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  3. SAFEGUARD 50MG TABLET

SAFEGUARD 50MG TABLET, Pack of 10 TabletS
SAFEGUARD 50MG TABLET, Pack of 10 TabletS
Not for online sale
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
SAFEGUARD 50MG TABLET is used to reduce pain and swelling associated with conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It contains diclofenac and misoprostol which works by inhibiting the release of chemical messengers that cause pain and protecting the stomach lining from acid. In some cases, this medicine may cause side effects such as diarrhoea, stomach/abdominal pain, nausea, heartburn, drowsiness, and dizziness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

DICLOFENAC-50MG + MISOPROSTOL-200MCG

Manufacturer/Marketer :

Pulse Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About SAFEGUARD 50MG TABLET

SAFEGUARD 50MG TABLET belongs to a class of non-steroidal anti-inflammatory drugs used to reduce pain and swelling in the joints associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (pain and stiffness in the backbone). Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time. The arthritis symptoms include joint pain, stiffness, redness, tenderness, swelling in and around joints, and reduced movement of joints.

SAFEGUARD 50MG TABLET is a combination drug containing diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Take SAFEGUARD 50MG TABLET as prescribed by your doctor. Depending on your medical conditions, you are advised to take SAFEGUARD 50MG TABLET for as long as your doctor has prescribed it for you. You may experience diarrhoea, stomach/abdominal pain, nausea, heartburn, drowsiness, and dizziness. Most of the side effects of SAFEGUARD 50MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before using the SAFEGUARD 50MG TABLET, tell your doctor if you have had a heart attack or stroke, stomach or bowel disorder, liver disease, porphyria ( inherited blood disorder), asthma, high blood pressure, diabetes, and stomach or intestinal bleeding. Do not take SAFEGUARD 50MG TABLET if you are a pregnant or breastfeeding woman. Consumption of alcohol should be avoided during the treatment with SAFEGUARD 50MG TABLET as it may lead to an increased risk of liver damage. SAFEGUARD 50MG TABLET is not recommended for use in children. Limit alcoholic beverages while on this medication.

Uses of SAFEGUARD 50MG TABLET

Treatment of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

SAFEGUARD 50MG TABLET is used to treat aches and pains and musculoskeletal and joint pain problems due to arthritis. SAFEGUARD 50MG TABLET contains diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

How SAFEGUARD 50MG TABLET Works

SAFEGUARD 50MG TABLET is a combination drug containing diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of SAFEGUARD 50MG TABLET

Take SAFEGUARD 50MG TABLET only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include stomach pain, nausea, vomiting, diarrhoea, confusion, drowsiness, low muscle tone, uncontrollable shaking of a part of the body, seizures, shortness of breath, fever, and fast, pounding, or slow heartbeat. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Consumption of alcohol should be avoided during the treatment with SAFEGUARD 50MG TABLET. Patients with stomach ulcers, gastric bleeding, heart failure, and high blood pressure should not take SAFEGUARD 50MG TABLET. If pregnant or breastfeeding, do not take SAFEGUARD 50MG TABLET without talking with the doctor. SAFEGUARD 50MG TABLET is not recommended for children below 18 years old. Seek medical help immediately if you have signs of a heart attack or stroke. Stop using SAFEGUARD 50MG TABLET and call your doctor immediately if you notice heart problems, kidney problems, liver problems, or stomach bleeding signs.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
MisoprostolDinoprostone
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Safeguard 50mg Tablet:
Co-administration of Safeguard 50mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Safeguard 50mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
MisoprostolDinoprostone
Severe
How does the drug interact with Safeguard 50mg Tablet:
Combined use of Safeguard 50mg Tablet and Dinoprostone can affect the metabolism of Safeguard 50mg Tablet.

How to manage the interaction:
Taking Safeguard 50mg Tablet and Dinoprostone together can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MisoprostolOxytocin
Severe
How does the drug interact with Safeguard 50mg Tablet:
Coadministration of Safeguard 50mg Tablet and Oxytocin can enhance the action of oxytocin. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Safeguard 50mg Tablet and Oxytocin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden or severe stomach pain, unexplained vaginal bleeding, Fast heart rate or low blood pressure in the pregnant person, diarrhea, or dehydration, consult to a doctor. Do not discontinue any medications without consulting a doctor.
DiclofenacCidofovir
Severe
How does the drug interact with Safeguard 50mg Tablet:
Coadministration of Safeguard 50mg Tablet with cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Safeguard 50mg Tablet and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Safeguard 50mg Tablet:
Co-administration of Safeguard 50mg Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Safeguard 50mg Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacFurosemide
Severe
How does the drug interact with Safeguard 50mg Tablet:
Concomitant administration of Safeguard 50mg Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Safeguard 50mg Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
DiclofenacTenofovir disoproxil
Severe
How does the drug interact with Safeguard 50mg Tablet:
Co-administration of Safeguard 50mg Tablet with tenofovir disoproxil may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Safeguard 50mg Tablet and Tenofovir disoproxil but they can be taken together if your doctor has prescribed them. However consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacHuman immunoglobulin
Severe
How does the drug interact with Safeguard 50mg Tablet:
Taking Safeguard 50mg Tablet with human immunoglobulin may increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Safeguard 50mg Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
DiclofenacNaproxen
Severe
How does the drug interact with Safeguard 50mg Tablet:
Coadministration of Safeguard 50mg Tablet and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Safeguard 50mg Tablet and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacTenofovir alafenamide
Severe
How does the drug interact with Safeguard 50mg Tablet:
Co-administration of Safeguard 50mg Tablet and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Safeguard 50mg Tablet and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS

