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  1. Home
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  3. Saface-H 5/12.5Mg Tablet 10'S

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Saface-H 5/12.5Mg Tablet 10'S, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Saface-H 5/12.5Mg Tablet is used to treat high blood pressure. It contains Ramipril and Hydrochlorothiazide, which relax the blood vessels and increase the amount of urine passed out from the kidneys. Sometimes, you may experience side effects such as headaches, tiredness, a slow heart rate, and nausea. Inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Composition :

HYDROCHLOROTHIAZIDE-12.50MG + RAMIPRIL-5MG

Manufacturer/Marketer :

Morepen Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Saface-H 5/12.5Mg Tablet

Saface-H 5/12.5Mg Tablet is used to treat blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Saface-H 5/12.5Mg Tablet contains Ramipril and Hydrochlorothiazide. Ramipril relaxes the blood vessels and improves blood flow. Hydrochlorothiazide works by increasing the amount of urine passed out from the kidneys.

Sometimes, you may experience headaches, tiredness, a slow heart rate, and nausea. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Saface-H 5/12.5Mg Tablet if you are allergic to any of its components. Saface-H 5/12.5Mg Tablet is not recommended in pregnancy and lactation. Keep your doctor informed about your health condition and medications to prevent any interactions.

Uses of Saface-H 5/12.5Mg Tablet

Saface-H 5/12.5Mg Tablet is used in the treatment of Hypertension (high blood pressure). The detailed uses of Saface-H 5/12.5Mg Tablet are as follows:

  • Hypertension (High Blood Pressure): Saface-H 5/12.5Mg Tablet controls blood pressure when single-drug therapy isn’t enough.
  • Prevention of Cardiovascular Events: Saface-H 5/12.5Mg Tablet lowers risk of heart attack, stroke, and heart failure.

Have a query?

Directions for Use

  • Take Saface-H 5/12.5Mg Tablet with or without food as advised by your doctor.
  • It is advised to take Saface-H 5/12.5Mg Tablet once daily in the morning; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Saface-H 5/12.5Mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Saface-H 5/12.5Mg Tablet contains Ramipril and Hydrochlorothiazide, which lower and maintain healthy blood pressure levels.
  • By controlling hypertension, it helps prevent serious cardiovascular events such as heart attack, stroke, and heart failure.
  • Ramipril, an ACE inhibitor, blocks the production of angiotensin II, which relaxes and widens blood vessels to improve blood flow.
  • Hydrochlorothiazide acts as a diuretic, increasing urine output to remove extra salt and water from the body, thereby reducing fluid retention (oedema).
  • By lowering both blood pressure and fluid buildup, Saface-H 5/12.5Mg Tablet helps the heart pump blood more efficiently.
  • It helps relieve swelling associated with heart, liver, kidney, or lung disorders by reducing excess fluid accumulation.
  • The combined action of both ingredients maintains optimal circulation and prevents strain on the heart and arteries.

How Saface-H 5/12.5Mg Tablet Works

Saface-H 5/12.5Mg Tablet contains two medicines: Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretic or water pill). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers high blood pressure by blocking a naturally occurring substance known as angiotensin II (which tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Saface-H 5/12.5Mg Tablet

An overdose of Saface-H 5/12.5Mg Tablet may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Saface-H 5/12.5Mg Tablet if you are allergic to any of its components, or if you have low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (patients with nil urine output), or aortic stenosis (heart valve problem).
  • Inform your doctor if you have had a heart attack, diabetes, kidney disease or liver disease
  • Consult your doctor if you are pregnant, planning to get pregnant or breastfeeding.
  • Do not consume alcohol with Saface-H 5/12.5Mg Tablet as it may increase the risk of low blood pressure.
  • Avoid potassium supplements with Saface-H 5/12.5Mg Tablet as they may lead to high potassium levels in the blood
  • Let your doctor know if you are taking any other medicines, including supplements or herbal products.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
  • Including heart-healthy omega-3 fatty acid acid-containing foods in your daily diet.
  • Use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Alcohol

Caution

Saface-H 5/12.5Mg Tablet may enhance the hypotensive (low blood pressure) effect if alcohol is taken along with it. For better advice, you should consult your doctor about whether you can take Saface-H 5/12.5Mg Tablet with alcohol.

