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compositionComposition:SULFASALAZINE-500MG
prescription
Prescription Medicine
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Saaz Tablet is used to treat bowel diseases (ulcerative colitis, Crohn's disease), skin-related problems (psoriasis), and chronic joint diseases (rheumatoid arthritis, ankylosing spondylitis) in children and adults. It contains Sulfasalazine, which works as an inflammation reducer by acting locally, inhibiting the formation of a chemical known as prostaglandins, that control pain and inflammation. Thus, it helps reduce the inflammation of the intestine, skin, and joints. In some cases, you may experience a sore throat, a fever, unexplained bruising, or ringing in your ears (tinnitus). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SULFASALAZINE-500MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Saaz Tablet

Saaz Tablet is a prescription medicine used to reduce inflammation and help manage certain chronic inflammatory conditions. It is commonly prescribed for inflammatory bowel diseases such as ulcerative colitis and for inflammatory joint conditions such as rheumatoid arthritis. By helping control inflammation, this medicine can reduce symptoms and support long-term disease management.

Take Saaz Tablet exactly as prescribed by your doctor. It is usually taken with food and a full glass of water to help reduce stomach discomfort. Taking the medicine regularly, even when you feel well, helps maintain symptom control and reduce the risk of disease flare-ups.

Some people may experience mild side effects such as nausea, headache, loss of appetite, or stomach discomfort when starting treatment. These effects are often temporary and may improve as your body adjusts to the medicine. However, contact your doctor promptly if you develop severe skin reactions, unusual bruising or bleeding, yellowing of the skin or eyes, persistent fever, or signs of an allergic reaction.

Before taking Saaz Tablet , inform your doctor if you have kidney disease, liver disease, asthma, blood disorders, or a history of allergies to sulfonamides or aspirin-containing medicines. This medicine may not be suitable for people with certain intestinal or urinary tract blockages.

Limit alcohol consumption while taking this medicine, as excessive alcohol use may increase the risk of liver-related side effects. Tell your doctor if you are pregnant, planning to become pregnant, breastfeeding, or trying to conceive so they can determine whether this medicine is appropriate for you. 

Uses of Saaz Tablet

Saaz Tablet is used to treat inflammatory bowel diseases and inflammatory joint conditions. The detailed uses of Saaz Tablet are as follows:

  • Ulcerative Colitis: Helps reduce inflammation in the lining of the large intestine and supports both symptom control and maintenance of remission.
  • Rheumatoid Arthritis: Helps reduce joint pain, swelling, stiffness, and inflammation in people with rheumatoid arthritis.
  • Crohn's Disease: May be used in selected patients with mild-to-moderate inflammatory bowel disease, particularly when inflammation affects the colon.
  • Other Inflammatory Conditions: In certain situations, doctors may prescribe this medicine for other inflammatory disorders based on individual patient needs.

Key Benefits

Saaz Tablet helps control chronic inflammation and supports long-term management of inflammatory conditions. Regular treatment may improve comfort, mobility, and overall quality of life.

  • Improved Joint Comfort: Helps reduce pain, stiffness, and swelling associated with inflammatory arthritis.
  • Better Physical Function: Supports improved movement and daily activities by helping control inflammation.
  • Supports Digestive Health: Helps reduce symptoms such as abdominal discomfort, diarrhoea, and rectal bleeding associated with ulcerative colitis.
  • Helps Prevent Disease Flare-Ups: Consistent use may reduce the frequency and severity of symptom recurrence in chronic inflammatory conditions.
Side effects of Saaz Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Boost your immunity by including immune-rich foods in your diet, and always remember to stay hydrated.
  • Get sufficient sleep and manage stress, which helps improve white blood cell count.
  • Consult your doctor for an effective treatment to improve immunity and get regular body check-ups to monitor changes in the count.
  • Exercise regularly to lower stress and improve stamina and immunity.
  • Smoking can affect immunity. It is advisable to avoid such a habit.
  • Practice good hygiene practices to lower the chances of falling sick.

