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  3. Sefepime Injection

Sefepime Injection, Pack of 1 Injection
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Sefepime Injection is used to treat bacterial infections. It works by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as diarrhoea, rashes, anaemia, pain and inflammation at the site of injection. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

CEFEPIME-1GM

Manufacturer/Marketer :

Scott Edil Pharmacia Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Sefepime Injection

Sefepime Injection belongs to the group of antibiotic medicines called cephalosporins used to treat respiratory tract infection, urinary tract infection, skin, intraabdominal, gynaecological, bacterial meningitis (infection of brain and spinal cord) in children, and infection of the bloodstream. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body.
 
Sefepime Injection works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections. Sefepime Injection is a broad-spectrum antibiotic active against both gram-positive and gram-negative bacteria.
 
In some cases, Sefepime Injection may cause common side-effects such as diarrhoea, rashes, anaemia, pain and inflammation at the site of injection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Sefepime Injection may cause dizziness, so drive with caution. Sefepime Injection is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Sefepime Injection

Treatment of Bacterial infections

Directions for Use

Sefepime Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Sefepime Injection belongs to the group of antibiotic medicines called cephalosporin antibiotics. Sefepime Injection is used to treat respiratory tract infection, urinary tract infection, skin, intraabdominal, gynaecological, bacterial meningitis (infection of the brain and spinal cord) in children, and infection of the bloodstream. Sefepime Injection is a broad-spectrum antibiotic active against both gram-positive and gram-negative bacteria. Sefepime Injection prevents the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections. 

How Sefepime Injection Works

Sefepime Injection works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections. Sefepime Injection is a broad-spectrum antibiotic active against both gram-positive and gram-negative bacteria.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sefepime Injection
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.

What if I have taken an overdose of Sefepime Injection

It is unlikely to overdose on parenteral medication as it is administered by a healthcare professional. However, seek medical attention if you experience symptoms of overdose such as seizures, myoclonus (involuntary twitching), neuromuscular excitability, and encephalopathy (disturbance of consciousness including confusion, hallucinations, stupor, and coma).

Drug Warnings

Do not take Sefepime Injection if you are allergic to any of the components. Talk to your doctor if you have/had intestinal problems, malnourishment, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Sefepime Injection may cause dizziness, so be cautious while driving. Consult a doctor if you notice any unusual bleeding or bruising.

Drug-Drug Interactions

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CefepimeCholera vaccines
Severe
CefepimeCholera, live attenuated
Severe

Drug-Drug Interactions

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CefepimeCholera vaccines
Severe
How does the drug interact with Sefepime Injection:
Taking the cholera vaccine after or along with Sefepime Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Sefepime Injection and Cholera vaccines together can evidently cause an interaction, it can be taken if your doctor has suggested it. Make sure to inform the doctor if you are on Cholera vaccine dose or you have already taken it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
CefepimeCholera, live attenuated
Severe
How does the drug interact with Sefepime Injection:
Taking the cholera vaccine after or along with Sefepime Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Sefepime Injection and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. Make sure to inform the doctor if you are on Cholera vaccine dose or you have already taken it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Sefepime Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known if alcohol interacts with Sefepime Injection. Please consult a doctor.

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Pregnancy

Caution

Sefepime Injection belongs to pregnancy category B. Please consult your doctor if you are pregnant; your doctor will prescribe Sefepime Injection only if the benefits outweigh the risks.

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Breast Feeding

Caution

Sefepime Injection may pass into breastmilk. Sefepime Injection should be used with great care in breastfeeding women if prescribed by the doctor.

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Driving

Caution

Sefepime Injection may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Safe if prescribed

Sefepime Injection is safe for children above 2 months if prescribed by a doctor. The dose and duration may vary depending on the child’s weight. The safety and effectiveness of Sefepime Injection in children below 2 months have not been established.

Have a query?

FAQs

Sefepime Injection works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections.

Diarrhoea might be a side-effect of Sefepime Injection. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Sefepime Injection may cause thrush or candidiasis, a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent fungal infections.

It is recommended to complete the course of Sefepime Injection even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).

Sefepime Injection may cause increased coagulation time (increased thromboplastin/ prothrombin time) which is the time required for the blood to clot. Therefore, be cautious while using any sharp objects and consult a doctor immediately if you notice any unusual bleeding or bruising.

Sefepime Injection might increase the effect of coumarin (anticoagulant medicine), therefore, consult a doctor before taking them together.

Sefepime Injection belongs to the group of antibiotic medicines called cephalosporins used to treat respiratory tract infection, urinary tract infection, skin, intraabdominal, gynaecological, bacterial meningitis (infection of brain and spinal cord) in children, and infection of the bloodstream.

No, Sefepime Injection should not be self-administered. It is typically given by a healthcare professional, such as a doctor or nurse, either by intravenous (IV) or intramuscular (IM) injection.

Sefepime Injection typically starts working soon after administration. However, it may take a few days to notice significant improvement in symptoms.

Inform your doctor if you don't feel better after finishing the full course of treatment as prescribed by your doctor. Also, inform your doctor if your symptoms are getting worse while using Sefepime Injection. They might prescribe a different medication or adjust your treatment plan based on your symptoms and medical history.

The common side effects of Sefepime Injection are diarrhoea, rashes, anaemia, pain and inflammation at the site of injection. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - SE32300

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:47 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.9672.pdf
  2. https://www.drugs.com/cdi/cefepime.html
  3. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=be5f8ca6-7232-423a-a2d5-cccb7abe7921
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