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Rexotril Oral Drops is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. It also helps reduce nasal congestion and sinus pressure by shrinking swollen nasal blood vessels.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

CHLORPHENIRAMINE MALEATE-2MG/ML+PHENYLEPHRINE-5MG/ML

Manufacturer/Marketer :

Solace Biotech Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Rexotril Oral Drops

Rexotril Oral Drops is a medicine used to relieve symptoms associated with the common cold, hay fever, and upper respiratory allergies. It helps treat nasal congestion, sinus pressure, runny nose, sneezing, and itchy, watery eyes. By reducing these symptoms, it helps you breathe more easily and feel more comfortable.

For the best results, you should take this medicine exactly as directed by your doctor, typically every 4 to 6 hours as needed. You can take Rexotril Oral Drops with or without food, but taking it with a meal or a glass of milk can help prevent a mild upset stomach. To support your recovery, drink plenty of water throughout the day and use a humidifier to keep the air in your home moist.

Most people tolerate this medicine well, though you may experience mild side effects like drowsiness, dizziness, or a dry mouth. These symptoms are usually temporary and improve as your body adjusts to the medication. However, if you experience serious side effects such as a very fast heartbeat, severe nervousness, or difficulty urinating, you should stop taking the medicine and consult your doctor right away.

Before you begin taking Rexotril Oral Drops, talk to your doctor if you have certain health conditions. Do not take this medicine if you have severe high blood pressure, severe heart disease, or if you have taken a monoamine oxidase inhibitor (MAOI) within the last 14 days. It is also important to tell your healthcare provider if you have diabetes, thyroid disease, glaucoma, or difficulty urinating due to an enlarged prostate.

This medicine can interact with alcohol, sedatives, and sleep medications, which can significantly increase your drowsiness and impair your coordination. If you are pregnant, planning to become pregnant, breastfeeding, or managing the care of an elderly family member, talk to your doctor or pharmacist before using this medicine to ensure it is safe for your situation.
 

Uses of Rexotril Oral Drops

Your doctor may prescribe Rexotril Oral Drops to help manage the following conditions:

  • Common cold symptoms: It temporarily relieves runny nose, sneezing, scratchy throat, and watery eyes caused by viral infections.
  • Allergic rhinitis: It blocks the natural histamines that trigger itchy nose, sneezing, and watery eyes during allergy season.
  • Nasal congestion: It opens blocked nasal passages and relieves stuffiness caused by allergies or colds.
  • Sinus pressure: It reduces swelling in the sinuses, helping to drain trapped fluids and ease painful sinus pressure.
     

Key Benefits

Rexotril Oral Drops is used to relieve symptoms associated with the common cold, allergic rhinitis, and other upper respiratory allergies. It helps reduce nasal congestion and allergy symptoms, making breathing easier and improving overall comfort.

  • Relieves Nasal Congestion: Helps reduce swelling in the nasal passages, making it easier to breathe through the nose.
  • Controls Allergy Symptoms: Helps relieve sneezing, runny nose, itchy nose, and watery eyes caused by allergies.
  • Provides Symptomatic Relief from Colds: Helps ease common cold symptoms such as nasal blockage and excessive nasal discharge, improving daily comfort.
  • Supports Better Rest: By reducing nasal congestion and allergy symptoms, it may help improve sleep quality and reduce night-time discomfort.
  • Improves Daily Comfort: Helps reduce the impact of cold and allergy symptoms, allowing you to carry out routine activities more comfortably.
     

Directions for Use

  • Rexotril Oral Drops can be taken with or without food. However, if it causes stomach upset, it is advisable to take it with food to minimise discomfort.
  • Follow your doctor’s instructions on dosage and timing.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Rexotril Oral Drops Works

Rexotril Oral Drops contains chlorpheniramine maleate and phenylephrine. It works by combining two active ingredients that target different pathways of allergy and cold symptoms in the body. The first active component, chlorpheniramine maleate, is an antihistamine. During an allergic reaction or a cold, your body releases a natural chemical called histamine, which causes a runny nose, watery eyes, and sneezing. Chlorpheniramine maleate blocks the action of histamine, which stops these wet symptoms and dries up the nasal passages. The second active component, phenylephrine, is a decongestant. It works by acting on the receptors in the blood vessels of your nasal passages and sinuses, causing these swollen vessels to narrow. This narrowing reduces the swelling and congestion in your nose, allowing air to flow more easily and relieving pressure in your head and face. Together, these two active ingredients help relieve allergy and cold symptoms by reducing sneezing, a runny nose, watery eyes, and nasal congestion.
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Alcohol

Caution

Rexotril Oral Drops may cause excessive dizziness when taken with alcohol, so alcohol intake should be avoided.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant or planning a pregnancy. Rexotril Oral Drops should be used only if the doctor prescribes it.

