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compositionComposition:ENTECAVIR-0.5MG
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Prescription Medicine
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Samhep-E 0.5 mg Tablet 30's is used to treat chronic hepatitis B virus (HBV) infection. It helps reduce the amount of virus in the body, prevents further liver damage, and supports long-term liver health. With regular use, it lowers the risk of complications such as cirrhosis and liver failure, helping to slow the progression of liver disease.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ENTECAVIR-0.5MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Samhep-E 0.5 mg Tablet 30's

Samhep-E 0.5 mg Tablet 30's is an oral antiviral prescription medication used to treat chronic hepatitis B virus infection in adults and children. It works by lowering the amount of the virus in your body, which helps prevent the infection from causing severe damage to your liver. It is important to know that while this medication helps manage the virus, it is not a cure for hepatitis B.

For Samhep-E 0.5 mg Tablet 30's to work effectively, you must take it consistently at the same time every day. Taking your dose on an empty stomach is highly important, meaning you should take it at least 2 hours after a meal and at least 2 hours before your next meal. Making healthy lifestyle choices, such as eating a balanced diet and avoiding alcohol, can also support your liver health while using this treatment.

While taking Samhep-E 0.5 mg Tablet 30's, some people may experience mild side effects like headaches, fatigue, dizziness, or nausea. However, you must contact your doctor immediately if you experience signs of rare but serious conditions, such as lactic acid buildup in your blood or worsening liver symptoms. Your healthcare team is always your best resource if you notice any unusual physical changes.

Do not take this medicine if you are allergic to any of its ingredients. Before starting Samhep-E 0.5 mg Tablet 30's, tell your doctor if you have kidney disease, as your dose may need to be adjusted. It is also vital to be tested for HIV before starting this medication; taking Samhep-E 0.5 mg Tablet 30's if you have untreated HIV can make the HIV virus much harder to treat in the future.

Certain medications can interact with Samhep-E 0.5 mg Tablet 30's, especially those that affect how your kidneys filter waste. Additionally, you should consult your doctor or pharmacist if you are pregnant, planning to become pregnant, breastfeeding, or if you are caring for an elderly patient, to ensure this medication is safe for your specific situation.

Uses of Samhep-E 0.5 mg Tablet 30's

Samhep-E 0.5 mg Tablet 30's is used in the treatment of chronic (long-term) hepatitis B virus (HBV) infection. The detailed uses of Samhep-E 0.5 mg Tablet 30's are as follows:

  • Chronic HBV Infection: Samhep-E 0.5 mg Tablet 30's is prescribed to manage long-term hepatitis B infections. It helps by slowing down the multiplication of the virus, which protects the liver from progressive damage and scarring.

Key Benefits

Samhep-E 0.5 mg Tablet 30's helps treat chronic hepatitis B infection by reducing the amount of virus in the body and protecting your liver from ongoing damage. Although it is not a cure for hepatitis B, it can help keep the infection under control, improve liver health, and lower the risk of serious liver-related complications.

Benefits may include:

  • Helps reduce the amount of hepatitis B virus in the body.
  • Supports healthy liver function by limiting ongoing liver damage.
  • Reduces the risk of complications such as cirrhosis and liver failure.
  • Helps lower the risk of disease progression associated with chronic hepatitis B.
  • Provides effective long-term control of chronic hepatitis B infection when taken as prescribed.
Side effects of Samhep-E 0.5 mg Tablet
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Eat a well-balanced diet, and avoid highly processed foods.
  • Regular exercise can help prevent ascites.
  • Maintain a healthy weight, as obesity is a risk factor for ascites.
  • Limit salt intake; try to consume no more than 2,000–4,000 milligrams of salt per day.
  • Avoid alcohol, as it can damage your liver and increase the risk of cirrhosis.
  • Practice safe sex, unprotected sex can lead to hepatitis, which can damage the liver and cause cirrhosis.
  • Get vaccinated for diseases like hepatitis, influenza, and pneumococcal.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Take Samhep-E 0.5 mg Tablet 30's on an empty stomach. This means taking your dose at least 2 hours after eating a meal and at least 2 hours before your next meal.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • Take your dose at the same time every day to keep a steady level of the medicine in your body.
  • Always follow your doctor's exact instructions regarding your treatment. Never stop taking this medicine without speaking to your doctor first, as stopping can cause your hepatitis infection to suddenly flare up and worsen.

