Rumalef 10 Tablet 30's
MRP ₹307.5
(Inclusive of all Taxes)
₹30.8 Cashback (10%)
Extra 15% Off with Bank Offers
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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India's Most Trusted Pharmacy
Genuine Products
Composition :
LEFLUNOMIDE-10MG
Manufacturer/Marketer :
Zydus Cadila
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
About Rumalef 10 Tablet
Rumalef 10 Tablet is used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis and Psoriatic arthritis are autoimmune diseases characterised by joint inflammation, stiffness, and pain.
Rumalef 10 Tablet contains 'Leflunomide', an isoxazole immunomodulatory agent which works by suppressing the activated immune system. Thereby, it helps reduce pain, inflammation and swelling.
In some cases, Rumalef 10 Tablet may cause side effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.
Do not take Rumalef 10 Tablet if you are pregnant or planning for pregnancy, as Rumalef 10 Tablet may cause serious congenital disabilities. Rumalef 10 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Rumalef 10 Tablet may cause dizziness, so drive with caution.
Uses of Rumalef 10 Tablet
Rumalef 10 Tablet is used in the treatment of Rheumatoid arthritis and Psoriatic arthritis. The detailed uses of Rumalef 10 Tablet are as follows:
- Rheumatoid Arthritis (RA): Rumalef 10 Tablet reduces joint pain, swelling, and stiffness; slows progression of joint damage.
- Psoriatic Arthritis: Rumalef 10 Tablet eases symptoms like joint inflammation and skin lesions associated with psoriasis.
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Directions for Use
- Take Rumalef 10 Tablet with or without food as advised by your doctor.
- It is usually taken once daily; however, follow your doctor’s recommendation regarding the dosage and duration.
- Swallow Rumalef 10 Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- Rumalef 10 Tablet relieves symptoms of rheumatoid arthritis and psoriatic arthritis.
- It inhibits dihydroorotate dehydrogenase, reducing excessive immune cell activity.
- It has antiproliferative properties, helping suppress abnormal cell growth.
- Rumalef 10 Tablet reduces inflammation, redness, pain, and swelling in affected joints.
- It improves joint function and mobility, enhancing the quality of life in arthritis patients.
How Rumalef 10 Tablet Works
Rumalef 10 Tablet contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling.
Storage
• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Rumalef 10 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
- Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
- Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
- Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
- Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
- Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
- Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
- Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
- Eat protein-rich foods like fish, poultry, eggs, and legumes.
- Include foods with minerals and vitamins essential for hair health.
- Join a support group to connect with others experiencing hair loss.
- Openly discuss your feelings about hair loss.
- Consider covering up with wigs, hats, or scarves.
- Be patient and avoid seeking miracle cures.
Dealing with Medication-Induced Headache:
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
- Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
- Protect your skin from extreme heat and try to apply wet compresses.
- Soak in the cool bath, which gives a soothing impact to the affected area.
What if I have taken an overdose of Rumalef 10 Tablet
Do not take more than the prescribed dose of Rumalef 10 Tablet as it may cause an overdose. The symptoms of overdose include weakness, stomach pain, diarrhoea, pale skin, extreme tiredness, shortness of breath and fast heartbeat. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.
Drug Warnings
- Do not take Rumalef 10 Tablet if you are allergic to leflunomide, have severe liver or kidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections.
- Rumalef 10 Tablet is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age.
- Talk to your doctor before taking Rumalef 10 Tablet if you have/had serious infections like interstitial lung disease (inflammation of the lungs), tuberculosis (TB), or pneumonia.
- Rumalef 10 Tablet may cause dizziness, so drive with caution.
- Rumalef 10 Tablet may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
- Inform your doctor if you are taking any other medicines, including supplements and herbal products.
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Rumalef 10 Tablet:
When erlotinib is taken with Rumalef 10 Tablet, it increases the risk of causing liver problems.
How to manage the interaction:
Although there is a possible interaction between Erlotinib and Rumalef 10 Tablet, you can take these medicines together if advised by your doctor. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, liver damage, or bleeding, it's important to contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
When erlotinib is taken with Rumalef 10 Tablet, it increases the risk of causing liver problems.
How to manage the interaction:
Although there is a possible interaction between Erlotinib and Rumalef 10 Tablet, you can take these medicines together if advised by your doctor. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, liver damage, or bleeding, it's important to contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Rumalef 10 Tablet:
Combining Lamivudine with Rumalef 10 Tablet can increase the risk and severity of muscle problems.
How to manage the interaction:
Although there is a possible interaction between Lamivudine and Rumalef 10 Tablet, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms it's important to contact your doctor right away: fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine or bleeding. Do not stop using any medications without talking to your doctor.
Combining Lamivudine with Rumalef 10 Tablet can increase the risk and severity of muscle problems.
How to manage the interaction:
Although there is a possible interaction between Lamivudine and Rumalef 10 Tablet, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms it's important to contact your doctor right away: fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine or bleeding. Do not stop using any medications without talking to your doctor.
