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  3. Seretide 50mcg/100mcg Accuhaler

Seretide 50mcg/100mcg Accuhaler, Pack of 1
Seretide 50mcg/100mcg Accuhaler, Pack of 1
Seretide 50mcg/100mcg Accuhaler, Pack of 1
Seretide 50mcg/100mcg Accuhaler, Pack of 1
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Seretide 50mcg/100mcg Accuhaler is used to treat and prevent respiratory disorders, such as asthma attacks and chronic obstructive pulmonary disease (COPD). It contains Salmeterol and Fluticasone, which relax the muscles in the airways and increase airflow to the lungs. It makes breathing easier by widening the airways. Also, it acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways. It may cause common side effects such as nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

FLUTICASONE-100MCG + SALMETEROL-50MCG

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Seretide 50mcg/100mcg Accuhaler

Seretide 50mcg/100mcg Accuhaler is a respiratory medication used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD). Asthma is a breathing disorder characterised by airway narrowing, swelling, and excessive mucus production, resulting in difficulty breathing. COPD is a group of lung diseases that includes emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of the bronchial tubes).

Seretide 50mcg/100mcg Accuhaler is a combination of two medicines: Salmeterol and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Your doctor will advise on how often you take Seretide 50mcg/100mcg Accuhaler based on your medical condition. The common side effects of Seretide 50mcg/100mcg Accuhaler include nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of Seretide 50mcg/100mcg Accuhaler do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own. Brief your medical history to the doctor if you have heart, liver, kidney diseases, hypokalaemia (low potassium levels in the blood), hyperadrenocorticism (high levels of cortisol), eye disorders like cataract and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes before taking Seretide 50mcg/100mcg Accuhaler. Therapy with nasal or inhaled corticosteroids like Fluticasone should be cautiously administered in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis, since there is a chance of developing a secondary infection. Please check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines.

Uses of Seretide 50mcg/100mcg Accuhaler

Seretide 50mcg/100mcg Accuhaler is used to treat and prevent breathing problems associated with asthma and chronic obstructive pulmonary disease (COPD). The detailed uses of Seretide 50mcg/100mcg Accuhaler are as follows: <br/>• Treatment of asthma: Used to relieve and prevent difficulty breathing, wheezing, shortness of breath, coughing, and chest tightness in people with asthma.<br/>• Management of chronic obstructive pulmonary disease (COPD): Seretide 50mcg/100mcg Accuhaler controls and minimises symptoms such as wheezing, dyspnea, coughing, and chest tightness in patients with COPD, including chronic bronchitis and emphysema.<br/>• Control of COPD flare-ups: Reduces the frequency and severity of COPD exacerbations while improving overall lung function.<br/>• Anti-inflammatory effect: Fluticasone reduces airway irritation, which makes breathing easier.<br/>• Long-acting bronchodilation: Salmeterol relaxes the airway muscles, helping breathing become easier over time.<br/>

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Please read the instruction leaflet and use it as suggested by your doctor.
  • Rinse your mouth with water and spit it out after using Seretide 50mcg/100mcg Accuhaler to avoid fungal infections in the mouth and throat.

Medicinal Benefits

Seretide 50mcg/100mcg Accuhaler is used to treat and prevent respiratory disorders, such as asthma attacks and chronic obstructive pulmonary disease (COPD). Seretide 50mcg/100mcg Accuhaler improves pulmonary function and effectively treats and prevents the worsening of emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Seretide 50mcg/100mcg Accuhaler is a combination of Salmeterol (bronchodilator) and Fluticasone (corticosteroid). Salmeterol relaxes the muscles in the airways, increasing airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways. Fluticasone has potent vasoconstrictive (narrowing of the blood vessels) and anti-inflammatory activity.

How Seretide 50mcg/100mcg Accuhaler Works

Seretide 50mcg/100mcg Accuhaler is a combination of two medicines: Salmeterol (bronchodilator) and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Storage

Keep out of sight and reach of children.

What if I have taken an overdose of Seretide 50mcg/100mcg Accuhaler

Do not use Seretide 50mcg/100mcg Accuhaler in more doses or more often than prescribed, as it may cause an overdose. The symptoms of overdose include chest pain, dry mouth, confusion, decreased urine output, loss of appetite, high blood pressure, nervousness or mood changes. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not stop taking this medicine on your own unless advised by your doctor. Before taking Seretide 50mcg/100mcg Accuhaler, let your doctor know if you have a history of heart, liver, kidney diseases, hyperadrenocorticism (high levels of cortisol), eye disorders like cataracts and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes. Seretide 50mcg/100mcg Accuhaler may cause hypokalemia (low potassium levels in the blood); therefore, it should be used with caution in patients with hypokalaemia to prevent any cardiovascular effects. Special precautions should be taken in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis, since nasal or inhaled corticosteroids like Fluticasone can cause secondary infections. Seretide 50mcg/100mcg Accuhaler can cause a rise in blood glucose levels. Hence, monitor your blood glucose levels regularly if you are diabetic. Please let your doctor know if you plan to become pregnant or are already pregnant and a lactating mother. Do not drive or operate machinery if you experience drowsiness and increased/uneven heart rate while using Seretide 50mcg/100mcg Accuhaler. Avoid drinking alcohol while taking this medicine, as it can worsen your side effects.

