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Signoflam-TH 4 Tablet is used to relieve pain and inflammation associated with musculoskeletal and joint disorders. It works by relieving muscle stiffness and blocking chemical messengers that cause pain and inflammation. In some cases, this medicine may cause side effects such as nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ACECLOFENAC-100MG+PARACETAMOL-325MG+THIOCOLCHICOSIDE-4MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Signoflam-TH 4 Tablet

Signoflam-TH 4 Tablet is a prescription medication used to treat painful muscle spasms associated with various acute muscle and joint conditions. It helps reduce severe pain, muscle stiffness, and swelling, allowing for improved movement and comfort. This medicine is commonly prescribed for acute musculoskeletal conditions like low back pain, muscle strains, or joint sprains.

To get the best results, you should take Signoflam-TH 4 Tablet consistently at the exact times your doctor prescribes, rather than only when you feel pain. It is highly recommended to take this medication with food or immediately after a meal to help protect your stomach from irritation. Complementing this treatment with gentle stretching, adequate hydration, and sufficient rest can significantly speed up your recovery.

While taking Signoflam-TH 4 Tablet , some people may experience mild side effects like nausea, diarrhoea, drowsiness, or a mild upset stomach. However, if you notice serious signs such as severe abdominal pain, yellowing of your skin or eyes (which points to liver damage), dark urine, or an allergic reaction like a skin rash or swelling, you must stop taking the medicine and consult your doctor immediately.

Before starting Signoflam-TH 4 Tablet , talk to your doctor if you have a history of stomach ulcers, kidney problems, heart issues, or asthma. Do not take this if you have active stomach bleeding, severe liver or kidney failure, or if you have previously had a severe allergic reaction to pain relievers. It is also not suitable for individuals with certain rare genetic muscle disorders.

This medicine can interact with other pain relievers, blood thinners, and blood pressure medications, so it is important to share your full medication list with your pharmacist. Avoid drinking alcohol while on this medication, as it increases your risk of stomach bleeding and liver damage. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before taking Signoflam-TH 4 Tablet to ensure it is safe for you.

Aceclofenac belongs to the non-steroidal anti-inflammatory drug (NSAID) class. Like other NSAIDs, prolonged or high-dose use may increase the risk of serious cardiovascular events, such as heart attack or stroke, particularly in people with existing heart disease or cardiovascular risk factors. This medicine is therefore intended for the shortest duration necessary to control symptoms.

Uses of Signoflam-TH 4 Tablet

Your doctor may prescribe this medicine to treat several conditions, including:

  • Painful muscle spasms: Signoflam-TH 4 Tablet helps by relaxing stiff muscles and reducing the pain associated with sudden, involuntary muscle contractions.
  • Lower back pain: It targets both the muscle tightness and the underlying inflammation to restore physical comfort and mobility.
  • Joint pain and swelling: It reduces inflammation and pain in the joints caused by strains, sprains, or flare-ups of chronic joint issues.
  • Post-operative recovery: It aids in easing acute pain and muscle tension following orthopaedic surgeries or physical trauma.

Key Benefits

Taking Signoflam-TH 4 Tablet helps you return to your daily routine by targeting pain and muscle stiffness at the same time. By relaxing tight muscle fibres and lowering inflammation, it breaks the cycle of pain and muscle spasm that often keeps you immobilised.

Key benefits include: 

  • Faster recovery times: By easing both pain and muscle stiffness, it allows you to participate in physical therapy and recovery exercises sooner.
  • Improved physical mobility: The medicine helps restore your range of motion, making basic movements like bending, walking, and sitting much more comfortable.
  • Dual-action relief: It simultaneously calms hyperactive muscles and blocks pain signals, providing comprehensive comfort compared to taking single-ingredient pain relievers.
Side effects of Signoflam-TH 4 Tablet
  • Do not consume spicy foods, caffeine, and alcohol.
  • Choose low-acid fruits and vegetables like apples, melons, and carrots.
  • Include whole grains like whole-wheat bread, oatmeal, and brown rice.
  • Limit processed meats like hotdogs and sausages.
  • Avoid fatty, spicy, or acidic salad dressings.
  • Limit tomatoes and tomato-based products.
  • Quit smoking to promote ulcer healing.
  • Adopt a balanced diet and lifestyle to reduce the risk of peptic ulcers.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • It is advised to take Signoflam-TH 4 Tablet with food to avoid any stomach upset or as advised by a doctor.
  • Adhere to your doctor’s guidance regarding the dosage and timing of this medication for optimal effectiveness.
  • Swallow Signoflam-TH 4 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Signoflam-TH 4 Tablet Works