Severe
How does the drug interact with Rumalef 10 Tablet:
Coadministration of Rumalef 10 Tablet and bortezomib may increase the risk of infections.
How to manage the interaction:
Although using Bortezomib and Rumalef 10 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, red or irritated skin, or burning during urination. Do not stop taking any medications without consulting a doctor.
Coadministration of Rumalef 10 Tablet and bortezomib may increase the risk of infections.
How to manage the interaction:
Although using Bortezomib and Rumalef 10 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, red or irritated skin, or burning during urination. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Rumalef 10 Tablet:
Taking Cyclophosphamide with Rumalef 10 Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Rumalef 10 Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Taking Cyclophosphamide with Rumalef 10 Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Rumalef 10 Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Rumalef 10 Tablet:
Coadministration of Piroxicam and Rumalef 10 Tablet can increase the risk of liver damage.
How to manage the interaction:
Although there is a possible interaction between Rumalef 10 Tablet and Piroxicam, you can take these medicines together if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of hunger, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Piroxicam and Rumalef 10 Tablet can increase the risk of liver damage.
How to manage the interaction:
Although there is a possible interaction between Rumalef 10 Tablet and Piroxicam, you can take these medicines together if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of hunger, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
LeflunomideAlefacept
Severe
How does the drug interact with Rumalef 10 Tablet:
Coadministration of Rumalef 10 Tablet together with alefacept may raise the risk of severe infections.
How to manage the interaction:
Although there is an interaction between alefacept and Rumalef 10 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
Coadministration of Rumalef 10 Tablet together with alefacept may raise the risk of severe infections.
How to manage the interaction:
Although there is an interaction between alefacept and Rumalef 10 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rumalef 10 Tablet:
Taking propylthiouracil with Rumalef 10 Tablet can increase the risk of liver problems.
How to manage the interaction:
Co-administration of Rumalef 10 Tablet with Propylthiouracil can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain, unusual bleeding, itching, fatigue, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking propylthiouracil with Rumalef 10 Tablet can increase the risk of liver problems.
How to manage the interaction:
Co-administration of Rumalef 10 Tablet with Propylthiouracil can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain, unusual bleeding, itching, fatigue, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Rumalef 10 Tablet:
Combining Clofarabine with Rumalef 10 Tablet can increase the risk of negative side effects.
How to manage the interaction:
Although taking Rumalef 10 Tablet and Clofarabine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these symptoms - such as fever, diarrhea, or muscle aches - contact your doctor immediately. Do not stop using any medications without talking to your doctor.
Combining Clofarabine with Rumalef 10 Tablet can increase the risk of negative side effects.
How to manage the interaction:
Although taking Rumalef 10 Tablet and Clofarabine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these symptoms - such as fever, diarrhea, or muscle aches - contact your doctor immediately. Do not stop using any medications without talking to your doctor.
Severe
How does the drug interact with Rumalef 10 Tablet:
Taking atomoxetine with Rumalef 10 Tablet can cause liver problems.
How to manage the interaction:
Although there is an interaction between atomoxetine and Rumalef 10 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Taking atomoxetine with Rumalef 10 Tablet can cause liver problems.
How to manage the interaction:
Although there is an interaction between atomoxetine and Rumalef 10 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Rumalef 10 Tablet:
Coadministration of nicotinamide with Rumalef 10 Tablet can increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between nicotinamide and Rumalef 10 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of nicotinamide with Rumalef 10 Tablet can increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between nicotinamide and Rumalef 10 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
- Performing yoga may also help in improving joint flexibility and pain management.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Acupuncture, massage and physical therapy may also be helpful.
- Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
- Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
- Avoid smoking and alcohol consumption.
Habit Forming
No
Therapeutic Class
ANTIRHEUMATICS
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Alcohol
Unsafe
You are recommended to avoid alcohol consumption while taking Rumalef 10 Tablet . Alcohol intake, along with Rumalef 10 Tablet , may cause liver disease.
Pregnancy
Unsafe
It is not recommended to take Rumalef 10 Tablet while you are pregnant. Rumalef 10 Tablet may cause serious birth defects.
Breast Feeding
Unsafe
It is not recommended to take Rumalef 10 Tablet while you are breastfeeding. Rumalef 10 Tablet passes into breast milk.
Driving
Caution
Rumalef 10 Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.
Liver
Consult your doctor
Please consult your doctor if you have liver impairment before taking Rumalef 10 Tablet .
Kidney
Consult your doctor
Please consult your doctor if you have kidney impairment before taking Rumalef 10 Tablet .
Children
Unsafe
Rumalef 10 Tablet is not approved for children under the age of 18 years.
Heart
Avoid taking Rumalef 10 Tablet if you have any cardiac problems. If prescried, caution should be exercised while taking Rumalef 10 Tablet .
Geriatrics
Consult your doctor
Please consult a doctor before giving Rumalef 10 Tablet to geriatric patients.
FAQs
Country of origin
India
Manufacturer/Marketer address
Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - RUM0014
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