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compositionComposition:S ADENOSYL L METHIONINE DISULFATE TOSYLATE-400MG
prescriptionPrescription Medicine
Samivio Tablet 10's
Samivio Tablet 10's
Samivio Tablet 10's

Samivio Tablet is an amino acid used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. It is a nutritional supplement that helps in optimal cellular functioning, monitors and regulates important physiological functions, and increases glutathione concentration and metabolism of the liver. It may be used to improve joint function and lessen discomfort and inflammation associated with osteoarthritis.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

S ADENOSYL L METHIONINE DISULFATE TOSYLATE-400MG

Manufacturer/Marketer :

Wellvio Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Samivio Tablet

Samivio Tablet is used to treat moderate alcoholic liver disease, osteoarthritis (a condition in which the joints are affected), and depression (a psychological experience that affects the way we think, the things we do and the way we act). Alcoholic liver disease occurs due to liver damage because of excessive alcohol consumption.

Samivio Tablet contains S-Adenosyl-L-Methionine disulfate tosylate. It is an essential amino acid required for optimal cellular functioning. Samivio Tablet is believed to monitor and regulate important physiological functions in living cells.

Samivio Tablet may cause common side effects such as nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Discuss your entire medical and medication history with your treating doctor and keep them informed of any pending surgical procedure.

Uses of Samivio Tablet

Samivio Tablet used in the treatment of liver disease, osteoarthritis, and depression. The detailed uses of Samivio Tablet are as follows:

  • Liver Disease: Samivio Tablet supports liver health by promoting liver cell regeneration and reducing inflammation, helping alleviate symptoms of liver disease.
  • Osteoarthritis: Samivio Tablet helps in the management of osteoarthritis by reducing pain and inflammation, improving joint health.
  • Depression: Samivio Tablet may help to improve depressive symptoms, supporting mental health and well-being.

Health Queries

In which conditions should Liv.52 be used?

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Liv.52 is used to support liver health and is generally recommended in conditions where the liver is under stress or impaired. These include fatty liver disease, liver enlargement, liver inflammation, alcohol-related liver stress, and mild liver dysfunction due to medications or infections. It may also be used as a supportive therapy to improve appetite and digestion in patients with liver disorders. You should consult your doctor before using Liv.52, as they can evaluate your liver condition and determine whether it is appropriate for your specific situation.

Can taking calcium tablets worsen symptoms of gallbladder stones in a patient with fatty liver and unilateral pedal oedema?

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Calcium supplements are not typically known to worsen gallbladder stones directly. However, in some individuals, calcium, especially in high doses, can contribute to constipation or gastrointestinal discomfort, which may aggravate abdominal symptoms in patients with gallbladder disease. In someone with fatty liver and unilateral pedal oedema, it is essential to first evaluate the cause of the swelling and overall liver and kidney function before starting supplements. You should consult your doctor before taking calcium tablets, as they can assess your liver, kidney, and gallbladder status and advise the safest dosage or alternative options based on your specific condition.

Why am I often tired and have no appetite due to liver disease?

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Why am I often tired and have no appetite due to liver disease?

What can help in recovery from liver disease after surgery, especially if I have constant watery eyes?

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Recovery after liver surgery requires close follow-up with your doctor, who will guide you based on your specific condition and test results. Supporting your liver includes following medical advice, maintaining a balanced diet, avoiding alcohol and substances that can harm the liver, and managing other health conditions. Constant watery eyes may be related to medications, infections, or other health issues, so it is essential to mention this to your doctor, who can evaluate the cause and suggest appropriate care. Regular monitoring, rest, and timely medical guidance are critical to a safe and effective recovery.

What are the treatment options for fatty liver disease with an enlarged liver?

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Treatment for fatty liver disease focuses on lifestyle changes and managing other health conditions. Key steps include losing excess weight gradually through a balanced diet and regular exercise, avoiding alcohol, and managing conditions such as diabetes, high cholesterol, and high blood pressure. Eating a low-fat, low-sugar diet with plenty of fruits, vegetables, and whole grains helps reduce liver fat. Regular monitoring of liver function is important. In some cases, doctors may recommend medicines to manage related conditions, but there is no specific drug that can cure fatty liver. Consistent lifestyle changes are the most effective way to reduce liver enlargement and prevent further liver damage.

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Directions for Use

  • Samivio Tablet can be taken with or without food as advised by the doctor.
  • Strictly follow your doctor's recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow Samivio Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

  • Promotes liver health: Helps in protecting liver cells from harm brought on by alcohol, pollutants, fatty liver, and some medications.
  • Enhances bile flow: Helps with cholestasis by encouraging the production of bile and lowering symptoms like jaundice and itching.
  • Antioxidant effect: Raises glutathione levels, which aid in detoxifying toxic chemicals and lowering oxidative stress.
  • Reduces joint discomfort: This may assist improve joint function and alleviate osteoarthritis pain, stiffness, and inflammation.
  • Boosts energy and metabolism: Promotes healthy metabolic and cellular functions.
  • Neuroprotective action: Promotes brain health and helps shield nerve cells.

