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  1. Home
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  3. Rytstat 50 mg Tablet 6's

Prescription drug
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Rytstat 50 mg Tablet 6's, Pack of 6
Rytstat 50 mg Tablet 6's, Pack of 6
Rytstat 50 mg Tablet 6's, Pack of 6
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Extra 15% Off with Bank Offers

Composition :

DESIDUSTAT-50MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rytstat 50 mg Tablet

Rytstat 50 mg Tablet is used to treat anaemia associated with chronic kidney disease (CKD) in patients receiving dialysis or not. Anaemia is a condition that arises when your blood produces fewer healthy red blood cells than usual.

Rytstat 50 mg Tablet contains Desidustat, which works by stimulating the body's natural production of erythropoietin; this, in turn, promotes the production of red blood cells.

In some cases, Rytstat 50 mg Tablet may cause side effects, including fever, vomiting, abnormal weakness, and peripheral oedema (swelling of your lower legs or hands). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Before taking Rytstat 50 mg Tablet, let your doctor know about all your medical conditions, sensitivities, and all medications you are using, including supplements and herbal products. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Rytstat 50 mg Tablet

Rytstat 50 mg Tablet is used in the treatment of Anaemia induced by chronic kidney disease (CKD). The detailed uses of Rytstat 50 mg Tablet are as follows:

  • Treatment of Anaemia in Chronic Kidney Disease (CKD): Rytstat 50 mg Tablet is effective in managing anaemia in both dialysis and non-dialysis patients with CKD, helping to improve haemoglobin levels and reduce symptoms.
  • Stimulating Erythropoiesis: Rytstat 50 mg Tablet helps in the production of red blood cells, thereby improving haemoglobin levels and reducing the need for blood transfusions.
  • Improving Iron Metabolism: Rytstat 50 mg Tablet also enhances iron metabolism, which is essential for the production of healthy red blood cells.

Have a query?

Directions for Use

  • Rytstat 50 mg Tablet can be taken on an empty stomach, at least 1 hour before or 2 hours after meals.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow it as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Rytstat 50 mg Tablet contains Desidustat, which stimulates the body's natural erythropoietic response by increasing endogenous production of erythropoietin, thereby improving haemoglobin levels and reducing anaemia-related symptoms.
  • It helps raise haemoglobin concentration and hematocrit, improving oxygen-carrying capacity and enhancing patient quality of life.
  • It offers a novel and convenient approach to managing anaemia in CKD, supporting better patient adherence and outcomes.

How Rytstat 50 mg Tablet Works

Rytstat 50 mg Tablet contains Desidustat, which works by stimulating the body's natural production of erythropoietin; this, in turn, promotes the production of red blood cells.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Rytstat 50 mg Tablet
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
  • Avoid diet rich in salt and carbohydrates
  • Drink plenty of water and stay hydrated.
  • Exercise regularly and maintain a healthy lifestyle.
  • Take potassium rich foods like potatoes, spinach, tomatoes, sea food and dairy products.
  • Take beverages containing caffeine like coffee and tea.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
  • Consume calcium-rich dairy products for bone health.
  • Eat green and leafy vegetables for essential nutrients.
  • Include lean protein sources like eggs and whole grains.
  • Use herbs and spices for added flavor and nutrition.
  • Choose fortified foods for extra nutritional benefits.
  • Get plenty of sleep for overall health and well-being.

What if I have taken an overdose of Rytstat 50 mg Tablet

No specific side effects have been reported under these circumstances. If you take more than the prescribed dose, please go to the emergency department of the closest hospital immediately.

Drug Warnings

  • Do not take Rytstat 50 mg Tablet if you are allergic to any of its components.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Women of child-bearing potential must use appropriate contraception during treatment.
  • Inform your doctor if you have any other medical conditions or if you are taking other medicines to prevent potential interactions.

