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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About REX XR 250MG TABLET

REX XR 250MG TABLET is used to treat epilepsy, seizures or fits. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

REX XR 250MG TABLET contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures.

In some cases, you may experience certain common side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor about your health, allergies, and medicines to avoid side effects. Do not take REX XR 250MG TABLET if you are pregnant, as it could cause severe birth defects. Consult your doctor before taking REX XR 250MG TABLET if you are breastfeeding. Use REX XR 250MG TABLET cautiously in children under 2 years, due to higher liver risk in the first 6 months.

Uses of REX XR 250MG TABLET

REX XR 250MG TABLET is used in the treatment of seizures, bipolar disorder, and migraine. The detailed uses of REX XR 250MG TABLET are as follows:

  • Bipolar Disorder: REX XR 250MG TABLET treats manic episodes associated with bipolar disorder, stabilizes mood, and reduces symptoms.
  • Seizure Treatment: REX XR 250MG TABLET is used for treating complex partial seizures, absence seizures, and multiple seizure types by stabilizing electrical activity in the brain.
  • Migraine Prevention: REX XR 250MG TABLET prevents migraine headaches by reducing frequency and severity.

Key Benefits

  • REX XR 250MG TABLET belongs to a group of medicines called anticonvulsants or anti-epileptics.
  • REX XR 250MG TABLET is used to treat epilepsy/seizures/fits. Additionally, REX XR 250MG TABLET is also used to treat mood disorders and to prevent migraine headaches.
  • REX XR 250MG TABLET decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.
  • REX XR 250MG TABLET treats mood disorders by increasing the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect.
  • REX XR 250MG TABLET prevents migraine headaches by limiting the transmission of nerve pain.
  • REX XR 250MG TABLET is used alone or in combination to treat simple seizures, complex partial seizures, and complex absence seizures.
  • REX XR 250MG TABLET is used in combination to treat multiple seizures, such as absence seizures.

Directions for Use

  • REX XR 250MG TABLET can be taken with or without food, or as advised by the doctor.
  • It is usually taken once daily; however, your doctor may adjust the dose and frequency based on your medical condition.
  • Swallow REX XR 250MG TABLET as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

How REX XR 250MG TABLET Works

REX XR 250MG TABLET contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity, thereby helping in controlling seizures. REX XR 250MG TABLET increases the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect. Thereby, it helps treat bipolar disorder.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking REX XR 250MG TABLET, as it may cause increased dizziness.

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Pregnancy

Unsafe

REX XR 250MG TABLET belongs to pregnancy category D. Avoid taking REX XR 250MG TABLET if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Consult your doctor

REX XR 250MG TABLET may pass into breastmilk. Consult your doctor before taking REX XR 250MG TABLET if you are breastfeeding.

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Driving

Unsafe

REX XR 250MG TABLET causes dizziness and may affect thinking and motor skills. Do not drive or operate machinery until you are mentally alert.

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Liver

Unsafe

REX XR 250MG TABLET should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this. Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

REX XR 250MG TABLET can be given to children if prescribed by the doctor. The doctor will adjust the dose depending on the child's body weight. Care should be taken in children below 2 years as they are at a higher risk of liver toxicity.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Caution

REX XR 250MG TABLET can be given in elderly patients with extreme caution due to the serious adverse effects.

What if I have taken an overdose of REX XR 250MG TABLET

Please do not take more than the prescribed dose of REX XR 250MG TABLET, as it may lead to serious side effects. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Have a query?

How Soon It Starts Working

  • The time required for REX XR 250MG TABLET to start to work: The time required for REX XR 250MG TABLET to show its action is unknown.
  • The time for which the effects of REX XR 250MG TABLET last: The duration of action for REX XR 250MG TABLET is unknown.

