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compositionComposition:SERTRALINE-25MG
prescription
Prescription Medicine
info
Serta 25 Tablet 15's
Serta 25 Tablet 15's
Serta 25 Tablet 15's
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SERTRALINE-25MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Serta 25 Tablet

Serta 25 Tablet is an oral prescription medication primarily used to treat depression, panic attacks, obsessive-compulsive disorder, and post-traumatic stress disorder. It helps restore the natural chemical balance in your brain to improve your mood, sleep, appetite, and energy levels. This medicine belongs to a class of drugs widely prescribed by mental health professionals to help manage ongoing emotional distress.

To achieve the best results, you should take Serta 25 Tablet consistently at the same time every day, either with or without food. Establishing a regular daily routine helps maintain a steady level of the medication in your body. Combining this treatment with healthy daily habits, such as regular light exercise and structured sleep routines, can significantly support your progress.

While taking Serta 25 Tablet , some people may experience mild, temporary side effects like nausea, dry mouth, or trouble sleeping, which usually fade within a few weeks. However, you must contact your doctor immediately if you notice any severe changes in your mood, severe dizziness, or signs of an allergic reaction. Your healthcare provider is your best resource for managing any unexpected physical or emotional changes.

Talk to your doctor before starting Serta 25 Tablet if you have a history of seizures, liver damage, heart problems, or bipolar disorder. Do not take this if you are currently taking monoamine oxidase inhibitors (MAOIs) or pimozide, as combining these can lead to dangerous, life-threatening reactions. Only a qualified healthcare professional can determine if this medication is safe for your specific medical history.

This medicine can interact with alcohol, which can significantly worsen drowsiness and coordination, so it is highly recommended to avoid alcoholic drinks during treatment. You should also consult your doctor if you are pregnant, planning to become pregnant, breastfeeding, or if you are an older adult, as these situations require specialized medical guidance.

Uses of Serta 25 Tablet

Serta 25 Tablet is used in the treatment of depression, anxiety, and certain mood-related disorders. The detailed uses of Serta 25 Tablet are as follows:

  • Major Depressive Disorder: It helps relieve persistent feelings of sadness, restores interest in daily activities, and improves overall energy levels.
  • Obsessive-Compulsive Disorder (OCD): It assists in reducing persistent, unwanted thoughts and the urge to perform repetitive, compulsive actions.
  • Panic Disorder: It helps decrease the frequency and intensity of sudden, unexpected panic attacks and reduces the constant fear of future attacks.
  • Post-Traumatic Stress Disorder (PTSD): It helps alleviate severe anxiety, intrusive memories, and hyper-awareness triggered by traumatic events.
  • Social Anxiety Disorder: It reduces extreme self-consciousness, fear, and avoidance of social situations, helping you feel more comfortable around others.
  • Premenstrual Dysphoric Disorder (PMDD): It helps stabilize severe mood swings, irritability, and physical discomfort associated with the premenstrual cycle.

Key Benefits

Serta 25 Tablet helps improve emotional well-being by reducing symptoms of depression, anxiety, and related mental health conditions. By supporting a more balanced mood, it can help you feel more in control of your thoughts, emotions, and daily activities. Benefits may include:

  • Helps reduce feelings of depression, sadness, and hopelessness.
  • Relieves anxiety, excessive worry, and nervousness.
  • Helps manage panic symptoms and improves confidence in social situations.
  • Reduces repetitive thoughts and compulsive behaviours associated with certain anxiety disorders.
  • Supports healthier sleep patterns, appetite, and overall emotional balance.
  • Improves daily functioning, relationships, and overall quality of life.
Side effects of Serta 25 Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Directions for Use

  •  Swallow the tablet whole with a full glass of water. Do not chew, crush, or break the tablet, as this can affect how the medicine is absorbed into your system.
  • You may take this medication with or without food.
  • Take your dose at the same time every day to maintain a consistent amount of the medicine in your body.
  • Always follow your doctor's exact instructions regarding your dose and schedule. Never stop taking this medication suddenly without consulting your healthcare provider first.

