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compositionComposition:CEFEPIME-200MG+TAZOBACTAM-250MG
prescription
Prescription Medicine
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Sevepime Forte Injection is used to treat bacterial infections. It contains Cefepime and Tazobactam which work by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as pain and swelling at the injection site and skin rash. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

CEFEPIME-200MG+TAZOBACTAM-250MG

Manufacturer/Marketer :

Fountil Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Sevepime Forte Injection

Sevepime Forte Injection is a prescription intravenous (IV) antibiotic combination used to treat severe bacterial infections in different parts of the body, including the lungs, urinary tract, abdomen, skin, and bloodstream. It combines a powerful antibiotic with a medicine that helps protect the antibiotic from certain bacterial enzymes, allowing it to remain effective against difficult-to-treat bacteria, including some multidrug-resistant and beta-lactamase-producing bacteria when appropriate.

Sevepime Forte Injection is given only as an intravenous (IV) infusion by a doctor or nurse in a hospital, clinic, or other healthcare setting. Because it is administered directly into your bloodstream, food does not affect how it works. Treatment usually lasts about 7 to 14 days, depending on the type and severity of your infection, although your doctor will decide the exact duration. Receiving every scheduled dose is important to completely clear the infection and help reduce antibiotic resistance.

Most people tolerate Sevepime Forte Injection well. Some may develop mild side effects such as nausea, diarrhea, vomiting, or temporary pain and redness around the IV infusion site. These effects are usually temporary. However, contact your healthcare provider as soon as possible if you develop severe watery or bloody diarrhea, worsening skin rash, difficulty breathing, confusion, or seizures. Your medical team is experienced in managing these reactions and will provide appropriate care if needed.

Before starting treatment, tell your doctor if you have kidney disease, a history of seizures, severe bowel disease, or if you have ever had an allergic reaction to cephalosporin, penicillin, or similar antibiotics. Your doctor may adjust your dose based on your kidney function and medical condition to reduce the risk of side effects.

Some medicines, including aminoglycosides (a type of powerful antibiotic) and certain water tablets (diuretics), may increase the risk of kidney problems when used together with Sevepime Forte Injection. Although there is no proven direct interaction with alcohol, limiting or avoiding alcohol during treatment is recommended because it may worsen dehydration, stomach upset, or dizziness while your body is recovering from a serious infection. If you are pregnant, breastfeeding, an older adult, or receiving treatment for a child, your healthcare provider will carefully weigh the benefits and risks before starting therapy.

Uses of Sevepime Forte Injection

Sevepime Forte Injection is used in the treatment of various moderate to severe bacterial infections. The detailed uses of Sevepime Forte Injection are as follows:

  • Severe lung infections (pneumonia): Helps clear deep lung infections, making breathing easier.
  • Complicated urinary tract infections: Targets and eliminates bacteria in the kidneys and bladder to relieve pain and burning.
  • Abdominal infections: Treats complex infections within the stomach and intestinal area, preventing dangerous complications.
  • Skin and soft tissue infections: Clears deep-seated bacterial infections in the skin and underlying tissues, promoting healing.
  • Infections in patients with low white blood cell counts: Protects vulnerable patients with weakened immune systems by fighting off hidden bacterial threats.

Key Benefits

Sevepime Forte Injection helps treat serious bacterial infections by controlling infection quickly and supporting faster recovery. By combining a broad-spectrum antibiotic with a beta-lactamase inhibitor, it helps fight susceptible bacteria more effectively.
Benefits may include:

  • Helps treat serious bacterial infections and supports rapid control of infection.
  • Starts working soon after IV administration to help reduce fever, pain, and other infection-related symptoms.
  • Provides enhanced antibacterial activity against certain bacteria that produce beta-lactamase enzymes.
  • Suports faster recovery and helps reduce the risk of infection-related complications.
  • Helps prevent the infection from worsening or spreading when used as prescribed.
  • Completing the full course helps eliminate bacteria effectively and reduces the risk of antibiotic resistance.
     
Side effects of Sevepime Forte Injection
  • To improve liver health and aid in the removal of toxins, drink lots of water.
  • Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
  • Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
  • You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Sevepime Forte Injection will be administered by the doctor or nurse in a healthcare setting.
  • Do not self-administer.

