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Renoxi-Forte Tablet 10's is a combination medication used to treat chronic kidney disease (CKD). It contains acetylcysteine and pyridoxine, which help the body metabolism of fats, carbohydrates, and proteins, thereby assisting in maintaining energy balance in kidney disease patients. Common side effects include nausea, vomiting, diarrhoea, and abdominal pain.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
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More about the Product

Manufacturer/Marketer :

Rencord Life Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Renoxi-Forte Tablet 10's

Renoxi-Forte Tablet 10's is an oral suggested medicine that combines pyridoxine (vitamin B6) and acetylcysteine. It may be suggested to help manage elevated homocysteine levels and support kidney health in selected patients, particularly those at risk of contrast-induced kidney injury during imaging procedures. As evidence for its kidney-protective effects is mixed, its use should be based on an individual assessment by a healthcare professional. In some cases, doctors may also prescribe it as part of the management plan for chronic kidney disease or diabetic kidney disease.

For the best results, take this medicine consistently at the same time each day as directed by your healthcare provider. It should be taken with a full glass of water and can be taken with or without food. Maintaining a balanced, low-sodium diet and staying well hydrated may further support kidney health.

Some people may experience mild, temporary side effects such as nausea or an upset stomach, which usually improve as the body adjusts. However, seek immediate medical attention if you develop breathing difficulties, skin rashes, or swelling of the face.

Before starting treatment, inform your doctor about your medical history. Do not take this medicine if you are allergic to any of its ingredients. Tell your healthcare provider if you have asthma or active stomach ulcers, as these conditions may require closer monitoring.

This medicine may interact with certain blood pressure and heart medications. Limiting alcohol intake is advisable to reduce the risk of stomach irritation. If you are pregnant, planning to breastfeed, or are elderly, consult your doctor or pharmacist before starting this medicine.

Uses of Renoxi-Forte Tablet 10's

Renoxi-Forte Tablet 10's is used in the managment of chronic kidney disease (CKD). The detailed use of Renoxi-Forte Tablet 10's is as follows:

  • Reduction of elevated homocysteine levels in appropriate patients.
  • Prevention or reduction of the risk of contrast-induced kidney injury in selected patients undergoing imaging procedures with contrast dyes.
  • May be suggested as part of the management plan for chronic kidney disease (CKD), based on your doctor's clinical judgment.
  • May be used in selected patients with diabetic kidney disease, depending on individual treatment needs.
     

Key Benefits

This combination may help support kidney health by reducing oxidative stress and supporting normal metabolic processes in the body. Acetylcysteine helps replenish glutathione, an important natural antioxidant that protects cells from damage caused by harmful free radicals, while pyridoxine supports normal homocysteine metabolism. These effects may help support overall cellular health, including in the kidneys.

In patients at risk of contrast-induced kidney injury, this combination may sometimes be suggested to help reduce oxidative damage associated with contrast exposure. However, major clinical studies have produced mixed results, and a clear protective benefit has not been consistently confirmed. For this reason, it is not considered a proven standard treatment for preventing contrast-induced kidney injury and should be used according to your doctor's clinical judgment.

Additionally, this medicine supports healthy metabolic pathways in the body. Rather than relying on a single laboratory result, your doctor may monitor kidney function tests, such as serum creatinine, eGFR, and urine tests, to assess your individual response to treatment and help guide ongoing care.

Directions for Use

  • Take this medicine by mouth, exactly as directed by your doctor.
  • Swallow the tablet or capsule whole with a full glass of water. Do not crush, chew, or break it unless specifically instructed to do so.
  • You may take this medication with or without food, but keeping your routine consistent each day is highly recommended.
  • Drink plenty of fluids throughout the day to support your kidney function while on this medication.
     

How Renoxi-Forte Tablet 10's Works

Renoxi-Forte Tablet 10's is a combination of acetylecysteine and pyridoxine. Acetylcysteine: This ingredient acts as an antioxidant and a precursor of glutathione (meaning it helps the body produce glutathione, a natural substance that fights cell damage). It helps replenish vital glutathione stores, neutralize harmful free radicals, and reduce oxidative stress, which may help protect kidney cells from damage and support healthy blood flow within the kidneys. Pyridoxine (Vitamin B6): This component is a helper nutrient that the body needs to process proteins and support many metabolic functions. It helps lower levels of homocysteine, a naturally occurring chemical that, in high amounts, may be linked to blood vessel and kidney damage.
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Alcohol

Caution

It is not known if alcohol interacts with Renoxi-Forte Tablet 10's. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Consult your doctor

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor as there is no substantial research yet on the use of Renoxi-Forte Tablet 10's in breastfeeding/nursing mothers.

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Driving

Safe if suggested

Renoxi-Forte Tablet 10's may not affect your ability to drive or use machinery.

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Liver

Consult your doctor

Limited information was available about the use of Renoxi-Forte Tablet 10's in patients suffering from liver impairment. Please consult your doctor.

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Kidney

Consult your doctor

Limited information was available about the use of Renoxi-Forte Tablet 10's in patients suffering from kidney impairment. Please consult your doctor.

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Children

Consult your doctor

Limited information is available regarding the usage of Renoxi-Forte Tablet 10's in children, so please consult a doctor if you have any concerns.

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Heart

Consult your doctor

Limited information was available regarding the use of Renoxi-Forte Tablet 10's in patients with heart problems. Please consult your doctor.