How Serta 25 Tablet Works

Serta 25 Tablet works by targeting specific chemical messengers in the brain, with a primary focus on a chemical called serotonin. Serotonin plays a critical role in regulating your mood, sleep, emotions, and overall sense of well-being. In individuals experiencing depression or anxiety, active serotonin levels in the brain may be lower than normal. This medication acts as a selective serotonin reuptake inhibitor (SSRI). It works by blocking brain cells from reabsorbing serotonin after it is released. By preventing this reabsorption, more serotonin remains active in the gaps between brain cells, which strengthens communication between nerves and helps restore emotional balance.
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Alcohol

Unsafe

Avoid consumption of alcohol with Serta 25 Tablet as it may increase the risk of drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Serta 25 Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy especially in the last 3 months as it may cause a serious condition in the baby such as persistent pulmonary hypertension of the newborn (PPHN) which causes the baby to appear bluish and makes breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Serta 25 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Serta 25 Tablet is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Unsafe

Serta 25 Tablet may cause dizziness, drowsiness or impair thinking. Therefore, avoid driving if you experience any of these symptoms after taking Serta 25 Tablet .

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Liver

Caution

Take Serta 25 Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Serta 25 Tablet in patients with kidney problems, please consult a doctor.

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Children

Consult your doctor

Serta 25 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years. Serta 25 Tablet is not recommended to treat any other disorders in children below 18 years of age.

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Heart

Safe if prescribed

Serta 25 Tablet is safe for use in heart patients if prescribed by the physician.

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Geriatrics

Safe if prescribed

Serta 25 Tablet can be safely given in elderly patients if recommended by the physician.

What if I have taken an overdose of Serta 25 Tablet

If you or someone else takes more than the prescribed dose of this medicine, seek immediate medical attention or contact a poison control center right away. Symptoms of an overdose can include extreme sleepiness, severe nausea, vomiting, a rapid heart rate, or shaking.

Diet & Lifestyle Advise

  • Limit or avoid alcohol: Drinking alcohol while taking this medicine can severely increase drowsiness, impair your coordination, and reduce the effectiveness of your treatment.
  • Stay well-hydrated: Drink plenty of water throughout the day, as some medications in this class can cause mild dehydration or lower sodium levels, particularly in older adults.
  • Maintain a consistent sleep routine: Go to bed and wake up at the same times every day, and limit caffeine intake in the afternoon and evening to support better sleep quality.
  • Incorporate regular light exercise: Activities like walking, swimming, or gentle yoga can help boost natural endorphins and work alongside your medication to improve mood.
  • Eat balanced meals: Eating small, regular meals can help manage initial, mild side effects such as nausea or changes in appetite.

Health Queries

I am a student experiencing a lot of stress and pressure; what medicine should I take to control it?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

As a student, experiencing stress is common, but I strongly advise against self-medicating. There is no safe, over-the-counter 'quick-fix' medication for general stress. First, try lifestyle adjustments: ensure 7-8 hours of sleep, exercise regularly, and practice deep-breathing techniques. I highly recommend speaking with a school counselor or a primary care doctor. If your stress is severely impacting your daily life, a healthcare professional can properly evaluate you and discuss therapy options or, if clinically appropriate, prescribe specific medications like beta-blockers for situational anxiety. Please do not start any prescription psychiatric medication without direct medical supervision.

I have been taking antidepressant medicines for the past 3 years. Recently, I have been experiencing low mood, reduced sexual desire, and lack of energy. What could be the reason and what should I do?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

If you have been taking antidepressant medicines for a long time, symptoms like low mood, reduced sexual desire, and lack of energy can sometimes occur as side effects of the medication or due to the underlying depression itself. It may also happen if the current medicine or dose is no longer the most suitable for you. Do not stop the medicine suddenly, as this can worsen symptoms. It is best to consult your doctor or psychiatrist, who may adjust the dose, change the medication, or suggest counseling or lifestyle measures such as regular exercise, good sleep, and stress management to help improve your mood and energy levels.

