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  3. Satrogyl O Tablet 10's

Satrogyl O Tablet 10's, Pack of 10 TABLETS
Satrogyl O Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Satrogyl O Tablet is used to treat diarrhoea and dysentery. It helps treat bacterial infections, including intra-abdominal infection, gynaecological and pelvic infections, foot ulcers in diabetes, post-operative infections, dental infections, and infections in immunocompromised patients. It contains two antibiotic medicines, namely: Ofloxacin and Satranidazole, which kill harmful bacteria and parasites (amoebae). In some cases, it may cause side effects such as nausea, vomiting, stomach pain, loss of appetite, dizziness, and headaches. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

OFLOXACIN-200MG + SATRANIDAZOLE-300MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Satrogyl O Tablet

Satrogyl O Tablet belongs to the class of ‘antibiotics’, primarily used to treat diarrhoea and dysentery. It helps treat bacterial infections, including intra-abdominal infection, gynaecological and pelvic infections, foot ulcers in diabetes, post-operative infections, dental infections, and infections in immunocompromised patients. Diarrhoea is a condition that causes the frequent passing of loose or watery stools. Dysentery is an intestinal inflammation that leads to severe diarrhoea accompanied by mucus or blood in the stools. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body.

Satrogyl O Tablet contains two antibiotic medicines, namely: Ofloxacin and Satranidazole. Ofloxacin belongs to a class of antibiotics known as quinolones. It works by inhibiting bacterial DNA gyrase, an enzyme required for replicating, transcribing, and repairing DNA. Satranidazole is an anti-amoebic, antiprotozoal, and antibacterial medicine that treats various infections caused by bacteria and parasites (amoebas). It is bactericidal, killing harmful bacteria and parasites (such as amoebas) by damaging their DNA. It prevents the division of bacterial cells and inhibits the repair of bacterial cells.

Please take Satrogyl O Tablet in the dose and duration prescribed by your doctor based on your medical condition. Satrogyl O Tablet is generally safe to use. However, some individuals may experience side effects such as nausea, vomiting, stomach pain, loss of appetite, dizziness, and headaches. Most of these side effects of Satrogyl O Tablet do not require medical attention and typically resolve on their own over time. If these side effects persist longer, please consult your doctor.

If you are allergic to Satrogyl O Tablet or any other medicines, please tell your doctor. Do not suddenly stop this medicine to avoid unpleasant side effects and sudden withdrawal symptoms. Intake of probiotics, prebiotics, and plenty of fluids is recommended if you suffer from dysentery and diarrhoea. Do not drive or operate heavy machinery after taking Satrogyl O Tablet as it may cause dizziness. Please try avoiding alcoholic beverages during your treatment, as they can cause flushing and a general sick feeling. Pregnant and breastfeeding women should use Satrogyl O Tablet with proper consultation and caution.

Uses of Satrogyl O Tablet

Satrogyl O Tablet is used in the treatment of diarrhoea and dysentery. The detailed uses of Satrogyl O Tablet are as follows:<br/>• Treats bacterial diarrhoea: Satrogyl O Tablet helps eliminate harmful bacteria in the intestines that cause loose and watery stools.<br/>• Manages amoebic dysentery: Satrogyl O Tablet is effective against protozoal infections that cause bloody stools, abdominal cramps, and persistent diarrhoea.<br/>• Controls mixed infections: Satrogyl O Tablet treats gastrointestinal infections involving both bacteria and protozoa, providing broad-spectrum antimicrobial action.<br/>

Directions for Use

  • Satrogyl O Tablet can be taken with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Satrogyl O Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Satrogyl O Tablet contains two antibiotic medicines, namely: Ofloxacin and Satranidazole. Ofloxacin is a quinolone antibiotic that inhibits bacterial DNA gyrase, an enzyme required for replicating, transcription, and repairing the DNA. Satranidazole is an anti-amoebic, antiprotozoal, and antibacterial medicine effective against a wide range of gram-positive and gram-negative bacteria. It kills the harmful anaerobic bacteria and certain anaerobic protozoa (Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia), causing diarrhoea. It is bactericidal, killing harmful bacteria and parasites (such as amoebas) by damaging their DNA. It also prevents the division of bacterial cells and inhibits the repair of bacterial cells.

How Satrogyl O Tablet Works

Satrogyl O Tablet contains two antibiotic medicines, namely: Ofloxacin and Satranidazole. Ofloxacin belongs to a class of antibiotics known as quinolones. It works by inhibiting bacterial DNA gyrase, an enzyme required for replicating, transcribing, and repairing DNA. Satranidazole is an anti-amoebic, antiprotozoal, and antibacterial medicine that treats various infections caused by bacteria and parasites (amoebas). It is bactericidal, killing harmful bacteria and parasites (such as amoebas) by damaging their DNA. It prevents the division of bacterial cells and inhibits the repair of bacterial cells.

