apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:SULFASALAZINE-500MG
prescription
Prescription Medicine
info
image icons
image icons
image icons
image icons
image icons
Best Price

₹56 with coupons & bank offers*

View

Sazo 500 Tablet is used to treat bowel diseases (ulcerative colitis, Crohn's disease), skin-related problems (psoriasis), and chronic joint diseases (rheumatoid arthritis, ankylosing spondylitis) in children and adults. It contains Sulfasalazine, which works as an inflammation reducer by acting locally, inhibiting the formation of a chemical known as prostaglandins, that control pain and inflammation. Thus, it helps reduce the inflammation of the intestine, skin, and joints. In some cases, you may experience a sore throat, a fever, unexplained bruising, or ringing in your ears (tinnitus). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Read more
Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
Get Extra 18% Off with Coupons
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

SULFASALAZINE-500MG

Manufacturer/Marketer :

Wallace Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Sazo 500 Tablet

Sazo 500 Tablet is a prescription medicine used to reduce inflammation and help manage certain chronic inflammatory conditions. It is commonly prescribed for inflammatory bowel diseases such as ulcerative colitis and for inflammatory joint conditions such as rheumatoid arthritis. By helping control inflammation, this medicine can reduce symptoms and support long-term disease management.

Take Sazo 500 Tablet exactly as prescribed by your doctor. It is usually taken with food and a full glass of water to help reduce stomach discomfort. Taking the medicine regularly, even when you feel well, helps maintain symptom control and reduce the risk of disease flare-ups.

Some people may experience mild side effects such as nausea, headache, loss of appetite, or stomach discomfort when starting treatment. These effects are often temporary and may improve as your body adjusts to the medicine. However, contact your doctor promptly if you develop severe skin reactions, unusual bruising or bleeding, yellowing of the skin or eyes, persistent fever, or signs of an allergic reaction.

Before taking Sazo 500 Tablet , inform your doctor if you have kidney disease, liver disease, asthma, blood disorders, or a history of allergies to sulfonamides or aspirin-containing medicines. This medicine may not be suitable for people with certain intestinal or urinary tract blockages.

Limit alcohol consumption while taking this medicine, as excessive alcohol use may increase the risk of liver-related side effects. Tell your doctor if you are pregnant, planning to become pregnant, breastfeeding, or trying to conceive so they can determine whether this medicine is appropriate for you. 

Uses of Sazo 500 Tablet

Sazo 500 Tablet is used to treat inflammatory bowel diseases and inflammatory joint conditions. The detailed uses of Sazo 500 Tablet are as follows:

  • Ulcerative Colitis: Helps reduce inflammation in the lining of the large intestine and supports both symptom control and maintenance of remission.
  • Rheumatoid Arthritis: Helps reduce joint pain, swelling, stiffness, and inflammation in people with rheumatoid arthritis.
  • Crohn's Disease: May be used in selected patients with mild-to-moderate inflammatory bowel disease, particularly when inflammation affects the colon.
  • Other Inflammatory Conditions: In certain situations, doctors may prescribe this medicine for other inflammatory disorders based on individual patient needs.

Key Benefits

Sazo 500 Tablet helps control chronic inflammation and supports long-term management of inflammatory conditions. Regular treatment may improve comfort, mobility, and overall quality of life.

  • Improved Joint Comfort: Helps reduce pain, stiffness, and swelling associated with inflammatory arthritis.
  • Better Physical Function: Supports improved movement and daily activities by helping control inflammation.
  • Supports Digestive Health: Helps reduce symptoms such as abdominal discomfort, diarrhoea, and rectal bleeding associated with ulcerative colitis.
  • Helps Prevent Disease Flare-Ups: Consistent use may reduce the frequency and severity of symptom recurrence in chronic inflammatory conditions.
Side effects of Sazo 500 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Boost your immunity by including immune-rich foods in your diet, and always remember to stay hydrated.
  • Get sufficient sleep and manage stress, which helps improve white blood cell count.
  • Consult your doctor for an effective treatment to improve immunity and get regular body check-ups to monitor changes in the count.
  • Exercise regularly to lower stress and improve stamina and immunity.
  • Smoking can affect immunity. It is advisable to avoid such a habit.
  • Practice good hygiene practices to lower the chances of falling sick.

