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compositionComposition:RISPERIDONE-50MG
prescription
Prescription Medicine
info
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Restonorm-50 Injection 2 ml is an antipsychotic medicine used in the treatment of schizophrenia and bipolar disorder. This medication helps to improve mood, behavior, and thoughts by preventing the effects of dopamine and serotonin, two chemical messengers in the brain. Common side effects include headache, dizziness, drowsiness, fatigue, constipation, and weight gain.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

RISPERIDONE-50MG

Manufacturer/Marketer :

Alteus Biogenics Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Restonorm-50 Injection 2 ml

Restonorm-50 Injection 2 ml is a prescription injection used to treat schizophrenia and maintain mood stability in adults with bipolar I disorder. While oral Restonorm-50 Injection 2 ml is sometimes prescribed for adolescents and children, long-acting injectable formulations are primarily indicated for adults; caregivers of younger patients should consult a physician regarding age-appropriate treatment options. It belongs to a group of medicines (atypical antipsychotics) that help balance natural brain chemicals to reduce symptoms like hallucinations, confused thinking, and severe mood shifts.

Because this medicine is a long-acting injection, it is injected by a healthcare provider once every few weeks to provide continuous, steady symptom control. You do not need to worry about taking it with or without food, as it is injected directly into your body. To help achieve the best results from your treatment, it is highly beneficial to maintain a stable daily routine, get consistent sleep, and avoid stressful triggers.

While many people tolerate this medication well, some may experience mild side effects such as sleepiness, headache, or weight changes. You should contact your doctor immediately if you experience serious issues, such as high fever with muscle stiffness, severe dizziness, or uncontrolled muscle movements in your face or body.

Before starting this medicine, tell your doctor if you have a history of heart conditions, seizures, kidney disease, or liver damage. Do not take this if you have had a severe allergic reaction to this medication or any of its ingredients in the past.

This medicine can interact with other drugs that cause drowsiness, as well as certain blood pressure medications. Avoid drinking alcohol while using this medicine, as it can worsen drowsiness and dizziness. If you are pregnant, breastfeeding, or are an elderly individual, talk to your doctor or pharmacist to discuss the risks and benefits before starting treatment.

Uses of Restonorm-50 Injection 2 ml

Restonorm-50 Injection 2 ml helps manage certain mental health conditions by helping to balance brain chemicals and reduce symptoms. Your doctor may recommend it for the following conditions:

  • Schizophrenia: Restonorm-50 Injection 2 ml helps control long-term symptoms such as hallucinations, delusions, disorganized thinking, and social withdrawal.
  • Bipolar I Disorder: Restonorm-50 Injection 2 ml is used as a maintenance treatment to keep mood swings stable and prevent the return of extreme emotional highs or manic episodes.

Key Benefits

Restonorm-50 Injection 2 ml helps provide long-lasting control of symptoms associated with schizophrenia and bipolar I disorder. Key benefits include:

  • Provides long-lasting symptom control: The long-acting injection releases medicine gradually over several weeks to help maintain consistent symptom relief.
  • Reduces the need for daily tablets: Helps improve treatment adherence by reducing the need to remember a daily dose.
  • Supports clearer thinking and emotional stability: Helps reduce symptoms such as hallucinations, delusions, and mood instability, making it easier to manage daily life.
  • Helps prevent symptom recurrence: Regular treatment lowers the risk of symptom flare-ups and supports long-term recovery and stability.
Side effects of Restonorm-50 Injection 2 ml
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Restonorm-50 Injection 2 ml will be administered by the doctor.
  • Do not self-administer.

How Restonorm-50 Injection 2 ml Works

Restonorm-50 Injection 2 ml contains risperidone, an atypical antipsychotic that helps balance the activity of certain natural chemicals in the brain, particularly dopamine and serotonin. By blocking specific dopamine and serotonin receptors, it reduces overactive brain signals that can cause hallucinations, delusions, disorganised thinking, and mood disturbances. This helps improve mental clarity, stabilise mood, and reduce symptoms of schizophrenia and bipolar I disorder.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Restonorm-50 Injection 2 ml as it may cause increased dizziness. Restonorm-50 Injection 2 ml may also increase the effects of alcohol.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Restonorm-50 Injection 2 ml may pass into the breastmilk. Avoid breastfeeding while on treatment with Restonorm-50 Injection 2 ml and for at least 12 weeks after the last dose. Consult your doctor if you have any concerns.

