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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Riswel Plus Tablet is used to treat schizophrenia. It contains Risperidone and Trihexyphenidyl, which decreases dopaminergic and serotonergic activity in the brain, and reduces the symptoms of schizophrenia and mood disorders. It acts on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and some side effects that arise during antipsychotic treatment. In some cases, it may cause side effects like nausea, constipation, dry mouth, weight gain, sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), and nervousness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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in last 90 days

Manufacturer/Marketer :

Sigmund Promedica

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Riswel Plus Tablet

Riswel Plus Tablet is used to treat schizophrenia. Schizophrenia is a condition that affects the way your brain processes information. It causes you to lose touch with reality. You might see, hear, or believe things that are not real. Schizophrenia is a symptom, not an illness. A mental or physical illness, substance abuse, or extreme stress or trauma can cause it.

Riswel Plus Tablet is a fixed-dose combination composed of two medicines, Risperidone and Trihexyphenidyl. Risperidone belongs to a group of drugs called atypical antipsychotics. Risperidone decreases dopaminergic and serotonergic activity in the brain, which reduces the symptoms of schizophrenia and mood disorders. Trihexyphenidyl is in a category of medicines called antimuscarinic drugs. It acts on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and some side effects that arise during antipsychotic treatment.

Riswel Plus Tablet is available in the form of oral tablets. It is dissolved in the mouth with the help of water. It can be taken two times a day, as prescribed by a doctor. Your doctor will decide the dosage based on your medical condition. In some cases, Riswel Plus Tablet can cause side effects like nausea, constipation, dry mouth, weight gain, sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), and nervousness. Most of these side effects of Riswel Plus Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Riswel Plus Tablet or any other medicines, please inform your doctor. Before taking Riswel Plus Tablet , let your doctor know if you have diabetes, heart disease, tardive dyskinesia (movement of face and jaw), or liver and kidney problems. A woman who is pregnant, thinking of being pregnant, breastfeeding, or planning to be pregnant is not allowed to take this medicine, so tell your doctor before taking this medicine. Please do not stop taking Riswel Plus Tablet on your own, as it may lead to the recurrence of symptoms or worsen the condition.

Uses of Riswel Plus Tablet

Treatment of Schizophrenia (Mental illness)

Directions for Use

Swallow Riswel Plus Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Riswel Plus Tablet is used to treat schizophrenia (A mental illness in which a person is confused). Riswel Plus Tablet is a fixed-dose combination composed of two different medicines, namely, Risperidone andTrihexyphenidyl. Risperidone is an atypical antipsychotic that acts by regulating the levels of chemical messengers (dopamine and serotonin) to enhance mood, perception and behaviour. Trihexyphenidyl is an anticholinergic agent that works on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and some side effects that arise during antipsychotic treatment.

How Riswel Plus Tablet Works

Riswel Plus Tablet is a fixed-dose combination composed of two medicines, Risperidone and Trihexyphenidyl. Risperidone belongs to a group of drugs called atypical antipsychotics. Risperidone decreases dopaminergic and serotonergic activity in the brain, which reduces the symptoms of schizophrenia and mood disorders. Trihexyphenidyl is in a category of medicines called antimuscarinic drugs. It acts on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and some side effects that arise during antipsychotic treatment.

Storage

Store in a cool and dry place away from sunlight
Side effects of Riswel Plus Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Riswel Plus Tablet

Do not take more than the prescribed dose of Riswel Plus Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Before taking Riswel Plus Tablet , inform your doctor if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Before using this Riswel Plus Tablet , inform your doctor of your medical history like, liver and kidney problems, difficulty in swallowing, family history of diabetes, eye problems, and heart problems. This drug makes you dizzy. Alcohol can make you more dizzy or drowsy. Do not drive or do anything that needs alertness until you can do it safely. A woman who is pregnant or thinking of being pregnant, breastfeeding, or trying to be pregnant is not permitted to take this medication, so inform your doctor before taking this medicine.

Drug-Drug Interactions

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RisperidoneZiprasidone
Critical
RisperidoneCisapride
Critical

Drug-Drug Interactions

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RisperidoneZiprasidone
Critical
How does the drug interact with Riswel Plus Tablet:
Co-administration of Riswel Plus Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Riswel Plus Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RisperidoneCisapride
Critical
How does the drug interact with Riswel Plus Tablet:
When Riswel Plus Tablet is taken with Cisapride, it can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking cisapride together with Riswel Plus Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
RisperidonePramipexole
Critical
How does the drug interact with Riswel Plus Tablet:
Taking Riswel Plus Tablet with Pramipexole may reduce the effectiveness of Pramipexole.

