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  3. Seroflo 125 Inhaler

Seroflo 125 Inhaler, Pack of 1
Seroflo 125 Inhaler, Pack of 1
Seroflo 125 Inhaler, Pack of 1
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Seroflo 125 Inhaler is used to treat and prevent asthma and chronic obstructive pulmonary diseases (COPD) like bronchitis (inflammation of the lining of your bronchial tubes) and emphysema (shortness of breath). It contains Salmeterol and Fluticasone propionate, which works by relaxing the muscles in the airways and widening the airways. Thus, it makes breathing easier. Also, it stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, provides relief from sneezing, runny or blocked nose and sinus discomfort. It may cause side effect such as headache, stomach upset, dizziness, nervousness, vomiting, respiratory tract infection, fungal infection of the mouth, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle or joint) pain, and increased heart rate. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

FLUTICASONE PROPIONATE-125MCG + SALMETEROL-25MCG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Seroflo 125 Inhaler

Seroflo 125 Inhaler is used to treat and prevent asthma and chronic obstructive pulmonary diseases (COPD) like bronchitis (inflammation of the lining of your bronchial tubes) and emphysema (shortness of breath). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing.

Seroflo 125 Inhaler is a combination of Salmeterol and Fluticasone propionate. Salmeterol works by relaxing the muscles in the airways and widening the airways. Fluticasone propionate works by acting on the nasal lining's inner cells and stopping releasing certain chemicals in the body that cause inflammatory reactions.

Some people may experience headaches, stomach upset, dizziness, nervousness, vomiting, fungal infection of the mouth, hoarseness of voice, sore throat, cough, and increased heart rate. Most of these side effects do not require medical attention. However, if the side effects persist or worsen, please consult your doctor.

Seroflo 125 Inhaler is for inhalation purposes only. Take Seroflo 125 Inhaler by inhaling the number of puffs as your doctor advises. Your doctor will recommend how often you take Seroflo 125 Inhaler based on your medical condition.

Inform your doctor if you are allergic to Seroflo 125 Inhaler or other ingredients. If you are pregnant or breastfeeding, please inform your doctor before using Seroflo 125 Inhaler. Seroflo 125 Inhaler is not recommended for children under 12. Use of Seroflo 125 Inhaler may worsen asthma symptoms in some patients. If you experience severe difficulty breathing, please consult a doctor immediately to prescribe an alternative medicine.

Uses of Seroflo 125 Inhaler

Seroflo 125 Inhaler is used in the treatment of chronic respiratory conditions. The detailed uses of Seroflo 125 Inhaler are as follows:

  • Treatment of asthma: Seroflo 125 Inhaler prevents and manages symptoms like wheezing, coughing, and shortness of breath by relaxing the airway muscles.
  • Management of chronic obstructive pulmonary disease (COPD): Improves airflow and breathing in patients with long-term lung diseases.
  • Treatment of bronchitis: Relieves symptoms of chronic bronchitis by decreasing airway inflammation and enhancing airflow.
  • Management of emphysema: Enhances breathing capacity in patients with emphysema by keeping the air passages open.
  • Long-term maintenance therapy: Provides sustained bronchodilation to minimise the frequency and severity of respiratory problems.

Directions for Use

  • Recommended to take Seroflo 125 Inhaler twice a day or as advised by your doctor.
  • Hold it upright and place the mouthpiece between your teeth without biting it. Breathe in slowly through your mouth and press the top of the inhaler at the same time to release the medicine.
  • Remove the inhaler and hold your breath for a few seconds, then breathe out slowly.
  • Rinse your mouth with water and spit it out after using it to avoid fungal infections in the mouth and throat.