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Driving

Unsafe

Do not drive or operate machinery as Restonorm-50 Injection 2 ml may cause tiredness, dizziness and drowsiness.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

The safety and effectiveness of Restonorm-50 Injection 2 ml in children below 18 years have not been established.

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Heart

Caution

Restonorm-50 Injection 2 ml can be used in patients with heart problems, but with caution. It may increase the risk of QT prolongation, irregular heartbeat, stroke, or heart failure, especially in older adults or those with existing cardiac conditions. ECG monitoring and a thorough review of your medications and heart history are recommended before starting treatment.

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Geriatrics

Caution

Restonorm-50 Injection 2 ml can be used in geriatric patients, but with caution due to increased risk of stroke, sedation, and heart rhythm changes. Close monitoring is essential, especially in elderly individuals with dementia or cardiovascular conditions.

What if I have taken an overdose of Restonorm-50 Injection 2 ml

Because this medication is injected by a trained healthcare professional in a clinic, an overdose is highly unlikely. However, if you suspect an overdose or experience severe sleepiness, rapid heart rate, or shaking, seek immediate emergency medical care.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of fluids, especially during hot weather or exercise, as this medicine can make it harder for your body to cool itself.
  • Eat a healthy, balanced diet: Choose fibre-rich foods and monitor your weight regularly, as this medicine may cause weight gain or changes in blood sugar and cholesterol levels. Your doctor may monitor these with regular blood tests.
  • Avoid alcohol: Do not drink alcohol while receiving this medicine, as it can increase drowsiness, dizziness, and impair your ability to think clearly.
  • Stand up slowly: Rise gradually from sitting or lying down to reduce the risk of dizziness, light-headedness, or fainting.
health query

Have a query?

How Soon It Starts Working

The time required for Restonorm-50 Injection 2 ml to start to work: The onset time of Restonorm-50 Injection 2 ml has not been clinically established. The time for which the effects of Restonorm-50 Injection 2 ml last: The duration of Restonorm-50 Injection 2 ml’s effect is clinically not established.

What if you forget to take Restonorm-50 Injection 2 ml

If you miss an appointment for your injection, contact your healthcare provider's office immediately to reschedule. Keeping a consistent injection schedule is crucial for maintaining control over your symptoms. Do not try to make up for a missed dose by getting double injections.

Storage

• Store Restonorm-50 Injection 2 ml in a refrigerator between 2°C to 8°C (36°F to 46°F).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Check the medicine before use: Your healthcare provider will inspect the vial or prefilled syringe to ensure the medicine is free of visible particles or unusual discolouration.
  • Rotate injection sites: Your healthcare provider will alternate the injection site (such as the upper arm or buttock) with each dose to help reduce skin irritation and muscle damage.
  • Avoid driving until you know its effects: Do not drive, operate machinery, or perform hazardous activities until you know how this medicine affects your alertness.
  • Protect your skin from sunlight: Wear sunscreen and protective clothing when outdoors, as this medicine may make your skin more sensitive to sunlight.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood pressure medicines: May increase the risk of low blood pressure and dizziness when combined.
  • Drowsiness-causing medicines: May severely increase sleepiness when taken with antihistamines, sleeping pills, or muscle relaxants.
  • Heart rhythm medicines: May increase the risk of irregular heartbeats when combined with certain medications.
RisperidoneSparfloxacin
Critical
RisperidoneMetoclopramide
Critical

Drug-Drug Interactions

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RisperidoneSparfloxacin
Critical
How does the drug interact with Restonorm-50 Injection 2 ml:
Coadministration of Restonorm-50 Injection 2 ml with sparfloxacin can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Sparfloxacin with Restonorm-50 Injection 2 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidoneMetoclopramide
Critical
How does the drug interact with Restonorm-50 Injection 2 ml:
Co-administration of Metoclopramide with Restonorm-50 Injection 2 ml can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Restonorm-50 Injection 2 ml with Metoclopramide is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking, jitteriness, restlessness, pacing, and foot tapping contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
RisperidoneCisapride
Critical
How does the drug interact with Restonorm-50 Injection 2 ml:
When Restonorm-50 Injection 2 ml is taken with Cisapride, it can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking cisapride together with Restonorm-50 Injection 2 ml is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
RisperidonePramipexole
Critical
How does the drug interact with Restonorm-50 Injection 2 ml:
Taking Restonorm-50 Injection 2 ml with Pramipexole may reduce the effectiveness of Pramipexole.