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
SalmeterolCarvedilol
Severe

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
Co-administration of Seretide 50mcg/100mcg Accuhaler with Mifepristone may make Seretide 50mcg/100mcg Accuhaler less effective as a therapy.

How to manage the interaction:
Taking Seretide 50mcg/100mcg Accuhaler with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
SalmeterolCarvedilol
Severe
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
Taking Carvedilol and Seretide 50mcg/100mcg Accuhaler may reduce the effects of both medications.

How to manage the interaction:
There may be a possibility of interaction between Seretide 50mcg/100mcg Accuhaler and Carvedilol, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
SalmeterolCocaine
Severe
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
Using Seretide 50mcg/100mcg Accuhaler together with cocaine nasal may occasionally cause irregular heart rhythm.

How to manage the interaction:
Co-administration of Seretide 50mcg/100mcg Accuhaler with Cocaine can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
SalmeterolLabetalol
Severe
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
Co-administration of Labetalol and Seretide 50mcg/100mcg Accuhaler together can decrease the medical benefits of both medications.

How to manage the interaction:
Although taking Labetalol and Seretide 50mcg/100mcg Accuhaler together can result in an interaction, it can be taken if a doctor has prescribed it. Do not forget to inform the doctor if you have severe chronic obstructive pulmonary disease (COPD) or a history of asthma, as labetalol is often not advised in these conditions. Do not discontinue any medications without a doctor's advice.
SalmeterolPenbutolol
Severe
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
The combined use of Penbutolol and Seretide 50mcg/100mcg Accuhaler can decrease the effect of both Seretide 50mcg/100mcg Accuhaler and Penbutolol. It may also increase the risk of severe asthma attacks or breathing problems.

How to manage the interaction:
Co-administration of Seretide 50mcg/100mcg Accuhaler with Penbutolol can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
SalmeterolPindolol
Severe
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
Coadministration of Pindolol with Seretide 50mcg/100mcg Accuhaler can reduce the action of both the drugs. It may increase the risk of severe asthma attacks or breathing problems.

How to manage the interaction:
Although taking Seretide 50mcg/100mcg Accuhaler and Pindolol together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting a doctor.
SalmeterolSaquinavir
Severe
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
Saquinavir may significantly increase the blood levels of Seretide 50mcg/100mcg Accuhaler. High blood levels of Seretide 50mcg/100mcg Accuhaler can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Seretide 50mcg/100mcg Accuhaler and Saquinavir, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SalmeterolPropranolol
Severe
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
Using propranolol together with Seretide 50mcg/100mcg Accuhaler may reduce the benefits of both medications, since they have opposing effects in the body. In addition, propranolol can sometimes cause breathing problems.

How to manage the interaction:
Although taking Propranolol together with Seretide 50mcg/100mcg Accuhaler can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
SalmeterolAmprenavir
Severe
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
Co-administration of Amprenavir and Seretide 50mcg/100mcg Accuhaler together can increase the irregular heart rhythm.

How to manage the interaction:
Although taking Seretide 50mcg/100mcg Accuhaler and Amprenavir together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
SalmeterolAtazanavir
Severe
How does the drug interact with Seretide 50mcg/100mcg Accuhaler:
Using Seretide 50mcg/100mcg Accuhaler together with atazanavir may significantly increase the blood levels and effects of Seretide 50mcg/100mcg Accuhaler.

How to manage the interaction:
Although there is a possible interaction between Seretide 50mcg/100mcg Accuhaler and Atazanavir, you can take these medicines together if prescribed by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Seretide 50mcg/100mcg Accuhaler.
  • Know your triggers, such as allergens, such as pollen, dust, and food items, that make your asthma severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Seretide 50mcg/100mcg Accuhaler Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid drinking alcohol while taking this medicine as it can worsen your side effects.

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Pregnancy

Caution

Please consult your doctor if you are planning to conceive or are already pregnant before starting Seretide 50mcg/100mcg Accuhaler.

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Breast Feeding

Caution

There is limited data on how Seretide 50mcg/100mcg Accuhaler affects breastfeeding. Please consult your doctor before starting Seretide 50mcg/100mcg Accuhaler.

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Driving

Caution

Do not drive or operate machinery if you experience drowsiness and an increased or uneven heart rate while using Seretide 50mcg/100mcg Accuhaler. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Seretide 50mcg/100mcg Accuhaler should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Seretide 50mcg/100mcg Accuhaler.

