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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Fenestra Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Rosushine CV 10mg Tablet

Rosushine CV 10mg Tablet is a prescription medication used to lower the risk of heart attacks, strokes, and blood clots in individuals with existing heart disease. It combines two active medicines that work together to keep your blood vessels clear and prevent dangerous blockages. This medicine is typically prescribed after a recent heart event or procedure, such as getting a stent.

You should take Rosushine CV 10mg Tablet exactly once a day, at the same time every day, to ensure it works effectively in your body. It can be taken with or without food, though taking it with food may help prevent an upset stomach. Combining this medication with a heart-healthy diet, regular physical activity, and avoiding smoking will significantly improve your long-term results.

While taking Rosushine CV 10mg Tablet , you might experience mild side effects such as an upset stomach, mild muscle aches, or bruising more easily than usual. However, you must contact your doctor immediately if you experience severe muscle pain, dark-coloured urine, unusual or uncontrollable bleeding, or signs of liver damage such as yellowing of your skin or eyes.

Do not take this if you have active liver disease or active bleeding such as a stomach ulcer. Patients with significant kidney impairment may require special monitoring and dose adjustments, and should use this medicine only under medical supervision. Before starting Rosushine CV 10mg Tablet , tell your doctor if you have a history of liver or kidney disease, thyroid problems, or if you regularly drink alcohol.

This medicine can interact with certain pain relievers, other blood thinners, and some foods or beverages. Be sure to tell your doctor about all medicines, supplements, and dietary habits so potential interactions can be reviewed. If you are pregnant, planning to become pregnant, breastfeeding, or are over the age of 70, you must consult your doctor before using Rosushine CV 10mg Tablet , as it may not be safe for you.

Uses of Rosushine CV 10mg Tablet

Rosushine CV 10mg Tablet is prescribed to reduce the risk of serious cardiovascular events by lowering cholesterol levels and preventing harmful blood clot formation. Its uses include:

  • Prevention of heart attacks: It prevents blood clots from forming in your arteries and lowers cholesterol to keep blood flowing smoothly to your heart.
  • Prevention of stroke: By stopping blood cells from sticking together and reducing plaque buildup, it reduces the risk of a clot blocking blood flow to your brain.
  • Management of acute coronary syndrome: It helps protect patients who have recently experienced chest pain or a heart attack from having another cardiovascular event.
  • Protection after stent placement: It keeps newly placed coronary stents open and clear of blood clots.
     

Key Benefits

When taken as prescribed, Rosushine CV 10mg Tablet offers several important benefits for cardiovascular health and long-term protection, including:

  • Dual-action cardiovascular protection: Rosushine CV 10mg Tablet combines cholesterol-lowering and antiplatelet effects in a single tablet, helping protect against heart attacks and strokes.
  • Improved treatment convenience: By combining two medicines into one pill, it reduces the number of medications you need to take each day, making it easier to follow your treatment plan.
  • Reduced risk of recurrent cardiovascular events: It significantly lowers the risk of experiencing another heart attack, stroke, or other serious cardiovascular complication.
  • Support for healthy blood circulation: By helping keep blood vessels open and reducing plaque buildup, it promotes smoother blood flow throughout the body.
  • Long-term heart and vascular health: Regular use helps protect blood vessels from further damage, supporting overall cardiovascular function and physical well-being.
     

Directions for Use

To get the maximum benefit from Rosushine CV 10mg Tablet and reduce the risk of cardiovascular complications, it is important to take the medication exactly as prescribed by your doctor.