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Breast Feeding

Consult your doctor

Please consult the doctor before taking the Rexotril Oral Drops if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Rexotril Oral Drops is known to cause drowsiness and sleepiness. So, drive only if you are alert.

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Liver

Caution

Rexotril Oral Drops to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Rexotril Oral Drops to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Caution

Rexotril Oral Drops is not recommended for children below the age of 4 years. For children aged four years and above, use Rexotril Oral Drops only when prescribed by a child specialist.

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Heart

Caution

Rexotril Oral Drops should be taken with caution in patients with heart conditions. Please inform your doctor about any existing heart problems before starting Rexotril Oral Drops.

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Geriatrics

Caution

Rexotril Oral Drops should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Rexotril Oral Drops.

What if I have taken an overdose of Rexotril Oral Drops

In case of an accidental overdose, seek immediate medical attention or contact a poison control centre right away. Symptoms of an overdose can include severe drowsiness, extreme dizziness, a very fast or slow heart rate, hallucinations, or seizures.

Diet & Lifestyle Advise

  • Stay Well-Hydrated: Drink plenty of water, warm fluids, or clear soups to help loosen mucus and keep your airways moist.
  • Use a Humidifier or Steam: A cool-mist humidifier or steam inhalation may help soothe irritated nasal passages and relieve congestion.
  • Use Saline Nasal Rinses: Saline nasal sprays or rinses can help clear mucus, allergens, and irritants from the nasal passages.
  • Get Adequate Rest: Ensure sufficient sleep and rest to support your body's recovery from infections or allergies.
  • Avoid Allergy Triggers: Minimise exposure to dust, pollen, pet dander, cigarette smoke, and other known triggers that may worsen your symptoms.
     
health query

Have a query?

How Soon It Starts Working

  • The time required for Rexotril Oral Drops to start to work: The time required for Rexotril Oral Drops to show its action is unknown.
  • The time for which the effects of Rexotril Oral Drops last: The duration of action for Rexotril Oral Drops is clinically unknown.

What if you forget to take Rexotril Oral Drops

If you miss a dose of Rexotril Oral Drops, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Rexotril Oral Drops at room temperature, between 15°C and 30°C (59°F and 86°F).

Drug Warnings

  • Avoid Driving Until You Know Its Effects: This medicine may cause drowsiness or dizziness. Do not drive or operate machinery until you know how it affects you.
  • Check Other Cold and Allergy Medicines: Avoid taking other products containing antihistamines or decongestants unless recommended by your doctor, as this may increase the risk of side effects.
  • Avoid Alcohol: Drinking alcohol while taking this medicine may increase drowsiness and impair alertness.
  • Consult Your Doctor if Symptoms Persist: Seek medical advice if your symptoms last longer than 7 days, worsen, or are accompanied by a high fever, persistent headache, or skin rash.
  • Use in Children Only on Medical Advice: Give this medicine to children only if recommended by a healthcare professional and follow the prescribed dose carefully.
     

verifiedApollotooltip

Rexotril Oral Drops may interact with certain medicines, affecting its effectiveness or increasing the risk of side effects.

  • Monoamine Oxidase Inhibitors (MAOIs): Do not use this medicine if you have taken an MAOI (such as phenelzine, selegiline, or tranylcypromine) in the past 14 days, as this can cause a dangerously high blood pressure crisis.
  • Sedatives and Sleep Medicines: Taking this medicine with other sedatives, tranquilisers, or sleeping pills can cause extreme drowsiness and dangerous breathing difficulties.
  • Blood Pressure Medications: It may reduce the effectiveness of certain blood pressure drugs (like beta-blockers) or cause a sudden increase in blood pressure when combined with them.
     

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verifiedApollotooltip

Certain foods and beverages may influence the safety or effectiveness of Rexotril Oral Drops during treatment.

  • Alcohol: Avoid consuming alcohol while taking this medicine, as it increases the risk of severe drowsiness, dizziness, and mental confusion.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIALLERGIC]

