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compositionComposition:RIVAROXABAN-10MG
prescription
Prescription Medicine
info
Rpigat 10 mg Tablet 10's
Rpigat 10 mg Tablet 10's
Rpigat 10 mg Tablet 10's

RPIGAT 10 TABLETS is used to prevent and treat blood clots in the legs (deep vein thrombosis) and lungs (pulmonary embolism). It contains Rivaroxaban, a blood thinner that works by blocking certain clotting factors in the blood, which helps to prevent clots from forming. By doing this, it reduces the risk of serious conditions, such as stroke or blocked blood vessels. You may experience some common side effects may including bleeding, low red blood cell count (anemia), and nausea. Before taking RPIGAT 10 TABLETS , let your doctor know if you are allergic to any of its ingredients, if you are pregnant or breastfeeding, and about any other medicines you are taking or any health problems you have.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

RIVAROXABAN-10MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About RPIGAT 10 TABLETS

RPIGAT 10 TABLETS is a prescription medicine used to treat and prevent harmful blood clots. It is commonly prescribed to protect people from strokes, deep vein thrombosis (clots in the legs), and pulmonary embolisms (clots in the lungs). By keeping your blood flowing smoothly, it lowers the risk of serious medical emergencies.

For this medicine to work effectively, you must take it consistently at the same time every day. Depending on the strength of your dose, your doctor may instruct you to take it with food to ensure your body absorbs it properly, or you may be able to take it with or without food. Making simple lifestyle adjustments, such as drinking enough water and staying active, can also support your treatment.

Like all medicines, RPIGAT 10 TABLETS can cause side effects, with mild bleeding or easy bruising being the most common. However, if you experience serious symptoms like coughing up blood, severe dizziness, or bleeding that will not stop, you should contact your doctor immediately.

Do not take this if you have active, severe bleeding or severe liver damage. Before starting, it is crucial to talk to your doctor if you have kidney disease, a history of bleeding problems, or a prosthetic heart valve.

This medicine can interact with other drugs, including common pain relievers like aspirin or ibuprofen, which can increase your risk of bleeding. You should also limit alcohol consumption and consult your doctor if you are pregnant, breastfeeding, or managing health conditions as an older adult.

Uses of RPIGAT 10 TABLETS

RPIGAT 10 TABLETS may be prescribed for the following conditions related to blood clot prevention and treatment: 

  • Deep vein thrombosis (DVT): RPIGAT 10 TABLETS helps by treating existing blood clots in the deep veins of your legs and preventing new ones from forming.
  • Pulmonary embolism (PE): This medicine treats blood clots that have travelled to your lungs and reduces the chance of them happening again.
  • Stroke prevention in atrial fibrillation: For people with an irregular heartbeat, RPIGAT 10 TABLETS lowers the risk of a dangerous blood clot travelling to the brain and causing a stroke.
  • Blood clot prevention after surgery: It is used to protect you from developing blood clots in your veins after undergoing hip or knee replacement surgeries.
     

Key Benefits

RPIGAT 10 TABLETS helps prevent and treat harmful blood clots by reducing the blood's ability to clot. It lowers the risk of serious complications while supporting a safer recovery in people at increased risk of clot formation.

  • Prevents Blood Clots: Helps prevent the formation of harmful blood clots in the legs, lungs, and other parts of the body.
  • Reduces Stroke Risk: Helps lower the risk of stroke in people with conditions such as non-valvular atrial fibrillation.
  • Supports Recovery After Surgery: Helps prevent blood clots following major hip or knee replacement surgery, supporting a safer recovery.
  • Treats Existing Blood Clots: Helps prevent existing clots from becoming larger while reducing the risk of new clots forming.
  • Provides Convenient Long-Term Protection: Regular use helps reduce the risk of recurrent clotting events without the routine blood monitoring required with some older anticoagulants.
     

Directions for Use

  • RPIGAT 10 TABLETS can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow RPIGAT 10 TABLETS as a whole with a glass of water.
  • Do not chew, crush or break it.

How RPIGAT 10 TABLETS Works

RPIGAT 10 TABLETS contains rivaroxaban, which works by targeting a specific protein in your body called Factor Xa, which is essential for blood clotting. When you get a cut, your body uses these proteins to stick blood cells together to stop the bleeding. However, inside your blood vessels, unwanted clotting can block blood flow. By gently blocking the activity of Factor Xa, RPIGAT 10 TABLETS slows down your body's clotting process. This keeps your blood thin and moving smoothly through your veins and arteries, which prevents new clots from forming and stops existing clots from growing larger.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with RPIGAT 10 TABLETS as it may increase the risk of bleeding.