Directions for Use

To get the full benefit of Saaz Tablet and minimise side effects, follow these simple guidelines:

  • Take the tablet orally with food and a full glass of water.
  • Swallow the tablet whole. Do not crush, chew, or break it unless specifically instructed by your doctor.
  • Drink plenty of fluids throughout the day to help support healthy kidney function.
  • Take the medicine at the same time each day to maintain consistent levels in your body.
  • Continue taking the medicine regularly unless your doctor advises otherwise.
  • Always follow your doctor's exact instructions regarding dosage and duration of treatment.
     

How Saaz Tablet Works

Saaz Tablet contains sulfasalazine. After it reaches the intestine, natural bacteria break the medicine into active components that help reduce inflammation. Reduces Inflammation in the Bowel: One component acts directly within the intestine to help decrease inflammation and tissue irritation. Modulates Immune Activity: The medicine helps regulate inflammatory processes that contribute to joint swelling and stiffness in rheumatoid arthritis. Supports Long-Term Disease Control: By reducing inflammation in affected tissues, the medicine helps improve symptoms and may slow disease progression in certain conditions. Through these actions, Saaz Tablet helps manage symptoms and support long-term control of inflammatory diseases.
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Alcohol

Unsafe

It is not recommended to consume alcohol while taking Saaz Tablet to avoid unpleasant side-effects.

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Pregnancy

Consult your doctor

Saaz Tablet should be recommended in pregnancy only if required. In case, if prescribed to a pregnant woman, it is advised to increase the folate supplementation after consulting your doctor.

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Breast Feeding

Unsafe

Saaz Tablet is excreted in breastmilk and is not recommended especially if the baby is premature or is at the risk of jaundice. It might cause kernicterus (excessive levels of bilirubin in the blood) in the new-born.

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Driving

Safe if prescribed

Saaz Tablet does not affect the ability to drive. However, if you feel drowsy after taking Saaz Tablet , it is advised not to drive.

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Liver

Unsafe

Saaz Tablet is not recommended to use in patients with a history of liver diseases. In other people, rarely, it can cause hepatitis (inflammation of the liver).

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Kidney

Unsafe

Saaz Tablet is not recommended to use in patients with a history of kidney diseases. In other people, rarely it can cause inflammation of the kidneys.

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Children

Consult your doctor

Saaz Tablet should be advised in children only if prescribed by a child specialist.

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Heart

Consult your doctor

Please consult your doctor before using Saaz Tablet if you have pre-existing heart problems. Your doctor will prescribe Saaz Tablet if the benefits outweigh the risks.

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Geriatrics

Caution

Saaz Tablet should be used under caution in geriatric patients as it can lead to serious side effects.

What if I have taken an overdose of Saaz Tablet

Do not take more than the prescribed dose of Saaz Tablet as it may cause an overdose. The symptoms of overdose include stomach pain, seizures (fits), tiredness, nausea and vomiting. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay Well Hydrated: Drink plenty of water throughout the day to help reduce the risk of kidney-related complications.
  • Follow an Appropriate Diet: If you have inflammatory bowel disease, follow your healthcare provider's dietary recommendations, particularly during flare-ups.
  • Protect Your Skin from Sunlight: This medicine may increase sensitivity to sunlight. Use sunscreen and wear protective clothing when spending time outdoors.
  • Stay Physically Active: Gentle exercise such as walking, swimming, or cycling may help maintain joint flexibility and mobility.
  • Be Aware of Colour Changes: The medicine may cause harmless yellow-orange discoloration of urine, sweat, or tears.
     

Health Queries

Is it safe to continue taking my rheumatoid arthritis medications, Saaz (one gram three times a day) and Hcq (200 mg twice a day), during my current eight-week pregnancy, or should I stop them now that my pain and discomfort have improved, especially given my history of three miscarriages?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Both Saaz (sulfasalazine) and HCQ (hydroxychloroquine) are generally safe and crucial for keeping your rheumatoid arthritis stable. Active inflammation from a flare-up can actually pose a higher risk to your pregnancy than these medications. Since you are at eight weeks, it is very important to contact your rheumatologist and obstetrician immediately before making any changes. They will work together to ensure you and your baby stay safe and healthy.

