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compositionComposition:SULFASALAZINE-1000MG
prescription
Prescription Medicine
info
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Salamax Tablet DR is used to treat bowel diseases (ulcerative colitis, Crohn's disease), skin-related problems (psoriasis), and chronic joint diseases (rheumatoid arthritis, ankylosing spondylitis) in children and adults. It contains Sulfasalazine, which works as an inflammation reducer by acting locally, inhibiting the formation of a chemical known as prostaglandins, that control pain and inflammation. Thus, it helps reduce the inflammation of the intestine, skin, and joints. In some cases, you may experience a sore throat, a fever, unexplained bruising, or ringing in your ears (tinnitus). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SULFASALAZINE-1000MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Salamax Tablet DR

Salamax Tablet DR is a prescription medicine used to reduce inflammation and help manage certain chronic inflammatory conditions. It is commonly prescribed for inflammatory bowel diseases such as ulcerative colitis and for inflammatory joint conditions such as rheumatoid arthritis. By helping control inflammation, this medicine can reduce symptoms and support long-term disease management.

Take Salamax Tablet DR exactly as prescribed by your doctor. It is usually taken with food and a full glass of water to help reduce stomach discomfort. Taking the medicine regularly, even when you feel well, helps maintain symptom control and reduce the risk of disease flare-ups.

Some people may experience mild side effects such as nausea, headache, loss of appetite, or stomach discomfort when starting treatment. These effects are often temporary and may improve as your body adjusts to the medicine. However, contact your doctor promptly if you develop severe skin reactions, unusual bruising or bleeding, yellowing of the skin or eyes, persistent fever, or signs of an allergic reaction.

Before taking Salamax Tablet DR, inform your doctor if you have kidney disease, liver disease, asthma, blood disorders, or a history of allergies to sulfonamides or aspirin-containing medicines. This medicine may not be suitable for people with certain intestinal or urinary tract blockages.

Limit alcohol consumption while taking this medicine, as excessive alcohol use may increase the risk of liver-related side effects. Tell your doctor if you are pregnant, planning to become pregnant, breastfeeding, or trying to conceive so they can determine whether this medicine is appropriate for you. 

Uses of Salamax Tablet DR

Salamax Tablet DR is used to treat inflammatory bowel diseases and inflammatory joint conditions. The detailed uses of Salamax Tablet DR are as follows:

  • Ulcerative Colitis: Helps reduce inflammation in the lining of the large intestine and supports both symptom control and maintenance of remission.
  • Rheumatoid Arthritis: Helps reduce joint pain, swelling, stiffness, and inflammation in people with rheumatoid arthritis.
  • Crohn's Disease: May be used in selected patients with mild-to-moderate inflammatory bowel disease, particularly when inflammation affects the colon.
  • Other Inflammatory Conditions: In certain situations, doctors may prescribe this medicine for other inflammatory disorders based on individual patient needs.

Key Benefits

Salamax Tablet DR helps control chronic inflammation and supports long-term management of inflammatory conditions. Regular treatment may improve comfort, mobility, and overall quality of life.

  • Improved Joint Comfort: Helps reduce pain, stiffness, and swelling associated with inflammatory arthritis.
  • Better Physical Function: Supports improved movement and daily activities by helping control inflammation.
  • Supports Digestive Health: Helps reduce symptoms such as abdominal discomfort, diarrhoea, and rectal bleeding associated with ulcerative colitis.
  • Helps Prevent Disease Flare-Ups: Consistent use may reduce the frequency and severity of symptom recurrence in chronic inflammatory conditions.

Directions for Use

To get the full benefit of Salamax Tablet DR and minimise side effects, follow these simple guidelines:

  • Take the tablet orally with food and a full glass of water.
  • Swallow the tablet whole. Do not crush, chew, or break it unless specifically instructed by your doctor.
  • Drink plenty of fluids throughout the day to help support healthy kidney function.
  • Take the medicine at the same time each day to maintain consistent levels in your body.
  • Continue taking the medicine regularly unless your doctor advises otherwise.
  • Always follow your doctor's exact instructions regarding dosage and duration of treatment.
     