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Pregnancy

Consult your doctor

Tell your doctor before using RPIGAT 10 TABLETS because it may cause harmful effects. So, only use in that condition when a doctor is prescribed.

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Breast Feeding

Consult your doctor

RPIGAT 10 TABLETS may pass into breast milk. Therefore consult your doctor.

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Driving

Safe if prescribed

RPIGAT 10 TABLETS usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take RPIGAT 10 TABLETS with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take RPIGAT 10 TABLETS with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

RPIGAT 10 TABLETS is not approved for children. Therefore RPIGAT 10 TABLETS is not safe for children.

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Heart

Safe if prescribed

RPIGAT 10 TABLETS is safe for use in heart patients if adminitered by the physician

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Geriatrics

Safe if prescribed

RPIGAT 10 TABLETS can be safely used in elderly patients if prescribed by the physician. Close monitoring of the patient is needed.

What if I have taken an overdose of RPIGAT 10 TABLETS

If you take too much of this medicine, seek emergency medical care immediately. An overdose can cause severe, dangerous bleeding.

Diet & Lifestyle Advise

  • Use Gentle Oral Care Products: Brush with a soft-bristled toothbrush and use waxed dental floss to help reduce the risk of bleeding gums.
  • Shave Safely: Use an electric razor instead of a manual blade to minimise cuts and bleeding.
  • Avoid High-Risk Activities: Avoid contact sports or activities with a high risk of falls, injuries, or bruising.
  • Maintain a Balanced Diet: Eat a healthy, consistent diet. Unlike some older blood thinners, RPIGAT 10 TABLETS does not require you to avoid vitamin K-rich foods.
  • Stay Well-Hydrated: Drink adequate water throughout the day unless your doctor has advised you to restrict your fluid intake.
     

Have a query?

How Soon It Starts Working

  • The time required for RPIGAT 10 TABLETS to start to work: The time required for RPIGAT 10 TABLETS to start to work is 2 to 4 hours after administration.
  • The time for which the effects of RPIGAT 10 TABLETS last: The effect of RPIGAT 10 TABLETS lasts for 12 to 24 hours.

What if you forget to take RPIGAT 10 TABLETS

If you miss a dose, take it as soon as you remember on that same day. If it is almost time for your next scheduled dose, skip the missed one and continue with your normal routine. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure of what to do.

Storage

•Store RPIGAT 10 TABLETS at room temperature, between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from light and moisture.

Drug Warnings

  • Inform Healthcare Providers: Tell your doctor, dentist, surgeon, or other healthcare professionals that you are taking RPIGAT 10 TABLETS before any medical or dental procedure.
  • Carry Medical Identification: Wear a medical alert bracelet or carry a medical ID card stating that you are taking a blood thinner.
  • Watch for Unusual Bruising or Bleeding: Check for unexplained bruises, prolonged bleeding, blood in urine or stools, or other signs of bleeding, and seek medical advice if they occur.
  • Check Before Taking New Medicines: Consult your doctor or pharmacist before starting any prescription medicines, over-the-counter medicines, vitamins, or herbal supplements.
  • Seek Medical Attention After Head Injury: Contact your doctor immediately if you experience a fall or injury to your head, even if you feel well, as internal bleeding may occur.
     

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with RPIGAT 10 TABLETS : 

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen: May significantly increase your risk of stomach or internal bleeding.
  • Other blood thinners (like aspirin, heparin, or warfarin): Can compound the blood-thinning effect and cause dangerous bleeding.
  • Certain antifungal medicines (like ketoconazole) or antiviral medicines: Can increase the levels of RPIGAT 10 TABLETS in your body, raising the risk of side effects.

Drug-Food Interactions

Certain foods and beverages may affect the safety or effectiveness of RPIGAT 10 TABLETS , including: 

  • Grapefruit or grapefruit juice: May interfere with how your body breaks down this medicine, potentially increasing the risk of bleeding.

Drug-Disease Interactions

Inform your doctor if you have any of the following medical conditions before taking RPIGAT 10 TABLETS , as special precautions may be required:

  • Active major bleeding: Do not take this medicine if you have a condition causing active, uncontrolled bleeding.
  • Severe kidney or liver damage: May affect how your body processes and clears the medication, increasing the risk of buildup and bleeding.
     