  • Swallow the tablet whole: Take the tablet with a full glass of water. Do not crush, chew, or break it unless your doctor or pharmacist advises otherwise, as this may affect how the medicine works.
  • Take it at the same time each day: Maintaining a consistent dosing schedule helps keep a steady level of the medication in your body and improves its effectiveness.
  • Can be taken with or without food: You may take Rosushine CV 10mg Tablet either on an empty stomach or with meals, according to your preference or your doctor's advice.
  • Follow your doctor's instructions carefully: Always take the medication exactly as prescribed and attend any recommended follow-up appointments.
  • Do not stop treatment suddenly: Even if you feel well, do not discontinue Rosushine CV 10mg Tablet without consulting your doctor, as stopping it abruptly may increase your risk of heart attack, stroke, or blood clot formation.
  • If you miss a dose: Take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
     

How Rosushine CV 10mg Tablet Works

How Rosushine CV 10mg Tablet Works? Rosushine CV 10mg Tablet protects your heart and blood vessels through two complementary mechanisms: Rosuvastatin belongs to a group of medicines called statins. It works in the liver by blocking an enzyme called HMG-CoA reductase, which is required for cholesterol production. This lowers levels of low-density lipoprotein (LDL or 'bad' cholesterol) and triglycerides in the blood while helping to stabilise existing fatty plaques within the arteries, reducing the risk of plaque rupture. Clopidogrel is an antiplatelet medicine that helps prevent blood platelets from sticking together and forming harmful blood clots. By reducing clot formation inside blood vessels, it helps maintain healthy blood flow and lowers the risk of heart attack and stroke. Together, these two medicines help keep arteries open, reduce plaque progression, and decrease the likelihood of dangerous cardiovascular events.
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Alcohol

Unsafe

Rosushine CV 10mg Tablet should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Rosushine CV 10mg Tablet contains Rosuvastatin, which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning for a pregnancy. Your doctor may prescribe it only in extreme cases.

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Breast Feeding

Caution

Take Rosushine CV 10mg Tablet only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Drive with caution, Rosushine CV 10mg Tablet usually causes blurry vision and may affect driving ability.

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Liver

Caution

Rosushine CV 10mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Rosushine CV 10mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Rosushine CV 10mg Tablet is not recommended for children below the age of 10 years. The safety and effectiveness of Rosushine CV 10mg Tablet have not been established in children due to limited testing of Rosushine CV 10mg Tablet on children by competent authorities worldwide.

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Heart

Safe if prescribed

Rosushine CV 10mg Tablet can be used in heart patients if prescribed by the physician to reduce the risk of heart attack and stroke. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

Rosushine CV 10mg Tablet should be used in elderly people only if prescribed by the physician.

What if I have taken an overdose of Rosushine CV 10mg Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Rosushine CV 10mg Tablet or if you experience any adverse events, please go to the emergency department of the closest hospital.

Diet & Lifestyle Advise

  • Follow a heart-healthy diet: Focus on eating foods low in saturated fats, trans fats, and cholesterol. Increase your intake of soluble fibre, fresh vegetables, fruits, and whole grains.
  • Grapefruit and grapefruit juice: Grapefruit interactions are much more significant with certain statins that are metabolised through the CYP3A4 enzyme system. Rosuvastatin is minimally affected by grapefruit in most patients. Routine avoidance is generally not required, but you should consult your doctor or pharmacist if you regularly consume grapefruit or take multiple medications.
  • Incorporate regular, gentle exercise: Aim for at least 150 minutes of moderate-intensity exercise, like brisk walking, each week, as cleared by your doctor.
  • Limit alcohol consumption: Drinking alcohol can increase your risk of liver damage and stomach bleeding while taking this medicine.
  • Avoid smoking: Smoking damages blood vessels and increases the risk of blood clots, working against the benefits of this medicine.
  • Keep scheduled blood tests: Regular lipid profile testing and other laboratory monitoring help your healthcare provider assess how well the medication is working. 
     

Have a query?

How Soon It Starts Working

The time required for Rosushine CV 10mg Tablet to start to work: Rosushine CV 10mg Tablet ideally shows its action within 1 hour after administration. The time for which the effects of Rosushine CV 10mg Tablet last: The effect of Rosushine CV 10mg Tablet lasts for 24 hours.

What if you forget to take Rosushine CV 10mg Tablet

If you miss a dose of Rosushine CV 10mg Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

Store Rosushine CV 10mg Tablet at room temperature, between 20°C to 25°C (68°F to 77°F). •Keep the medication in its original packaging or container to protect it from moisture and direct light.

