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compositionComposition:DICLOFENAC-50MG+SERRATIOPEPTIDASE-10MG
prescriptionPrescription Medicine
Seram DP 50mg/10mg Tablet

Seram DP 50mg/10mg Tablet is used in the reduction of pain and inflammation related to conditions such as bone or soft tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea). It helps relieve pain and swelling in the affected tissues by blocking certain chemicals that cause pain and breaking down insoluble proteins (fibrin) in blood clots. It also supports faster healing by promoting the drainage of excess fluid from swollen tissues.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DICLOFENAC-50MG+SERRATIOPEPTIDASE-10MG

Manufacturer/Marketer :

Ambit Bio Medix

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

Seram DP 50mg/10mg Tablet is used in the treatment of pain and inflammation associated with various conditions, such as bone or soft tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea).

Seram DP 50mg/10mg Tablet contains Diclofenac and Serratiopeptidase. Diclofenac blocks the action of a chemical messenger (cyclo-oxygenase) that causes pain and swelling at the injured or damaged tissue. Serratiopeptidase helps degrade insoluble protein (fibrin) in blood clots and thin fluids in the affected area, thereby reducing swelling.

Take Seram DP 50mg/10mg Tablet exactly as prescribed by your doctor. Swallow it whole with a glass of water; do not crush, chew, or break it. Seram DP 50mg/10mg Tablet may cause common side effects such as stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Please consult your doctor if the side effects persist or worsen.

Do not take Seram DP 50mg/10mg Tablet if you are allergic to any of its ingredients or to other painkillers such as aspirin, ibuprofen, naproxen, or diclofenac. Avoid taking Seram DP 50mg/10mg Tablet during the last trimester of pregnancy unless advised by your doctor. It is not recommended for use in children. Do not take Seram DP 50mg/10mg Tablet if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure).

Uses of Seram DP 50mg/10mg Tablet

Seram DP 50mg/10mg Tablet is used in the treatment of pain. The detailed uses of Seram DP 50mg/10mg Tablet are as follows:

  • Reduction of pain and inflammation: Seram DP 50mg/10mg Tablet helps relieve pain and swelling associated with various conditions, including bone or soft-tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea).

Key Benefits

Seram DP 50mg/10mg Tablet offers the following medicinal benefits:

  • Effectively reduces musculoskeletal pain from conditions such as back pain, arthritis, spondylitis, and muscle injuries.
  • Relieves pain and swelling after surgeries, sprains, fractures, and other soft-tissue injuries.
  • Helps manage pain associated with toothaches, dental procedures, sore throat, and ear infections.
  • Supports healing by promoting fluid drainage from swollen tissues, helping inflammation decrease more quickly.
Side effects of Seram DP 50mg/10mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Seram DP 50mg/10mg Tablet can be taken with or without food. However, taking it with food may help reduce stomach upset.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Seram DP 50mg/10mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.
Seram DP 50mg/10mg Tablet contains two medications: Diclofenac and Serratiopeptidase. • Diclofenac: It is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the action of a chemical messenger (cyclo-oxygenase) responsible for causing pain and swelling at the injured or damaged tissue. • Serratiopeptidase: It is a proteolytic enzyme that helps break down insoluble protein (fibrin) in blood clots and thins fluids in the affected area, making it easier for excess fluid to drain and helping to reduce swelling. • Together, these medications help relieve pain and inflammation.
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Alcohol

Caution

You are recommended not to consume alcohol along with Seram DP 50mg/10mg Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning to become pregnant before taking Seram DP 50mg/10mg Tablet.

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Breast Feeding

Caution

Seram DP 50mg/10mg Tablet may enter breast milk. Consult your doctor for more information on this if you are a breastfeeding mother.

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Driving

Caution

Seram DP 50mg/10mg Tablet may impair driving, as it can cause dizziness. Drive or operate machinery only when you are alert.

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Liver

Caution

Seram DP 50mg/10mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Seram DP 50mg/10mg Tablet to be taken with caution if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Seram DP 50mg/10mg Tablet is not recommended for children under 10 years of age. For them, the dose must be adjusted and recommended only by a child specialist.