Storage

Keep out of sight and reach of children.

What if I have taken an overdose of Satrogyl O Tablet

Do not take more than the prescribed dose of Satrogyl O Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Brief your medical history to the doctor if you are allergic to Satrogyl O Tablet or any of its components. Please let your doctor know in advance if you have liver or kidney diseases, tendonitis, fits, blood dyscrasia, colitis, diabetes, myasthenia gravis (muscle weakness), dehydration, high blood pressure, nerve problems (peripheral neuropathy), mental/mood disorders (depression) or are undergoing dialysis treatment. Please consult your doctor if you are planning to become pregnant or are already pregnant before starting Satrogyl O Tablet . Do not drive or operate heavy machinery after taking Satrogyl O Tablet as it may cause dizziness and visual disturbances. Please try avoiding alcoholic beverages during your treatment, as they can cause flushing and a general sick feeling. Satrogyl O Tablet is not recommended for children less than 18 years of age.

Drug-Drug Interactions

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OfloxacinBepridil
Critical
OfloxacinZiprasidone
Critical

Drug-Drug Interactions

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OfloxacinBepridil
Critical
How does the drug interact with Satrogyl O Tablet:
Using bepridil together with Satrogyl O Tablet drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Satrogyl O Tablet with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
OfloxacinZiprasidone
Critical
How does the drug interact with Satrogyl O Tablet:
Coadministration of Satrogyl O Tablet with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Satrogyl O Tablet with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinCisapride
Critical
How does the drug interact with Satrogyl O Tablet:
Coadministration of Satrogyl O Tablet with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Satrogyl O Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.
OfloxacinPimozide
Critical
How does the drug interact with Satrogyl O Tablet:
Coadministration of Satrogyl O Tablet with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Satrogyl O Tablet with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinDisopyramide
Critical
How does the drug interact with Satrogyl O Tablet:
Coadministration of Satrogyl O Tablet with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Satrogyl O Tablet with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Satrogyl O Tablet:
Coadministration of Satrogyl O Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Satrogyl O Tablet with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinQuinidine
Critical
How does the drug interact with Satrogyl O Tablet:
Coadministration of Satrogyl O Tablet with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Satrogyl O Tablet with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinMesoridazine
Critical
How does the drug interact with Satrogyl O Tablet:
Using Mesoridazine together with Satrogyl O Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Satrogyl O Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinThioridazine
Critical
How does the drug interact with Satrogyl O Tablet:
Coadministration of Satrogyl O Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Satrogyl O Tablet with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinAmiodarone
Critical
How does the drug interact with Satrogyl O Tablet:
The combination of Amiodarone and Satrogyl O Tablet may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and Satrogyl O Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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OFLOXACIN-200MG+SATRANIDAZOLE-300MGCalcium rich foods, Caffeine containing foods/drinks
Moderate

Drug-Food Interactions

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OFLOXACIN-200MG+SATRANIDAZOLE-300MGCalcium rich foods, Caffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt, Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Consumption of caffeine, calcium, iron, magnesium, and aluminum containing food while on the treatment with Ofloxacin can lead to decrease in blood levels of Ofloxacin. Avoid or limit consumption of caffeine, calcium, iron, magnesium, and aluminum containing food while on the treatment with Ofloxacin.

Diet & Lifestyle Advise

  • Antibiotics can alter the beneficial bacteria in the stomach. Therefore, you are advised to consume foods rich in probiotics, such as yoghurt, curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas, and bananas.
  • Avoid foods rich in calcium, such as grapefruit and grapefruit juice, as they may hinder the absorption of antibiotics.
  • If you have diarrhoea, try to drink appropriate amounts of fluids to avoid dehydration.
  • If you have minor diarrhoea (less than four stools daily), drinking caffeine-free soft drinks, juices, or sport rehydration drinks can be sufficient.
  • If the diarrhoea is more severe, specially formulated rehydration drinks should be taken.
  • Avoid alcoholic beverages with Satrogyl O Tablet as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Satrogyl O Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Satrogyl O Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Alcohol consumption may worsen the side effects of Satrogyl O Tablet , like dizziness and visual disturbances. It is better to avoid alcohol while you are being treated with Satrogyl O Tablet .

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Pregnancy

Caution

There is limited data on how the Satrogyl O Tablet affects pregnancy. Please consult your doctor if you are planning to become pregnant or are already pregnant before starting Satrogyl O Tablet .

bannner image

Breast Feeding

Caution

Satrogyl O Tablet is excreted into the breast milk and may affect the nursing infants. Please consult your doctor before taking Satrogyl O Tablet if you are breastfeeding.

bannner image

Driving

Caution

Do not drive or operate machinery if you experience any impairment of skills, dizziness and visual disturbances while using Satrogyl O Tablet .