Could taking Tryptomer 25 mg and Saaz 1 gram, combined with eating spinach, cause my tongue to suddenly feel numb, even though I have been on these medicines for a month without any issues?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Since you have tolerated Tryptomer (amitriptyline) and Saaz (sulfasalazine) well for a month, a serious drug interaction is unlikely. Amitriptyline can sometimes cause mild dryness or altered sensations in the mouth. Additionally, spinach contains natural compounds called oxalates, which can leave a temporary rough, tingly, or fuzzy feeling on the tongue, especially if your mouth is dry. This is likely a harmless, temporary reaction. However, please seek immediate medical care if you experience any swelling, difficulty swallowing, or breathing issues. Otherwise, monitor the sensation and mention it to your doctor if it persists.

Could taking SAAZ and folic acid cause side effects like feeling feverish, a headache, body aches, and neck pain?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Yes, sulfasalazine (SAAZ) can sometimes cause side effects like headaches and body aches, particularly when starting the medication. Folic acid is typically very well-tolerated. However, a combination of fever, body aches, and neck pain can also indicate an infection or a hypersensitivity reaction that requires professional evaluation. I highly recommend contacting your prescribing doctor or healthcare provider promptly to discuss these symptoms safely. In the meantime, please rest, stay hydrated, and avoid changing your medication doses without their guidance.

What new treatments or recent research options are available for chronic spinal arthritis (ankylosing spondylitis) to help completely relieve my persistent back pain and stiffness, since my current daily routine of exercises and 2000 mg of Saaz DS is only keeping my symptoms partially controlled and my blood inflammation levels remain slightly elevated?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Since your inflammation levels remain elevated, it may be time to discuss advanced treatment options with your rheumatologist. Beyond sulfasalazine, highly effective therapies called biologics?specifically TNF inhibitors or IL-17 inhibitors?are now widely used to directly target and calm the immune response causing your joint inflammation. These treatments have helped many people find significant, long-term relief. Please consult your specialist to see if transitioning to one of these targeted therapies is the right next step for you.

With my inflammation test numbers (CRP and ESR) at 10 and 8 while taking Saaz and oral steroids for my stiffening spine, am I at risk of becoming permanently disabled, and is there any surgery that can restore flexibility to my back now that six of my backbones have already grown together?

Veda Maddala

Veda Maddala

M Pharmacy

Your inflammation numbers (CRP 10, ESR 8) are actually quite stable, showing that sulfasalazine (Saaz) and your steroids are helping manage the disease. While surgery cannot safely undo fused vertebrae to restore lost flexibility, physical therapy and gentle exercise are highly effective at preserving your remaining movement. Having fused bones does not mean permanent disability is inevitable. By staying active and working closely with your doctor, you can maintain a good quality of life and protect your spine's mobility.
health query

Have a query?

How Soon It Starts Working

The time required for Saaz Tablet to start to work: The time required for Saaz Tablet to show its action is not clinically established. The time for which the effects of Saaz Tablet last: The duration of action for Saaz Tablet is not clinically established.

What if you forget to take Saaz Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store Saaz Tablet at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from moisture and light.

Drug Warnings

  • Attend Regular Blood Tests: Your doctor may monitor your blood counts, liver function, and kidney function during treatment.
  • Monitor for Signs of Infection: Report persistent fever, chills, sore throat, or other symptoms of infection to your healthcare provider.
  • Check for Skin Reactions: Seek medical advice if you develop a rash, blistering, or unusual skin changes.
  • Inform Healthcare Providers: Tell your doctor, dentist, or surgeon that you are taking this medicine before any procedure.
  • Be Aware of Contact Lens Staining: Soft contact lenses may become permanently discoloured due to changes in tear colour.
     

