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Retoz-MR-4 Tablet 10's

Manufacturer/Marketer

Dr. Reddy'S Laboratories Ltd

Consume Type

ORAL

In Stock

Prescription Required
Product Details

About Retoz-MR-4 Tablet 10's

Retoz-MR-4 Tablet 10's belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) indicated for the treatment of osteoarthritis, rheumatoid arthritis, gouty arthritis and ankylosing spondylitis, acute pain, chronic low back pain and muscle spasms. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Retoz-MR-4 Tablet 10's is a combination of two drugs: Etoricoxib (NSAID) and Thiocolchicoside (Muscle relaxant). Etoricoxib blocks the effect of chemical messengers, which cause pain and inflammation. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.

You are advised to take Retoz-MR-4 Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as flatulence, nausea, diarrhoea, indigestion, and swelling of hands and feet. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Retoz-MR-4 Tablet 10's may cause sleepiness and dizziness, so drive only if you are alert. Retoz-MR-4 Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Retoz-MR-4 Tablet 10's as it could lead to increased dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Retoz-MR-4 Tablet 10's

Pain, inflammation and muscle spasms

Medicinal Benefits

Retoz-MR-4 Tablet 10's is a combination of two drugs: Etoricoxib (Non-Steroidal Anti-Inflammatory Drugs) and Thiocolchicoside (Muscle relaxant). Retoz-MR-4 Tablet 10's is used for the treatment of osteoarthritis, rheumatoid arthritis, gout, ankylosing spondylitis, acute pain, chronic low back pain and muscle spasms. Etoricoxib blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, prostaglandins, which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.

Directions for Use

Take Retoz-MR-4 Tablet 10's with or after food. Swallow Retoz-MR-4 Tablet 10's as a whole with a glass of water, do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Retoz-MR-4 Tablet 10's

  • Flatulence
  • Indigestion
  • Stomach pain
  • Nausea
  • Diarrhoea
  • Swelling of hands and feet
  • Irregular heartbeat

In-Depth Precautions and Warning

Drug Warnings

Do not take Retoz-MR-4 Tablet 10's if you are allergic to any of its contents, if you have stomach ulcers, have suffered bleeding problems, clotting problems, inflammatory bowel disease, severe heart, liver or kidney problems, galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. If you have had any recent heart surgery, do not take Retoz-MR-4 Tablet 10's as it may increase the risk of fatal heart attack or stroke. Inform your doctor before taking Retoz-MR-4 Tablet 10's if you have/had stomach bleeding or ulcers, heart failure, high blood pressure, diabetes, high cholesterol, kidney or liver impairment. Consult your doctor if you are pregnant or breastfeeding. Retoz-MR-4 Tablet 10's may cause sleepiness and dizziness, so drive only if you are alert. Retoz-MR-4 Tablet 10's should not be given to children as safety have not been established. Avoid consuming alcohol along with Retoz-MR-4 Tablet 10's as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Retoz-MR-4 Tablet 10's and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Retoz-MR-4 Tablet 10's unless prescribed.

Drug Interactions

Drug-Drug Interactions: Retoz-MR-4 Tablet 10's may interact with pain killers (aspirin), bronchodilators (salbutamol), anti-depressants (lithium), cardiac glycoside (digoxin), anti-hypertensives (enalapril, ramipril, losartan, valsartan, minoxidil), antibiotics (rifampicin), blood thinners (warfarin), immunosuppressants (cyclosporine, tacrolimus), and anti-rheumatoid (methotrexate).

Drug-Food Interactions: Avoid alcohol consumption while taking Retoz-MR-4 Tablet 10's as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: Inform your doctor if you have stomach ulcers, blood disorders, stomach disorders, diabetes, high blood pressure, high cholesterol, galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption, heart, kidney or liver problems.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • SALBUTAMOL
  • LITHIUM
  • DIGOXIN
  • ENALAPRIL
  • RAMIPRIL
  • LOSARTAN
  • VALSARTAN
  • MINOXIDIL
  • RIFAMPICIN
  • WARFARIN
  • CYCLOSPORINE
  • TACROLIMUS
  • METHOTREXATE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Retoz-MR-4 Tablet 10's as it may increase drowsiness. It can also increase the risk of stomach bleeding.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Please consult your doctor before taking Retoz-MR-4 Tablet 10's; your doctor will decide whether Retoz-MR-4 Tablet 10's can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      Retoz-MR-4 Tablet 10's may cause dizziness and sleepiness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Retoz-MR-4 Tablet 10's should not be given to children as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
    • Performing yoga may also help in improving joint flexibility and pain management.
    • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
    • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
    • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
    • Acupuncture, massage and physical therapy may also be helpful.
    • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
    • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
    • Avoid smoking and alcohol consumption.

    Special Advise

    • Retoz-MR-4 Tablet 10's is not recommended for use in patients with a history of gastrointestinal ulcers or bleeding since it may worsen the patient's condition.
    • Retoz-MR-4 Tablet 10's should be used with caution in patients suffering from high blood pressure and receiving high blood pressure medicines due to the increased risk of altered blood pressure. Close monitoring of blood pressure levels is recommended for such patients.
    • Drink plenty of water and fluids. Give proper rest to your body and avoid straining of muscles or tendons.

    Other Information (RET0108)

    This item is Not Returnable.

    Expires on or after - Sep-23

    Patients Concern

    Disease/Condition Glossary

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures and arthritis.

    Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

    Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

    Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints or other body parts. Ankylosing spondylitis includes decreased flexibility which usually leads to hunched-forward posture and pain in joints.

    Gout: It is caused due to deposits of uric acid crystals in the joints, which leads to pain and inflammation in the joints. Symptoms include pain, swelling and redness in the joints, mostly the big toe.

    FAQs

    Retoz-MR-4 Tablet 10's contains Etoricoxib and Thiocolchicoside. Etoricoxib blocks the effect of chemical messengers that cause pain and inflammation. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.

    Retoz-MR-4 Tablet 10's is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, gouty arthritis and ankylosing spondylitis. Arthritis is tenderness and swelling in the joints.

    Avoid taking Retoz-MR-4 Tablet 10's if you have stomach ulcers, bleeding problems or heart problems. Talk to your doctor regarding your concerns, he/she may prescribe alternate medicine.

    Diarrhoea might be a side-effect of Retoz-MR-4 Tablet 10's. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

    Retoz-MR-4 Tablet 10's might cause swelling of feet and hands due to fluid retention (oedema). While lying down, raise your legs above by putting a pillow below them. Follow a low-salt diet as it might help in reducing fluid build-up.

    Retoz-MR-4 Tablet 10's, if taken along with birth control pills, might increase the risk of side-effects. Please consult your doctor, he/she may suggest an alternate method of contraception.

    Retoz-MR-4 Tablet 10's should be used with extreme caution in patients suffering from the infection since it may mask the symptoms of an infection, such as a fever. Frequent clinical monitoring is recommended for such patients.

    PRODUCT SUBSTITUTES

    Retoz-MR-4 Tablet 10's

    Country Of Origin

    India

    Manufacturer/Marketer address

    Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA

    Disclaimer

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    (Inclusive of all taxes)

    Provide Delivery Location

    Strip

    1

    10 Tablet in 1 Strip