Directions for Use

To get the full benefit of Sazo 500 Tablet and minimise side effects, follow these simple guidelines:

  • Take the tablet orally with food and a full glass of water.
  • Swallow the tablet whole. Do not crush, chew, or break it unless specifically instructed by your doctor.
  • Drink plenty of fluids throughout the day to help support healthy kidney function.
  • Take the medicine at the same time each day to maintain consistent levels in your body.
  • Continue taking the medicine regularly unless your doctor advises otherwise.
  • Always follow your doctor's exact instructions regarding dosage and duration of treatment.
     

How Sazo 500 Tablet Works

Sazo 500 Tablet contains sulfasalazine. After it reaches the intestine, natural bacteria break the medicine into active components that help reduce inflammation. Reduces Inflammation in the Bowel: One component acts directly within the intestine to help decrease inflammation and tissue irritation. Modulates Immune Activity: The medicine helps regulate inflammatory processes that contribute to joint swelling and stiffness in rheumatoid arthritis. Supports Long-Term Disease Control: By reducing inflammation in affected tissues, the medicine helps improve symptoms and may slow disease progression in certain conditions. Through these actions, Sazo 500 Tablet helps manage symptoms and support long-term control of inflammatory diseases.
bannner image

Alcohol

Unsafe

It is not recommended to consume alcohol while taking Sazo 500 Tablet to avoid unpleasant side-effects.

bannner image

Pregnancy

Consult your doctor

Sazo 500 Tablet should be recommended in pregnancy only if required. In case, if prescribed to a pregnant woman, it is advised to increase the folate supplementation after consulting your doctor.

bannner image

Breast Feeding

Unsafe

Sazo 500 Tablet is excreted in breastmilk and is not recommended especially if the baby is premature or is at the risk of jaundice. It might cause kernicterus (excessive levels of bilirubin in the blood) in the new-born.

bannner image

Driving

Safe if prescribed

Sazo 500 Tablet does not affect the ability to drive. However, if you feel drowsy after taking Sazo 500 Tablet , it is advised not to drive.

bannner image

Liver

Unsafe

Sazo 500 Tablet is not recommended to use in patients with a history of liver diseases. In other people, rarely, it can cause hepatitis (inflammation of the liver).

bannner image

Kidney

Unsafe

Sazo 500 Tablet is not recommended to use in patients with a history of kidney diseases. In other people, rarely it can cause inflammation of the kidneys.

bannner image

Children

Consult your doctor

Sazo 500 Tablet should be advised in children only if prescribed by a child specialist.

bannner image

Heart

Consult your doctor

Please consult your doctor before using Sazo 500 Tablet if you have pre-existing heart problems. Your doctor will prescribe Sazo 500 Tablet if the benefits outweigh the risks.

bannner image

Geriatrics

Caution

Sazo 500 Tablet should be used under caution in geriatric patients as it can lead to serious side effects.

What if I have taken an overdose of Sazo 500 Tablet

Do not take more than the prescribed dose of Sazo 500 Tablet as it may cause an overdose. The symptoms of overdose include stomach pain, seizures (fits), tiredness, nausea and vomiting. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay Well Hydrated: Drink plenty of water throughout the day to help reduce the risk of kidney-related complications.
  • Follow an Appropriate Diet: If you have inflammatory bowel disease, follow your healthcare provider's dietary recommendations, particularly during flare-ups.
  • Protect Your Skin from Sunlight: This medicine may increase sensitivity to sunlight. Use sunscreen and wear protective clothing when spending time outdoors.
  • Stay Physically Active: Gentle exercise such as walking, swimming, or cycling may help maintain joint flexibility and mobility.
  • Be Aware of Colour Changes: The medicine may cause harmless yellow-orange discoloration of urine, sweat, or tears.
     

Health Queries

What should I do if my severe joint pain is not getting better despite taking Sazo 500mg and HCQS for my inflammatory bowel disease and positive autoimmune blood test, and is it safe to drink alcohol to help relieve the pain while on these medications?