Drug-Drug Interactions

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Drug-Drug Interactions
Inform your doctor if you are taking any of the following medicines, as they may interact with Saaz Tablet :

  • Digoxin: Sulfasalazine may reduce the absorption of digoxin, potentially decreasing its effectiveness.
  • Blood Thinners: Medicines such as warfarin may increase the risk of bleeding when used together.
  • Oral Diabetes Medicines: May increase the risk of low blood sugar in some patients.
  • Methotrexate: Concurrent use may increase the risk of certain side effects and may require closer monitoring.
  • Folic Acid Supplements: Sulfasalazine may reduce folic acid absorption, and supplementation may be recommended.

Drug-Food Interactions

  • Iron Supplements: Iron may reduce the absorption of sulfasalazine. Your doctor may recommend separating the timing of these medicines.
  • Alcohol: Excessive alcohol consumption may increase the risk of liver-related side effects.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Saaz Tablet , as it may worsen your condition or require additional monitoring:

  • Kidney Disease: May increase the risk of kidney-related complications.
  • Liver Disease: May increase the risk of liver toxicity.
  • Asthma: Some people with asthma may be more likely to experience allergic or sensitivity reactions.
  • Blood Disorders: Sulfasalazine may affect blood cell production and require closer monitoring.
     
SulfasalazineCidofovir
Critical
SulfasalazineWarfarin
Severe

Drug-Drug Interactions

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SulfasalazineCidofovir
Critical
How does the drug interact with Saaz Tablet:
Coadministration of Cidofovir with Saaz Tablet can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Saaz Tablet with Cidofovir is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
SulfasalazineWarfarin
Severe
How does the drug interact with Saaz Tablet:
Coadministration of warfarin with Saaz Tablet can increase the risk of unusual bleeding disorder.

How to manage the interaction:
Although taking Saaz Tablet and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache; and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
SulfasalazineDicoumarol
Severe
How does the drug interact with Saaz Tablet:
Using Dicoumarol together with Saaz Tablet may increase the risk or severity of bleeding. The risk increases in patients with a history of liver or kidney disorders.

How to manage the interaction:
There may be a possibility of interaction between Saaz Tablet and Dicoumarol, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness call a doctor. Do not discontinue any medications without consulting a doctor.
SulfasalazineLeflunomide
Severe
How does the drug interact with Saaz Tablet:
Taking Saaz Tablet with leflunomide can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between Saaz Tablet and leflunomide, it can be taken if prescribed by a doctor. Contact a doctor immediately if you develop paleness, fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
SulfasalazinePrilocaine
Severe
How does the drug interact with Saaz Tablet:
Coadministration of Saaz Tablet with Prilocaine can increase the risk of methemoglobinemia, (a rare red blood cell disorder in which oxygen carrying effectively reduces).

How to manage the interaction:
Although taking Prilocaine and Saaz Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineBupivacaine
Severe
How does the drug interact with Saaz Tablet:
Coadministration of bupivacaine and Saaz Tablet may result in methemoglobinemia, an uncommon disorder that lowers the blood's ability to carry oxygen, which can induce oxygen deprivation in tissues and essential organs.

How to manage the interaction:
Although taking bupivacaine and Saaz Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineTenofovir alafenamide
Severe
How does the drug interact with Saaz Tablet:
The combined use of Saaz Tablet and Tenofovir alafenamide can increase the risk or severity of of kidney problems.

How to manage the interaction:
Taking Saaz Tablet and tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineTacrolimus
Severe
How does the drug interact with Saaz Tablet:
Taking tacrolimus with Saaz Tablet will have an additive effect and may increase the risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Saaz Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
SulfasalazineCiclosporin
Severe
How does the drug interact with Saaz Tablet:
Coadministration of Saaz Tablet with ciclosporin may significantly increase the side effects on kidneys.

