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compositionComposition:ROMIPLOSTIM-500MG
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Prescription Medicine
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Romy-500 Injection 1 ml belongs to the class of platelet-stimulating agents used in the treatment of idiopathic thrombocytopenic purpura. This medicine works by promoting platelet formation by activating the thrombopoietin receptor, thus helps treat the condition. Common side effects include headache, joint pain, dizziness, trouble sleeping, muscle tenderness or weakness, and indigestion.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ROMIPLOSTIM-500MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Romy-500 Injection 1 ml

Romy-500 Injection 1 ml is a prescription medicine used to treat low blood platelet counts in adults and children with chronic immune thrombocytopenia (ITP). It is prescribed when other treatments, such as corticosteroids or surgery to remove the spleen, have not worked well enough. The primary medical purpose of this treatment is to raise your platelet count to a safer level, which directly helps prevent serious bleeding episodes.

This medicine is typically given as a weekly injection, and staying consistent with your schedule is vital for keeping your platelet levels stable. Since it is given as an injection under the skin, it does not matter if you take it with or without food. Making certain lifestyle adjustments, such as avoiding high-impact physical activities, can also help protect you from bruising and bleeding while undergoing treatment.

While using Romy-500 Injection 1 ml, you may experience mild side effects like headaches or joint pain. However, it is crucial to consult your doctor immediately if you experience severe symptoms such as sudden shortness of breath, swelling in your legs, or signs of an allergic reaction.

Before starting this medicine, tell your doctor if you have a history of blood clots, bone marrow problems, or blood cancers. Do not take this if you are allergic to any of its ingredients or have a known sensitivity to proteins derived from Escherichia coli.

Using this medicine alongside blood thinners or other platelet-boosting drugs can significantly affect how it works, which is why a complete medication review is necessary. Talk to your doctor or pharmacist if you are pregnant, planning to become pregnant, breastfeeding, or if you are caring for an elderly patient who may be more sensitive to the medication's effects.

Uses of Romy-500 Injection 1 ml

Your doctor may prescribe Romy-500 Injection 1 ml to help manage the following conditions:

  • Immune Thrombocytopenia (ITP): Romy-500 Injection 1 ml helps increase the number of platelets in patients with chronic ITP, lowering the risk of bruising and severe bleeding when other therapies have failed.

Key Benefits

When used as directed as part of your treatment plan, Romy-500 Injection 1 ml may provide the following benefits:

  • Helps increase platelet counts: May raise platelet levels to a safer range in people with chronic immune thrombocytopenia (ITP).
  • Helps reduce the risk of bleeding: By increasing platelet counts, it may lower the risk of bruising and bleeding episodes associated with low platelets.
  • Supports everyday activities: As platelet counts improve, you may feel more confident carrying out daily activities with a lower risk of bleeding from minor injuries.
  • May reduce the need for other treatments: In some people, successful treatment may reduce the need for rescue medicines or platelet transfusions, as determined by their doctor.
Side effects of Romy-500 Injection 1 ml
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
  • Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
  • Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
  • Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
  • Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
  • Rest and take a break from usual activities.
  • Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
  • Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
  • Avoid strenuous activities and rest the affected area.
  • Try light stretching with gentle exercises to maintain flexibility.
  • Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Eat a balanced diet rich in fruits, vegetables, whole grains, lean protein, and healthy fats.
  • Boost fiber, fruits, vegetables, omega-3 fatty acids, and vitamin K-rich foods.
  • Limit red meat, processed foods, sugary drinks, and excessive alcohol.
  • Exercise regularly with moderate-intensity activities for healthy blood flow.
  • Stay hydrated by drinking plenty of water.
  • Quit smoking to reduce blood clot risk.
  • Practice stress-reducing techniques like yoga or meditation.
  • Maintain a healthy weight to lower cardiovascular risk.
  • Always seek guidance from a healthcare professional before implementing major changes to your diet or lifestyle.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Romy-500 Injection 1 ml will be administered by a nurse or doctor.
  • Do not self-administer.

How Romy-500 Injection 1 ml Works

Romy-500 Injection 1 ml contains romiplostim, a thrombopoietin receptor agonist. This means it works like thrombopoietin, a natural hormone that tells your bone marrow to produce platelets. After it is injected under the skin, romiplostim attaches to thrombopoietin receptors, which are proteins found on the cells in your bone marrow that develop into platelets. This stimulates the bone marrow to produce more platelets. As more platelets are produced and released into the bloodstream, platelet counts increase. Because the response varies from person to person, your doctor will monitor your platelet count regularly and adjust your dose if needed.
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Alcohol

Caution

You are recommended not to consume alcohol along with Romy-500 Injection 1 ml to avoid unpleasant side effects.

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Pregnancy

Caution

Romy-500 Injection 1 ml is not recommended in pregnancy unless indicated by the doctor. Please consult your doctor if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Breast-feeding must be avoided during treatment with Romy-500 Injection 1 ml. Please consult your doctor if you have any concerns.

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Driving

Caution

Romy-500 Injection 1 ml may cause dizziness. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Romy-500 Injection 1 ml is not recommended particularly if you have a history of chronic liver disease/conditions. Please consult your doctor if you have any concerns

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Kidney

Caution

Limited information was available for the usage of Romy-500 Injection 1 ml in patients suffering from kidney illness. Please consult your doctor if you have any concerns. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Romy-500 Injection 1 ml is not recommended for children less than one year of age.