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Habit Forming

No

Therapeutic Class

[ANTICOAGULANT/ANTITHROMBOTIC]

FAQs

RPIGAT 10 TABLETS is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation.
No, RPIGAT 10 TABLETS is not expected to cause weight gain. If you notice unexpected weight gain and think it is because of this RPIGAT 10 TABLETS , immediately consult your doctor and inform him about it.
RPIGAT 10 TABLETS has many beneficial effects, but it has the ability to make you bleed more than normal. Even with minor injuries as it decreases your ability to blood clotting. Sometimes RPIGAT 10 TABLETS may cause severe bleeding that may be dangerous and may require urgent medical care. This risk may be increased in people taking RPIGAT 10 TABLETS along with other blood thinner medicines.
While taking RPIGAT 10 TABLETS , avoid grapefruit and grapefruit juice because they may increase the level of the medicine in your body and raise the risk of bleeding. Unlike warfarin, RPIGAT 10 TABLETS is not affected by vitamin K-rich foods, so foods such as spinach, broccoli, Brussels sprouts, and other green leafy vegetables do not usually need to be restricted. If you have questions about your diet, consult your doctor or pharmacist.
It is not known that RPIGAT 10 TABLETS causes hair loss. Kindly contact your doctor.
RPIGAT 10 TABLETS is a type of medicine known as an anticoagulant. RPIGAT 10 TABLETS works by stopping a clotting factor called factor Xa from working. This thins your blood, so it takes longer to clot.
You should take RPIGAT 10 TABLETS just after a meal or snack, or as advised by the doctor. It is important to take it with food to help your body absorb the entire dose.
The side effects of RPIGAT 10 TABLETS include bleeding, nausea and anemia (lack of blood). If these side effects persist or worsen, please consult your doctor.
Yes, RPIGAT 10 TABLETS is a blood thinner. It prevents the blood from clotting inside the blood vessels and also prevents the blood clots from recurring in the blood vessels.
No. Do not stop taking RPIGAT 10 TABLETS without consulting your doctor, even if you feel better. Stopping this medicine suddenly can increase your risk of developing a blood clot or having a stroke. Continue taking it for as long as your doctor has prescribed and speak to your doctor before making any changes to your treatment.
Unlike some older blood thinners, RPIGAT 10 TABLETS does not usually require routine blood monitoring to check its thinness level. However, your doctor may perform occasional blood tests to check how your kidneys and liver are working. Talk to your doctor for personalised advice.
You should avoid taking pain relievers like ibuprofen, naproxen, or aspirin while on this medicine unless specifically directed by your doctor. These drugs can increase your risk of stomach and internal bleeding. Talk to your doctor or pharmacist about safer pain relief alternatives like acetaminophen.
For minor cuts, apply firm, direct pressure with a clean cloth for at least 5 to 10 minutes. If the bleeding does not stop after applying pressure, or if the cut is deep, seek emergency medical attention immediately. Talk to your doctor if you experience frequent nosebleeds or bruising.
It is best to limit or avoid alcohol while taking this medicine. Alcohol can increase your risk of stomach bleeding and also make you more prone to falls, which can lead to dangerous internal bleeding. Talk to your doctor about what is safe for you.
Whether you need to take RPIGAT 10 TABLETS with food depends entirely on the dose your doctor has prescribed. Some strengths must be taken with a full meal to be properly absorbed, while others can be taken with or without food. Talk to your pharmacist or check your prescription label for exact instructions.
No, this medicine is generally not recommended during pregnancy as it may cause bleeding complications for both the mother and the unborn baby. If you are planning to become pregnant or find out you are pregnant, contact your doctor immediately to discuss alternative treatments. Talk to your doctor for guidance.
Yes, but you must inform your dentist that you are taking this medicine before any procedure is performed. They will coordinate with your doctor to decide if your treatment needs to be temporarily paused or if special precautions are necessary. Talk to your doctor before making any changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 202439S031,022406S035Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.6402 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. National Health Service (NHS). Rivaroxaban - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Rivaroxaban Rivaroxaban. 2014. [Accessed on 20 Mar. 2019] Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 19 Feb. 2020] Check here
  6. Webmd.rivaroxaban. [[Accessed on 3.July].2019] Check here
  7. 2 Rajshree Singh, Prabhu D. Emmady. Rivaroxaban. StatPearls Publishing. May 2022. [Accessed on 1st June 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - RPI0002

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