FAQs

Rexotril Oral Drops is used to treat symptoms caused by the common cold, flu, allergies and other breathing problems like sinusitis and bronchitis.
Rexotril Oral Drops contains Chlorpheniramine maleate and Phenylephrine. Chlorpheniramine maleate blocks histamine in the body, which is known to cause allergic symptoms. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing the stuffy nose. Together, both of them effectively reduce the symptoms of a cold and allergies.
It is not recommended to take Rexotril Oral Drops and any antidepressant medication, as it may lead to unpleasant side effects or drug interactions. Also, Rexotril Oral Drops should be taken at least 15 days after your last dose of antidepressants.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Rexotril Oral Drops and skip the missed dose. Do not take extra medicine to make up for the missed dose.
Rexotril Oral Drops is known to cause drowsiness and sleepiness. Hence, you are recommended to take it at night if you are experiencing excessive drowsiness during the day and avoid driving or doing anything that requires mental alertness.
The exact time may vary depending on the individual's condition and response to the medication. Follow your doctor's instructions carefully to achieve effective results.
Rexotril Oral Drops is not an antibiotic. It is a combination medication that typically contains ingredients like chlorpheniramine, an antiallergic, and phenylephrine, a decongestant.
Rexotril Oral Drops is an antiallergic medication typically containing ingredients like chlorpheniramine and phenylephrine. It is used to relieve cold and flu symptoms, such as fever, headache, and body pain.
Rexotril Oral Drops is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid adverse complications.
Rexotril Oral Drops can sometimes cause nausea and vomiting as side effects, though not everyone experiences them as individual responses towards medication may vary. These effects are typically mild and temporary, resolving as the body adjusts to the medication. However, if these symptoms persist or worsen, it’s essential to consult a doctor promptly to ensure the safety and well-being of the individual.
No, you should not take a higher dose of Rexotril Oral Drops than the recommended amount, as it can increase the risk of side effects and adverse health complications. Always follow the dosage your doctor prescribes or as indicated on the package. If you have any concerns about dosing, please discuss them with your doctor.
Yes, there are some contraindications related to the use of Rexotril Oral Drops, such as avoiding using Rexotril Oral Drops if you have an allergy to its ingredients, high blood pressure, severe heart disorders, overactive thyroid, kidney or liver problems, glaucoma, and urinary retention. Always consult your doctor before use.
Store Rexotril Oral Drops in a cool, dry place, and out of sunlight. Keep it out of the reach of children.
The common side effects of Rexotril Oral Drops that may occur in some individuals are drowsiness, dizziness, headache, dry mouth/nose/throat, upset stomach, constipation, or trouble sleeping. Most of these side effects of Rexotril Oral Drops do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
If you forget a dose of Rexotril Oral Drops, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double-dose to make up for a missed dose, as this may increase side effects.
If your symptoms persist or fail to improve, consult your doctor. Because the treatment process can be gradual, it may take some time to fully heal your condition. However, if you don't see improvement, your doctor may need to reassess your condition, adjust the dosage, or consider alternative treatments. Don't hesitate to consult your doctor with concerns or questions about your progress.
Don't stop taking your medication just because you're feeling better! This is a crucial moment in your recovery. Stopping too soon can lead to incomplete recovery and the return of symptoms. Instead, report your progress to your doctor and follow their advice. They will guide you on how to taper off the medication, if necessary, safely.
Yes, this medicine contains an antihistamine that commonly causes drowsiness or sleepiness. You should avoid driving, operating machinery, or performing tasks that require alertness until you know how it affects you. Talk to your doctor if the drowsiness is severe or interferes with your daily routine.
You should not take other cold, cough, or allergy medicines without checking the labels or consulting a pharmacist first. Many products contain similar ingredients, which could lead to an accidental and dangerous overdose. Talk to your doctor for guidance on combining medications.
You should consult your doctor before using this medicine if you have high blood pressure. The decongestant in this medicine can constrict blood vessels, which may raise your blood pressure or interfere with your blood pressure medications. Talk to your doctor about safer alternatives.
It is important to consult your healthcare provider before using Rexotril Oral Drops if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor will weigh the clinical benefits against any potential risks to your baby. Talk to your doctor to find the safest treatment option.
If you miss a dose, take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one. Talk to your doctor if you are unsure.
No, you should avoid alcohol while taking this medicine. Alcohol can significantly increase the drowsiness and dizziness caused by the antihistamine, which increases the risk of accidents and side effects. Talk to your doctor if you have concerns about alcohol use.
A fast, pounding, or irregular heartbeat is a serious side effect. If you experience this, stop taking the medicine immediately and seek urgent medical care. Talk to your doctor before taking this or any similar decongestant medication again.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A682543 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Chlorpheniramine Phenylephrine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A606008 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. U.S. Food and Drug Administration (FDA). 022113Orig1S000Medr [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  5. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  6. Chlorpheniramine maleate, phenylephrine HCl [Prescribing Information]. [Accessed on 18 Apr. 2019]Check here
  7. Chlorpheniramine Chlorpheniramine. 2016. [Accessed on 18 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

Scf 261, 1St Floor, Motor Market, Manimajra (Chandigarh) 160101 India
Other Info - RE92323
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