How Samhep-E 0.5 mg Tablet 30's Works

Samhep-E 0.5 mg Tablet 30's contains Entecavir, a nucleoside analogue. It works by blocking a specific enzyme in your body that the hepatitis B virus needs to replicate its DNA and make copies of itself. By interfering with this copying process, the medicine stops the virus from multiplying. This lowers the amount of virus in your body, allowing your immune system to better manage the infection and reducing active inflammation in your liver.
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Alcohol

Consult your doctor

The interaction of alcohol with Samhep-E 0.5 mg Tablet 30's is unknown. Please consult a doctor before consuming alcohol while using Samhep-E 0.5 mg Tablet 30's.

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Pregnancy

Caution

Samhep-E 0.5 mg Tablet 30's is a category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Samhep-E 0.5 mg Tablet 30's is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Samhep-E 0.5 mg Tablet 30's may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy, drowsy or tired after taking Samhep-E 0.5 mg Tablet 30's.

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Liver

Caution

Take Samhep-E 0.5 mg Tablet 30's with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required. Please consult a doctor.

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Kidney

Caution

Take Samhep-E 0.5 mg Tablet 30's with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required. Please consult a doctor.

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Children

Caution

Samhep-E 0.5 mg Tablet 30's is not recommended for children below 2 years or weighing less than 10 kg. However, in children above 2 years, Samhep-E 0.5 mg Tablet 30's should be used with caution and doses prescribed by a doctor.

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Heart

Safe if prescribed

Samhep-E 0.5 mg Tablet 30's is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Samhep-E 0.5 mg Tablet 30's should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Samhep-E 0.5 mg Tablet 30's.

What if I have taken an overdose of Samhep-E 0.5 mg Tablet 30's

If you suspect an overdose or if someone has accidentally taken too much of this medication, seek immediate emergency medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Avoid alcohol completely: Alcohol causes extra strain on your liver and can speed up liver damage, making it harder for your treatment to work safely.
  • Eat a liver-friendly diet: Focus on whole foods, including fresh fruits, vegetables, lean proteins, and whole grains. Limit foods high in saturated fats, sugar, and processed ingredients.
  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys efficiently process and clear the medication from your body.
  • Avoid self-medicating with supplements: Do not take any herbal remedies, vitamins, or liver detox supplements without asking your pharmacist or doctor first, as some can cause direct liver toxicity.
  • Practice safe habits: Remember that hepatitis B can spread through contact with infected blood or bodily fluids. Avoid sharing personal items like razors or toothbrushes, and use barrier protection during sexual activity to protect others.
health query

Have a query?

How Soon It Starts Working

  • The time required for Samhep-E 0.5 mg Tablet 30's to start to work: The time required for Samhep-E 0.5 mg Tablet 30's to show its action is unknown.
  • The time for which the effects of Samhep-E 0.5 mg Tablet 30's last: The duration of action for Samhep-E 0.5 mg Tablet 30's is unknown.

What if you forget to take Samhep-E 0.5 mg Tablet 30's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular routine. Do not take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Never stop taking this medicine abruptly: Stopping your treatment suddenly can cause a severe, life-threatening flare-up of your hepatitis B infection.
  • Get regular blood tests: You must visit your doctor for regular blood tests to check your liver function and monitor how well the medicine is working.
  • Get tested for HIV: Ensure you are tested for HIV before starting Samhep-E 0.5 mg Tablet 30's. If you have untreated HIV, taking this drug can cause the HIV virus to become resistant to standard HIV treatments.
  • Watch your kidney health: Tell your doctor if you have kidney problems, as you may need a lower dose or a modified dosing schedule.
  • Set a daily reminder: Because this medicine must be taken on an empty stomach, setting a daily phone alarm can help you maintain a safe, consistent routine.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction:

  • Medicines That May Reduce Kidney Function (e.g., cyclosporine, tacrolimus, gentamicin, amikacin, vancomycin): Taking these medicines alongside Samhep-E 0.5 mg Tablet 30's may slow the removal of Samhep-E 0.5 mg Tablet 30's from the body and increase the risk of side effects.

Drug-Food Interaction:

  • Food: Consuming food while taking Samhep-E 0.5 mg Tablet 30's may reduce the amount of medicine absorbed, making it less effective. Take Samhep-E 0.5 mg Tablet 30's on an empty stomach, at least 2 hours before or 2 hours after a meal.

Drug-Disease Interaction:

  • Kidney Disease: Because this medicine is cleared by the kidneys, decreased kidney function can cause the drug to build up to unsafe levels in the blood. Your doctor may need to adjust your dose.
  • HIV Infection: If you have undiagnosed or untreated HIV, taking Samhep-E 0.5 mg Tablet 30's can lead to the HIV virus developing resistance to similar antiviral medications, making future HIV treatment much more difficult.
EntecavirAllopurinol
Severe
EntecavirMethotrexate
Severe

Drug-Drug Interactions

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EntecavirAllopurinol
Severe
How does the drug interact with Samhep-E 0.5 mg Tablet:
Coadministration of Allopurinol with Samhep-E 0.5 mg Tablet may increase the blood levels of one or both medicines and increase side effects.

