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Seroflo 250 Synchrobreathe is used to treat and prevent respiratory disorders, such as asthma attacks and chronic obstructive pulmonary disease (COPD). It contains Salmeterol and Fluticasone, which relax the muscles in the airways and increase airflow to the lungs. It makes breathing easier by widening the airways. It may cause common side effects such as nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Inhalation

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Seroflo 250 Synchrobreathe

Seroflo 250 Synchrobreathe is a maintenance inhalation therapy designed to prevent and manage chronic breathing difficulties. It is commonly prescribed to treat asthma in adults and children, as well as chronic obstructive pulmonary disease (COPD), which includes conditions like emphysema and chronic bronchitis.

To get the best results, you must use Seroflo 250 Synchrobreathe daily and consistently, even on days when you feel your breathing is completely normal. Since this is an inhaled medication, food intake does not affect how it works, but you must always rinse your mouth with water and spit it out after each dose to keep your mouth healthy. Combining this treatment with lifestyle adjustments, such as avoiding environmental tobacco smoke and tracking air quality, can greatly enhance your breathing comfort.

Some people using Seroflo 250 Synchrobreathe may notice mild, temporary side effects, such as throat irritation, hoarseness, or a mild headache. While these are common and often manageable, you must consult your doctor immediately if you experience more serious issues, such as chest pain, a rapid heart rate, or a sudden worsening of your breathing right after taking a dose.

Before starting this treatment, talk to your doctor if you have a history of heart problems, high blood pressure, thyroid disorders, seizures, diabetes, or a weakened immune system. Do not take this if you have a severe allergy to milk proteins (which may be present in certain dry-powder inhalers) or if you have had a severe allergic reaction to any of its components.

Certain medications, such as some blood pressure drugs and strong antifungal treatments, can alter how Seroflo 250 Synchrobreathe works in your body or increase your risk of side effects. If you are pregnant, planning to become pregnant, breastfeeding, or managing multiple health conditions as an older adult, talk to your doctor or pharmacist to ensure this therapy is safe and appropriate for your specific needs.

Uses of Seroflo 250 Synchrobreathe

Seroflo 250 Synchrobreathe is used to prevent and manage chronic breathing difficulties. The detailed uses of Seroflo 250 Synchrobreathe are as follows:

  • Asthma control: Keeps airways open and calm over the long term to prevent sudden shortness of breath and wheezing in patients who require regular combination treatment.
  • Chronic Obstructive Pulmonary Disease (COPD): Helps manage symptoms of long-term lung conditions like chronic bronchitis and emphysema, making daily breathing easier and reducing the frequency of sudden flare-ups.

Key Benefits

Seroflo 250 Synchrobreathe helps improve breathing and supports long-term control of respiratory conditions by keeping the airways open and reducing inflammation. By addressing multiple causes of breathing difficulties, it helps enhance daily comfort and overall lung function.

  • Helps Improve Breathing and Airflow: By relaxing airway muscles and reducing airway narrowing, Seroflo 250 Synchrobreathe helps make breathing easier and reduces symptoms such as wheezing, chest tightness, and shortness of breath.
  • Supports Better Daily Activity and Sleep: Improved airway function can help you perform everyday activities more comfortably and reduce respiratory symptoms that may interfere with restful sleep.
  • Helps Prevent Breathing Flare-Ups: Regular use of Seroflo 250 Synchrobreathe helps reduce the risk of worsening respiratory symptoms and severe exacerbations. This can support better long-term disease control and may reduce the need for emergency medical care or additional rescue medications.
Side effects of Seroflo 250 Synchrobreathe
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest and get enough sleep, and try to give your voice a break.
  • Drink fluids to stay hydrated and to keep your throat moist; avoid caffeine and alcohol.
  • Soothe your throat with warm drinks like tea, broth, or warm water with honey.
  • Gargle with salt water to ease throat pain.
  • Use a humidifier or steam to moisten dry air.
  • Lozenges or hard candy can help soothe a sore throat.
  • Avoid smoke and harsh cleaning products that can irritate your throat.
  • Stay at home until you are feeling better to avoid spreading germs.
  • Lie down or take a nap in dark and quiet room.
  • To avoid dehydration, drink plenty of fluids.
  • In case of mild to moderate migraine, you can take over-the-counter pain relievers like paracetamol or ibuprofen.
  • Apply an ice pack or cool cloth on your forehead.
  • Try relaxation techniques such as yoga, meditation, or deep breathing to reduce stress and relax.
  • Avoid foods and drinks that trigger migraine such as chocolate, alcohol, cheese, caffeine, processed meats, artificial sweeteners and dried fruits.
  • Manage your stress by eating healthy, exercising and a regular sleep schedule.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Please read the instruction leaflet and use it as suggested by your doctor.
  • Rinse your mouth with water and spit it out after using Seroflo 250 Synchrobreathe to avoid fungal infections in the mouth and throat.