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Heart

Caution

Romy-500 Injection 1 ml should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Romy-500 Injection 1 ml.

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Geriatrics

Caution

Romy-500 Injection 1 ml should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Romy-500 Injection 1 ml

In case of an overdose, seek immediate medical attention. An overdose can cause your platelet counts to rise to dangerously high levels, which significantly increases the risk of serious blood clots.

Diet & Lifestyle Advise

  • Reduce your risk of injury: Avoid contact sports and activities that increase the risk of falls, cuts, or bruises while your platelet count is low.
  • Protect your mouth and skin: Use a soft-bristled toothbrush and an electric razor to help reduce the risk of bleeding.
  • Check with your doctor before taking new medicines: Avoid aspirin, ibuprofen, and other non-steroidal anti-inflammatory drugs (NSAIDs) unless recommended by your doctor, as they may increase the risk of bleeding.
  • Limit alcohol: Limit or avoid alcohol, as it may increase the risk of bleeding and affect your body's ability to produce healthy blood cells.
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Have a query?

How Soon It Starts Working

The time required for Romy-500 Injection 1 ml to start to work: Romy-500 Injection 1 ml ideally shows its action within 4 to 9 days after administration. The time for which the effects of Romy-500 Injection 1 ml last: The effect of Romy-500 Injection 1 ml lasts for 28 days.

What if you forget to take Romy-500 Injection 1 ml

If you miss a scheduled injection of Romy-500 Injection 1 ml, contact your doctor or healthcare provider immediately to schedule your next dose. Do not take a double dose to make up for a missed one.

Storage

• Store Romy-500 Injection 1 ml in a refrigerator between 2°C and 8°C (36°F to 46°F).
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Keep your appointments: Attend all scheduled blood tests and follow-up visits so your doctor can monitor your platelet count and adjust your dose when needed.
  • Use the medicine exactly as prescribed: Do not change your dose or stop treatment unless your doctor tells you to, as your platelet count may fall after stopping treatment.
  • Watch for blood clots: Consult your doctor right away if you develop sudden chest pain, shortness of breath, swelling or pain in a leg, or sudden weakness or difficulty speaking.
  • Know the signs of an allergic reaction: Seek immediate medical attention if you develop a rash, swelling of your face, lips, tongue, or throat, or difficulty breathing after the injection.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (like warfarin, heparin, or aspirin): Combining these with Romy-500 Injection 1 ml can complicate your bleeding risk management. Your doctor will monitor your blood clotting closely.
  • Other medicines for ITP: Using this medicine alongside other treatments that raise platelet levels may cause your platelet counts to rise too high, increasing clotting risks.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Romy-500 Injection 1 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[PLATELET STIMULATING AGENTS]

FAQs

Romy-500 Injection 1 ml belongs to the class of platelet-stimulating agents and is primarily used to treat adults with chronic immune thrombocytopenia (ITP). It is generally recommended only for patients whose platelet counts remain low despite treatment with corticosteroids, immunoglobulins, or splenectomy, rather than as an initial treatment immediately after diagnosis.
Romy-500 Injection 1 ml contains Romiplostim, which promotes platelet formation by activating the thrombopoietin receptor. Thus Romy-500 Injection 1 ml lowers the risk of bleeding episodes in diseases like immune thrombocytopenia and other associated conditions.
Immune thrombocytopenia is an autoimmune disorder in which the immune system misidentifies platelets as foreign bodies and destroys them. It can occur due to a virus, vaccination, or certain drugs. But the origin is unknown in the majority of cases.
Idiopathic thrombocytopenic purpura is typically diagnosed with blood tests such as complete blood count and antiplatelet-antibody test.
Romy-500 Injection 1 ml is not approved to treat thrombocytopenia caused by Myelodysplastic syndrome (MDS) or any other cause of thrombocytopenia apart from chronic ITP.
Yes, some patients or their caregivers can inject Romy-500 Injection 1 ml at home. However, this is only recommended after you have received thorough, professional training from your healthcare provider. Talk to your doctor to see if home injection is appropriate for you.
If you stop taking this medicine, your platelet count is likely to drop back to its original low levels, usually within 2 weeks. This sudden drop increases your risk of bleeding, so you should never stop treatment without consulting your doctor.
No, Romy-500 Injection 1 ml does not cure chronic immune thrombocytopenia (ITP). It is a long-term treatment that helps manage the condition by keeping your platelet counts at a safer level to prevent bleeding. Talk to your doctor for more details on managing chronic ITP.
It is best to limit or avoid alcohol while using this medicine. Alcohol can affect your liver and also interfere with your blood's natural ability to clot, which can increase your overall risk of bleeding. Talk to your doctor or pharmacist about safe limits.
You will typically need weekly blood tests when you start taking this medicine so your doctor can find the correct dose. Once your platelet counts stabilise, these tests may be done less frequently, but regular monitoring is still essential.
There is limited clinical data on the safety of this medicine in pregnant women. If you are pregnant, planning to become pregnant, or breastfeeding, you must talk to your doctor to weigh the potential benefits against the risks before starting treatment.
Yes, because Romy-500 Injection 1 ml stimulates platelet production, it can sometimes cause platelet counts to rise too high, which increases the risk of blood clots. Your doctor will monitor your blood levels closely to keep your clotting risks as low as possible.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ROM0154

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