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compositionComposition:OCTREOTIDE-100MCG
prescription
Prescription Medicine
info
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Sandostatin Lar 10Mg Inj is used to treat acromegaly (abnormal growth of the feet, hands, and face). It is also used to control diarrhoea and flushing caused by carcinoid tumours. It contains Octreotide which works by reducing the amounts of certain natural substances produced by the body. This medicine may sometimes cause side effects such as abdominal pain, constipation, nausea, headache, flatulence, and injection site reactions. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OCTREOTIDE-100MCG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Sandostatin Lar 10Mg Inj

Sandostatin Lar 10Mg Inj is a prescription injectable medication used to manage severe watery diarrhoea and sudden flushing associated with certain types of cancerous tumours, such as carcinoid tumours. It is also prescribed to reduce the levels of growth hormone in people with acromegaly, a condition where the body produces too much growth hormone. By mimicking a natural hormone in your body, it helps bring these symptoms under control.

To get the most benefit, you must use Sandostatin Lar 10Mg Inj consistently and exactly as prescribed by your doctor. This medicine is given as an injection, and injecting it between meals or at bedtime can help reduce common stomach-related side effects. Making simple changes, such as eating smaller, more frequent meals and staying well-hydrated, can also support your treatment and ease digestive symptoms.

While using Sandostatin Lar 10Mg Inj, you may experience mild side effects like pain at the injection site, nausea, or stomach gas. However, you should contact your doctor immediately if you notice signs of gallstones, such as sudden and severe pain in your upper right stomach, or if you experience a very slow heart rate (an unusually slow heartbeat).

Before starting this medication, tell your doctor if you have a history of gallbladder disease, kidney problems, liver damage, or diabetes. Do not take this if you have a known allergy to this medicine or any of its inactive ingredients.

This medicine can interact with other drugs like insulin or beta-blockers, which may require your doctor to adjust your doses to prevent abnormal blood sugar or heart rate levels. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to ensure this treatment is safe for your specific situation.

Uses of Sandostatin Lar 10Mg Inj

Sandostatin Lar 10Mg Inj used in the treatment of acromegaly and severe diarrhoea associated with tumours. The detailed uses of Sandostatin Lar 10Mg Inj are as follows:

  • Acromegaly: Sandostatin Lar 10Mg Inj helps by lowering the excess levels of growth hormone and insulin-like growth factor 1 (IGF-1), a hormone involved in body growth, which relieves symptoms like enlarged hands, feet, and facial features.
  • Severe diarrhoea and flushing from carcinoid tumours: Sandostatin Lar 10Mg Inj targets and controls the severe watery diarrhoea and intense skin flushing caused by these hormone-producing tumours.
  • Watery diarrhoea from vasoactive intestinal peptide (VIP) tumours (tumours that release a hormone causing severe diarrhoea): Sandostatin Lar 10Mg Inj reduces the amount of water and salts released into the gut, helping control life-threatening diarrhoea.

Key Benefits

Sandostatin Lar 10Mg Inj helps reduce troublesome symptoms such as severe diarrhoea, flushing, and other hormone-related problems while supporting better long-term health. Some of the benefits of this medication are:

  • Helps control severe, frequent diarrhoea, reducing the risk of dehydration.
  • Relieves flushing episodes, making daily activities more comfortable.
  • Reduces the anxiety and inconvenience caused by unpredictable bowel movements.
  • Keeps growth hormone levels within a healthy range in people with growth hormone disorders.
  • Helps reduce symptoms such as joint pain, headaches, and excessive sweating associated with high growth hormone levels.
  • Lowers the risk of long-term complications related to uncontrolled hormone production.
Side effects of Sandostatin Lar 10Mg Inj
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Exercise regularly and maintain a healthy weight.
  • Manage cholesterol and blood pressure.
  • Limit intake of caffeine and alcohol.
  • Avoid vaping and tobacco smoke.
  • Get enough sleep.
  • Talk to your doctor about antiarrhythmic drugs or other medications to treat your condition.