Medicinal Benefits

  • Seroflo 125 Inhaler is used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD).
  • Seroflo 125 Inhaler improves pulmonary function and effectively treats and prevents the worsening of emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). 
  • Seroflo 125 Inhaler is a combination of two drugs: Salmeterol and Fluticasone propionate, which is used to treat asthma symptoms and chronic obstructive pulmonary disease (COPD).
  • Salmeterol belongs to the class of bronchodilators that relax muscles and widen the lungs' airways. Thus, it makes breathing easier.
  • Fluticasone propionate belongs to the class of corticosteroids that work by acting on the nasal lining's inner cells and stopping the release of certain chemicals in the body that cause inflammatory reactions.
  • Seroflo 125 Inhaler provides relief from sneezing, runny or blocked nose and sinus discomfort.

How Seroflo 125 Inhaler Works

Seroflo 125 Inhaler combines two drugs: Salmeterol (bronchodilator) and Fluticasone propionate (corticosteroid). Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widening the airways. Thus, it makes breathing easier. Fluticasone propionate belongs to the class of corticosteroids that work by acting on the nasal lining's inner cells and stopping releasing certain chemicals in the body that cause inflammatory reactions. Thereby providing relief from sneezing, runny or blocked nose and sinus discomfort.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Seroflo 125 Inhaler
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Regular exercise, like swimming, walking, and yoga, can help reduce bone pain by strengthening muscles and releasing natural pain relievers.
  • Physical therapy, including stretching, strengthening exercises, TENS (a type of therapy using electrical pulses), and massage, can help ease bone pain and improve movement.
  • Mind-body techniques, like relaxation, meditation, and hypnosis, can reduce pain and help control muscle tension that comes with bone pain.
  • Acupuncture may help reduce bone pain by triggering the release of natural painkillers and easing nerve discomfort.
  • Avoid sitting for long periods; take short walks or stretch regularly.
  • Herbs like turmeric and ginger might help with bone pain.
  • Eat a diet rich in calcium, vitamin D, and protein for strong bones and muscles.
  • Quit smoking and limit alcohol.

What if I have taken an overdose of Seroflo 125 Inhaler

Do not use Seroflo 125 Inhaler in more doses or more often than prescribed as it may cause serious adverse effects like chest pain, fast/irregular heartbeat, feeling shaky, fits, dizziness, fainting, headache, nervousness, dry mouth, lack of energy, muscle cramps or excessive tiredness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Please tell your doctor if you are allergic to Seroflo 125 Inhaler or other ingredients.
  • If you are pregnant or breastfeeding, please inform your doctor before using Seroflo 125 Inhaler.
  • Seroflo 125 Inhaler is not recommended for children below 12 years of age.
  • Use of Seroflo 125 Inhaler may worsen asthma symptoms in some patients. If you experience severe difficulty breathing, please consult a doctor immediately so that alternative medicine may be prescribed.
  • Contact your doctor if you have blurred vision or any other vision disturbances while taking Seroflo 125 Inhaler.
  • Regular monitoring of potassium levels is recommended while taking Seroflo 125 Inhaler as it may cause low potassium levels in the blood.
  • If you have high blood pressure, diabetes, chest or lungs infection, hyperthyroidism (overactive thyroid), hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), tuberculosis, heart, liver or adrenal gland problems, inform your doctor before taking Seroflo 125 Inhaler.

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
SalmeterolPenbutolol
Severe

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
How does the drug interact with Seroflo 125 Inhaler:
Co-administration of Seroflo 125 Inhaler with Mifepristone may make Seroflo 125 Inhaler less effective as a therapy.

How to manage the interaction:
Taking Seroflo 125 Inhaler with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
SalmeterolPenbutolol
Severe
How does the drug interact with Seroflo 125 Inhaler:
The combined use of Penbutolol and Seroflo 125 Inhaler can decrease the effect of both Seroflo 125 Inhaler and Penbutolol. It may also increase the risk of severe asthma attacks or breathing problems.

How to manage the interaction:
Co-administration of Seroflo 125 Inhaler with Penbutolol can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
SalmeterolLabetalol
Severe
How does the drug interact with Seroflo 125 Inhaler:
Co-administration of Labetalol and Seroflo 125 Inhaler together can decrease the medical benefits of both medications.