How to manage the interaction:
Taking Riswel Plus Tablet with Pramipexole is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, and lightheadedness contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidoneMetoclopramide
Critical
How does the drug interact with Riswel Plus Tablet:
Co-administration of Metoclopramide with Riswel Plus Tablet can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Riswel Plus Tablet with Metoclopramide is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking, jitteriness, restlessness, pacing, and foot tapping contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
RisperidoneSparfloxacin
Critical
How does the drug interact with Riswel Plus Tablet:
Coadministration of Riswel Plus Tablet with sparfloxacin can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Sparfloxacin with Riswel Plus Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidonePethidine
Severe
How does the drug interact with Riswel Plus Tablet:
Combining Meperidine with Riswel Plus Tablet can increase the brain related side effects.

How to manage the interaction:
Co-administration of Pethidine with Riswel Plus Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination. Do not discontinue any medications without a consulting a doctor.
RisperidonePhenobarbital
Severe
How does the drug interact with Riswel Plus Tablet:
Taking Riswel Plus Tablet with phenobarbital may significantly reduce the blood levels of Riswel Plus Tablet.

How to manage the interaction:
Although taking phenobarbital and Riswel Plus Tablet together can possibly result in an interaction, but can be taken if your doctor has prescribed it. In case you experience any unusual side effects, consult a doctor.Do not stop using any medications without a doctor's advice.
RisperidoneSotalol
Severe
How does the drug interact with Riswel Plus Tablet:
Using sotalol together with Riswel Plus Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Riswel Plus Tablet, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
RisperidoneProcainamide
Severe
How does the drug interact with Riswel Plus Tablet:
When Riswel Plus Tablet is taken with Procainamide, it can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Co-administration of Riswel Plus Tablet with Procainamide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
RisperidoneNilotinib
Severe
How does the drug interact with Riswel Plus Tablet:
Taking Riswel Plus Tablet and Nilotinib can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although there is a possible interaction between Nilotinib and Riswel Plus Tablet, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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RISPERIDONE-3MG+TRIHEXYPHENIDYL-2MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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RISPERIDONE-3MG+TRIHEXYPHENIDYL-2MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Tea

How to manage the interaction:
Consumption of tea while on the treatment with Riswel Plus Tablet can lead to increase in side effects. Limit or avoid the consumption of tea during Riswel Plus Tablet treatment.

Diet & Lifestyle Advise

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine and activities that can impact your mood. Exercise daily.

  • Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.

  • You may also practice calming techniques such as meditation and deep breathing exercises.

  • Get some normal sleep. Having enough sleep will help to stabilize your mood.

  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.

  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.

  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep a person in good health.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

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Alcohol

Unsafe

It is unsafe to consume alcohol, since alcohol consumption with Riswel Plus Tablet may increase the risk of dizziness, fainting, or headache.

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Pregnancy

Unsafe

Riswel Plus Tablet is not safe in pregnancy because it causes miscarriage and abnormalities in the fetus.

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Breast Feeding

Caution

There is no evidence on how Riswel Plus Tablet affects breastfeeding. Please consult your doctor before taking Riswel Plus Tablet if you are breastfeeding.

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Driving

Caution

Riswel Plus Tablet is not safe during the drive because it can make you feel drowsy. So, you should do not do anything that requires concentration and attention.

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Liver

Caution

Riswel Plus Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Riswel Plus Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

It is not recommended for children below 12 years. Riswel Plus Tablet is used to treat only above 12 years of age.

FAQs

Riswel Plus Tablet is used to treat schizophrenia.

Riswel Plus Tablet is used to treat schizophrenia (A mental illness in which a person is confused). Riswel Plus Tablet is composed of two different medicines, namely, Risperidone and, Trihexyphenidyl. Risperidone is an atypical antipsychotic that acts by regulating the levels of chemical messengers (dopamine and serotonin) to enhance mood, perception and behaviour. Trihexyphenidyl is an anticholinergic agent that acts on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and some side effects that arise during antipsychotic treatment.

Yes, Riswel Plus Tablet is used to help weight gain and it is not necessary for all people to experience the side effect. It is advisable to follow a regular diet and exercise to maintain a healthy weight.

Do not stop using Riswel Plus Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.

Not safe because Riswel Plus Tablet is not safe in pregnancy because it causes miscarriage and abnormalities in the fetus.

There is no evidence on how Riswel Plus Tablet affects breastfeeding. Please consult your doctor before taking Riswel Plus Tablet if you are breastfeeding.

Stopping the Riswel Plus Tablet abruptly can cause withdrawal symptoms, and preventing it too early could make your illness come back. Please consult your doctor if you want to stop taking Riswel Plus Tablet .

Country of origin

INDIA

Manufacturer/Marketer address

30-22-118, First Floor, Eluru Road,Seetharampuram,Vijayawada 520 002,Andhra Pradesh
Other Info - RIS0034

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