Vikas Singh

Vikas Singh

M Pharmacy

Since Sazo (sulfasalazine) and HCQS (hydroxychloroquine) are not providing relief, please contact your specialist; they may need to adjust your treatment plan. Regarding alcohol, it is highly recommended to avoid it. Mixing alcohol with these medications can significantly increase the risk of liver strain and irritate your digestive tract, which can worsen your inflammatory bowel disease. Alcohol is not safe for pain relief here. Please consult your doctor soon so they can safely help you find comfort.

Is it safe for my mother to get the Covishield vaccine if she is being treated for weak bones (osteoporosis), recently stopped taking the medication Sazo, and has high inflammation (CRP) and liver enzyme (SGPT) levels?

Veda Maddala

Veda Maddala

M Pharmacy

While osteoporosis treatments are generally safe with the Covishield vaccine, her elevated liver enzymes (SGPT) and high inflammation (CRP) require careful attention. Since she recently stopped Sazo (sulfasalazine), her body may be experiencing active inflammation. It is usually best to wait until her liver enzymes and inflammation levels stabilize before she gets vaccinated. This ensures her body is in the best position to handle the vaccine safely. Please consult her physician to evaluate her liver function and determine the safest time for her vaccination.

Could my spine arthritis medications?Sazo 1000mg, Retoz, and Folvites?be worsening my skin fungal infection, and is it safe to take skin fungus treatments at the same time as these medicines?

Veda Maddala

Veda Maddala

M Pharmacy

Sazo (sulfasalazine) gently calms your immune system to help your arthritis, which can occasionally make it slightly harder for your body to clear a fungal infection. Retoz (etoricoxib) and Folvites (folic acid) do not worsen fungal issues. Regarding treatments, using topical antifungal creams is generally very safe and won't interfere with your medicines. However, if you require oral antifungal tablets, they can sometimes interact with Sazo or Retoz. Please share your symptoms with your doctor so they can prescribe the safest, most effective treatment for you.

What are the long-term health risks and potential side effects associated with a combined medication regimen of weekly methotrexate (Mext 15) and daily sulfasalazine (Sazo 500), hydroxychloroquine (HCQS 200), and deflazacort (Defgold)?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

This combination is highly effective for controlling inflammation. Long-term, methotrexate and sulfasalazine require routine blood tests to monitor your liver and blood counts. Hydroxychloroquine requires periodic eye exams to protect your vision. Deflazacort, a steroid, is wonderful for quick relief, but long-term use can affect bone density and blood sugar, so we always aim to taper it safely. Regular monitoring makes this regimen very manageable.

Could my 57-year-old mother's long-term use of her arthritis medications?Sazo, Folvite, Gemcal, Mayospaz, and Pan-D?be causing her recently rising liver enzyme (SGPT) and blood inflammation markers (ESR and CRP), and do these increasing test results indicate a serious health problem?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Some of your mother's medications, particularly Sazo (sulfasalazine), can occasionally cause elevated liver enzymes (SGPT). Additionally, the increase in her inflammation markers (ESR and CRP) likely reflects her underlying arthritis being active rather than a sudden, serious danger. These results are helpful clues for her doctor, not a reason to panic. I highly recommend sharing these reports with her rheumatologist. They can easily review and adjust her medications to safely bring both her liver enzymes and arthritis inflammation back to comfortable levels.
health query

Have a query?

How Soon It Starts Working

The time required for Sazo 500 Tablet to start to work: The time required for Sazo 500 Tablet to show its action is not clinically established. The time for which the effects of Sazo 500 Tablet last: The duration of action for Sazo 500 Tablet is not clinically established.

What if you forget to take Sazo 500 Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store Sazo 500 Tablet at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from moisture and light.

Drug Warnings

  • Attend Regular Blood Tests: Your doctor may monitor your blood counts, liver function, and kidney function during treatment.
  • Monitor for Signs of Infection: Report persistent fever, chills, sore throat, or other symptoms of infection to your healthcare provider.
  • Check for Skin Reactions: Seek medical advice if you develop a rash, blistering, or unusual skin changes.
  • Inform Healthcare Providers: Tell your doctor, dentist, or surgeon that you are taking this medicine before any procedure.
  • Be Aware of Contact Lens Staining: Soft contact lenses may become permanently discoloured due to changes in tear colour.
     