Directions for Use

  • Sandostatin Lar 10Mg Inj is administered either under the skin (subcutaneously) or through an IV infusion (intravenously), depending on your medical condition.
  • It is usually administered three times daily or as prescribed by your doctor.
  • Your doctor or nurse will administer your first dose of Sandostatin Lar 10Mg Inj under the skin and may instruct you on self-administration. However, IV infusion will only be done by a healthcare professional.

How Sandostatin Lar 10Mg Inj Works

Sandostatin Lar 10Mg Inj works by mimicking the actions of somatostatin, a hormone that naturally occurs in your body. Somatostatin acts as a chemical brake, slowing down the release of several other hormones and digestive juices. When you inject Sandostatin Lar 10Mg Inj, it binds to specific receptors in your body to block the abnormal, excessive release of growth hormone and thyroid-stimulating hormone. In the digestive tract, it slows down gut movement, reduces blood flow to the organs, and reduces the amount of water and salts released into the gut. This dual action effectively stops severe diarrhoea and shrinks the hormone levels responsible for abnormal tissue growth.
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Alcohol

Caution

It is not known that Sandostatin Lar 10Mg Inj may interact with alcohol. Therefore, avoid drinking alcohol while using Sandostatin Lar 10Mg Inj.

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Pregnancy

Caution

Sandostatin Lar 10Mg Inj should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Caution

It is not known that Sandostatin Lar 10Mg Inj may pass into breast milk. Hence, inform your doctor before taking Sandostatin Lar 10Mg Inj.

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Driving

Caution

Sandostatin Lar 10Mg Inj has negligible effects on the ability to drive and use machines. However, you may experience some side effects like tiredness and headache that may reduce your ability to drive.

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Liver

Caution

Sandostatin Lar 10Mg Inj to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Sandostatin Lar 10Mg Inj to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Sandostatin Lar 10Mg Inj should not be used for children below the age of 18 years as it is not approved for children.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Sandostatin Lar 10Mg Inj. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Sandostatin Lar 10Mg Inj in elderly patients. Please consult your doctor.

What if I have taken an overdose of Sandostatin Lar 10Mg Inj

In case of an accidental overdose, seek immediate medical attention or contact a poison control centre. Symptoms of an overdose may include severe nausea, sudden drops in blood sugar, a very slow heart rate, or temporary numbness.

Diet & Lifestyle Advise

  • Eat small, frequent meals: Consuming smaller portions throughout the day can ease digestion and reduce the bloating and gas often associated with this medication.
  • Stay well-hydrated: If you are managing severe diarrhoea, drink plenty of electrolyte-rich fluids (such as broth or oral rehydration solutions) to prevent dehydration.
  • Limit high-fat foods: High-fat meals can worsen the greasy stools and digestive discomfort that some people experience while using Sandostatin Lar 10Mg Inj.
  • Monitor your blood sugar: Since this medicine can cause fluctuations in blood sugar, check your glucose levels regularly if you have diabetes, and keep a log for your doctor.
  • Get regular health check-ups: Because long-term use can lead to gallstones and affect hormone levels or heart rhythm, attend all scheduled appointments. Your doctor may recommend gallbladder ultrasound, blood sugar monitoring, thyroid function tests, and heart tests, such as an ECG (electrocardiogram), when needed.
health query

Have a query?

How Soon It Starts Working

The time required for Sandostatin Lar 10Mg Inj to start to work: Sandostatin Lar 10Mg Inj ideally shows its action within 30 minutes after administration The time for which the effects of Sandostatin Lar 10Mg Inj last: The effect of Sandostatin Lar 10Mg Inj lasts for 12 hours.

What if you forget to take Sandostatin Lar 10Mg Inj

If you miss a dose, inject it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not inject a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure what to do.

Storage

•
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Always inspect the liquid: Check the vial or syringe before use. If you see any cloudiness, discolouration, or floating particles, do not inject it and use a new vial instead.
  • Rotate injection sites: Never inject into the exact same spot twice in a row. Rotate between your thighs, abdomen, and upper arms to keep your skin healthy.
  • Never reuse needles: Use a sterile needle and syringe for every single injection to prevent serious infections.
  • Do not shake the vial: Gently swirl the vial if needed, but shaking can damage the medication and render it less effective.
  • Check your pulse: Since this medicine can slow your heart rate, report any feelings of dizziness, lightheadedness, or unusually slow heartbeats to your doctor.
  • Allergy warning: Do not use Sandostatin Lar 10Mg Inj if you are allergic to Sandostatin Lar 10Mg Inj or any of the ingredients in this medicine. Tell your doctor if you have ever had a severe allergic reaction after using Sandostatin Lar 10Mg Inj.

