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compositionComposition:RISPERIDONE-3MG+TRIHEXYPHENIDYL-2MG
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Prescription Medicine
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RISP PLUS TABLET is used to treat schizophrenia. It contains Risperidone and Trihexyphenidyl, which decreases dopaminergic and serotonergic activity in the brain, and reduces the symptoms of schizophrenia and mood disorders. It acts on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and some side effects that arise during antipsychotic treatment. In some cases, it may cause side effects like nausea, constipation, dry mouth, weight gain, sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), and nervousness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

RISPERIDONE-3MG+TRIHEXYPHENIDYL-2MG

Manufacturer/Marketer :

D D Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About RISP PLUS TABLET

RISP PLUS TABLET is an oral prescription medication primarily used to treat schizophrenia and other long-term mental health conditions. It helps manage complex emotional and behavioural symptoms, allowing patients to think more clearly and engage with others. This combination helps manage certain physical movement symptoms, such as muscle stiffness, tremors, restlessness, and spasms, that can occur during treatment with antipsychotic medicines.

To achieve the best results, it is important to take RISP PLUS TABLET consistently at the same time every day as directed by your healthcare provider. You can take this medication with or without food, but always swallow the tablet whole with a glass of water. Combining this medication with a structured daily routine, regular sleep, and supportive therapy can greatly enhance your daily functioning.

Some people may experience mild side effects while taking RISP PLUS TABLET, such as a dry mouth, mild sleepiness, or constipation. However, you should contact your doctor immediately if you experience serious symptoms like extreme muscle stiffness, high fever, or involuntary movements of your face.

Before starting this treatment, you should discuss your medical history with your doctor, especially if you have heart problems, glaucoma, epilepsy, or liver damage. Do not take this medicine if you have a known allergy to any of its components or suffer from severe difficulty urinating.

This medicine can interact with alcohol, smoking, or other drugs that cause drowsiness by making you feel significantly more tired or dizzy. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, you should talk to your doctor or pharmacist to weigh the risks and benefits before using RISP PLUS TABLET.

Uses of RISP PLUS TABLET

RISP PLUS TABLET is used in the treatment of schizophrenia. The detailed uses of RISP PLUS TABLET are as follows:

  • Schizophrenia: RISP PLUS TABLET helps relieve core symptoms of schizophrenia, such as hearing voices, seeing things that are not there, and experiencing confused or disorganised thinking.
  • Psychotic disorders: RISP PLUS TABLET aids in stabilising mood, reducing extreme agitation, and helping patients regain a clearer connection with reality.
  • Bipolar disorder (manic episodes): The Risperidone component may help control symptoms such as excessive excitement, impulsive behaviour, irritability, and unusually elevated mood during manic episodes.
  • Autism-related irritability: The Risperidone component may help reduce severe irritability, aggression, temper outbursts, and self-injurious behaviour in certain patients with autism spectrum disorder when prescribed by a doctor.

Key Benefits

RISP PLUS TABLET helps manage symptoms of certain mental health conditions while also reducing movement-related side effects that may occur during treatment. Supporting both mental and physical well-being, it helps improve daily functioning and overall quality of life. Benefits may include:

  • Reduced distressing thoughts, hallucinations, and behavioural disturbances.
  • Improved emotional stability and ability to perform daily activities.
  • Prevention or reduction of muscle stiffness, spasms, and tremors associated with treatment.
  • Better control of body movements and improved physical comfort.
  • Improved sleep patterns and overall sense of well-being.
  • Greater confidence in social interactions and enhanced quality of life.
Side effects of Risp Plus Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.

Directions for Use

To get the full benefit of RISP PLUS TABLET, follow these step-by-step instructions:

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can change how the medicine is absorbed into your body.
  • You can take this medicine with or without food, but keeping your method consistent each day is helpful.
  • Try to take your dose at the same time every day to maintain a steady level of the medicine in your bloodstream.

