mainly due to deficiency of insulin.
Rejumet Tablet is recommended for treating type 2 diabetes in obese patients as this medicine may affect weight loss. However, if you experience excessive weight loss, consult your doctor immediately.
Rejumet Tablet may not cause significant hypoglycemia (a reduction in blood sugar levels). However, its action is to reduce blood glucose levels in diabetes patients and can cause hypoglycemia if taken together with other medicines to treat diabetes, so consult a doctor if you have severe or recurrent hypoglycemic episodes while using Rejumet Tablet .
The best diabetes medicine depends on various factors, including the type of diabetes (type 1 or 2), age, medical history, and other health conditions. What works for one person may not work for another. Consulting a healthcare professional is essential to determine the most effective treatment plan, as they will consider individual factors and develop a personalised approach tailored to your specific needs.
Do not take Rejumet Tablet if you have severe kidney damage, kidney failure, or are on dialysis. Additionally, individuals with metabolic acidosis, including diabetic ketoacidosis, should not take Rejumet Tablet . Pregnant or breastfeeding women should consult their doctor before taking Rejumet Tablet . It's essential to discuss your medical history and any underlying conditions with your doctor before starting Rejumet Tablet .
If you are pregnant or planning to become pregnant, consult your doctor before taking Rejumet Tablet . Your doctor will weigh the potential benefits and risks to determine whether it is safe for you to use during pregnancy.
The common side effects of Rejumet Tablet are changes in taste, nausea, vomiting, diarrhoea, headache, anorexia (loss of appetite), and sweating. Please consult your doctor if any of these side effects persist or worsen.
Avoid excessive consumption of alcohol along with Rejumet Tablet , as it may increase the risk of lactic acidosis.
It is best to take this medicine with meals to reduce the risk of common digestive side effects like nausea or diarrhoea. Talk to your doctor or pharmacist for specific advice.
The most serious, though rare, side effect is lactic acidosis, a buildup of acid in your blood. Seek immediate medical attention if you experience severe muscle pain, breathing difficulties, or extreme fatigue. Talk to your doctor if you have concerns.
Yes, if the scan requires a contrast dye, you may need to stop taking this medicine temporarily to protect your kidneys. Always talk to your doctor or radiologist before your procedure.
You should avoid or limit alcohol while taking this medicine. Alcohol increases the risk of dangerously low blood sugar and a serious condition called lactic acidosis. Talk to your doctor about safe alcohol limits.
Take the missed dose with food as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Talk to your pharmacist if you need clarification.

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Country of origin

India

Manufacturer/Marketer address

#1, Fourrts Avenue, Annai Indira Nagar, Okkiyam Thoraipakkam, Chennai, India.
Other Info - REJ0072
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