How Sevepime Forte Injection Works

Sevepime Forte Injection contains Cefepime and Tazobactam. Cefepime: It is an antibiotic that helps treat bacterial infections by stopping the growth of bacteria and destroying them, helping the body clear the infection. Tazobactam: It helps protect Cefepime from being broken down by certain bacteria. This allows the antibiotic to work more effectively against resistant bacterial infections and improves its ability to fight a wider range of bacteria.
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Alcohol

Caution

Sevepime Forte Injection may interact with alcohol. Consult your doctor before consuming any alcohol.

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Pregnancy

Caution

Sevepime Forte Injection is a category B medicine and may not cause harmful effects to the unborn baby. However, it should be used in pregnant women only if prescribed by a doctor.

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Breast Feeding

Caution

Sevepime Forte Injection may pass into breast milk in small amounts. So, caution should be exercised when given to breastfeeding mothers.

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Driving

Safe if prescribed

Sevepime Forte Injection may not affect your ability to drive.

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Liver

Caution

Sevepime Forte Injection should be used with caution in patients with live diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Sevepime Forte Injection should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Sevepime Forte Injection is not recommended for children below two years of age. It can be used safely in children above two years. Please consult your doctor for more information.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Sevepime Forte Injection. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Sevepime Forte Injection in elderly patients. Please consult your doctor.

What if I have taken an overdose of Sevepime Forte Injection

In case of an accidental overdose, seek emergency medical care immediately or go to the nearest emergency department if an overdose is suspected. Symptoms of an overdose may include confusion, muscle twitches, or seizures.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water to help your kidneys flush Sevepime Forte Injection out of your system safely.
  • Support your gut health: Take probiotics or eat fermented foods like yogurt (spaced a few hours apart from your injection) to help restore healthy gut bacteria.
  • Eat for recovery: Consume a balanced diet rich in vitamins and proteins to support your immune system as it fights the infection.
  • Get ample rest: Allow your body's natural defenses to focus on healing by getting plenty of sleep and avoiding heavy physical strain.
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How Soon It Starts Working

The time required for Sevepime Forte Injection to start to work: Sevepime Forte Injection ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Sevepime Forte Injection last: The effect of Sevepime Forte Injection lasts for 8 to 12 hours.

What if you forget to take Sevepime Forte Injection

Since Sevepime Forte Injection is usually given in a professional medical setting, missing a dose is rare. However, if you are receiving this treatment at home and miss a scheduled dose, contact your healthcare provider immediately for instructions. Do not double the dose to make up for a missed one.

Storage

•Store the dry powder vials at room temperature, between 20°C to 25°C (68°F to 77°F) •Keep the vials in their original carton to protect them from direct light. Once mixed, use the solution immediately whenever possible.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Receive Sevepime Forte Injection only by IV infusion: Sevepime Forte Injection should be administered only by trained healthcare professionals using sterile techniques.
  • Complete the full course of treatment: Continue treatment for the entire prescribed duration, even if you feel better, to help clear the infection completely and reduce the risk of antibiotic resistance.
  • Inform your doctor about antibiotic allergies: Tell your healthcare provider if you have ever had an allergic reaction to penicillin, cephalosporins, or any other antibiotics before starting treatment.
  • Attend regular monitoring appointments: Keep all scheduled follow-up visits and blood tests so your doctor can monitor your kidney function, blood cell counts, and response to treatment.
  • Report severe diarrhea promptly: Contact your doctor immediately if you develop severe diarrhea during treatment or within several weeks after completing antibiotics. Do not treat it yourself with over-the-counter anti-diarrheal medicines unless advised by your doctor.
  • Monitor the IV site: Tell your nurse or doctor immediately if you notice increasing pain, swelling, redness, warmth, or fluid leaking around the IV infusion site.
  • Seek immediate medical attention for serious symptoms: Get emergency medical help right away if you develop difficulty breathing, swelling of the face or throat, seizures, loss of consciousness, or signs of a severe allergic reaction.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Aminoglycoside antibiotics: Taking these medicines alongside Sevepime Forte Injection may increase the risk of kidney damage. Your doctor may monitor your kidney function more closely.
  • Strong diuretics (water pills) (e.g., furosemide): Combining these with Sevepime Forte Injection may increase the risk of kidney injury.
  • Gout medicines (e.g., probenecid): These medicines may affect how some components of Sevepime Forte Injection are removed from the body. Your doctor may decide if treatment adjustments are needed.
Cefepime + TazobactamCholera vaccines
Severe
Cefepime + TazobactamCholera, live attenuated
Severe