How to manage the interaction:
Taking Restonorm-50 Injection 2 ml with Pramipexole is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, and lightheadedness contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidoneZiprasidone
Critical
How does the drug interact with Restonorm-50 Injection 2 ml:
Co-administration of Restonorm-50 Injection 2 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Restonorm-50 Injection 2 ml with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RisperidoneHaloperidol
Severe
How does the drug interact with Restonorm-50 Injection 2 ml:
Co-administration of Restonorm-50 Injection 2 ml and Haloperidol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Co-administration of Restonorm-50 Injection 2 ml and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, loose stools, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidoneBupropion
Severe
How does the drug interact with Restonorm-50 Injection 2 ml:
Taking Bupropion with Restonorm-50 Injection 2 ml can increase the risk of seizures (fits).

How to manage the interaction:
Although taking Restonorm-50 Injection 2 ml and Bupropion together can cause an interaction, it can be taken if a doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping,. Do not stop using any medications without consulting doctor.
RisperidoneProcainamide
Severe
How does the drug interact with Restonorm-50 Injection 2 ml:
When Restonorm-50 Injection 2 ml is taken with Procainamide, it can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Co-administration of Restonorm-50 Injection 2 ml with Procainamide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
RisperidoneFosphenytoin
Severe
How does the drug interact with Restonorm-50 Injection 2 ml:
Taking Restonorm-50 Injection 2 ml with fosphenytoin may significantly reduce the blood levels of Restonorm-50 Injection 2 ml.

How to manage the interaction:
Although there is a possible interaction between Fosphenytoin and Restonorm-50 Injection 2 ml, you can take these medicines together if prescribed by a doctor. However, if you experience unusual symptoms contact a doctor immediately. Do not discontinue any medications without first consulting a doctor.
RisperidoneAmisulpride
Severe
How does the drug interact with Restonorm-50 Injection 2 ml:
Taking amisulpride with Restonorm-50 Injection 2 ml can increase the chance of abnormal heart rhythm.

How to manage the interaction:
Although taking amisulpride along with Restonorm-50 Injection 2 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol, as it can cause extreme drowsiness and increase the risk of accidental falls.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Yes. Restonorm-50 Injection 2 ml can cause movement disorders, including tardive dyskinesia, which may cause persistent or potentially irreversible involuntary movements, especially of the face, tongue, mouth, or jaw. Contact your doctor promptly if you notice unusual or repetitive movements.
Yes. Weight gain is a recognised side effect of Restonorm-50 Injection 2 ml in some people. Eating a balanced diet, staying physically active, and monitoring your weight may help manage this effect. Talk to your doctor if you notice significant weight gain or have concerns.
No, you should not stop receiving Restonorm-50 Injection 2 ml without consulting your healthcare provider. Even if you feel completely fine, stopping the medication can cause your symptoms to return. Talk to your doctor if you want to discuss your treatment plan.
It is highly recommended to avoid alcohol while receiving Restonorm-50 Injection 2 ml. Alcohol can increase the sedative effects of the medication, making you extremely sleepy, dizzy, or uncoordinated.
If you miss an appointment, contact your healthcare provider's office immediately to reschedule. Keeping a consistent injection schedule is crucial for maintaining symptom control.
Yes, this medicine can make it harder for your body to cool down. Avoid becoming overheated, drink plenty of fluids, and stay indoors during extremely hot weather.
Using Restonorm-50 Injection 2 ml during the last three months of pregnancy may cause problems in the newborn baby, such as withdrawal symptoms or breathing difficulties. Restonorm-50 Injection 2 ml can also pass into breast milk, and the effects on a breastfed infant should be considered. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor so you can discuss the potential benefits and risks and decide on the most appropriate treatment for you and your baby.
Neuroleptic Malignant Syndrome (NMS) is a rare but life-threatening reaction that may occur with antipsychotic medicines such as Restonorm-50 Injection 2 ml. Symptoms may include high fever, severe muscle stiffness, sweating, confusion, and rapid breathing. Seek immediate emergency medical care if these symptoms occur.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Alteus Biogenics Pvt. Ltd., 14-B Dover Lane, Kolkata - 700029, Wb, India.
Other Info - RES0672

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