How to manage the interaction:
Although taking Labetalol and Seroflo 125 Inhaler together can result in an interaction, it can be taken if a doctor has prescribed it. Do not forget to inform the doctor if you have severe chronic obstructive pulmonary disease (COPD) or a history of asthma, as labetalol is often not advised in these conditions. Do not discontinue any medications without a doctor's advice.
SalmeterolAtazanavir
Severe
How does the drug interact with Seroflo 125 Inhaler:
Using Seroflo 125 Inhaler together with atazanavir may significantly increase the blood levels and effects of Seroflo 125 Inhaler.

How to manage the interaction:
Although there is a possible interaction between Seroflo 125 Inhaler and Atazanavir, you can take these medicines together if prescribed by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
SalmeterolBoceprevir
Severe
How does the drug interact with Seroflo 125 Inhaler:
Co-administration of Boceprevir and Seroflo 125 Inhaler together can increase the irregular heart rhythm.

How to manage the interaction:
Although taking Seroflo 125 Inhaler and Boceprevir together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SalmeterolNefazodone
Severe
How does the drug interact with Seroflo 125 Inhaler:
Nefazodone may significantly increase the blood levels of Seroflo 125 Inhaler. High blood levels of Seroflo 125 Inhaler can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Seroflo 125 Inhaler and Nefazodone, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
SalmeterolLevobunolol
Severe
How does the drug interact with Seroflo 125 Inhaler:
Using levobunolol ophthalmic together with Seroflo 125 Inhaler may reduce the benefits of both medications. It may increase the risk of severe asthmatic attacks or breathing problems.

How to manage the interaction:
There may be a possibility of interaction between Seroflo 125 Inhaler and Levobunolol, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
SalmeterolIndinavir
Severe
How does the drug interact with Seroflo 125 Inhaler:
Indinavir may significantly increase the blood levels of Seroflo 125 Inhaler. High blood levels of Seroflo 125 Inhaler can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Seroflo 125 Inhaler with Indinavir together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SalmeterolTelithromycin
Severe
How does the drug interact with Seroflo 125 Inhaler:
Telithromycin may significantly increase the blood levels of Seroflo 125 Inhaler. High blood levels of Seroflo 125 Inhaler can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Seroflo 125 Inhaler and Telithromycin, you can take these medicines together if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
SalmeterolTroleandomycin
Severe
How does the drug interact with Seroflo 125 Inhaler:
The combined use of Troleandomycin and Seroflo 125 Inhaler can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Seroflo 125 Inhaler with Troleandomycin can result in an interaction, but it can be taken if your doctor has advised it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice, as it may worsen asthma symptoms.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to relieve stress and reduce an asthma attack risk.
  • Quit smoking may reduce the effectiveness of the Seroflo 125 Inhaler and irritate the lungs' worsening breathing problem.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Seroflo 125 Inhaler Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

The interaction of Seroflo 125 Inhaler with alcohol is unknown. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Consult your doctor

The safety of Seroflo 125 Inhaler in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Seroflo 125 Inhaler is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Safe if prescribed

Seroflo 125 Inhaler usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Seroflo 125 Inhaler with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Safe if prescribed

If you have any concerns regarding using Seroflo 125 Inhaler in patients with kidney problems, please consult your doctor.

bannner image

Children

Unsafe

Seroflo 125 Inhaler is not recommended for children below 12 years as the safety and effectiveness were not established. However, please consult a doctor before giving Seroflo 125 Inhaler to children.

Have a query?

FAQs

Seroflo 125 Inhaler is used to treat and prevent asthma and chronic obstructive pulmonary diseases (COPD) like bronchitis (inflammation of the lining of your bronchial tubes) and emphysema (shortness of breath).

Seroflo 125 Inhaler contains salmeterol and Fluticasone propionate. Salmeterol works by relaxing muscles and widening the airways of the lungs. Fluticasone propionate works by acting inside the nasal lining cells and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby relieving sneezing, runny or blocked nose, and sinus discomfort and making breathing easier.