Drug-Drug Interactions

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DasatinibHalofantrine
Critical
DasatinibPimozide
Critical

Drug-Drug Interactions

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DasatinibHalofantrine
Critical
How does the drug interact with Rytstat 50 mg Tablet:
Using Halofantrine together with Rytstat 50 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Rytstat 50 mg Tablet with Halofantrine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without doctor's advice.
DasatinibPimozide
Critical
How does the drug interact with Rytstat 50 mg Tablet:
Using Pimozide together with Rytstat 50 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Rytstat 50 mg Tablet with Pimozide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibDronedarone
Critical
How does the drug interact with Rytstat 50 mg Tablet:
Using dronedarone together with Rytstat 50 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Rytstat 50 mg Tablet with Dronedarone is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.
DasatinibMesoridazine
Critical
How does the drug interact with Rytstat 50 mg Tablet:
Using Mesoridazine together with Rytstat 50 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Rytstat 50 mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibAmiodarone
Severe
How does the drug interact with Rytstat 50 mg Tablet:
Co-administration of Rytstat 50 mg Tablet with Amiodarone may increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although taking Rytstat 50 mg Tablet with Amiodarone may cause an interaction, it is safe if a doctor has prescribed it. If you develop dizziness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor. Do not stop taking any medications without visiting a doctor.
DasatinibFenoprofen
Severe
How does the drug interact with Rytstat 50 mg Tablet:
Using Rytstat 50 mg Tablet together with Fenoprofen may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Rytstat 50 mg Tablet and Fenoprofen, you can take these medicines together if prescribed by a doctor. If you notice any of these symptoms - like bruising, feeling dizzy or lightheaded, having red or black stools, severe headaches, weakness, or vomiting - make sure to contact a doctor. Do not discontinue any medications without consulting a doctor.
DasatinibIndometacin
Severe
How does the drug interact with Rytstat 50 mg Tablet:
Using Rytstat 50 mg Tablet together with Indometacin may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Indometacin with Rytstat 50 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience bruising, dizziness, red or black, tarry stools, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
DasatinibNatalizumab
Severe
How does the drug interact with Rytstat 50 mg Tablet:
Using Natalizumab together with Rytstat 50 mg Tablet may increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Natalizumab and Rytstat 50 mg Tablet, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms - fever, muscle aches, difficulty breathing, pain or burning while urinating - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
DasatinibRanitidine bismuth citrate
Severe
How does the drug interact with Rytstat 50 mg Tablet:
Using Rytstat 50 mg Tablet together with Ranitidine bismuth citrate may interfere with the absorption of Rytstat 50 mg Tablet.

How to manage the interaction:
Taking Ranitidine bismuth citrate with Rytstat 50 mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. Doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
DasatinibCrizotinib
Severe
How does the drug interact with Rytstat 50 mg Tablet:
Using Crizotinib together with Rytstat 50 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Crizotinib with Rytstat 50 mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, fainting, breathlessness, or heart palpitations. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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Grapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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Grapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice can significantly increase the blood levels and effects of Rytstat 50 mg Tablet. Avoid consumption of Grapefruit juice with Rytstat 50 mg Tablet. However, contact a doctor if you experience dizziness, shortness of breath, heart palpitations, pain, or burning during urination.

Diet & Lifestyle Advise

  • Follow a well-balanced diet and do regular physical exercise.
  • People with kidney problems are advised to limit sodium in their diet, including added salt.
  • Olive oil is a healthy source of fat and phosphorus-free, making it a great option for people with kidney disease.
  • Bulgur is a whole-grain wheat product that makes a terrific, kidney-friendly alternative to other whole grains high in phosphorus and potassium.
  • Blueberries are packed with nutrients and are one of the best sources of antioxidants you can eat.
  • Include dark-green leafy vegetables, cereals, bread, meat, pulses (beans, peas and lentils), and dried fruit like apricots, prunes and raisins in your diet.
  • Increase your intake of fruits in your diet, especially fruits rich in iron, like pomegranate and citrus fruits.
  • Limit the consumption of tea, coffee, milk, dairy, and foods with high levels of phytic acids, such as whole-grain cereals.
  • Limit junk food items from outside and stick to freshly prepared home-cooked meals.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Rytstat 50 mg Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Avoid consumption of alcohol with Rytstat 50 mg Tablet as it may cause serious side effects.

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Pregnancy

Caution

There is no information available about the use of Rytstat 50 mg Tablet during pregnancy. Consult your doctor if you are pregnant or suspect you are pregnant.

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Breast Feeding

Caution

Rytstat 50 mg Tablet is not recommended during breastfeeding as it is unknown if desidustat passes into breastmilk.

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Driving

Safe

Rytstat 50 mg Tablet does not alter your ability to drive or use machinery.