SAFEGUARD 50MG TABLET Substitute

Substitutes safety advice

  • SAFEGUARD TABLET

    by Others

    ₹10.44per tablet

Product Substitutes

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Alcohol

Unsafe

Do not consume alcohol along with SAFEGUARD 50MG TABLET as it can cause unpleasant side-effects like gastric bleeding.

bannner image

Pregnancy

Unsafe

Please consult your doctor if you are pregnant; your doctor will prescribe SAFEGUARD 50MG TABLET only if the benefits outweigh the risks. Taking SAFEGUARD 50MG TABLET in the last 20 weeks of pregnancy may cause serious kidney or heart problems in the unborn baby.

bannner image

Breast Feeding

Caution

While SAFEGUARD 50MG TABLET may pass in the lactating mother's breast milk, So, do it is advisable to take it only if prescribed by your doctor.

bannner image

Driving

Caution

SAFEGUARD 50MG TABLET may cause dizziness and drowsiness. So, if you observe such symptoms, do not drive.

bannner image

Liver

Caution

Limited information was available for the use of SAFEGUARD 50MG TABLET in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using SAFEGUARD 50MG TABLET in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Limited information was available for the use of SAFEGUARD 50MG TABLET in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using SAFEGUARD 50MG TABLET in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

SAFEGUARD 50MG TABLET not recommended for children under 18 years of age.

Have a query?

FAQs

SAFEGUARD 50MG TABLET is used to reduce pain and swelling associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

SAFEGUARD 50MG TABLET contains diclofenac and misoprostol. Diclofenac works by blocking the action of cyclo-oxygenase (COX) enzyme in the body involved in the production of certain chemical substances such as prostaglandins that cause pain and swelling. Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. Thereby, SAFEGUARD 50MG TABLET helps in relieving pain and swelling associated with different types of arthritis.

No, SAFEGUARD 50MG TABLET is not a narcotic pain killer. It belongs to the non-steroidal anti-inflammatory drugs (NSAIDs) group of medications.

Yes, SAFEGUARD 50MG TABLET can cause dizziness in some patients. They may experience symptoms such as the feeling of fainting, weakness, or lightheadedness.

SAFEGUARD 50MG TABLET may increase the risk of heart problems such as heart attack, especially when used in high doses or for a prolonged duration, and in patients who are smokers, have high blood pressure, diabetes, or high cholesterol. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking SAFEGUARD 50MG TABLET. However, it is recommended to take SAFEGUARD 50MG TABLET in the dose and for the duration as prescribed by your doctor.

SAFEGUARD 50MG TABLET is not recommended for asthma patients as it may worsen the condition. Therefore, please inform your doctor if you have asthma or a history of asthma due to the use of aspirin or any other non-steroidal drugs.

No, SAFEGUARD 50MG TABLET does not cure arthritis. SAFEGUARD 50MG TABLET is only used to relieve symptoms of arthritis such as joint pain, swelling, and stiffness.

SAFEGUARD 50MG TABLET is used to treat pain associated with arthritis. If you have a toothache, it is recommended that you consult your doctor before using SAFEGUARD 50MG TABLET.

SAFEGUARD 50MG TABLET may cause gastrointestinal problems. Therefore, do not take SAFEGUARD 50MG TABLET if you have acid reflux or abdominal pain without consulting the doctor.

It's generally not recommended to take SAFEGUARD 50MG TABLET with blood pressure medication without consulting your doctor as it may increase blood pressure and reduce the effectiveness of blood pressure medications.

The common side effects of SAFEGUARD 50MG TABLET include diarrhoea, stomach or abdominal pain, nausea, heartburn, drowsiness, and dizziness. Most of the side effects of SAFEGUARD 50MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

4F10, Ballad Estates, Tarnaka, Hyderabad - 500017, TS, India.
Other Info - SAF0213

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:47 PM IST

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Reference

  1. https://www.drugs.com/diclofenac.html
  2. https://www.medicines.org.uk/emc/files/pil.2660.pdf
  3. https://www.medicines.org.uk/emc/files/pil.1642.pdf
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