I am suffering from anxiety, depression, and sleep problems. I am currently taking allopathic medicines, but whenever I stop them, the symptoms return. What is the best way to manage this condition long term?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Anxiety, depression, and sleep problems often need long-term management, and it is common for symptoms to return if medicines are stopped suddenly. These medicines should only be reduced gradually under a doctor's guidance. The best approach is a combination of treatment methods, including regular follow-ups with a psychiatrist, counseling or therapy, good sleep habits, regular exercise, stress-management techniques such as meditation or breathing exercises, and maintaining a healthy routine. With proper medical guidance and lifestyle changes, many people are able to control symptoms well.

I have severe gas problems in the stomach, headaches, and high blood pressure (around 150/97). My doctor says it may be related to depression. I have been taking antidepressants and antacids for the past 9 months, but I have only seen about 20% improvement and feel dependent on the pills. What is the best treatment approach?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Severe gas, headaches, and high blood pressure (around 150/97) can sometimes be linked to stress, anxiety, or depression, but they may also have physical causes such as acidity, diet issues, or uncontrolled BP. If you have only had about 20% improvement after 9 months of treatment, it would be a good idea to review your treatment plan with your doctor or seek a second opinion. Medicines for depression should not be stopped suddenly, as this can worsen symptoms. Along with medication, lifestyle changes such as regular exercise, good sleep, stress-management techniques (like meditation or breathing exercises), and avoiding very spicy or gas-forming foods can help. A gastroenterologist or psychiatrist may help adjust your treatment so you get better relief and gradually reduce dependence on medicines under medical guidance.

Have a query?

How Soon It Starts Working

  • The time required for Serta 25 Tablet to start to work: The time required for Serta 25 Tablet to show its action is unknown.
  • The time for which the effects of Serta 25 Tablet last: The duration of action for Serta 25 Tablet is unknown.

What if you forget to take Serta 25 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular timing. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid driving if you feel dizzy: Do not drive, operate machinery, or perform tasks requiring sharp mental focus until you know how this medication affects you.
  • Check liquid clarity: If using the liquid concentrate form, make sure the solution is clear and colorless before mixing and taking it. Do not use it if it is cloudy or changed in color.
  • Monitor for mood and behavior changes: Serta 25 Tablet may increase the risk of suicidal thoughts, self-harming behavior, or unusual changes in mood, particularly in children, adolescents, and young adults during the first few weeks of treatment or after a dose adjustment.
  • Ensure close supervision in younger patients: Children and adolescents taking Serta 25 Tablet should be monitored regularly by a specialist to assess treatment response and watch for any behavioral or emotional changes.
  • Do not stop treatment abruptly: Do not stop taking Serta 25 Tablet suddenly, as this may cause withdrawal symptoms such as dizziness, headache, nausea, anxiety, sleep disturbances, or tingling sensations. Your doctor may gradually reduce the dose before stopping treatment.
  • Contact your doctor if symptoms persist or worsen: Speak with your healthcare provider if your symptoms do not improve, become worse, or if side effects interfere with your daily activities.
  • Seek urgent medical attention for serious reactions: Get immediate medical help if you experience thoughts of self-harm, symptoms of serotonin syndrome, severe allergic reactions, unusual bleeding, seizures, or loss of consciousness.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Monoamine Oxidase Inhibitors (MAOIs): Taking these together can cause a dangerous, life-threatening condition called serotonin syndrome. Do not take Serta 25 Tablet within 14 days of using an MAOI.
  • Blood thinners (e.g., warfarin): Taking these medicines alongside Serta 25 Tablet may increase the risk of bruising, bleeding, or internal bleeding.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., aspirin, ibuprofen, naproxen): Combining these with Serta 25 Tablet may increase the risk of stomach bleeding, ulcers, and other bleeding-related complications.
  • Triptans and other SSRIs: Taking this with other medicines that raise serotonin levels (like certain migraine drugs or other antidepressants) increases the risk of severe serotonin-related side effects.

Drug-Food Interactions

  • Grapefruit juice: Avoid consuming large quantities of grapefruit juice, as it can interfere with how your body breaks down this medication, potentially raising drug levels in your blood.
  • Alcohol: Avoid alcoholic beverages completely, as alcohol can dangerously increase the sedative effects of this medicine.

