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  3. SAFEX 500MG CAPSULE

SAFEX 500MG CAPSULE, Pack of 10 TABLETS
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Composition :

CEFUROXIME-500MG

Manufacturer/Marketer :

Vintage Labs

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About SAFEX 500MG CAPSULE

SAFEX 500MG CAPSULE belongs to the class of antibiotics known as cephalosporin, indicated for treating a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), Mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect) in adults and children above 12 years of age.

SAFEX 500MG CAPSULE is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

You should take SAFEX 500MG CAPSULE only if your doctor has prescribed you. SAFEX 500MG CAPSULE is available in various forms, such as oral tablets, dispersible tablets, and oral suspension. Most bacterial infections get treated within one week, while some conditions might take longer. So, it would be best if you tried to complete the dose your doctor prescribed for the specific bacterial infection. During the treatment with SAFEX 500MG CAPSULE, you may observe some mild and transient nature of common side effects like headache, dizziness,  stomach upset, overgrowth of candida (fungal skin infection), unpleasant taste in the mouth, diaper rashes, and eosinophilia (increased disease-fighting cells WBCs). These side effects are usually in the initial phase and then resolved after some time. However, if these side effects persist, let your doctor know about them.

Overdosage of SAFEX 500MG CAPSULE can cause brain problems (cerebral irritation with fits or convulsions attack). There is no clinical evidence of a SAFEX 500MG CAPSULE effect on the mother or baby during pregnancy. However, one should take the SAFEX 500MG CAPSULE with caution. SAFEX 500MG CAPSULE is excreted in the breastmilk, so the nursing mother should cautiously take SAFEX 500MG CAPSULE. This antibiotic may cause dizziness, so patients should be cautious while driving a motor vehicle or operating machinery. SAFEX 500MG CAPSULE is not recommended for people allergic or hypersensitive to SAFEX 500MG CAPSULE, penicillin, or other beta-lactam antibiotics. In the initial stage of the treatment, you might have diarrhoea and abdominal cramps due to loss of gut flora (good intestinal/gut bacteria that aids digestion). So, the doctor may prescribe you prebiotics or probiotics to increase the number of gut flora. You can drink alcoholic beverages while taking amoxicillin, as it does not interact with SAFEX 500MG CAPSULE. Liver and kidney-affected people should take this medication with caution.

Directions for Use

• SAFEX 500MG CAPSULE can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow SAFEX 500MG CAPSULE as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

SAFEX 500MG CAPSULE treats a wide range of bacterial infections caused due to gram-positive and gram-negative bacteria. It helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, SAFEX 500MG CAPSULE also prevents in spreading of the infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. The usual course of SAFEX 500MG CAPSULE is seven days (5-10 days). But, your doctor might prescribe you SAFEX 500MG CAPSULE for a longer duration depending on the condition of infection. SAFEX 500MG CAPSULE has excellent antibacterial activity against gram-positive and gram-negative bacteria, including Staphylococcus aureus, Haemophilus para influenza, Streptococcus pneumonia, S. pyrogens, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, and Neisseria gonorrhoeae.

How SAFEX 500MG CAPSULE Works

SAFEX 500MG CAPSULE is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

Storage

Store in a cool and dry place away from sunlight
Side effects of Safex 500mg Capsule
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.

What if I have taken an overdose of SAFEX 500MG CAPSULE

Do not take more than the prescribed dose of SAFEX 500MG CAPSULE as it may cause overdose. The symptoms of overdose include seizures (fits). If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Special care should be taken by the people taking SAFEX 500MG CAPSULE who have allergic reactions to penicillin or other beta-lactam antibiotics. Use with other antibiotics may lead to a fungal skin infection known as Candida. Prolonged use of SAFEX 500MG CAPSULE may also cause an overgrowth of other pathogens (like enterococci and Clostridium difficile), which can be prevented by stopping SAFEX 500MG CAPSULE. The case of colitis (inflammatory bowel disease) has been reported using SAFEX 500MG CAPSULE. Hence, it is important to consider the proper diagnosis of the patients who developed diarrhoea after taking SAFEX 500MG CAPSULE. If the symptom of diarrhoea persists for a longer duration, the patient may experience abdominal cramps. In this situation, you should discontinue the intake of SAFEX 500MG CAPSULE immediately. The Jarisch-Herxheimer reaction (caused due to toxins released by the death of bacteria within the body during antibiotic treatment) has been seen in the patients taking SAFEX 500MG CAPSULE for the treatment of Lyme disease. Your ability to perform tasks that require judgment, cognitive, or body movement may be affected, and you may have dizziness. So patients taking SAFEX 500MG CAPSULE should be warned to be cautious when driving or operating machinery.

Drug-Drug Interactions

verifiedApollotooltip
CefuroximeBCG vaccine
Severe
CefuroximeLepirudin
Severe

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
How does the drug interact with Safex 500mg Capsule:
Co-administration of Safex 500mg Capsule may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Safex 500mg Capsule. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Safex 500mg Capsule:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Safex 500mg Capsule.