How Salamax Tablet DR Works

Salamax Tablet DR contains sulfasalazine. After it reaches the intestine, natural bacteria break the medicine into active components that help reduce inflammation. Reduces Inflammation in the Bowel: One component acts directly within the intestine to help decrease inflammation and tissue irritation. Modulates Immune Activity: The medicine helps regulate inflammatory processes that contribute to joint swelling and stiffness in rheumatoid arthritis. Supports Long-Term Disease Control: By reducing inflammation in affected tissues, the medicine helps improve symptoms and may slow disease progression in certain conditions. Through these actions, Salamax Tablet DR helps manage symptoms and support long-term control of inflammatory diseases.
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Alcohol

Unsafe

It is not recommended to consume alcohol while taking Salamax Tablet DR to avoid unpleasant side-effects.

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Pregnancy

Consult your doctor

Salamax Tablet DR should be recommended in pregnancy only if required. In case, if prescribed to a pregnant woman, it is advised to increase the folate supplementation after consulting your doctor.

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Breast Feeding

Unsafe

Salamax Tablet DR is excreted in breastmilk and is not recommended especially if the baby is premature or is at the risk of jaundice. It might cause kernicterus (excessive levels of bilirubin in the blood) in the new-born.

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Driving

Safe if prescribed

Salamax Tablet DR does not affect the ability to drive. However, if you feel drowsy after taking Salamax Tablet DR, it is advised not to drive.

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Liver

Unsafe

Salamax Tablet DR is not recommended to use in patients with a history of liver diseases. In other people, rarely, it can cause hepatitis (inflammation of the liver).

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Kidney

Unsafe

Salamax Tablet DR is not recommended to use in patients with a history of kidney diseases. In other people, rarely it can cause inflammation of the kidneys.

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Children

Consult your doctor

Salamax Tablet DR should be advised in children only if prescribed by a child specialist.

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Heart

Consult your doctor

Please consult your doctor before using Salamax Tablet DR if you have pre-existing heart problems. Your doctor will prescribe Salamax Tablet DR if the benefits outweigh the risks.

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Geriatrics

Caution

Salamax Tablet DR should be used under caution in geriatric patients as it can lead to serious side effects.

What if I have taken an overdose of Salamax Tablet DR

Do not take more than the prescribed dose of Salamax Tablet DR as it may cause an overdose. The symptoms of overdose include stomach pain, seizures (fits), tiredness, nausea and vomiting. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay Well Hydrated: Drink plenty of water throughout the day to help reduce the risk of kidney-related complications.
  • Follow an Appropriate Diet: If you have inflammatory bowel disease, follow your healthcare provider's dietary recommendations, particularly during flare-ups.
  • Protect Your Skin from Sunlight: This medicine may increase sensitivity to sunlight. Use sunscreen and wear protective clothing when spending time outdoors.
  • Stay Physically Active: Gentle exercise such as walking, swimming, or cycling may help maintain joint flexibility and mobility.
  • Be Aware of Colour Changes: The medicine may cause harmless yellow-orange discoloration of urine, sweat, or tears.
     
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Have a query?

How Soon It Starts Working

The time required for Salamax Tablet DR to start to work: The time required for Salamax Tablet DR to show its action is not clinically established. The time for which the effects of Salamax Tablet DR last: The duration of action for Salamax Tablet DR is not clinically established.

What if you forget to take Salamax Tablet DR

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store Salamax Tablet DR at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from moisture and light.

Drug Warnings

  • Attend Regular Blood Tests: Your doctor may monitor your blood counts, liver function, and kidney function during treatment.
  • Monitor for Signs of Infection: Report persistent fever, chills, sore throat, or other symptoms of infection to your healthcare provider.
  • Check for Skin Reactions: Seek medical advice if you develop a rash, blistering, or unusual skin changes.
  • Inform Healthcare Providers: Tell your doctor, dentist, or surgeon that you are taking this medicine before any procedure.
  • Be Aware of Contact Lens Staining: Soft contact lenses may become permanently discoloured due to changes in tear colour.
     

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Drug-Drug Interactions
Inform your doctor if you are taking any of the following medicines, as they may interact with Salamax Tablet DR:

  • Digoxin: Sulfasalazine may reduce the absorption of digoxin, potentially decreasing its effectiveness.
  • Blood Thinners: Medicines such as warfarin may increase the risk of bleeding when used together.
  • Oral Diabetes Medicines: May increase the risk of low blood sugar in some patients.
  • Methotrexate: Concurrent use may increase the risk of certain side effects and may require closer monitoring.
  • Folic Acid Supplements: Sulfasalazine may reduce folic acid absorption, and supplementation may be recommended.