Drug-Disease Interactions

  • Liver damage: If you have liver problems, your body may process this medicine more slowly, which may require your doctor to adjust your dose.
  • Seizure disorders: This medicine should be used with extreme caution if you have a history of epilepsy, as it may increase the risk of seizures.
  • Bipolar disorder: This medication can sometimes trigger manic episodes in individuals who have undiagnosed bipolar disorder.
SertralineTranylcypromine
Critical
SertralineIsocarboxazid
Critical

Drug-Drug Interactions

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SertralineTranylcypromine
Critical
How does the drug interact with Serta 25 Tablet:
Taking Tranylcypromine and Serta 25 Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine and Serta 25 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineIsocarboxazid
Critical
How does the drug interact with Serta 25 Tablet:
Co-administration of Serta 25 Tablet with Isocarboxazid can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Isocarboxazid with Serta 25 Tablet there may be a possibility of interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineEliglustat
Critical
How does the drug interact with Serta 25 Tablet:
Coadministration of Eliglustat and Serta 25 Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Eliglustat and Serta 25 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineThioridazine
Critical
How does the drug interact with Serta 25 Tablet:
Co-administration of Thioridazine and Serta 25 Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Thioridazine and Serta 25 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations -contact a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineZiprasidone
Critical
How does the drug interact with Serta 25 Tablet:
Co-administration of Serta 25 Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Serta 25 Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SertralineDronedarone
Critical
How does the drug interact with Serta 25 Tablet:
Co-administration of Dronedarone and Serta 25 Tablet may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dronedarone with Serta 25 Tablet is not recommend, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
SertralineLinezolid
Critical
How does the drug interact with Serta 25 Tablet:
When linezolid is taken with Serta 25 Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
taking Linezolid and Serta 25 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineProcarbazine
Critical
How does the drug interact with Serta 25 Tablet:
When Procarbazine is taken with Serta 25 Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Serta 25 Tablet and Procarbazine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineSelegiline
Critical
How does the drug interact with Serta 25 Tablet:
Co-administration of Serta 25 Tablet with Selegiline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selegiline with Serta 25 Tablet together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralinePimozide
Critical
How does the drug interact with Serta 25 Tablet:
Taking Serta 25 Tablet with pimozide can increase the risk of heart rhythm problems.

How to manage the interaction:
There may be a possibility of interaction between Pimozide and Serta 25 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs -dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations-call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

Serta 25 Tablet used in the treatment of Depression, Post-traumatic stress disorder (PTSD), Social anxiety disorder, Panic disorder, and Obsessive-compulsive disorder (OCD).

Yes, Serta 25 Tablet may be used to treat a panic disorder by reducing fear. However, please consult a doctor before using the Serta 25 Tablet .

No, you are not recommended to take Serta 25 Tablet with opioids as co-administration of these medicines may cause adverse effects such as hallucinations, increased muscle tension, excessive sweating, fever, anxiety, involuntary, rhythmic contractions of muscles, including the muscles that control eye movement, tremor or even coma. However, before using Serta 25 Tablet with any other medicines, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

Yes, Serta 25 Tablet may cause self-harming or suicidal thoughts, especially in patients aged less than 25 years or who have a history of self-harming thoughts. Therefore, please consult a doctor immediately if you experience any such thoughts while taking Serta 25 Tablet .

The duration of treatment varies from person to person. Many individuals continue treatment for at least 6 to 12 months after their symptoms improve. Some people may require longer treatment to prevent symptoms from returning. Your doctor will determine the most appropriate treatment duration based on your condition and progress.

Serta 25 Tablet may affect male fertility as it may reduce sperm quality. Therefore, please consult a doctor if you are planning to father a child.

Serta 25 Tablet should be used with caution in diabetic patients as it may alter blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Serta 25 Tablet , especially if you have diabetes, and the dose of diabetic medicines may be adjusted appropriately by your doctor.

Serta 25 Tablet contains Sertraline, which inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases the serotonin (chemical messenger) activity in the brain that regulates mood, behaviour and emotions. Thereby, Serta 25 Tablet helps in relieving depression, lightening the mood and relieving anxiety symptoms such as fear and panic.

The side effects of Serta 25 Tablet include nausea, headache, diarrhoea, tiredness, drowsiness, dizziness and insomnia (difficulty sleeping). If these side effects persist or worsen, please consult your doctor.