How to manage the interaction:
Although taking Safex 500mg Capsule and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
CefuroximeDalteparin
Severe
How does the drug interact with Safex 500mg Capsule:
Co-administration of Dalteparin and Safex 500mg Capsule can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Safex 500mg Capsule with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
CefuroximeRanitidine
Moderate
How does the drug interact with Safex 500mg Capsule:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
vv

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of SAFEX 500MG CAPSULE to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.

  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of SAFEX 500MG CAPSULE.

  • Avoid intake of alcoholic beverages with SAFEX 500MG CAPSULE as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the SAFEX 500MG CAPSULE in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

SAFEX 500MG CAPSULE Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with SAFEX 500MG CAPSULE.

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Pregnancy

Safe if prescribed

SAFEX 500MG CAPSULE is a pregnancy category B drug. So, SAFEX 500MG CAPSULE can be safely taken by pregnant women if prescribed by the doctor.

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Breast Feeding

Safe if prescribed

SAFEX 500MG CAPSULE is excreted in human milk, caution should be exercised. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

No studies on the effects on the ability to drive and use machines have been performed. However, as this medicine may cause dizziness, patients should be warned to be cautious when driving or operating machinery.

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Liver

Caution

Consult your doctor, there is no substantial research yet on the use of SAFEX 500MG CAPSULE

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Kidney

Caution

Consult your doctor, there is no substantial research yet on the use of SAFEX 500MG CAPSULE

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Children

Safe if prescribed

SAFEX 500MG CAPSULE can be given safely to children provided dose has been prescribed by a child specialist. However, There is no clinical evidences of using SAFEX 500MG CAPSULE in children under the age of 3 months.

Have a query?

FAQs

SAFEX 500MG CAPSULE is used to treat a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect).

SAFEX 500MG CAPSULE is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.

You should avoid taking SAFEX 500MG CAPSULE with oral birth control pills, medicines that reduces gastric acidity (like antacids, omeprazole), immuno suppressing drugs (mycophenolate or mycophenolic), medicines used for reducing uric acid (probenecid), and some urinary glucose tests. Besides this, it also interacts with thyphoid and BCG vaccines.

Depending upon the severity of your medical condition your doctor may prescribe it to you daily for a specific duration. The usual dose ofSAFEX 500MG CAPSULE is 7 days (5-10 days), but depending on your current infection state your doctor may extend your dose intake for more days.

Try to stay well hydrated by drinking at least 6 glass of water or other fluid per day. Keep your underwear clean and try to use underwear made of cotton to avoid the spread of infection. Always keep your bladder empty as much possible by peeing regularly. Your doctor may prescribe cranberry juice with antibiotics to treat urinary tract infection.

After taking an antibiotic you may need to wait for up to three hours for eating or drinking any dairy products include milk as well as butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also work dampen the effect of antibiotics.

If you have taken accidently over dosage of SAFEX 500MG CAPSULE, you may have diarrhoea, nausea or vomiting. In rare cases it can also cause convulsion or seizures (fits). Try to reach out to doctor in this case.

No. SAFEX 500MG CAPSULE treats only bacterial infection. Cough, flu or cold are usually caused due to the viruses. So, you should consult doctor for these conditions.

Yes. SAFEX 500MG CAPSULE may interact with birth control pills and lowers its efficiency. So, you should tell your doctor if your are using any birth control pills.

No. You should complete the full course of SAFEX 500MG CAPSULE as your doctor prescribes. After completing the full course, the SAFEX 500MG CAPSULE will work. You must take SAFEX 500MG CAPSULE at the right dose, times, and for the right number of days.

SAFEX 500MG CAPSULE might be a safer alternative if you are allergic to amoxicillin. However, please consult the doctor before starting SAFEX 500MG CAPSULE.

SAFEX 500MG CAPSULE helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections.

SAFEX 500MG CAPSULE may cause dizziness in some cases. Therefore, drive or operate machinery only if you are alert.

Do not discontinue SAFEX 500MG CAPSULE without consulting the doctor. To treat your infection effectively, continue taking SAFEX 500MG CAPSULE for the prescribed duration even though you feel better.

If you miss a dose of SAFEX 500MG CAPSULE take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

SAFEX 500MG CAPSULE may interact with other medications. Consult the doctor if you are taking oral birth control pills, antacids, immuno-suppressing drugs, or medicines used for reducing uric acid.

Avoid alcohol consumption as it might lower the effectiveness of SAFEX 500MG CAPSULE.

SAFEX 500MG CAPSULE can be taken by pregnant or breastfeeding women if prescribed by the doctor. Please consult the doctor if you are pregnant, think you are pregnant, planning for pregnancy or breastfeeding.

Side effects of SAFEX 500MG CAPSULE include headache, dizziness, stomach upset, overgrowth of candida (fungal skin infection), and an unpleasant taste in the mouth. Consult the doctor if the side effects persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

5, Utsav Row House, Opp. SAL Hospital, Thaltej, Ahmedabad – 380 054, Gujarat, India
Other Info - SAF0077

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

May 20, 2025 | 6:21 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050605s048,050672s034lbl.pdf
  2. https://www.medicines.org.uk/emc/product/426
  3. https://www.medicines.org.uk/emc/files/pil.3810.pdf
  4. https://www.drugs.com/tips/cefuroxime-patient-tips

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