How Seroflo 250 Synchrobreathe Works

Seroflo 250 Synchrobreathe is a combination inhaler that delivers two active medicines directly into your lungs. Each component serves a distinct, vital purpose to help improve your breathing. The first component, salmeterol, is a long-acting bronchodilator that helps keep the airways open. It works by relaxing the smooth muscles surrounding the airways, allowing them to widen and improving airflow to and from the lungs. This effect helps make breathing easier and lasts for up to 12 hours. The second component, fluticasone, is an inhaled corticosteroid that helps reduce inflammation in the airways. It works by calming irritation, swelling, and excess mucus production inside the lungs. Over time, this reduces airway sensitivity and helps prevent symptoms from being triggered by factors such as dust, cold air, exercise, or allergens. Together, these two ingredients provide continuous, day-long protection to keep your breathing stable and comfortable.
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Alcohol

Unsafe

Avoid drinking alcohol while taking this medicine as it can worsen your side effects.

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Pregnancy

Consult your doctor

Please consult your doctor if you are planning to conceive or are already pregnant before starting Seroflo 250 Synchrobreathe.

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Breast Feeding

Consult your doctor

There is limited data on how Seroflo 250 Synchrobreathe affects breastfeeding. Please consult your doctor before starting Seroflo 250 Synchrobreathe.

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Driving

Caution

Do not drive or operate machinery if you experience drowsiness and an increased or uneven heart rate while using Seroflo 250 Synchrobreathe. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

The use of Seroflo 250 Synchrobreathe should be exercised with caution in patients with liver disease. Let your doctor know if you have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Seroflo 250 Synchrobreathe.

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Kidney

Caution

Seroflo 250 Synchrobreathe should be used with caution in patients with kidney diseases. Inform your doctor if you have a history of kidney disease. Your doctor will weigh the benefits and potential risks before prescribing Seroflo 250 Synchrobreathe.

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Children

Caution

Seroflo 250 Synchrobreathe is not recommended for use for children less than four years of age. The dose may have to be adjusted by your doctor depending upon the condition of the child's disease and age.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Seroflo 250 Synchrobreathe. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Caution

Seroflo 250 Synchrobreathe should be used in elderly patients only when prescribed by a doctor. If you have any concerns about using Seroflo 250 Synchrobreathe in older adults, please consult your doctor.

What if I have taken an overdose of Seroflo 250 Synchrobreathe

If you suspect an overdose or experience severe symptoms like an unusually rapid heartbeat, extreme shakiness, chest pain, or a feeling of intense anxiety after taking too much medication, seek immediate medical attention or contact a local poison control centre.

Diet & Lifestyle Advise

  • Identify and avoid personal breathing triggers, such as tobacco smoke, dust, pollen, pet dander, and cold air.
  • Drink plenty of water throughout the day to help thin the mucus in your lungs and keep your throat moist.
  • Incorporate moderate, doctor-approved exercise into your routine to help strengthen your heart and breathing muscles.
  • Monitor your local air quality and limit outdoor activities on days when pollution or pollen levels are high.
  • Stay up to date with your annual flu vaccine and ask your healthcare provider about pneumococcal vaccines to protect your lungs from infections.

Have a query?

How Soon It Starts Working

  • The time required for Seroflo 250 Synchrobreathe to start to work: The time required for Seroflo 250 Synchrobreathe to show its action is not clinically established.
  • The time for which the effects of Seroflo 250 Synchrobreathe last: The duration of action for Seroflo 250 Synchrobreathe is not clinically established.

What if you forget to take Seroflo 250 Synchrobreathe

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular routine. Do not take a double dose to make up for a missed one.

Storage

•Store Seroflo 250 Synchrobreathe at room temperature, ideally between 20°C to 25°C (68°F to 77°F). •Keep the inhaler in a dry place, away from direct sunlight, extreme heat, or freezing conditions.

Drug Warnings

  • Never use Seroflo 250 Synchrobreathe as a rescue inhaler to treat a sudden, acute asthma attack. Always carry your fast-acting rescue inhaler with you for emergencies.
  • Rinse your mouth with water and spit it out after every single use to dramatically lower your risk of developing oral thrush.
  • Regularly check the dose counter on your inhaler so you can refill your prescription before the device runs completely empty.
  • Keep the mouthpiece clean by wiping it with a dry tissue or cloth once a week; never wash a dry-powder inhaler with water.
  • If you find yourself needing to use your rescue inhaler more than twice a week (excluding before exercise), talk to your doctor, as your treatment plan may need to be adjusted.