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Liver

Consult your doctor

There is no information available about the use of Rytstat 50 mg Tablet in patients with liver impairment. Consult your doctor if you have liver problems.

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Kidney

Safe if prescribed

Rytstat 50 mg Tablet is prescribed for the treatment of anaemia induced by chronic kidney disease. Your doctor will decide the dose of this medicine based on your disease condition.

bannner image

Children

Caution

The safety and efficacy of Rytstat 50 mg Tablet in children was not established.

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Heart

Please consult your doctor before receiving Rytstat 50 mg Tablet if you have pre-existing heart problems. Your doctor will prescribe Rytstat 50 mg Tablet if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Rytstat 50 mg Tablet to geriatric patients. Your doctor will prescribe Rytstat 50 mg Tablet if the benefits outweigh the risks.

FAQs

Rytstat 50 mg Tablet is used to treat anaemia associated with chronic kidney disease (CKD).

Rytstat 50 mg Tablet contains Desidustat, which works by stimulating the body's natural production of erythropoietin; this, in turn, promotes the production of red blood cells.

People who do not acquire enough iron, vitamin B12, and folic acid to create healthy red blood cells are more likely to develop anaemia. Excessive alcohol use increases your risk of anaemia.

Eating foods like red meat, beans, and peas can be beneficial if one has vitamin deficiency anaemia. In addition, items like dry fruits, dark green leafy vegetables, and seafood can supply the necessary vitamins and minerals.

Yes, Rytstat 50 mg Tablet may cause Peripheral oedema (swelling of your lower legs or hands). If symptoms persist or bother you, reach out to the doctor immediately.

The side effects of Rytstat 50 mg Tablet include vomiting, fever, abnormal physical weakness and peripheral oedema (swelling of your lower legs or hands). If these side effects persist or worsen, please consult your doctor.

Chronic kidney disease, or CKD, is an irreversible and progressive loss of kidney function. As a result, the body retains excess waste or toxins which may lead to other health problems. The symptoms include swelling of legs, shortness of breath, swelling around the eyes, weight loss, fatigue (overtiredness), decreased urine output, nausea or vomiting, especially in the morning or after eating, loss of appetite and trouble sleeping.

Your doctor may recommend a blood test to determine whether you have kidney disease. The test measures the amount of creatinine (waste product) in your blood. The doctor will use the blood test results, your gender, age, weight, and ethnic group to calculate how many millilitres of waste your kidneys should be able to filter in a minute. This calculation is known as your eGFR or estimated glomerular filtration rate. Healthy kidneys should be able to filter more than 90 mL/min. If your rate is lower than this, you may have kidney disease.

If you have diabetes, high blood pressure, heart disease, or a family history of kidney failure, you are more likely to develop kidney disease. If you have risk factors, it is advisable to get examined for kidney disease and protect your kidneys by changing your diet, lifestyle and controlling your blood glucose levels and blood pressure.

Your kidneys make erythropoietin (EPO), an important hormone that instructs your body to produce red blood cells. Kidneys fail to make enough EPO in case of kidney disease. Low EPO levels decreases red blood cell count resulting in anemia.

The risk for anemia increases when kidney disease worsens. People with CKD who also have diabetes are at a greater risk for developing anemia, likely to develop anemia earlier, and often have more severe anemia than those without diabetes. In addition, anemia with CKD is more common in people aged over 60 years.

Some of the symptoms of anemia in patients with CKD include dizziness, pale skin, fatigue (overtiredness), headache, shortness of breath, body pain, and irregular or fast heartbeats.

In patients with CKD, severe anemia can increase the risk of heart problems and strokes due to low oxygen levels in the body, which results from the decreasing level of red blood cells in the body.

Country of origin

India

Manufacturer/Marketer address

Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Other Info - RYT0030

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 16, 2025 | 7:19 AM IST

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Reference

  1. https://http://oxemia.com/images/desidustat_summary_of_product_information.pdf
  2. https://go.drugbank.com/drugs/DB16135
  3. https://pubmed.ncbi.nlm.nih.gov/35834123/
  4. https://zyduslife.com/public/pdf/pressrelease/Zydus-announces-Phase-IV-DREAM-CKD-trial-to-generate-Real-World-Evidence-of-Desidustat.pdf
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281218/

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