What if you forget to take REX XR 250MG TABLET

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one and continue your regular dosage routine. Avoid taking two doses at once.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take REX XR 250MG TABLET if you are allergic to any of its contents, have/had liver problems, or urea cycle disorders.
  • Inform your doctor before taking REX XR 250MG TABLET if you have pancreatitis, blood problems, or multi-organ hypersensitivity.
  • Consult your doctor immediately if you experience suicidal tendencies while taking REX XR 250MG TABLET.
  • REX XR 250MG TABLET may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems.
  • Please do not stop taking REX XR 250MG TABLET without consulting your doctor to avoid worsening of seizures.
  • Do not take REX XR 250MG TABLET if you are pregnant, as it could cause serious birth defects.
  • If you are of child-bearing age, use effective contraception while taking REX XR 250MG TABLET.
  • Avoid driving or operating machinery, as REX XR 250MG TABLET can cause dizziness and may affect thinking and motor skills.
  • Avoid consuming alcohol along with REX XR 250MG TABLET as it could lead to increased dizziness.
  • Care should be taken while giving REX XR 250MG TABLET to children below 2 years, as there is a higher risk of liver intoxication during the first 6 months of treatment.

verifiedApollotooltip

Drug-Drug Interactions: REX XR 250MG TABLET may have interaction with pain killers (aspirin), anti-epileptics (pregabalin, topiramate, phenobarbital, primidone, phenytoin, carbamazepine, lamotrigine, felbamate, ethosuximide), anti-HIV (zidovudine), anti-depressant (duloxetine, escitalopram, amitriptyline, nortriptyline), anti-psychotic (aripiprazole, lurasidone, quetiapine), anti-anxiety (alprazolam), anti-TB (rifampicin), anti-coagulant (warfarin), antibiotics (imipenem, meropenem), and benzodiazepine (diazepam).

Drug-Food Interactions: Avoid alcohol consumption while taking REX XR 250MG TABLET, as it might cause increased dizziness and sleepiness. Alcohol intake might also provoke seizures.

Drug-Disease Interactions: REX XR 250MG TABLET may interact with disease conditions such as depression, liver disease, urea cycle disorders, suicidal tendency, HIV disease, and thrombocytopenia (low levels of platelets).

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

REX XR 250MG TABLET belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, REX XR 250MG TABLET is also used to treat manic episodes associated with bipolar disorder and to prevent migraine.

REX XR 250MG TABLET contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. REX XR 250MG TABLET increases the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect. Thereby, it helps treat bipolar disorder.

REX XR 250MG TABLET helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, which helps in blocking the nerve transmission across the brain and provides a calming effect.

REX XR 250MG TABLET limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition characterised by intense headaches.

Do not discontinue REX XR 250MG TABLET without consulting your doctor. To treat your condition effectively, continue taking REX XR 250MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking REX XR 250MG TABLET. Your doctor will reduce the dose gradually to avoid worsening of seizures.

REX XR 250MG TABLET may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with REX XR 250MG TABLET. Avoid getting pregnant while taking REX XR 250MG TABLET as it could lead to serious birth defects. Do not stop taking REX XR 250MG TABLET and consult your doctor immediately if you become pregnant.

REX XR 250MG TABLET may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking REX XR 250MG TABLET.

Topiramate (anticonvulsant) should not be taken along with REX XR 250MG TABLET as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.

It is crucial to consult with your doctor before discontinuing REX XR 250MG TABLET. Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

REX XR 250MG TABLET is also used to treat mood disorders. It treats mood disorders by increasing the amount of a chemical substance called GABA, which helps block nerve transmission across the brain and provides a calming effect.

REX XR 250MG TABLET can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, REX XR 250MG TABLET can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking REX XR 250MG TABLET, it's essential to consult with your doctor.

Yes, REX XR 250MG TABLET can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking REX XR 250MG TABLET, seeking medical attention is crucial.

Avoid consumption of alcohol while taking REX XR 250MG TABLET, as it may cause increased dizziness.

If you experience abdominal pain, nausea, and anorexia while taking REX XR 250MG TABLET, it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of REX XR 250MG TABLET can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of REX XR 250MG TABLET, please seek immediate medical attention.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - REX0041
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