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Geriatrics

Consult your doctor

Limited information is available regarding the usage of Renoxi-Forte Tablet 10's in elders, so please consult a doctor if you have any concerns.

What if I have taken an overdose of Renoxi-Forte Tablet 10's

If you suspect an accidental overdose, seek immediate medical attention or contact a local poison control center. Symptoms of an overdose may include severe nausea, vomiting, or stomach pain. Always bring the medication packaging with you to the hospital.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink an adequate amount of water daily as advised by your healthcare provider to help your kidneys filter waste efficiently.
  • Limit dietary sodium: Reduce your salt intake to help manage blood pressure and lessen the workload on your kidneys.
  • Manage blood sugar and blood pressure: Keep a close eye on your glucose and blood pressure levels, as keeping these in a healthy range is crucial for preventing further kidney decline.
  • Eat a kidney-friendly diet: Focus on fresh vegetables, lean proteins, and whole grains while limiting processed foods high in phosphorus and potassium, according to your doctor's guidance
     
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How Soon It Starts Working

The time required for Renoxi-Forte Tablet 10's to start to work: The time required for Renoxi-Forte Tablet 10's to show its action is unknown. 
The time for which the effects of Renoxi-Forte Tablet 10's last: The duration of action for Renoxi-Forte Tablet 10's is clinically unknown.

What if you forget to take Renoxi-Forte Tablet 10's

If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, talk to your doctor or pharmacist.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Always inspect the packaging and the appearance of the tablets before taking them to ensure they are intact.
  • Inform your radiologist that you are taking this medication if you are scheduled for any imaging scan that requires contrast dye.
  • Never share your medication with anyone else, even if they have similar symptoms or kidney conditions.
  • Keep a complete list of all medications, vitamins, and herbal supplements you take, and share it with your doctor before starting this combination.
  • Before taking this combination, inform your healthcare provider if you have any of the following conditions like an allergy to acetylcysteine, pyridoxine, or any other ingredient in the product, asthma or a personal history of bronchospasm (sudden tightening of the airways), active stomach ulcers or significant gastrointestinal disorders, hepatic impairment (reduced liver function), as closer medical monitoring may be required, pre-existing kidney disease requiring specialized treatment.
  • Safety and dosage requirements should be determined entirely by a healthcare professional
  • Elderly patients may require closer monitoring because age-related changes in kidney or liver function can affect treatment decisions.
  • If you are pregnant or a breastfeeding mother, use only if recommended by your doctor after thoroughly evaluating the potential benefits and risks to you and your baby.

verifiedApollotooltip
  • Nitroglycerin (a medicine used for chest pain): May increase the risk of headache, dizziness, and low blood pressure when taken with this combination. If you are taking nitroglycerin or any other nitrate medicine for a heart condition, inform your cardiologist and prescribing doctor before starting this treatment so they can assess whether any additional monitoring or precautions are needed.
  • Isosorbide dinitrate or isosorbide mononitrate (medicines used for chest pain): May further widen blood vessels and increase the likelihood of low blood pressure.
  • Carbamazepine, phenytoin, and phenobarbital (anti-seizure medicines): Long-term use may affect pyridoxine (vitamin B6) levels and potentially influence treatment outcomes.
  • Levodopa used without carbidopa (a treatment for Parkinson's disease): Pyridoxine may reduce the effectiveness of levodopa when it is taken alone. This interaction is generally not a concern with the levodopa/carbidopa combinations commonly used today.
  • Chloramphenicol (an antibiotic): May interfere with the therapeutic effects of pyridoxine.

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verifiedApollotooltip
  • No major food interactions are known. However, maintaining a consistent diet and adequate hydration is recommended. Follow any dietary advice provided by your doctor, especially if you have chronic kidney disease.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

This combination is used to support kidney function, help manage chronic kidney disease, and protect the kidneys from damage caused by contrast dyes used in medical imaging. Talk to your doctor to understand if this is suitable for your condition.
Yes, you can take this medicine with or without food, but it is important to be consistent with how you take it every day. Talk to your doctor or pharmacist for personalized advice.
Some patients may experience mild side effects such as nausea, an upset stomach, or an unpleasant taste. Serious side effects like allergic reactions are rare but require immediate medical attention. Talk to your doctor if you experience any unusual symptoms.
It works by helping the body produce natural antioxidants to neutralize harmful free radicals and by supporting the breakdown of metabolic products like homocysteine. Talk to your doctor to learn more about how this helps your specific condition.
The safety of this combination during pregnancy has not been fully established. If you are pregnant or planning a pregnancy, you should discuss the risks and benefits thoroughly before taking this medicine. Talk to your doctor for guidance.
Take the missed dose as soon as you remember, unless your next scheduled dose is near. In that case, skip the missed dose and resume your regular schedule; do not double the dose. Talk to your doctor or pharmacist if you frequently miss doses.
It is best to avoid or limit alcohol while taking this medicine, as alcohol can increase stomach irritation and add unnecessary stress to your kidneys. Talk to your doctor for specific recommendations.
You should use this medicine with caution if you have asthma, as one of the active components can occasionally trigger airway irritation. Talk to your doctor before starting this medicine to ensure it is entirely safe for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Survey No: 249, Brahmanapally(V), Hayathnagar(M),R.R.District, Hyderabad, Telangana, India 501511
Other Info - REN0760
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