Always follow your doctor's exact instructions regarding how often and when to take RISP PLUS TABLET. Do not stop taking this medication suddenly without consulting your healthcare provider first.

How RISP PLUS TABLET Works

RISP PLUS TABLET contains Risperidone and Trihexyphenidyl. • Risperidone: It helps balance certain chemical messengers in the brain, such as dopamine and serotonin. This helps reduce symptoms such as hallucinations, delusions, disturbed thoughts, and unusual behaviour. • Trihexyphenidyl: It is an anticholinergic medicine that blocks muscarinic receptors in the nervous system. This helps restore the balance between acetylcholine and dopamine activity, reducing movement-related side effects such as drug-induced Parkinsonism, muscle stiffness, tremors, restlessness, and acute dystonic reactions.
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Alcohol

Unsafe

It is unsafe to consume alcohol, since alcohol consumption with RISP PLUS TABLET may increase the risk of dizziness, fainting, or headache.

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Pregnancy

Unsafe

RISP PLUS TABLET is not safe in pregnancy because it causes miscarriage and abnormalities in the fetus.

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Breast Feeding

Caution

There is no evidence on how RISP PLUS TABLET affects breastfeeding. Please consult your doctor before taking RISP PLUS TABLET if you are breastfeeding.

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Driving

Caution

RISP PLUS TABLET is not safe during the drive because it can make you feel drowsy. So, you should do not do anything that requires concentration and attention.

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Liver

Caution

RISP PLUS TABLET to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

RISP PLUS TABLET to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

It is not recommended for children below 12 years. RISP PLUS TABLET is used to treat only above 12 years of age.

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Heart

Unsafe

RISP PLUS TABLET is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Consult your doctor

RISP PLUS TABLET is known to cause increased risk of side effects in elderly patients. Hence, please consult your physician.

What if I have taken an overdose of RISP PLUS TABLET

In case of an accidental overdose, seek emergency medical attention or contact a poison control center immediately. Symptoms of an overdose may include severe dizziness, extreme sleepiness, rapid heart rate, severe dry mouth, or difficulty breathing.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to help manage dry mouth and prevent constipation.
  • Increase dietary fiber: Eat fiber-rich foods like whole grains, vegetables, and fruits to keep your bowel movements regular.
  • Avoid overheating: This medicine can reduce your body's ability to sweat, making you more prone to heatstroke. Avoid prolonged exposure to hot weather or strenuous exercise in the heat.
  • Rise slowly: To prevent dizziness or fainting, stand up slowly from a sitting or lying position.
  • Limit caffeine: Caffeine can interfere with the calming effects of the medicine and worsen restlessness.
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Have a query?

How Soon It Starts Working

  • The time required for RISP PLUS TABLET to start to work: The time required for RISP PLUS TABLET to show its action is unknown.
  • The time for which the effects of RISP PLUS TABLET last: The duration of action for RISP PLUS TABLET is unknown.

What if you forget to take RISP PLUS TABLET

If you miss a dose of RISP PLUS TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not stop taking suddenly: Abruptly stopping RISP PLUS TABLET can cause your symptoms to return or trigger withdrawal effects. Always consult your doctor for a safe plan to gradually reduce your dose if needed.
  • Avoid driving or operating machinery: This medicine can cause drowsiness and blurred vision. Do not drive or perform hazardous tasks until you know how this medicine affects you.
  • Monitor for heat sensitivity: Be cautious during hot weather. Drink extra fluids and stay in cool environments to prevent heat-related illness.
  • Manage dry mouth safely: Suck on sugarless hard candy or chew sugar-free gum to stimulate saliva flow.
  • Watch for movement changes: Pay close attention to any unusual, involuntary movements, especially in your face or tongue, and report them to your doctor immediately.
  • Regular health checks: Your doctor may monitor your blood pressure, heart rate, body weight, blood sugar levels, cholesterol levels, and other health parameters regularly during treatment, especially during long-term use.
  • RISP PLUS TABLET should not be taken by: This medicine may not be suitable for everyone. Do not take it unless advised by your doctor if you are allergic to Risperidone, Trihexyphenidyl, or any of the ingredients in this medicine, have narrow-angle glaucoma, have severe urinary retention or significant difficulty passing urine, or have certain severe gastrointestinal blockages. Always discuss your complete medical history with your doctor before starting treatment.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Brain-calming medicines (e.g., sleeping pills, anti-anxiety medicines, strong pain relievers): Taking these alongside RISP PLUS TABLET may cause excessive drowsiness, dizziness, and impaired alertness.
  • Anticholinergic medicines and certain antihistamines: Combining these with RISP PLUS TABLET may increase the risk of dry mouth, constipation, blurred vision, and difficulty urinating.