Drug-Drug Interactions

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  • Beta-blockers (certain blood pressure and heart medicines): May block the active effects of Seroflo 250 Synchrobreathe, which can cause your airways to narrow suddenly.
  • Strong antifungal medicines (such as ketoconazole) and certain HIV drugs: Can slow down how your body clears Seroflo 250 Synchrobreathe, which may increase the risk of steroid-related side effects.
  • Diuretics (water pills): When taken with Seroflo 250 Synchrobreathe, these can lower the potassium levels in your blood, which might affect your heart rhythm or muscle strength.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Seroflo 250 Synchrobreathe when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[RESPIRATORY STIMULANTS]

FAQs

Seroflo 250 Synchrobreathe is used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD).
Seroflo 250 Synchrobreathe consists of Salmeterol (bronchodilator) and Fluticasone (Fluticasone). Salmeterol relaxes the muscles in the airways, increasing airflow to the lungs. Fluticasone acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways.
Seroflo 250 Synchrobreathe should be cautiously administered under the doctor's guidance in seizures since bronchodilators like Salmeterol can cause central nervous system stimulation that can lead to other adverse conditions. Please consult your doctor before using Seroflo 250 Synchrobreathe if you have seizures.
Seroflo 250 Synchrobreathe contains bronchodilator (Fluticasone), which can cause a rise in blood glucose levels. Hence, therapy with Seroflo 250 Synchrobreathe is cautiously administered in patients with diabetes. Please monitor your blood glucose levels regularly and inform your doctor so that the dose can be adjusted accordingly.
Bronchodilator (Salmeterol) in Seroflo 250 Synchrobreathe may decrease the potassium levels in your body; therefore, it should be used with caution. Please consult your doctor before taking Seroflo 250 Synchrobreathe since low potassium levels can lead to other cardiovascular problems in patients with hypokalemia.
Seroflo 250 Synchrobreathe is a combination medication used to treat and prevent respiratory disorders, such as asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients: Salmeterol and Fluticasone Propionate.
Seroflo 250 Synchrobreathe contains a Fluticasone Propionate, which belongs to the family of medicines known as corticosteroids or steroids (cortisone-like medicines), which helps reduce inflammation in the airways.
Seroflo 250 Synchrobreathe may cause some common side effects, including nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle, or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of Seroflo 250 Synchrobreathe do not require medical attention and typically resolve on their own over time. However, if the side effects persist, contact your doctor.
Seroflo 250 Synchrobreathe is not addictive. It is a very effective and useful medication for people suffering from breathing difficulties due to asthma and COPD.
Taking Seroflo 250 Synchrobreathe more frequently than prescribed will not make it more effective and can increase the risk of side effects. It is essential to use this medication exactly as directed by your doctor to manage your asthma or COPD effectively.
When using Seroflo 250 Synchrobreathe, following certain precautions is essential to ensure safe and effective use. Follow your doctor's instructions, and do not use it for sudden asthma attacks. Instead, use a rescue inhaler as your doctor advises. Additionally, rinse your mouth with water after inhaling to prevent fungal infections. Avoid asthma triggers, such as dust, pollen, or smoke, and store the inhaler correctly, out of the reach of children, pets, and extreme temperatures. Inform your doctor about other medications, supplements, or vitamins you're taking, and regularly monitor for side effects, such as increased heart rate, tremors, or mood changes.
Seroflo 250 Synchrobreathe should be stored below 30°C and kept away from moisture. Keep out of the reach of children. Always follow the storage instructions provided on the packaging or by your healthcare provider.
No, Seroflo 250 Synchrobreathe is a controller inhaler designed for daily preventive use. It does not work quickly enough to stop an active, sudden asthma attack. You must always use your fast-acting rescue inhaler for immediate relief during a sudden breathing flare-up. Talk to your doctor.
Rinsing your mouth and spitting the water out helps remove any medication residue left in your mouth and throat. This simple step prevents oral thrush (a fungal yeast infection) and keeps your throat from becoming hoarse or irritated. Talk to your doctor.
You may notice some improvement in your breathing within a few days of starting Seroflo 250 Synchrobreathe, but it can take several weeks of regular daily use to experience the full benefits. Consistency is key. Talk to your doctor.
No, you should not stop taking Seroflo 250 Synchrobreathe unless your doctor tells you to. This medication works over the long term to prevent symptoms from returning. If you stop using it, your airway swelling and breathing difficulties are likely to return. Talk to your doctor.
Take your missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your normal routine. Never double the dose to catch up. Talk to your doctor.
Yes, the airway-opening medicine in Seroflo 250 Synchrobreathe can sometimes cause a temporary fast heart rate, palpitations, or mild trembling in the hands. These symptoms are usually mild and improve as your body gets used to the medication. If they are severe or persist, talk to your doctor.
You should discuss your specific situation with your healthcare provider. Your doctor will weigh the benefits of keeping your breathing well-controlled against any potential risks to your baby before recommending this medication. Talk to your doctor.
Most Seroflo 250 Synchrobreathe inhalers feature a built-in dose counter that shows exactly how many puffs are left. When the counter reaches zero or shows a warning colour like red, the device is empty, and you should switch to a new one. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - SER0577
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