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Heart

Unsafe

Seram DP 50mg/10mg Tablet should be avoided in cardiac patients, as it can lead to serious cardiovascular risks

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Geriatrics

Caution

Seram DP 50mg/10mg Tablet should be used with caution in geriatric patients, as it can cause serious side effects.

Do not take more than the prescribed dose of Seram DP 50mg/10mg Tablet, as it may cause serious side effects or poisoning. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

Dietary supplements:

  • Include supplements rich in glucosamine, chondroitin sulphate, vitamin D, and calcium.
  • Turmeric and fish oils can help reduce inflammation in the tissues.

Anti-inflammatory foods:

  • Include fatty fish like salmon, trout, tuna, and sardines in your diet. These are rich in omega-3 fatty acids that help reduce inflammation.

Physical activity:

  • Avoid heavy exercise, as it may exacerbate joint pain in arthritis.
  • Focus on stretching and low-impact aerobic exercise, such as walking on a treadmill, cycling, or swimming.
  • Strengthen muscles with light weightlifting to support joint health.

Posture and sitting habits:

  • Avoid prolonged sitting; keep sitting periods short (10-15 minutes).
  • Use back support, such as a rolled-up towel, to maintain the natural curve of your spine.
  • Keep your knees and hips at right angles while sitting.
  • Use a footrest if needed to reduce strain.

Have a query?

Drug Warnings

  • Do not take Seram DP 50mg/10mg Tablet if you are allergic to any of its ingredients or to other painkillers such as aspirin, ibuprofen, naproxen, or diclofenac.
  • Avoid taking Seram DP 50mg/10mg Tablet during the last trimester of pregnancy unless advised by your doctor.
  • Seram DP 50mg/10mg Tablet is not recommended for use in children.
  • Do not take Seram DP 50mg/10mg Tablet if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure).
  • Do not drive or operate heavy machinery after intake of Seram DP 50mg/10mg Tablet, as it may cause dizziness.
  • Patients who have recently undergone heart bypass surgery should take Seram DP 50mg/10mg Tablet with caution and only under medical supervision.
  • Use of Seram DP 50mg/10mg Tablet is contraindicated in patients with kidney failure or those undergoing dialysis.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacTacrolimus
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Seram DP 50mg/10mg Tablet:
Co-administration of Seram DP 50mg/10mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Seram DP 50mg/10mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacTacrolimus
Severe
How does the drug interact with Seram DP 50mg/10mg Tablet:
Co-administration of Seram DP 50mg/10mg Tablet with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Seram DP 50mg/10mg Tablet and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
DiclofenacIbrutinib
Severe
How does the drug interact with Seram DP 50mg/10mg Tablet:
Taking Seram DP 50mg/10mg Tablet with Ibrutinib can increase the risk of bleeding tendencies.

How to manage the interaction:
There may be a possible interaction between Seram DP 50mg/10mg Tablet and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.
DiclofenacTolmetin
Severe
How does the drug interact with Seram DP 50mg/10mg Tablet:
Taking Seram DP 50mg/10mg Tablet with Tolmetin may increase the risk of side effects.

How to manage the interaction:
There may be a possible interaction between Seram DP 50mg/10mg Tablet and Tolmetin but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacApixaban
Severe
How does the drug interact with Seram DP 50mg/10mg Tablet:
Co-administration of Seram DP 50mg/10mg Tablet and Apixaban may raise the risk of stomach bleeding.

How to manage the interaction:
Although there is a interaction between Seram DP 50mg/10mg Tablet and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacDasatinib
Severe
How does the drug interact with Seram DP 50mg/10mg Tablet:
Taking Dasatinib together with Seram DP 50mg/10mg Tablet may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Seram DP 50mg/10mg Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Seram DP 50mg/10mg Tablet:
Co-administration of Seram DP 50mg/10mg Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Seram DP 50mg/10mg Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacFondaparinux
Severe
How does the drug interact with Seram DP 50mg/10mg Tablet:
Coadministration of Seram DP 50mg/10mg Tablet with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Seram DP 50mg/10mg Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacLeflunomide
Severe
How does the drug interact with Seram DP 50mg/10mg Tablet:
Co administration of Seram DP 50mg/10mg Tablet with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Seram DP 50mg/10mg Tablet and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacKetorolac
Severe
How does the drug interact with Seram DP 50mg/10mg Tablet:
Coadministration of Seram DP 50mg/10mg Tablet and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of Seram DP 50mg/10mg Tablet and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Seram DP 50mg/10mg Tablet is used in the treatment of pain and inflammation associated with various conditions, such as bone or soft tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea).