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions
Inform your doctor if you are taking any of the following medicines, as they may interact with Sazo 500 Tablet :

  • Digoxin: Sulfasalazine may reduce the absorption of digoxin, potentially decreasing its effectiveness.
  • Blood Thinners: Medicines such as warfarin may increase the risk of bleeding when used together.
  • Oral Diabetes Medicines: May increase the risk of low blood sugar in some patients.
  • Methotrexate: Concurrent use may increase the risk of certain side effects and may require closer monitoring.
  • Folic Acid Supplements: Sulfasalazine may reduce folic acid absorption, and supplementation may be recommended.

Drug-Food Interactions

  • Iron Supplements: Iron may reduce the absorption of sulfasalazine. Your doctor may recommend separating the timing of these medicines.
  • Alcohol: Excessive alcohol consumption may increase the risk of liver-related side effects.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Sazo 500 Tablet , as it may worsen your condition or require additional monitoring:

  • Kidney Disease: May increase the risk of kidney-related complications.
  • Liver Disease: May increase the risk of liver toxicity.
  • Asthma: Some people with asthma may be more likely to experience allergic or sensitivity reactions.
  • Blood Disorders: Sulfasalazine may affect blood cell production and require closer monitoring.
     
SulfasalazineCidofovir
Critical
SulfasalazineProcaine
Severe

Drug-Drug Interactions

Login/Sign Up

SulfasalazineCidofovir
Critical
How does the drug interact with Sazo 500 Tablet:
Coadministration of Cidofovir with Sazo 500 Tablet can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Sazo 500 Tablet with Cidofovir is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
SulfasalazineProcaine
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Sazo 500 Tablet with Procaine can increase the risk of methemoglobinemia, (a rare red blood cell condition where the oxygen-carrying capacity decreases).

How to manage the interaction:
Although taking Procaine and Sazo 500 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineWarfarin
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of warfarin with Sazo 500 Tablet can increase the risk of unusual bleeding disorder.

How to manage the interaction:
Although taking Sazo 500 Tablet and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache; and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
SulfasalazineRopivacaine
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Sazo 500 Tablet with Ropivacaine can increase the risk of methemoglobinemia, (a rare red blood cell condition where the oxygen-carrying capacity decreases).

How to manage the interaction:
Although taking Ropivacaine and Sazo 500 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineDeferasirox
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Deferasirox and Sazo 500 Tablet may increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Sazo 500 Tablet and Deferasirox together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
SulfasalazineTeriflunomide
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of teriflunomide with Sazo 500 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Teriflunomide and Sazo 500 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as paleness, fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineDicoumarol
Severe
How does the drug interact with Sazo 500 Tablet:
Using Dicoumarol together with Sazo 500 Tablet may increase the risk or severity of bleeding. The risk increases in patients with a history of liver or kidney disorders.

How to manage the interaction:
There may be a possibility of interaction between Sazo 500 Tablet and Dicoumarol, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness call a doctor. Do not discontinue any medications without consulting a doctor.
SulfasalazinePrilocaine
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Sazo 500 Tablet with Prilocaine can increase the risk of methemoglobinemia, (a rare red blood cell disorder in which oxygen carrying effectively reduces).

How to manage the interaction:
Although taking Prilocaine and Sazo 500 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
SulfasalazineTenofovir disoproxil
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Sazo 500 Tablet and Tenofovir disoproxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Sazo 500 Tablet and Tenofovir disoproxil together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SulfasalazineCiclosporin
Severe
How does the drug interact with Sazo 500 Tablet:
Coadministration of Sazo 500 Tablet with ciclosporin may significantly increase the side effects on kidneys.