No, you are not recommended to take sotalol with Seroflo 125 Inhaler as it may reduce the effectiveness of both medicines. Also, sotalol may trigger asthma attacks or worsen breathing problems by narrowing airways. However, please consult a doctor before using other medication with a Seroflo 125 Inhaler.

Yes, the Seroflo 125 Inhaler may cause fungal infection in the mouth as a side effect. It is not necessary for everyone taking Seroflo 125 Inhaler to experience this side effect. However, to avoid such side effects, brush your teeth or rinse your mouth with water after using Seroflo 125 Inhaler every time.

Seroflo 125 Inhaler is a combination medicine used to treat and prevent asthma and chronic obstructive pulmonary diseases (COPD) like emphysema (shortness of breath) and bronchitis (inflammation of the lining of your bronchial tubes).

Yes, Seroflo 125 Inhaler contains corticosteroid (Fluticasone propionate) that helps in reducing inflammation in the airways by preventing the release of certain inflammatory chemicals. Thereby, it helps to control symptoms like shortness of breath, wheezing, and inflammation.

Rinse your mouth and/or brush your teeth after using Seroflo 125 Inhaler to prevent oral infections such as thrush and hoarseness. Use Seroflo 125 Inhaler exactly as advised by the doctor to ensure that themedicine works properly in managing your symptoms. Consult the doctor before using other medicines during treatment with Seroflo 125 Inhaler to prevent unpleasant side effects.

You should not stop using Seroflo 125 Inhaler even though you feel better. Stopping Seroflo 125 Inhaler may worsen your symptoms. Continue using Seroflo 125 Inhaler as prescribed by the doctor to get its full benefits.

Seroflo 125 Inhaler is a controller medication. It is designed for long-term use to help control and prevent asthma and COPD symptoms rather than providing immediate relief during an acute attack.

Yes, Seroflo 125 Inhaler may increase heart rate. Seroflo 125 Inhaler contains formoterol, a long-acting beta-agonist (LABA), it opens airways by activating receptors in the lungs. But it can also activate receptors in the heart, which may cause palpitations or a quicker heartbeat in some people.Consult the doctor if you have any concerns.

The side effects of Seroflo 125 Inhaler include nausea, low fever, vomiting or irregular heartbeat,stomach upset, nervousness, muscle and bone pain, sinus pain, sleep problems, chesttightness, vomiting or irregular heartbeat. Consult the doctor if any of these side effects persist or worsen.

No, Seroflo 125 Inhaler is not addictive. It is not a habit-forming medication.

No, Seroflo 125 Inhaler will not be more effective if taken more frequently. Increasing the dosage or frequency can increase the risk of side effects. So, take this medication as prescribed by the doctor.

If you miss a dose take Seroflo 125 Inhaler as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Avoid taking two doses at once.

Seroflo 125 Inhaler should be inhaled by using an inhaler. Hold the inhaler upright and place the mouthpiece between your teeth without biting it. Begin to breathe slowly through your mouth. As you do, press down on the top of the inhaler to release a dose of the medication while continuing to inhale deeply. Once you have finished inhaling, remove the inhaler and hold your breath for as long as is comfortable. Then, breathe out slowly. If a second puff is needed, wait about one minute before repeating these steps. After use, close the mouthpiece with the cover to keep it clean and free from dust.

Consult the doctor before starting Seroflo 125 Inhaler if you are diabetic as the corticosteroid present in this medicine may cause an increase in blood sugar levels. Regularly monitor blood sugar levels while using Seroflo 125 Inhaler.

Seroflo 125 Inhaler can be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - SER0011

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 26, 2025 | 12:30 PM IST

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Reference

  1. https://medlineplus.gov/druginfo/meds/a699063.html
  2. https://www.drugs.com/mtm/fluticasone-inhalation.html
  3. https://www.drugs.com/mtm/fluticasone-and-salmeterol.html

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