You are recommended to take Serta 25 Tablet for as long as it is prescribed by your doctor, which may be for several months. Do not stop taking Serta 25 Tablet before the advised time as it may cause depression to recur.

Take Serta 25 Tablet as advised by your doctor. It can be taken with or without food at any time of the day and is usually taken once a day. Take it as per your convenience but preferably at the same time every day. Some people should take it in the morning who have sleep difficulty after taking Serta 25 Tablet . Whereas, some take it at night to minimize the side effects of vomiting and nausea.

Yes, mild drowsiness or fatigue is a common side effect, especially during the first few weeks of starting the medication. If it makes you feel sleepy during the day, your doctor may suggest taking your daily dose in the evening. Talk to your doctor to find the best dosing schedule.

Serta 25 Tablet increases the serotonin levels which is an important chemical and a neurotransmitter. This helps to improve and regulate mood, resulting in an improvement in the anxiety symptoms.

No, you should not stop taking this medication on your own, even if you feel fine. Stopping suddenly can cause withdrawal symptoms like dizziness, irritability, and headache. Your doctor will help you gradually decrease your dose when it is safe to stop. Talk to your doctor before making any changes.

The withdrawal symptoms of Serta 25 Tablet include numbness or tingling in the hands or feet, dizziness, nausea, trouble sleeping, headaches, feeling agitated or anxious, and shaking. However, these symptoms are usually mild to moderate and disappear 1-2 weeks after stopping Serta 25 Tablet .

The symptoms of Serta 25 Tablet overdose include fever, nausea, vomiting, dizziness, confusion, shakiness, and a rapid heartbeat. Whereas, serious side effects include heart problems, fainting, delirium, and changes in blood pressure. If you experience such symptoms, contact your doctor immediately.

Weight changes can vary; some people experience a mild decrease in appetite or temporary weight loss when starting the medicine due to mild nausea, while others may experience weight gain over long-term use. Talk to your doctor if you have concerns about weight changes during your treatment.

The decision to use Serta 25 Tablet during pregnancy requires careful consideration of both the benefits and potential risks. Untreated depression, anxiety, and other mental health conditions can also affect the health of both the mother and baby. Your doctor will carefully assess your individual situation and discuss the most appropriate treatment approach. If you are pregnant, planning a pregnancy, or become pregnant while taking Serta 25 Tablet , contact your doctor as soon as possible.

Moderate caffeine intake is generally safe, but because caffeine can worsen anxiety symptoms and disrupt sleep, it is best to limit your intake, especially in the afternoon. Talk to your doctor if you experience increased jitteriness or trouble sleeping.

You should use caution when taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, as they can increase the risk of stomach bleeding when combined with this medicine. Acetaminophen is generally a safer option for pain relief. Talk to your doctor or pharmacist for advice.

Sexual side effects, such as a decreased sex drive or difficulty reaching orgasm, are recognized side effects of this class of medication. These symptoms often persist during treatment but can be managed by adjusting your dose or exploring other treatment options. Talk to your doctor to find a comfortable solution.

Stopping Serta 25 Tablet abruptly can cause discontinuation symptoms such as dizziness, nausea, headache, anxiety, sleep disturbances, vivid dreams, irritability, and tingling sensations. Your doctor will usually recommend gradually reducing the dose over time to help minimize these effects.

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.10586 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Sertraline Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. National Health Service (NHS). Sertraline - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Singh HK, Saadabadi A Sertraline. [Updated 2023 Feb 13]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Check here
  5. Kornstein SG, Pearlstein TB, Fayyad R, Farfel GM, Gillespie JA Kornstein SG, Pearlstein TB, Fayyad R, Farfel GM, Gillespie JA. 2006. [Accessed on 06 Aug. 2023] Check here
  6. Sertraline Hydrochloride [Prescribing Information]. 2023. [Accessed on 06 Aug. 2023] Check here
  7. emc Sertraline. [[Accessed on 26.Aug].2019]Check here

Country of origin

India

Manufacturer/Marketer address

Unichem Laboratories Ltd., Unichem Bhavan, Prabhat Estate, Off S.V.Road, Jogeshwari (West), Mumbai – 400 102
Other Info - SER0017

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