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  3. Samford-400 Tablet 10's

Samford-400 Tablet 10's, Pack of 10 TABLETS
Samford-400 Tablet 10's, Pack of 10 TABLETS
Samford-400 Tablet 10's, Pack of 10 TABLETS
Samford-400 Tablet 10's, Pack of 10 TABLETS
Samford-400 Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Samford-400 Tablet is an amino acid used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. This medicine helps in optimal cellular functioning, monitors and regulates important physiological functions, increases glutathione concentration and metabolism of the liver. Common side effects include nausea, diarrhoea, stomach pain, and flatulence.
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Composition :

S ADENOSYL L METHIONINE DISULFATE TOSYLATE-400MG

Manufacturer/Marketer :

Medford Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Samford-400 Tablet

Samford-400 Tablet is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. Alcoholic liver disease occurs due to liver damage because of excessive alcohol consumption. Osteoarthritis is a condition in which the joints are affected. Depression is a mood disorder and a psychological, physiological and emotional experience that affects the way we think, the things we do and the way we act. 

Samford-400 Tablet contains S-Adenosyl-L-Methionine disulfate tosylate. It is an essential amino acid required for optimal cellular functioning. Samford-400 Tablet is believed to monitor and regulate important physiological functions in living cells. It increases glutathione concentration and metabolism of the liver. Samford-400 Tablet increases chondrocyte proteoglycan synthesis, thereby helping treat osteoarthritis.

Samford-400 Tablet may be taken with or without food, but it is better to take it at a designated time. In some cases, Samford-400 Tablet may cause certain common side effects such as nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking Samford-400 Tablet with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take alcohol with Samford-400 Tablet as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Uses of Samford-400 Tablet

Treatment of Liver disease, osteoarthritis and depression

Have a query?

Directions for Use

• Samford-400 Tablet can be taken with or without food as advised by the doctor.• Strictly follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.• Swallow Samford-400 Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Samford-400 Tablet contains S-Adenosyl-L-Methionine disulfate tosylate. Samford-400 Tablet helps in the synthesis of essential amino acid methionine, which is required for major body functions. It helps provide cellular energy and charge the living cells of various organs like the brain, bones and liver with stamina and fuel, thereby finding application in the treatment of depression, arthritis and liver disease. It helps in major detoxification of the liver in case of diseases caused by a retarded flow of bile such as intrahepatic cholestasis. Samford-400 Tablet also finds use in the treatment of fibromyalgia, attention deficit hyperkinetic disorder and Alzheimer’s disease. However, studies to understand the mechanism behind the same have been inconclusive.

How Samford-400 Tablet Works

Samford-400 Tablet contains S-Adenosyl-L-Methionine disulfate tosylate. It is an essential amino acid required for optimal cellular functioning. Samford-400 Tablet is believed to monitor and regulate important physiological functions in living cells. It increases glutathione concentration and metabolism of the liver. Samford-400 Tablet increases chondrocyte proteoglycan synthesis, thereby helping treat osteoarthritis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Samford-400 Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Samford-400 Tablet

Do not take more than the suggested dose of Samford-400 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of Samford-400 Tablet . Keep your doctor informed of your entire medical history before using Samford-400 Tablet . Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking Samford-400 Tablet with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take Samford-400 Tablet with alcohol as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Load up on lean meats, fatty fish, green leafy vegetables, fruits and nuts to enhance anti-oxidation and optimal functioning of the body.
  • Drink a lot of water and keep yourself hydrated.
  • Maintain a healthy weight by exercising for at least 30 minutes daily. 
  • Stop smoking as this can have a negative effect on the absorption of Samford-400 Tablet and worsen the disease condition.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Samford-400 Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

It is not known whether it is safe to consume alcohol with Samford-400 Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Please consult your doctor before taking Samford-400 Tablet if you are pregnant.

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Breast Feeding

Caution

Please consult your doctor before taking Samford-400 Tablet if you are breastfeeding.