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Liver

Caution

Please take Satrogyl O Tablet with caution and doctor’s advice if you have a history of liver diseases/conditions.

bannner image

Kidney

Caution

Please take Satrogyl O Tablet with caution and doctor’s advice if you have a history of kidney diseases/conditions.

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Children

Unsafe

Satrogyl O Tablet is not recommended for children less than 18 years of age.

Have a query?

FAQs

Satrogyl O Tablet is used to treat diarrhoea and dysentery. It helps treat bacterial infections, including intra-abdominal infection, gynaecological and pelvic infections, foot ulcers in diabetes, post-operative infections, dental infections, and infections in immunocompromised patients.

Satrogyl O Tablet contains Ofloxacin and Satranidazole. These drugs are antibiotics that kill and prevent the bacterial growth that causes diarrhoea, dysentery, and other bacterial infections.

Please let your doctor know if you have a history of allergic reactions to medicines, liver or kidney diseases, high blood pressure, nerve problems (peripheral neuropathy), mental/mood disorders (depression), tendonitis (inflammation of the tendon, a tissue connecting muscle and bone), fits, blood dyscrasia (decreased peripheral blood cell counts), colitis (inflammation of the colon), diabetes, myasthenia gravis (muscle weakness), dehydration and undergoing dialysis treatment.

Satrogyl O Tablet consists of Ofloxacin, a quinolone antibiotic that may cause hypoglycaemia (low blood sugar levels) or hyperglycaemia (high blood sugar levels). It is advised to consult your doctor before using Satrogyl O Tablet and monitor your blood sugar levels regularly.

Do not stop using Satrogyl O Tablet even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the infection may not be cured completely.

For most healthy individuals, taking ibuprofen with Satrogyl O Tablet is generally safe. However, those with a history of seizures, epilepsy, other nervous system disorders, or kidney problems, as well as those taking medicines that affect the brain, should use this combination with caution and under medical supervision.

Satrogyl O Tablet contains a quinolone antibiotic, Ofloxacin, which can affect live vaccines, such as the typhoid vaccine, and decrease its effectiveness. Please consult a doctor before you start Satrogyl O Tablet if you are undergoing any vaccinations.

It is recommended to maintain a minimum gap of two hours between magnesium/aluminium antacids, sucralfate, zinc or iron preparations and Satrogyl O Tablet .

Satrogyl O Tablet may cause side effects like nausea, vomiting, stomach pain, loss of appetite, dizziness, and headache. Most of these side effects of Satrogyl O Tablet do not require medical attention and typically resolve on their own over time. If these side effects persist longer, please consult your doctor.

Do not exceed the recommended dose as it may cause unpleasant side effects. Consult the doctor if you have taken an overdose of Satrogyl O Tablet .

Consult the doctor if you have no improvement even after taking Satrogyl O Tablet for the prescribed duration. The doctor might adjust the dose or prescribe alternative medicine based on your condition.

Consult your doctor before taking other medications with Satrogyl O Tablet to prevent any potential interactions. Please inform the doctor if you are taking blood thinners, pain medications, or herbal supplements.

Before starting Satrogyl O Tablet , inform the doctor if you are allergic to any of the components in Satrogyl O Tablet , have epilepsy, tendonitis (tendon inflammation), glucose-6-dehydrogenase deficiency, are pregnant or breastfeeding, have a history of mental illness, or have liver/kidney/heart problems.

If you miss a dose of Satrogyl O Tablet , take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Alcohol consumption may worsen the side effects of Satrogyl O Tablet , like dizziness and visual disturbances. It is better to avoid alcohol while you are being treated with Satrogyl O Tablet .

Satrogyl O Tablet is not recommended during pregnancy. Consult the doctor if you are pregnant, think you are pregnant or are planning to become pregnant.

Satrogyl O Tablet may cause dizziness, sleepiness and visual disturbances. Therefore, avoid driving or operating machinery unless you are alert.

Store Satrogyl O Tablet at room temperature in a dry place. Keep it out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - SAT0001

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:43 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.alkemlabs.com/pdf/adverse/SATROGYL-O%20TABLETS%20&amp;%20SYRUP.pdf
  2. https://www.unitedpharmacies.md/Satrogyl-Satranidazole.html
  3. https://www.medicines.org.uk/emc/files/pil.8480.pdf
  4. https://www.drugs.com/dosage/ofloxacin.html
  5. https://www.webmd.com/drugs/2/drug-7792/ofloxacin-oral/details

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