Seram DP 50mg/10mg Tablet when taken by patients who are allergic to painkillers can be harmful. It should also be avoided in people with a history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.

You should take Seram DP 50mg/10mg Tablet only if the doctor has prescribed it. The maximum recommended dose of Seram DP 50mg/10mg Tablet is twice daily. Seram DP 50mg/10mg Tablet can be one in the morning and one in the evening.

Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation and pain in the joints.

Ankylosing spondylitis is an arthritis of the spine that can lead to the fusion of the vertebrae, leading to pain and inflammation in the spine.

Yes, Seram DP 50mg/10mg Tablet can cause stomach upset. It should preferably be taken with food to avoid it.

Seram DP 50mg/10mg Tablet should be stored in a cool and dry place, away from direct sunlight. Keep the medicine out of reach of children.

Seram DP 50mg/10mg Tablet is generally safe when used as directed by your physician for short-term relief of pain and inflammation. However, you should not use Seram DP 50mg/10mg Tablet if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, hypertension (high blood pressure), kidney failure, or if you are undergoing dialysis.

Yes, you can stop taking Seram DP 50mg/10mg Tablet once your pain is relieved, but only after consulting your doctor. It is recommended to follow your doctor's advice on the duration and dosage of Seram DP 50mg/10mg Tablet, as stopping the medication too early could affect your recovery.

Yes, the use of Seram DP 50mg/10mg Tablet can cause nausea and vomiting as side effects. Taking it with food may help prevent nausea. If you experience vomiting, try drinking small sips of water or other fluids frequently. If these symptoms persist, please consult your doctor.

Yes, the use of Seram DP 50mg/10mg Tablet may cause dizziness as a side effect in some individuals. Avoid driving or operating machinery if you experience dizziness. If dizziness persists, please consult your doctor.

Yes, Seram DP 50mg/10mg Tablet is contraindicated in patients who are allergic to any of its components, those with kidney failure, or those undergoing dialysis. It should not be taken by patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure). Also, it should be avoided during the last trimester of pregnancy. Please consult your doctor if you have any concerns while using Seram DP 50mg/10mg Tablet.

No, Seram DP 50mg/10mg Tablet is not generally recommended for stomach pain. In fact, it may cause stomach upset, ulcers, or bleeding. If you have stomach pain, please consult your doctor for a proper diagnosis and treatment.

Yes, long-term or high-dose use of Seram DP 50mg/10mg Tablet, a nonsteroidal anti-inflammatory drug (NSAID), can potentially damage the kidneys. Regular monitoring and caution are advised when using Seram DP 50mg/10mg Tablet, especially in individuals with existing kidney disease. Please consult your doctor before using Seram DP 50mg/10mg Tablet.

Yes, Seram DP 50mg/10mg Tablet can be taken on an empty stomach, but it is generally advisable to take Seram DP 50mg/10mg Tablet with food to reduce the risk of side effects. Always follow your doctor's instructions when taking Seram DP 50mg/10mg Tablet.

Seram DP 50mg/10mg Tablet is generally not recommended for children under 10 years of age unless prescribed by a doctor. Always consult a paediatrician before giving Seram DP 50mg/10mg Tablet to a child, as the dosage may need to be adjusted for them.

Seram DP 50mg/10mg Tablet is intended for short-term use only, as it may cause side effects, including gastrointestinal or cardiovascular adverse effects. Always follow your doctor's advice regarding the duration and dosage.

No, it is generally not recommended to consume alcohol while taking Seram DP 50mg/10mg Tablet as it may increase the risk of side effects, such as stomach irritation, ulcers, and bleeding. Your doctor may advise you to limit or avoid alcohol consumption while taking Seram DP 50mg/10mg Tablet.

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