Drug Warnings

  • Inform all healthcare providers: Tell any doctor, dentist, or surgeon that you are taking Rosushine CV 10mg Tablet before scheduling any medical or dental procedures, as you may need to stop taking it temporarily to prevent excess bleeding.
  • Watch for signs of bleeding: Be cautious when using sharp objects, shaving, or brushing your teeth. Use a soft-bristled toothbrush and an electric razor to minimize the risk of cuts.
  • Monitor for muscle pain: Pay close attention to any unexplained muscle aches or weakness, and report them to your doctor immediately, especially if accompanied by a fever or dark-coloured urine.
  • Avoid self-medicating for pain: Do not take nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen without asking your doctor first, as they can significantly increase your risk of stomach bleeding.
  • Do not stop taking suddenly: Stopping this medication abruptly can greatly increase your risk of a heart attack or stroke. Always consult your doctor before making any changes.
  • Individual response may vary: Some people process clopidogrel differently due to genetic factors. In certain situations, your doctor may recommend additional testing or alternative treatment options to ensure adequate protection against blood clots.
  • Attend regular follow-up appointments: Your doctor may periodically monitor your cholesterol levels, liver function, kidney function, and overall cardiovascular health to ensure the medication remains safe and effective.
  • Do not allow your medication supply to run out: Because sudden interruption of treatment may increase the risk of heart attack, stroke, or blood clot formation, refill your prescription before your current supply is exhausted. 
     

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Drug-Drug Interactions

Before taking Rosushine CV 10mg Tablet , inform your doctor about all medications, supplements, and herbal products you use, as several medicines can increase the risk of side effects or alter how this combination works.

  • Blood thinners (like warfarin): Combining Rosushine CV 10mg Tablet with anticoagulants can significantly increase the risk of bleeding and bruising.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen: Taking these medicines together may increase the risk of stomach irritation, ulcers, and gastrointestinal bleeding.
  • Certain antidepressants (such as SSRIs): These medications can further increase the risk of bleeding when used alongside clopidogrel.
  • HIV, hepatitis C, or antifungal medications: Some of these medicines can increase rosuvastatin levels in the body, raising the risk of muscle damage and other side effects.
  • Certain stomach acid medicines (such as omeprazole): Some medicines can reduce the activation of clopidogrel in the body, potentially making it less effective. Always check with your doctor before starting new medications. 

Drug-Food Interactions

Certain foods and beverages may affect the safety or effectiveness of Rosushine CV 10mg Tablet . Keep the following precautions in mind:

  • Grapefruit and grapefruit juice: Grapefruit interactions are much more significant with certain statins that are metabolised through the CYP3A4 enzyme system. Rosuvastatin is minimally affected by grapefruit in most patients. Routine avoidance is generally not required, but patients should consult their doctor or pharmacist if they regularly consume grapefruit or take multiple medications.
  • Excessive alcohol consumption: Drinking large amounts of alcohol may increase the risk of liver problems and should be avoided or limited while taking this medication.

Drug-Disease Interactions

Certain medical conditions can affect whether Rosushine CV 10mg Tablet is suitable for you. Make sure your healthcare provider is aware of your complete medical history before starting treatment.

  • Active liver disease: This medication should not be used in patients with active liver disease, as it may worsen liver function.
  • Kidney impairment: Patients with moderate to severe kidney disease may require dose adjustments and closer monitoring, particularly because rosuvastatin exposure can increase in severe renal impairment. Your doctor will determine the appropriate dose based on your kidney function.
  • Active internal bleeding: Conditions such as a bleeding stomach ulcer or other active bleeding disorders make this medication unsafe because clopidogrel reduces blood clotting.
  • Thyroid disorders: Patients with uncontrolled thyroid conditions may have a higher risk of muscle-related side effects associated with rosuvastatin.
  • History of muscle disorders: Individuals with previous muscle problems or statin-associated muscle symptoms should use this medication with caution and under medical supervision.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICOAGULANT/ANTITHROMBOTIC, ANTILIPEMICS]

FAQs

Rosushine CV 10mg Tablet is used to prevent heart attacks and strokes in the future. It lowers the raised level of cholesterol and fats (triglycerides) in the body.

