It is not recommended to self-medicate with the combination of satranidazole and ofloxacin, or with loperamide, without a doctor's evaluation. Satranidazole and ofloxacin are powerful antimicrobials meant only for specific bacterial or parasitic infections, while loperamide stops bowel movements. Using drugs like loperamide can sometimes trap harmful pathogens in your gut, potentially worsening your condition. For watery diarrhea, the most crucial step is preventing dehydration. Please drink Oral Rehydration Salts (ORS) and plenty of fluids to stay hydrated, and consult a doctor to get a proper diagnosis and a safe, tailored treatment plan.