How to manage the interaction:
If you are supposed to take Allopurinol and Samhep-E 0.5 mg Tablet together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience increased side effects, contact your doctor.
EntecavirMethotrexate
Severe
How does the drug interact with Samhep-E 0.5 mg Tablet:
The combined use of Samhep-E 0.5 mg Tablet with methotrexate may increase levels of Samhep-E 0.5 mg Tablet, and increase the risk or severity of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Samhep-E 0.5 mg Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult a doctor. Do not stop using any medications without consulting a doctor.
EntecavirCiprofloxacin
Severe
How does the drug interact with Samhep-E 0.5 mg Tablet:
Combining Samhep-E 0.5 mg Tablet with ciprofloxacin may result in higher blood levels of one or both the medications.

How to manage the interaction:
Although taking ciprofloxacin and Samhep-E 0.5 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. If your situation changes or you start to notice more side effects, consult your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

Samhep-E 0.5 mg Tablet 30's is used to treat chronic hepatitis B virus (HBV) infection.
Samhep-E 0.5 mg Tablet 30's contains Entecavir, an antiviral drug that works by preventing viral DNA polymerase enzyme action in the liver cells, which is essential for the virus to multiply. Therefore, it prevents the virus from replicating and reduces the amount of hepatitis B virus in the body.
Yes, hepatitis B virus infection is highly contagious and spreads from one person to another. Therefore, it is recommended to avoid sharing personal items or needles containing an infected person's blood or body fluids.
Samhep-E 0.5 mg Tablet 30's may cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are very obese. However, if you experience stomach pain, vomiting or nausea while taking Samhep-E 0.5 mg Tablet 30's, please consult a doctor immediately.
You are not recommended to take Samhep-E 0.5 mg Tablet 30's with celecoxib (painkiller), as it may increase the blood levels of Samhep-E 0.5 mg Tablet 30's, leading to more adverse effects and may also affect kidney function. However, please consult your doctor before taking Samhep-E 0.5 mg Tablet 30's with other medicines.
Samhep-E 0.5 mg Tablet 30's does not cure hepatitis B virus infection. Samhep-E 0.5 mg Tablet 30's reduces the amount of hepatitis B virus in the body and improves liver functioning by decreasing liver damage.
Samhep-E 0.5 mg Tablet 30's is not recommended for hepatitis B patients with HIV infection unless they are taking medicines to treat HIV infection at the same time, as Samhep-E 0.5 mg Tablet 30's may cause HIV infection to become resistant to certain HIV drugs and reduce their effectiveness. Therefore, it is advised to get tested for HIV infection before taking Samhep-E 0.5 mg Tablet 30's.
You are not recommended to stop taking Samhep-E 0.5 mg Tablet 30's without consulting your doctor, as it may worsen the infection or cause recurring symptoms. Therefore, take Samhep-E 0.5 mg Tablet 30's for as long as your doctor has prescribed it. If you experience any difficulty while taking Samhep-E 0.5 mg Tablet 30's, please consult your doctor.
Samhep-E 0.5 mg Tablet 30's may cause side effects like dizziness, headache, nausea, vomiting, drowsiness, extreme tiredness, inability to sleep, diarrhoea, or indigestion. Most of these side effects do not require medical attention. However, if the side effects worsen, please consult your doctor.
Food significantly lowers the amount of medicine your body can absorb, making the treatment less effective. Taking it on an empty stomach ensures you receive the full therapeutic benefit. Talk to your doctor or pharmacist if you have trouble scheduling your doses.
Severe stomach pain, especially when accompanied by nausea, vomiting, or deep breathing, can be a sign of a serious condition called lactic acidosis or worsening liver issues. You should contact your doctor or seek emergency medical care immediately.
The safety of this medicine during pregnancy has not been fully established. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor to carefully weigh the risks and benefits for you and your baby.
No, taking this medicine does not prevent the spread of hepatitis B through sexual contact or blood exposure. You must continue to practice safe sex and avoid sharing personal items like needles or razors. Talk to your doctor about how to keep your loved ones safe.
Treatment for chronic hepatitis B is usually long-term and often lasts for several years or even indefinitely. Your doctor will monitor your blood tests regularly to determine how long you need to stay on the medication. Talk to your doctor if you have questions about the duration of your treatment.

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Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - SAM0249
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