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Kidney

Caution

Seretide 50mcg/100mcg Accuhaler should be used with caution in patients with kidney diseases. Inform your doctor if you have a history of kidney disease. Your doctor will weigh the benefits and potential risks before prescribing Seretide 50mcg/100mcg Accuhaler.

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Children

Caution

Seretide 50mcg/100mcg Accuhaler is not recommended for use for children less than four years of age. The dose may have to be adjusted by your doctor depending upon the condition of the child's disease and age.

Have a query?

FAQs

Seretide 50mcg/100mcg Accuhaler is used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD).

Seretide 50mcg/100mcg Accuhaler consists of Salmeterol (bronchodilator) and Fluticasone (Fluticasone). Salmeterol relaxes the muscles in the airways, increasing airflow to the lungs. Fluticasone acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways.

Seretide 50mcg/100mcg Accuhaler should be cautiously administered under the doctor's guidance in seizures since bronchodilators like Salmeterol can cause central nervous system stimulation that can lead to other adverse conditions. Please consult your doctor before using Seretide 50mcg/100mcg Accuhaler if you have seizures.

Seretide 50mcg/100mcg Accuhaler contains bronchodilator (Fluticasone), which can cause a rise in blood glucose levels. Hence, therapy with Seretide 50mcg/100mcg Accuhaler is cautiously administered in patients with diabetes. Please monitor your blood glucose levels regularly and inform your doctor so that the dose can be adjusted accordingly.

Bronchodilator (Salmeterol) in Seretide 50mcg/100mcg Accuhaler may decrease the potassium levels in your body; therefore, it should be used with caution. Please consult your doctor before taking Seretide 50mcg/100mcg Accuhaler since low potassium levels can lead to other cardiovascular problems in patients with hypokalaemia.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Seretide 50mcg/100mcg Accuhaler is a combination medication used to treat and prevent respiratory disorders, such as asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients: Salmeterol and Fluticasone Propionate.

Seretide 50mcg/100mcg Accuhaler is a controller medication. It manages and prevents symptoms of asthma and chronic obstructive pulmonary disease (COPD) by keeping the airways open and reducing inflammation. It should be used regularly to be effective, and not to relieve sudden asthma attacks immediately.

Seretide 50mcg/100mcg Accuhaler contains a Fluticasone Propionate, which belongs to the family of medicines known as corticosteroids or steroids (cortisone-like medicines), which helps reduce inflammation in the airways.

Yes, Seretide 50mcg/100mcg Accuhaler may increase heart rate due to the Salmeterol component, which is a long-acting beta2-adrenergic receptor agonist (LABA). This can lead to palpitations, tremors, and increased heart rate in some individuals. Try deep breathing exercises, relaxation techniques, staying hydrated, and avoiding caffeine and nicotine to manage an increased heart rate. If the increased heart rate persists or worsens, consult your healthcare provider for guidance.

Seretide 50mcg/100mcg Accuhaler may cause some common side effects, including nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle, or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of Seretide 50mcg/100mcg Accuhaler do not require medical attention and typically resolve on their own over time. However, if the side effects persist, contact your doctor.

Seretide 50mcg/100mcg Accuhaler is not addictive. It is a very effective and useful medication for people suffering from breathing difficulties due to asthma and COPD.

Taking Seretide 50mcg/100mcg Accuhaler more frequently than prescribed will not make it more effective and can increase the risk of side effects. It is essential to use this medication exactly as directed by your doctor to manage your asthma or COPD effectively.

When using Seretide 50mcg/100mcg Accuhaler, following certain precautions is essential to ensure safe and effective use. Follow your doctor's instructions, and do not use it for sudden asthma attacks. Instead, use a rescue inhaler as your doctor advises. Additionally, rinse your mouth with water after inhaling to prevent fungal infections. Avoid asthma triggers, such as dust, pollen, or smoke, and store the inhaler correctly, out of the reach of children, pets, and extreme temperatures. Inform your doctor about other medications, supplements, or vitamins you're taking, and regularly monitor for side effects, such as increased heart rate, tremors, or mood changes.

Seretide 50mcg/100mcg Accuhaler should be stored below 30°C and kept away from moisture. Keep out of the reach of children. Always follow the storage instructions provided on the packaging or by your healthcare provider.

Country of origin

INDIA

Manufacturer/Marketer address

Dr. Annie Besant Road, Mumbai - 400 030
Other Info - SER0023

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:40 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/dosage/fluticasone-salmeterol.html
  2. https://www.mayoclinic.org/drugs-supplements/fluticasone-and-salmeterol-inhalation-route/description/drg-20063110
  3. https://medlineplus.gov/druginfo/meds/a699063.html

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