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Sevelar 400 mg Tablet 10's

Manufacturer/Marketer

NEPHUROCARE PHARMA PVT LTD

Composition

SEVELAMER-100MCG

Consume Type

ORAL

In Stock

Prescription Required
Product Details

About Sevelar 400 mg Tablet 10's

Sevelar 400 mg Tablet 10's belongs to a group of medications called 'phosphate binder' (which decrease the level of phosphate in the body). It is primarily used to control high phosphate levels in the body (hyperphosphataemia) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used for the treatment of bone disease.

Sevelar 400 mg Tablet 10's contains 'sevelamer' that works by binding phosphate in the gastrointestinal tract and decreasing absorption. It effectively reduces excess phosphate levels in the blood, prevents the unsafe build-up of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes.

Take Sevelar 400 mg Tablet 10's exactly as directed by your doctor. The most common side effects of Sevelar 400 mg Tablet 10's are vomiting, upper abdominal pain, nausea, diarrhoea, stomach ache, indigestion, and flatulence. Although, not every person faces the side effects of Sevelar 400 mg Tablet 10's, and even some of the unpleasant effects of Sevelar 400 mg Tablet 10's do not require medical attention. However, if the side effects are persistent, reach out to your doctor.

The use of Sevelar 400 mg Tablet 10's is restricted in persons with a known history of allergic to any of the ingredients present in this medicine, have low levels of phosphate in their blood, and have a bowel obstruction. Sevelar 400 mg Tablet 10's contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Sevelar 400 mg Tablet 10's. Tell your doctor if you are facing swallowing problems, motility (movement) in your stomach and bowel, being sick frequently, active inflammation of the bowel,  have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. If you are pregnant or breastfeeding, please consult your doctor before taking Sevelar 400 mg Tablet 10's.

Uses of Sevelar 400 mg Tablet 10's

Hyperphosphatemia (high phosphorus level in blood)

Medicinal Benefits

Sevelar 400 mg Tablet 10's belongs to a group of medications called 'phosphate binder', which works by binding phosphate in the gastrointestinal tract and decreasing its absorption. This lowers the phosphate concentration in the body. It effectively reduces excess phosphate levels in the blood, prevents the unsafe buildup of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes. Sevelar 400 mg Tablet 10's controls hyperphosphataemia (high blood phosphate levels) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine) or peritoneal dialysis (where the fluid is pumped into the abdomen and an internal body membrane filters the blood), and patients with chronic kidney disease.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sevelar 400 mg Tablet 10's

  • Headache
  • Diarrhoea
  • Stomach upset
  • Constipation

In-Depth Precautions and Warning

Drug Warnings

You should avoid taking Sevelar 400 mg Tablet 10's if you are allergic to Sevelar 400 mg Tablet 10's. Speak to your doctor if you have swallowing disorders, digestive tract surgery, severe constipation, have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. It should be used with caution if you are pregnant or planning to become pregnant. Sevelar 400 mg Tablet 10's should not be recommended for breastfeeding mothers as it passes into breast milk. Avoid alcohol consumption while taking Sevelar 400 mg Tablet 10's as it might cause unpleasant side effects. The safety and effectiveness of children under six years of age have not been established, so a Sevelar 400 mg Tablet 10's should not be given to them. Sevelar 400 mg Tablet 10's contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Sevelar 400 mg Tablet 10's. Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is advised while taking Sevelar 400 mg Tablet 10's.

Drug Interactions

Drug-Drug Interactions: Sevelar 400 mg Tablet 10's interact with antibiotics (ciprofloxacin), immunosuppressive agents (mycophenolate), thyroid medications  (levothyroxine), and medication is used to treat bladder cancer (erdafitinib).

Drug-Food Interactions: Avoid taking high-phosphate additives and alcohol as this makes it harder for your body to absorb Sevelar 400 mg Tablet 10's and increases side effects. Using Sevelar 400 mg Tablet 10's together with multivitamin with minerals may decrease the effects of multivitamin with minerals. So, Multivitamin with minerals should be administered at least 4 hours before Sevelar 400 mg Tablet 10's.

Drug-Disease Interactions: The use of Sevelar 400 mg Tablet 10's is restricted in people with hypophosphatemia (low phosphate level in blood), bowel obstruction and perforation, and severe liver disease.

Drug-Drug Interactions Checker List:

  • CIPROFLOXACIN
  • MYCOPHENOLATE SODIUM
  • LEVOTHYROXINE SODIUM
  • ERDAFITINIB
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended to avoid alcohol consumption while taking Sevelar 400 mg Tablet 10's to avoid unpleasant side-effects.