Drug-Drug Interactions

verifiedApollotooltip
  • Insulin and oral diabetes medicines: Sandostatin Lar 10Mg Inj can alter your blood sugar levels, which may increase the risk of low blood sugar. Your doctor may need to adjust your diabetes medication doses.
  • Heart medicines (e.g., Metoprolol, Verapamil): Combining these medicines with Sandostatin Lar 10Mg Inj can cause your heart rate to drop to dangerously low levels.
  • Immunosuppressants (e.g., Cyclosporine): Sandostatin Lar 10Mg Inj can lower the amount of cyclosporine in your blood, making it less effective. Your doctor may need to monitor your cyclosporine levels closely.
  • Medications that mimic the action of dopamine (e.g., Bromocriptine): Sandostatin Lar 10Mg Inj can increase the absorption of bromocriptine, which may require a dose adjustment of that medication.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Sandostatin Lar 10Mg Inj has no known clinically significant interactions with food or drinks.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Yes. Sandostatin Lar 10Mg Inj can affect blood sugar levels by altering the release of insulin and glucagon, which may cause either high or low blood sugar. If you have diabetes, monitor your blood glucose closely, and your doctor may need to adjust your diabetes medicines during treatment. Regular blood sugar monitoring is recommended.
Store Sandostatin Lar 10Mg Inj in a refrigerator at 2°C to 8°C and do not freeze it. If necessary, it may be kept at room temperature (below 25°C) for up to 14 days, provided it is protected from light. After this period, any unused medicine should be discarded. Follow your doctor's or pharmacist's storage instructions.
Sandostatin Lar 10Mg Inj is injected under the skin (subcutaneously) or sometimes into a muscle (intramuscularly). Your healthcare provider will show you how to properly prepare and inject the medicine yourself. Talk to your doctor if you have questions about the injection technique.
The safety of Sandostatin Lar 10Mg Inj during pregnancy and breastfeeding is not fully established. It should only be used if the potential benefits outweigh the risks. Talk to your doctor to discuss your options.
This medicine slows down the movement of your digestive system and can temporarily reduce your body's ability to absorb dietary fats. This can cause bloating, gas, or nausea, which usually improves over time. Talk to your doctor if these symptoms persist.
Yes, long-term use of Sandostatin Lar 10Mg Inj can slow gallbladder activity, which increases the risk of developing gallstones. Your doctor may recommend regular ultrasound scans of your gallbladder during treatment. Talk to your doctor if you experience sudden upper stomach pain.
No, Sandostatin Lar 10Mg Inj does not cure these conditions. Instead, it helps manage and control the symptoms by regulating excess hormone levels in your body. Talk to your doctor about your long-term treatment goals.
To minimise pain, allow the medication to sit at room temperature for 20 to 30 minutes before injecting. Additionally, avoid injecting into the same spot repeatedly and rotate sites daily. Talk to your doctor or pharmacist if the pain is severe or does not go away.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Octreotide Oral Injection Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.7825 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. emc Octreotide. [[Accessed on 26.Aug].2019]Check here
  4. R Chaudhary, Balwinder Singh and P Subhas. Octreotide in Gastroenterology. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2017. [Accessed on 7th June 2022].Check here
  5. Sun Pharmaceutical Industries Europe B.V. Electronic Medicines Compendium (EMC). [Revised in June 2022] [Accessed on 7th June 2022].Check here
  6. novartis Octreotide. [[Accessed on 26.Aug].2019]Check here
  7. Novartis Pharmaceuticals. Efficay/Safety of Octreotide Acetate in Patients with Uncontrolled Acromegaly. NIH U.S. National Library of Medicine. ClinicalTrials.gov. [Revised in May 2011] [Accessed on 7th June 2022].Check here

Country of origin

United Kingdom

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - SAN0074
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