Drug-Food Interactions

  • Alcohol: Avoid consuming alcohol while taking RISP PLUS TABLET, as it can significantly worsen side effects such as dizziness, drowsiness, and poor coordination.
  • Smoking: Smoking may affect how certain medicines are processed in the body. Inform your doctor if you smoke or if your smoking habits change during treatment, as your medicines may need to be reviewed. 

Drug-Disease Interactions:

  • Narrow-angle glaucoma: RISP PLUS TABLET may increase pressure inside the eye and worsen symptoms in people with narrow-angle glaucoma.
  • Liver disease: Patients with liver impairment may require careful monitoring, as the body's ability to process the medicine may be reduced.
  • Kidney disease: Reduced kidney function may affect the elimination of the medicine, increasing the risk of side effects.
  • Epilepsy or seizure disorders: RISP PLUS TABLET may lower the seizure threshold and increase the risk of seizures in susceptible individuals.
  • Heart rhythm disorders: This medicine should be used cautiously in patients with abnormal heart rhythms, a history of QT prolongation, or other significant heart conditions, as it may increase the risk of serious cardiac complications.
  • Enlarged prostate: RISP PLUS TABLET may worsen urinary difficulties in people with an enlarged prostate due to its anticholinergic effects.
Risperidone + TrihexyphenidylZiprasidone
Critical
Risperidone + TrihexyphenidylSparfloxacin
Critical

Drug-Drug Interactions

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Risperidone + TrihexyphenidylZiprasidone
Critical
How does the drug interact with Risp Plus Tablet:
Co-administration of Risp Plus Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Risp Plus Tablet with Ziprasidone together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Risperidone + TrihexyphenidylSparfloxacin
Critical
How does the drug interact with Risp Plus Tablet:
Co-administration of Risp Plus Tablet with Sparfloxacin can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Sparfloxacin with Risp Plus Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Risperidone + TrihexyphenidylPotassium citrate
Critical
How does the drug interact with Risp Plus Tablet:
Co-administration of Risp Plus Tablet with Potassium citrate may increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Risp Plus Tablet with Potassium citrate is not recommended as it can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, or black stools contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Risperidone + TrihexyphenidylPramipexole
Critical
How does the drug interact with Risp Plus Tablet:
Taking Risp Plus Tablet with Pramipexole may reduce the effectiveness of Pramipexole.

How to manage the interaction:
Taking Risp Plus Tablet with Pramipexole is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Risperidone + TrihexyphenidylMetoclopramide
Critical
How does the drug interact with Risp Plus Tablet:
Co-administration of Metoclopramide with Risp Plus Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Risp Plus Tablet with Metoclopramide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking, jitteriness, restlessness, pacing, and foot tapping contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
Risperidone + TrihexyphenidylPotassium chloride
Critical
How does the drug interact with Risp Plus Tablet:
Co-administration of Risp Plus Tablet with Potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Risp Plus Tablet with Potassium chloride is not recommended as it can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, or black stools contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Risperidone + TrihexyphenidylCisapride
Critical
How does the drug interact with Risp Plus Tablet:
When Risp Plus Tablet is taken with Cisapride, it can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Cisapride together with Risp Plus Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
Risperidone + TrihexyphenidylEsketamine
Severe
How does the drug interact with Risp Plus Tablet:
Taking Risp Plus Tablet with Esketamine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Risp Plus Tablet and Esketamine, can be taken together if prescribed by a doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact a doctor right away. Do not stop using any medications without talking to a doctor.
Risperidone + TrihexyphenidylPhenobarbital
Severe
How does the drug interact with Risp Plus Tablet:
Taking Risp Plus Tablet with Phenobarbital may significantly reduce the blood levels of Risp Plus Tablet.