Drug-Food Interactions

  • Iron Supplements: Iron may reduce the absorption of sulfasalazine. Your doctor may recommend separating the timing of these medicines.
  • Alcohol: Excessive alcohol consumption may increase the risk of liver-related side effects.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Salamax Tablet DR, as it may worsen your condition or require additional monitoring:

  • Kidney Disease: May increase the risk of kidney-related complications.
  • Liver Disease: May increase the risk of liver toxicity.
  • Asthma: Some people with asthma may be more likely to experience allergic or sensitivity reactions.
  • Blood Disorders: Sulfasalazine may affect blood cell production and require closer monitoring.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[GASTROINTESTINAL AGENTS]

FAQs

Salamax Tablet DR is used to treat bowel diseases (ulcerative colitis, Crohn's disease), skin-related problems (psoriasis), and chronic joint diseases (rheumatoid arthritis, ankylosing spondylitis).
Yes, Salamax Tablet DR is contraindicated in patients with intestinal or urinary obstruction, patients with porphyria (liver disorders), and patients hypersensitive to sulfasalazine, its metabolites, sulfonamides, or salicylates.
In some men, sulfasalazine may temporarily reduce sperm count. This effect is generally reversible after treatment is stopped. Talk to your doctor or pharmacist if you are planning a family.
Yes, Salamax Tablet DR is safe to use in breastfeeding. However, please inform your doctor if the baby is premature or is at risk of jaundice as this medicine might not be advised in such cases.
Yes, Salamax Tablet DR can rarely affect blood cells and may cause conditions such as leukopenia (low white blood cell count) or, in rare cases, agranulocytosis. Because of this risk, your doctor may recommend regular monitoring with blood counts and other laboratory tests, including kidney and liver function tests. Monitoring is usually more frequent during the first year of treatment. Contact your doctor if you develop symptoms such as fever, sore throat, rash, or signs of infection.
No, Salamax Tablet DR is a disease-modifying anti-rheumatic drug’ (DMARD) and not a painkiller. So, if you are taking a painkiller before starting this medicine, you can continue taking it along with Salamax Tablet DR.
No, Salamax Tablet DR should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side-effects. If you think your symptoms are not improving, please consult your doctor.
Salamax Tablet DR may cause central nervous system adverse effects such as serious psychiatric problems including mania, depression, and psychosis, and these symptoms have been reported to occur only infrequently.
The side effects of Salamax Tablet DR include headache, nausea, indigestion and watery diaarhoea. If these side effects persist or worsen, please consult your doctor.
Improvement may take several weeks after starting Salamax Tablet DR. Some patients notice symptom relief within 4–6 weeks, while the full benefits may take 8–12 weeks or longer, especially in rheumatoid arthritis. Continue taking the medicine as prescribed and do not stop treatment without consulting your doctor.
You are recommended to avoid using azathioprine along with Salamax Tablet DR as it may decrease blood cell count, which can be a serious side effect. However, please consult your doctor before taking other medicines with Salamax Tablet DR to avoid drug interactions.
Yes. Salamax Tablet DR may cause harmless yellow-orange discoloration of urine, sweat, saliva, or tears. Because of this, soft contact lenses may become permanently stained and should be used with caution. However, yellowing of the skin or eyes should be reported to your doctor immediately, as it may indicate a liver problem.
No. The tablets should generally be swallowed whole with water unless your doctor specifically advises otherwise. Crushing or chewing them may affect how the medicine works. Talk to your doctor or pharmacist if you have difficulty swallowing tablets.
Your doctor will determine whether this medicine is appropriate during pregnancy based on your individual circumstances. Folic acid supplementation may be recommended. Talk to your doctor or pharmacist if you are pregnant or planning to become pregnant.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 007073S124Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Sulphaslazine2 - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Sulfasalazine Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Sulfasalazine [EMC Label]. 2010. [Accessed on 23 Jan. 2019]Check here
  5. Sulfasalazine [Patient Information Leaflet]. 2018. [Accessed on 18 Jun. 2019]Check here
  6. Sulfasalazine [Prescribing Information]. 2014. [Accessed on 18 Jun. 2019]Check here
  7. Choi J, Fenando A Sulfasalazine. [Updated 2022 Nov 11]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023Check here

Country of origin

India
Other Info - SA72393
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