    • Safety Warning

      Pregnancy

      caution

      Sevelar 400 mg Tablet 10's is Category C pregnancy medicine. Please consult your doctor if you have any concerns; your doctor will prescribe you Sevelar 400 mg Tablet 10's only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      The safety of Sevelar 400 mg Tablet 10's has not been established in breastfeeding women. Please consult your doctor if you have any concerns regarding this; your doctor will decide whether the Sevelar 400 mg Tablet 10's can be given to breastfeeding mothers or not.

    • Safety Warning

      Driving

      safe if prescribed

      Sevelar 400 mg Tablet 10's has no or negligible influence on the ability to drive or operate any machinery.

    • Safety Warning

      Liver

      caution

      Sevelar 400 mg Tablet 10's should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      safe if prescribed

      Dose adjustment may be needed. Sevelar 400 mg Tablet 10's should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      For children, suspensions containing the contents of Sevelar 400 mg Tablet 10's are available. The dose needs to be adjusted and recommended by a child specialist only. Sevelar 400 mg Tablet 10's is not recommended for children younger than 6 years old.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Take fresh fruits, vegetables, rice, milk, un-enriched corn and rice cereals, and soda without phosphate additives in your regular diet.
    • Avoid or limit high phosphorus addictive foods (processed meats, instant puddings, sauces, spreadable cheeses, and beverage products).
    •  Avoid intake of alcoholic beverages with Sevelar 400 mg Tablet 10's as it can make you dehydrated and may increase the side effects. 
    • Make sure you drink plenty of fluids. This will help you clear out the extra phosphate and will help you overcome some.
    • Sevelar 400 mg Tablet 10's is preferably taken with meals as it can bind to dietary phosphate and prevents its absorption into the bloodstream. Drink it with a full glass of water.
    • Do not stop taking the Sevelar 400 mg Tablet 10's dose until your doctor says so.
    • Do not use Sevelar 400 mg Tablet 10's if you have a history of bowel obstruction.

    Special Advise

    • Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is recommended while taking Sevelar 400 mg Tablet 10's.

    Other Information (SEV0057)

    This item is Not Returnable.

    Expires on or after - Sep-23

    Patients Concern

    Disease/Condition Glossary

    Hyperphosphatemia: Hyperphosphatemia (high phosphate level in blood) is often a complication of chronic kidney disease. Phosphate is an important electrolyte; it strengthens your bones, teeth, and produces energy.  When phosphate level increase in your blood due to kidney impairment (the kidney does not remove extra phosphate out of the body) can cause muscle problems and increase your risk for weak bones, heart attacks, and strokes. It is more common in people with chronic kidney disease and people on dialysis. Increased levels of serum phosphorus can also lead to hard deposits in the blood vessels (calcification). It can stiffen your blood vessels and make it harder for blood to be pumped whole the body organ. Symptoms of increased blood phosphorus include itchy skin, red eyes, bone pain, and fractures.

    FAQs

    Sevelar 400 mg Tablet 10's is in a class of medications called phosphate binders. Sevelar 400 mg Tablet 10's works by holding onto phosphate from the diet so that it can pass out of your body.

    No, ciprofloxacin may interfere with the working of Sevelar 400 mg Tablet 10's, and therefore it should not be taken at the same time as Sevelar 400 mg Tablet 10's.

    Sevelar 400 mg Tablet 10's works by holding onto phosphate from the food so that it can pass out of your body. Decreasing blood phosphate levels can help keep your bones strong, prevent unsafe buildup of minerals in your body, and possibly decrease the risk of heart disease and strokes that can result from high phosphate levels.

    Yes, constipation is the common side effect of Sevelar 400 mg Tablet 10's, though it does not occur in everyone. Please consult your doctor if the side effect becomes severe and disturb you.

    Yes, serum phosphate levels should be monitored regularly while you are taking Sevelar 400 mg Tablet 10's. The use of Sevelar 400 mg Tablet 10's may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.

    No, Sevelar 400 mg Tablet 10's is a class of medications called phosphate binder used to control the phosphate level in blood. If stop taking Sevelar 400 mg Tablet 10's, your phosphate levels may elevate again. Please consult your doctor.

    PRODUCT SUBSTITUTES

    Sevelar 400 mg Tablet 10's

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    (Inclusive of all taxes)

    Provide Delivery Location

    Strip

    1

    10 Tablet in 1 Strip