Rosushine CV 10mg Tablet is composed of two medicines, namely: Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that inhibits the enzyme responsible for producing cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG), and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents the formation of clots in the blood vessels. Together, Rosushine CV 10mg Tablet reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke, and heart-related chest pain (angina).

Yes, Rosushine CV 10mg Tablet contains clopidogrel that prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots, thereby preventing heart attacks and strokes.

No, Rosushine CV 10mg Tablet contains Rosuvastatin, pregnancy category X medicine, and can harm both pregnant mother and unborn baby. Even if you are planning for pregnancy, tell your doctor that you are using Rosushine CV 10mg Tablet .

If you accidentally take an overdose of Rosushine CV 10mg Tablet , you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist, please go to the nearest clinic or hospital immediately.

It would be best if you had total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Do not drink grapefruit juice while taking Rosushine CV 10mg Tablet . Grapefruit juice may increase the blood-thinning effect of your medicine.

Yes, prolonged use of Rosushine CV 10mg Tablet may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Rosushine CV 10mg Tablet , consult your doctor about this issue.

Yes, taking Rosushine CV 10mg Tablet can increase bleeding risk as it contains aspirin and clopidogrel, which belong to a class of blood-thinning agents. Therefore, please exercise caution when shaving, cutting fingernails or toenails, or using sharp objects to prevent bleeding. Before undergoing any surgical procedure, please inform your doctor that you are taking Rosushine CV 10mg Tablet .

Consult your doctor before taking other medications while on treatment with Rosushine CV 10mg Tablet to prevent any potential interactions. Let the doctor know if you are taking antibiotics, anti-HIV drugs, antifungal, blood thinners, anti-arthritis medicines, oral contraceptives, cardiac medicines or immunosuppressants.

If you are due to undergo any surgery or dental procedure, inform the doctor that you are taking Rosushine CV 10mg Tablet . The doctor might ask you to stop Rosushine CV 10mg Tablet before surgery as it might increase the risk of bleeding.

Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation. Be cautious while using sharp objects.

It might be safe to use paracetamol while taking Rosushine CV 10mg Tablet as other painkillers may increase the risk of bleeding. However, consult the doctor before using any painkiller medicines.

Side effects of Rosushine CV 10mg Tablet include headaches, ankle swelling due to fluid retention (oedema), slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.

It is highly recommended to limit or avoid alcohol while taking this medicine. Drinking alcohol regularly can increase your risk of liver damage and stomach bleeding. Talk to your doctor about what is safe for you.

Grapefruit has a well-known interaction with certain statins that are metabolised through the CYP3A4 enzyme system. Rosuvastatin is minimally affected by grapefruit in most patients, so routine avoidance is generally not required. However, if you regularly consume grapefruit or take multiple medications, you should consult your doctor or pharmacist to determine whether any dietary restrictions apply to you.

You should avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen without consulting your healthcare provider. These pain relievers can significantly increase your risk of stomach ulcers and serious bleeding when combined with Rosushine CV 10mg Tablet . Talk to your doctor for safe pain relief alternatives.

If you develop unexplained muscle pain, tenderness, or weakness—especially if you also have a fever or dark-coloured urine—contact your doctor immediately. This could be a sign of a rare but serious muscle condition. Talk to your doctor right away.

No, Rosushine CV 10mg Tablet is not safe for use during pregnancy or while breastfeeding, as it can harm the developing baby. If you become pregnant or plan to become pregnant while taking this medicine, stop taking it and contact your healthcare provider immediately. Talk to your doctor for alternative options.

Rosushine CV 10mg Tablet can be taken at any time of day, but it is best to take it at the same time every day to maintain a consistent level of medicine in your body. Some people prefer taking it in the evening, but you should follow your doctor's recommendation. Talk to your doctor or pharmacist for guidance.

Rosushine CV 10mg Tablet is typically a long-term treatment designed to prevent serious heart events. Even if you feel perfectly healthy, you should continue taking it as prescribed. Stopping the medication early can increase your risk of heart attack or stroke. Talk to your doctor before making any changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Kuvempu Nagar, Mysore, Mysuru, Karnataka
Other Info - ROS0666
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