How to manage the interaction:
Although taking Phenobarbital and Risp Plus Tablet together can result in an interaction, but can be taken if a doctor has prescribed it. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
Risperidone + TrihexyphenidylPhenytoin
Severe
How does the drug interact with Risp Plus Tablet:
Taking Risp Plus Tablet and Phenytoin may significantly reduce the blood levels of Risp Plus Tablet, which may make the medication less effective.

How to manage the interaction:
Although taking Risp Plus Tablet and Phenytoin together can cause an interaction, it can be taken if a doctor has suggested it. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

RISP PLUS TABLET is used to treat schizophrenia.
RISP PLUS TABLET is used to treat schizophrenia (A mental illness in which a person is confused). RISP PLUS TABLET is composed of two different medicines, namely, Risperidone and, Trihexyphenidyl. Risperidone is an atypical antipsychotic that acts by regulating the levels of chemical messengers (dopamine and serotonin) to enhance mood, perception and behaviour. Trihexyphenidyl is an anticholinergic agent that acts on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and some side effects that arise during antipsychotic treatment.
Stopping the RISP PLUS TABLET abruptly can cause withdrawal symptoms, and preventing it too early could make your illness come back. Please consult your doctor if you want to stop taking RISP PLUS TABLET.
No, you should not stop taking RISP PLUS TABLET suddenly, even if you feel completely better. Stopping this medicine abruptly can cause your symptoms to return or trigger uncomfortable withdrawal effects. Always talk to your doctor before making any changes to your treatment.
No, you should avoid drinking alcohol while taking RISP PLUS TABLET. Alcohol can dangerously increase drowsiness, dizziness, and coordination issues, making daily tasks unsafe. Talk to your doctor if you have questions about this.
Dry mouth is a common side effect of this medicine. You can manage it by drinking plenty of water, sucking on sugar-free hard candy, or chewing sugarless gum. If the dryness is severe or does not go away, talk to your doctor or pharmacist.
Yes, RISP PLUS TABLET can reduce your body's ability to sweat, which makes it harder for you to cool down in hot weather. To prevent overheating, stay in cool environments, drink plenty of water, and avoid intense exercise in the heat. Talk to your doctor if you feel dizzy or unusually hot.
Yes, RISP PLUS TABLET can cause drowsiness, dizziness, and blurred vision, especially when you first start taking it. You should avoid driving, riding a bicycle, or operating machinery until you know how this medication affects you. Talk to your doctor for personalized advice.
If you miss a dose of RISP PLUS TABLET, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose entirely and resume your normal schedule. Do not take two doses at the same time to make up for a missed one. Talk to your doctor or pharmacist if you are confused.
RISP PLUS TABLET should only be used during pregnancy or breastfeeding if your healthcare provider decides that the benefits outweigh the potential risks to the baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before starting this medication.
It may take several weeks of consistent use before you experience the full benefits of RISP PLUS TABLET. Your symptoms should gradually improve over this time. If you do not notice any improvement after a few weeks, do not stop taking the medicine; instead, talk to your doctor.
Yes, some people may experience increased appetite and weight gain while taking this medicine. Your doctor may recommend regular monitoring of your weight, blood sugar, and cholesterol levels during long-term treatment. Maintaining a balanced diet and regular physical activity may help reduce this risk.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

G-1/583,585,586 Sitapura Industrial Area, RIICO, Tonk Road, Jaipur (Rajasthan)-302022.
Other Info - RIS0040

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