How to manage the interaction:
Although there is a possible interaction between Sazo 500 Tablet and ciclosporin, they can be taken together if your doctor has prescribed them. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without first talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Customers Also Bought

Apollo Pharmacy Vitamin C Effervescent, 20 Tablets

Apollo Pharmacy Vitamin C Effervescent, 20 Tablets

₹144.7

₹195.526% off

Habit Forming

No

Therapeutic Class

[GASTROINTESTINAL AGENTS]

FAQs

Sazo 500 Tablet is used to treat bowel diseases (ulcerative colitis, Crohn's disease), skin-related problems (psoriasis), and chronic joint diseases (rheumatoid arthritis, ankylosing spondylitis).
Yes, Sazo 500 Tablet is contraindicated in patients with intestinal or urinary obstruction, patients with porphyria (liver disorders), and patients hypersensitive to sulfasalazine, its metabolites, sulfonamides, or salicylates.
In some men, sulfasalazine may temporarily reduce sperm count. This effect is generally reversible after treatment is stopped. Talk to your doctor or pharmacist if you are planning a family.
Yes, Sazo 500 Tablet is safe to use in breastfeeding. However, please inform your doctor if the baby is premature or is at risk of jaundice as this medicine might not be advised in such cases.
Yes, Sazo 500 Tablet can rarely affect blood cells and may cause conditions such as leukopenia (low white blood cell count) or, in rare cases, agranulocytosis. Because of this risk, your doctor may recommend regular monitoring with blood counts and other laboratory tests, including kidney and liver function tests. Monitoring is usually more frequent during the first year of treatment. Contact your doctor if you develop symptoms such as fever, sore throat, rash, or signs of infection.
No, Sazo 500 Tablet is a disease-modifying anti-rheumatic drug’ (DMARD) and not a painkiller. So, if you are taking a painkiller before starting this medicine, you can continue taking it along with Sazo 500 Tablet .
No, Sazo 500 Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side-effects. If you think your symptoms are not improving, please consult your doctor.
Sazo 500 Tablet may cause central nervous system adverse effects such as serious psychiatric problems including mania, depression, and psychosis, and these symptoms have been reported to occur only infrequently.
The side effects of Sazo 500 Tablet include headache, nausea, indigestion and watery diaarhoea. If these side effects persist or worsen, please consult your doctor.
Improvement may take several weeks after starting Sazo 500 Tablet . Some patients notice symptom relief within 4–6 weeks, while the full benefits may take 8–12 weeks or longer, especially in rheumatoid arthritis. Continue taking the medicine as prescribed and do not stop treatment without consulting your doctor.
You are recommended to avoid using azathioprine along with Sazo 500 Tablet as it may decrease blood cell count, which can be a serious side effect. However, please consult your doctor before taking other medicines with Sazo 500 Tablet to avoid drug interactions.
Yes. Sazo 500 Tablet may cause harmless yellow-orange discoloration of urine, sweat, saliva, or tears. Because of this, soft contact lenses may become permanently stained and should be used with caution. However, yellowing of the skin or eyes should be reported to your doctor immediately, as it may indicate a liver problem.
No. The tablets should generally be swallowed whole with water unless your doctor specifically advises otherwise. Crushing or chewing them may affect how the medicine works. Talk to your doctor or pharmacist if you have difficulty swallowing tablets.
Your doctor will determine whether this medicine is appropriate during pregnancy based on your individual circumstances. Folic acid supplementation may be recommended. Talk to your doctor or pharmacist if you are pregnant or planning to become pregnant.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 007073S124Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Sulphaslazine2 - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Sulfasalazine Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Sulfasalazine [EMC Label]. 2010. [Accessed on 23 Jan. 2019]Check here
  5. Sulfasalazine [Patient Information Leaflet]. 2018. [Accessed on 18 Jun. 2019]Check here
  6. Sulfasalazine [Prescribing Information]. 2014. [Accessed on 18 Jun. 2019]Check here
  7. Choi J, Fenando A Sulfasalazine. [Updated 2022 Nov 11]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023Check here

Country of origin

INDIA

Manufacturer/Marketer address

Wallace Pharmaceuticals Pvt. Ltd., 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.
Other Info - SAZ0004
whatsapp Floating Button
Buy Now
Add 6 Strips