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Driving

Caution

Samford-400 Tablet may rarely cause drowsiness and dizziness. Exercise caution while driving in case of these side effects.

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Liver

Consult your doctor

Samford-400 Tablet is possibly safe on the liver. Please consult your doctor in case of any concerns.

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Kidney

Consult your doctor

Samford-400 Tablet is possibly safe on the kidney. Please consult your doctor in case of any concerns.

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Children

Caution

It is not established if Samford-400 Tablet is safe to use in children. Please consult the treating doctor in case of any concerns.

FAQs

Samford-400 Tablet is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression.

Samford-400 Tablet works by synthesis of methionine, which is an essential amino acid required for cellular energy.

Please see an orthopaedic doctor if you have had a fracture. Samford-400 Tablet is used in the case of arthritis and has limited use in the treatment of fractures as a fracture is more of surgical concern.

Samford-400 Tablet finds a lot of benefit in treating depression. However, consult your doctor before starting Samford-400 Tablet , and if you are on any anti-depressants, keep your doctor informed to avoid any interactions.

In case you miss a dose of Samford-400 Tablet , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.

Samford-400 Tablet is probably safe on the kidney, however, in case of CKD, it is best to consult your treating doctor before using Samford-400 Tablet .

The active ingredient is S-adenosyl-l-methionine disulfate tosylate, an essential amino acid.

Samford-400 Tablet helps keep your liver healthy. It supports liver function, protects liver cells, and reduces inflammation. Samford-400 Tablet also boosts the production of glutathione, a powerful antioxidant that shields the liver. Studies have shown that Samford-400 Tablet may be beneficial for various liver conditions, including fatty liver disease, fibrosis, and hepatitis. However, it's crucial to consult a healthcare professional before taking Samford-400 Tablet , especially if you have a pre-existing liver condition or are taking medications. They will determine the right dosage and ensure safe use.

Common side effects of Samford-400 Tablet may include nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

Informing your doctor about your medical history is crucial for receiving personalized and effective care. Sharing your previous illnesses, surgeries, current medications, allergies, and family medical history helps your doctor understand your overall health and make informed decisions. This includes identifying potential drug interactions, avoiding harmful side effects, and developing an adapted treatment plan that addresses your unique needs.

Don't take Samford-400 Tablet without consulting a doctor. They will help you determine if it's right for you, ensure the correct dosage, and monitor potential interactions with other medications or health conditions. Taking medication on your own can be risky and lead to adverse reactions or worsening of underlying conditions. Always consult a healthcare professional before taking any medication, including Samford-400 Tablet , to ensure your safety and well-being.

Sharing medication with others, even if they have the same problem, is not a good idea. Everyone's body is different; what works for you might not work for someone else. Plus, it can be dangerous and lead to bad reactions or interactions with other medications. Instead, tell the person to see their own doctor so they can get the right treatment and medication for their specific needs. It's always best to prioritize safety and get personalized medical advice!

It is important to exercise caution when driving or riding a bike after taking Samford-400 Tablet . Samford-400 Tablet can cause dizziness, sleepiness, or lightheadedness, impairing your ability to drive safely. For safety, consult your doctor or the medication's label. They might advise you to wait a bit after taking the Samford-400 Tablet or to have someone else drive or ride with you.

The onset of action may vary depending on the individual and the condition being treated.

Consult your doctor before stopping or changing your medication regimen.

It is not established if Samford-400 Tablet is safe to use in children. Please consult the treating doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Flat No: 302, 3Rd Floor, Nagarjuna Arcade, Sree Colony, Neredmet Cross Roads, Malkajgiri Mandal-500056, Telangana
Other Info - SAM0203

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:57 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.webmd.com/vitamins/ai/ingredientmono-786/same
  2. https://www.drugs.com/npp/same.html
  3. https://www.nccih.nih.gov/health/sadenosyllmethionine-same-in-depth

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