How Samivio Tablet Works

Samivio Tablet contains S-Adenosyl-L-Methionine disulfate tosylate. It is an essential amino acid required for optimal cellular functioning. Samivio Tablet is believed to monitor and regulate important physiological functions in living cells. It increases glutathione concentration and metabolism of the liver. Samivio Tablet increases chondrocyte proteoglycan synthesis, thereby helping treat osteoarthritis.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Samivio Tablet

Do not take more than the suggested dose of Samivio Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • It is advisable to inform the doctor if you are allergic to any component of Samivio Tablet .
  • Keep your doctor informed of your entire medical history before using Samivio Tablet .
  • Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding.
  • Exercise caution when taking Samivio Tablet with any anti-Parkinsonian drugs or antidepressants.
  • It is not advisable to take Samivio Tablet with alcohol as there may be an interaction.
  • Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Diet & Lifestyle Advise

Diet:

  • Consume a diet that supports liver detoxification and general health by include fresh fruits, green leafy vegetables, whole grains, and foods high in fiber.
  • Try to eat lean proteins such as pulses, beans, seafood, eggs, and low-fat dairy.
  • To avoid fat buildup in the liver, consume fewer processed, junk, and greasy foods.
  • Maintain proper hydration by drinking lots of water and adding liquids like fresh juice and coconut water to aid in body processes and detoxification.

Lifestyle changes:

  • To enhance liver function and overall health, engage in moderate exercise for at least 30 minutes a day, such as walking, yoga, or cycling.
  • Avoid alcohol and tobacco, as these can damage the liver and lessen the medication's effects.
  • To prevent fatty liver and enhance treatment effectiveness, consume a balanced diet and lead an active lifestyle.

Stress management:

  • To lower anxiety and elevate mood, practice yoga, deep breathing, or meditation on a regular basis.
  • To promote mental and emotional health, aim for 7 to 8 hours of good sleep every day.
  • To reduce stress and emotional strain, spend time with loved ones and express your emotions.

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

All Substitutes & Brand Comparisons

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Alcohol

Consult your doctor

It is not known whether it is safe to consume alcohol with Samivio Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Consult your doctor

Please consult your doctor before taking Samivio Tablet if you are pregnant.

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Breast Feeding

Consult your doctor

Please consult your doctor before taking Samivio Tablet if you are breastfeeding.

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Driving

Caution

Samivio Tablet may rarely cause drowsiness and dizziness. Exercise caution while driving in case of these side effects.

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Liver

Consult your doctor

Samivio Tablet is possibly safe on the liver. Please consult your doctor if you have any concerns.

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Kidney

Consult your doctor

Samivio Tablet is possibly safe on the kidney. Please consult your doctor if you have any concerns.

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Children

Consult your doctor

It is not established whether Samivio Tablet is safe for children. Please consult the treating doctor if you have any concerns.

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Heart

Consult your doctor

Samivio Tablet is generally considered safe for heart patients when taken at the recommended dose. However, please consult your doctor if you have any concerns.

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Geriatrics

Consult your doctor

Samivio Tablet should be given to elderly patients only if recommended by a doctor. Consult your healthcare professional for guidance.

FAQs

Samivio Tablet is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression.

Samivio Tablet works by synthesising methionine, an essential amino acid required for cellular energy.

Please see an orthopaedic doctor if you have had a fracture. Samivio Tablet is used in the treatment of arthritis and has limited use in fractures, as fractures are more of a surgical concern.

Samivio Tablet finds a lot of benefit in treating depression. However, consult your doctor before starting Samivio Tablet , and if you are on any anti-depressants, keep your doctor informed to avoid any interactions.

In case you miss a dose of Samivio Tablet , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.

Samivio Tablet is probably safe for the kidneys; however, if you have CKD, it is best to consult your treating doctor before using Samivio Tablet .

The active ingredient is S-adenosyl-l-methionine disulfate tosylate, an essential amino acid.

Samivio Tablet helps keep your liver healthy. It supports liver function, protects liver cells, and reduces inflammation. Samivio Tablet also boosts glutathione production, a powerful antioxidant that protects the liver. Studies have shown that Samivio Tablet may be beneficial for various liver conditions, including fatty liver disease, fibrosis, and hepatitis. However, it's crucial to consult a healthcare professional before taking Samivio Tablet , especially if you have a pre-existing liver condition or are taking medications. They will determine the right dosage and ensure safe use.

Common side effects of Samivio Tablet may include nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

Informing your doctor about your medical history is crucial for receiving personalised and effective care. Sharing your past illnesses and surgeries, current medications, allergies, and family medical history helps your doctor understand your overall health and make informed decisions. This includes identifying potential drug interactions, avoiding harmful side effects, and developing an adapted treatment plan that addresses your unique needs.

Don't take Samivio Tablet without consulting a doctor. They will help you determine if it's right for you, ensure the correct dosage, and monitor potential interactions with other medications or health conditions. Taking medication on your own can be risky and lead to adverse reactions or worsening of underlying conditions. Always consult a healthcare professional before taking any medication, including Samivio Tablet , to ensure your safety and well-being.

It is important to exercise caution when driving or riding a bike after taking Samivio Tablet . Samivio Tablet can cause dizziness, sleepiness, or lightheadedness, impairing your ability to drive safely. For safety, consult your doctor or the medication's label. They might advise you to wait a bit after taking the Samivio Tablet or to have someone else drive or ride with you.

The onset of action may vary depending on the individual and the condition being treated.

Consult your doctor before stopping or changing your medication regimen.

It is not established whether Samivio Tablet is safe for children. Please consult the treating doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

730 JMD Megapolis Sohna Road Gurugram 122018
Other Info - SAM0146

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Feb 26, 2026 | 8:59 AM IST

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