Drug-Drug Interactions

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Cefepime + TazobactamCholera vaccines
Severe
How does the drug interact with Sevepime Forte Injection:
Taking the cholera vaccine after or along with cefepime may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Cefepime and Cholera vaccines together can evidently cause an interaction, it can be taken if your doctor has suggested it. Make sure to inform the doctor if you are on Cholera vaccine dose or you have already taken it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
Cefepime + TazobactamCholera, live attenuated
Severe
How does the drug interact with Sevepime Forte Injection:
Taking the cholera vaccine after or along with cefepime may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Cefepime and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. Make sure to inform the doctor if you are on Cholera vaccine dose or you have already taken it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
Cefepime + TazobactamMycophenolic acid
Severe
How does the drug interact with Sevepime Forte Injection:
Taking mycophenolic acid and cefepime together can reduce the blood levels and effects of mycophenolic acid.

How to manage the interaction:
Using mycophenolic acid and cefepime together can lead to an interaction; it can be taken if your doctor has suggested it. If you experience any symptoms, like less urine output, shortness of breath, or swelling, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No significant food interactions are known because Sevepime Forte Injection is given directly into a vein, so food does not affect how it works.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTIC COMBINATION]

FAQs

Sevepime Forte Injection is used to treat bacterial infections.
Sevepime Forte Injection contains Cefepime and Tazobactam. Cefepime reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival. Tazobactam inhibits the action of beta-lactamase, an enzyme produced by the bacteria to destroy antibiotics (cefepime).
The common side-effects of Sevepime Forte Injection are pain and swelling at the injection site, diarrhea, nausea, vomiting, headache and skin rash. These side-effects are usually mild and temporary. However, inform your doctor immediately if any of these side-effects persist or get worse.
In individuals who have kidney problems, colitis (inflammation of the intestine), and diabetes, Sevepime Forte Injection should be used with caution as this medicine may worsen the condition.
People allergic to penicillin should not take Sevepime Forte Injection as they may develop cross-sensitivity (sensitivity to drugs with similar structures). Sevepime Forte Injection contains cefepime, which has a similar structure to that of penicillin.
Sevepime Forte Injection is given only as an intravenous (IV) infusion into a vein by a doctor, nurse, or another trained healthcare professional. It is usually administered in a hospital, clinic, or supervised home infusion setting. The exact dose and duration depend on the type and severity of your infection.
Treatment commonly lasts 7 to 14 days, although some infections may require a shorter or longer course. Your doctor will decide the appropriate duration based on your infection, your response to treatment, and laboratory test results.
No. Sevepime Forte Injection only works against bacterial infections. It does not treat viral illnesses such as the common cold, influenza (flu), or most sore throats caused by viruses. Using antibiotics when they are not needed can contribute to antibiotic resistance.
There is no known direct interaction between alcohol and Sevepime Forte Injection. However, because your body is recovering from a serious infection, limiting or avoiding alcohol is recommended as it may worsen dehydration, stomach upset, or dizziness.
Even if you start feeling better after a few days, some bacteria may still remain in your body. Completing the full prescribed course helps eliminate the infection completely and reduces the risk of antibiotic resistance and recurrence of the infection.
Most people tolerate Sevepime Forte Injection well. However, people with existing kidney disease or those taking certain medicines may require closer monitoring. Your doctor may perform blood tests during treatment and adjust your dose if necessary.
Mild diarrhea can occur with antibiotics. However, if you develop severe, persistent, watery, or bloody diarrhea, especially with stomach cramps or fever, contact your doctor immediately. Do not start anti-diarrheal medicines or stop your antibiotic on your own unless your healthcare provider advises you to do so.
Sevepime Forte Injection should only be used during pregnancy or breastfeeding if your doctor believes the expected benefits outweigh the possible risks. Always tell your healthcare provider if you are pregnant, planning pregnancy, or breastfeeding before starting treatment.
Yes. Sevepime Forte Injection may be prescribed for children when appropriate. The dose is carefully calculated according to the child's body weight, age, kidney function, and type of infection. It should always be given under the supervision of a pediatric specialist or qualified healthcare professional.
A seizure or severe allergic reaction is a medical emergency. Call emergency medical services or go to the nearest emergency department immediately. Inform the healthcare team that you are receiving Sevepime Forte Injection so they can provide appropriate treatment as quickly as possible.

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Country of origin

INDIA

Manufacturer/Marketer address

118-120, Mastermind 4,Near Hotel Royal Palms,Aarey Colony,Goregaon(E) Mumbai- 400 065
Other Info - SEV0055
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