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Pregnancy

Unsafe

The use of Saface-H 5/12.5Mg Tablet or any ACE inhibitors (Ramipril) is usually contraindicated during the second and third trimesters of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Saface-H 5/12.5Mg Tablet .

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Breast Feeding

Caution

Use of Saface-H 5/12.5Mg Tablet is not recommended during the breastfeeding stage.

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Driving

Caution

Drive with caution, Saface-H 5/12.5Mg Tablet may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Rare elevation in the liver enzymes (like bilirubin) has been observed while taking Saface-H 5/12.5Mg Tablet , so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.

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Kidney

Caution

Saface-H 5/12.5Mg Tablet to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. Saface-H 5/12.5Mg Tablet should be given with precaution in hemodialysis conditions.

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Children

Caution

Saface-H 5/12.5Mg Tablet is not recommended for children. The safety and effectiveness of Saface-H 5/12.5Mg Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Saface-H 5/12.5Mg Tablet or not.

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Heart

Saface-H 5/12.5Mg Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Saface-H 5/12.5Mg Tablet should be used under caution in geriatric patients. Please consult your physician.

FAQs

Saface-H 5/12.5Mg Tablet is used to treat hypertension (high blood pressure).

Saface-H 5/12.5Mg Tablet contains Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretic or water pill). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers high blood pressure by blocking a naturally occurring substance known as angiotensin II (which tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes.

Yes, Saface-H 5/12.5Mg Tablet can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking Saface-H 5/12.5Mg Tablet . In case you feel dizzy or lightheaded, it is recommended to rest for some time until you feel better.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

If you forget to take Saface-H 5/12.5Mg Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.

Yes, in some cases, Saface-H 5/12.5Mg Tablet may affect your serum potassium level, so consult your doctor before using potassium supplements or its salt substitutes.

Saface-H 5/12.5Mg Tablet should not be used if you have a history of a serious allergic reaction, including swelling of the face/lips/tongue/throat (angioedema) and an inability to pass urine. Before going outdoor in the sun, try to wear sunscreen (SPF) and avoid sunlamps and tanning booths as prolonged intake of Saface-H 5/12.5Mg Tablet may cause your skin to be sensitive to the sunlight.

Yes, if you have diabetes, Saface-H 5/12.5Mg Tablet may change your blood sugar level, so check your blood sugar regularly as directed. Tell your doctor if you have high blood sugar (hyperglycemia) symptoms like increased thirst/urination or signs of low blood sugar (hypoglycemia) such as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Your doctor might adjust your dose of Saface-H 5/12.5Mg Tablet .

The common side effects of Saface-H 5/12.5Mg Tablet include headaches, tiredness, slow heart rate, and nausea. Most of these side effects gradually resolve over time; however, if they persist, please inform your doctor.

No, you should not stop treatment with Saface-H 5/12.5Mg Tablet even if you feel an improvement in your symptoms because high blood pressure often has no symptoms and can shoot up at any time. Continue taking it for as long as it has been advised by your doctor.

Yes, you can take Saface-H 5/12.5Mg Tablet every day if advised by the doctor. Just make sure to follow your doctor’s instructions regarding how long to use it. Taking it for years on your own without your doctor’s approval could be fatal.

Country of origin

India

Manufacturer/Marketer address

409, Antriksh Bhawan, 22 Kasturba Gandhi Marg, New Delhi - 110 001
Other Info - SAF0322

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 18, 2025 | 7:33 AM IST

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Reference

  1. https://www.healthline.com/health/ramipril-oral-capsule
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019901s060lbl.pdf
  3. https://www.nhs.uk/medicines/ramipril/
  4. https://www.sps.nhs.uk/articles/safety-in-lactation-diuretics/
  5. https://www.drugs.com/tips/hydrochlorothiazide-patient-tips

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