How to manage the interaction:
Although there is a possible interaction between Saaz Tablet and ciclosporin, they can be taken together if your doctor has prescribed them. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without first talking to a doctor.
SulfasalazineSirolimus
Severe
How does the drug interact with Saaz Tablet:
Coadministration of Sirolimus together with Saaz Tablet may increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Sirolimus with Saaz Tablet together can result in an interaction, but it can be taken if a doctor has advised it. Contact a doctor if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Saaz Tablet is used to treat bowel diseases (ulcerative colitis, Crohn's disease), skin-related problems (psoriasis), and chronic joint diseases (rheumatoid arthritis, ankylosing spondylitis).
Yes, Saaz Tablet is contraindicated in patients with intestinal or urinary obstruction, patients with porphyria (liver disorders), and patients hypersensitive to sulfasalazine, its metabolites, sulfonamides, or salicylates.
In some men, sulfasalazine may temporarily reduce sperm count. This effect is generally reversible after treatment is stopped. Talk to your doctor or pharmacist if you are planning a family.
Yes, Saaz Tablet is safe to use in breastfeeding. However, please inform your doctor if the baby is premature or is at risk of jaundice as this medicine might not be advised in such cases.
Yes, Saaz Tablet can rarely affect blood cells and may cause conditions such as leukopenia (low white blood cell count) or, in rare cases, agranulocytosis. Because of this risk, your doctor may recommend regular monitoring with blood counts and other laboratory tests, including kidney and liver function tests. Monitoring is usually more frequent during the first year of treatment. Contact your doctor if you develop symptoms such as fever, sore throat, rash, or signs of infection.
No, Saaz Tablet is a disease-modifying anti-rheumatic drug’ (DMARD) and not a painkiller. So, if you are taking a painkiller before starting this medicine, you can continue taking it along with Saaz Tablet .
No, Saaz Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side-effects. If you think your symptoms are not improving, please consult your doctor.
Saaz Tablet may cause central nervous system adverse effects such as serious psychiatric problems including mania, depression, and psychosis, and these symptoms have been reported to occur only infrequently.
The side effects of Saaz Tablet include headache, nausea, indigestion and watery diaarhoea. If these side effects persist or worsen, please consult your doctor.
Improvement may take several weeks after starting Saaz Tablet . Some patients notice symptom relief within 4–6 weeks, while the full benefits may take 8–12 weeks or longer, especially in rheumatoid arthritis. Continue taking the medicine as prescribed and do not stop treatment without consulting your doctor.
You are recommended to avoid using azathioprine along with Saaz Tablet as it may decrease blood cell count, which can be a serious side effect. However, please consult your doctor before taking other medicines with Saaz Tablet to avoid drug interactions.
Yes. Saaz Tablet may cause harmless yellow-orange discoloration of urine, sweat, saliva, or tears. Because of this, soft contact lenses may become permanently stained and should be used with caution. However, yellowing of the skin or eyes should be reported to your doctor immediately, as it may indicate a liver problem.
No. The tablets should generally be swallowed whole with water unless your doctor specifically advises otherwise. Crushing or chewing them may affect how the medicine works. Talk to your doctor or pharmacist if you have difficulty swallowing tablets.
Your doctor will determine whether this medicine is appropriate during pregnancy based on your individual circumstances. Folic acid supplementation may be recommended. Talk to your doctor or pharmacist if you are pregnant or planning to become pregnant.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 007073S124Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Sulphaslazine2 - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Sulfasalazine Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Sulfasalazine [EMC Label]. 2010. [Accessed on 23 Jan. 2019]Check here
  5. Sulfasalazine [Patient Information Leaflet]. 2018. [Accessed on 18 Jun. 2019]Check here
  6. Sulfasalazine [Prescribing Information]. 2014. [Accessed on 18 Jun. 2019]Check here
  7. Choi J, Fenando A Sulfasalazine. [Updated 2022 Nov 11]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023Check here

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - SAA0001
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