To help you understand how Signoflam-TH 4 Tablet works, it is helpful to look at its three active components, each of which relieves pain and muscle spasm through a different mechanism. First, thiocolchicoside is a muscle relaxant that acts mainly on inhibitory receptors within the spinal cord, including glycine and GABA-A receptor pathways. By reducing abnormal muscle activity and muscle spasms, it helps improve movement and relieve pain. Because thiocolchicoside has been associated with a potential risk of genotoxicity, it is approved only for short-term use and should be taken exactly as prescribed by your doctor. Second, aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces the production of prostaglandins, chemical messengers responsible for pain, inflammation, and swelling at the site of injury. Third, paracetamol helps relieve pain and reduce fever. Although its exact mechanism is not fully understood, it is thought to act within both the brain and spinal cord to reduce pain perception and regulate body temperature. By combining these complementary actions, Signoflam-TH 4 Tablet provides effective short-term relief of painful muscle spasms, inflammation, and associated pain.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Signoflam-TH 4 Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe Signoflam-TH 4 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Signoflam-TH 4 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Signoflam-TH 4 Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Signoflam-TH 4 Tablet should not be given to children as safety and effectiveness were not established.

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Heart

Unsafe

Signoflam-TH 4 Tablet is contraindicated in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

Signoflam-TH 4 Tablet can be given in elderly patients with extreme caution, due to the increased risk of dizziness, drowsiness, or sudden falls, liver/kidney functions.

What if I have taken an overdose of Signoflam-TH 4 Tablet

In case of an accidental overdose, seek immediate emergency medical attention or contact a poison control centre. Symptoms of an overdose may include severe drowsiness, vomiting, severe stomach pain, shallow breathing, or loss of consciousness.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day. Well-hydrated muscles are less prone to painful spasms and recover faster.
  • Eat stomach-friendly foods: Since this medication can sometimes cause mild stomach irritation, pair your meals with fibre-rich foods, and avoid highly spicy or acidic meals while on this treatment.
  • Apply gentle heat or cold packs: Using a warm compress can help relax tight muscles, while an ice pack can reduce acute swelling. Use these for 15–20 minutes at a time.
  • Engage in low-impact movement: Avoid complete bed rest. Gentle movements like short walks or light stretching help maintain blood flow to the affected muscles, promoting faster healing.
  • Incorporate anti-inflammatory foods: Focus on a diet rich in antioxidants, such as leafy greens, berries, and omega-3 fatty acids (found in fish or flaxseeds), to support your body's natural healing process.
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How Soon It Starts Working

The time required for Signoflam-TH 4 Tablet to start to work: Signoflam-TH 4 Tablet ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Signoflam-TH 4 Tablet last: The effect of Signoflam-TH 4 Tablet lasts for 6 to 8 hours.

What if you forget to take Signoflam-TH 4 Tablet

If you miss a dose of Signoflam-TH 4 Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Signoflam-TH 4 Tablet at room temperature, ideally between 20°C and 25°C (68°F and 77°F), in a dry place away from moisture, heat, and direct sunlight.

Drug Warnings

  • Check the packaging: Always inspect the blister pack before use; do not take the tablet if the foil is broken, punctured, or shows signs of tampering.
  • Avoid driving or operating machinery: Signoflam-TH 4 Tablet can cause drowsiness and dizziness. Avoid tasks that require sharp mental focus until you know how this medication affects you.
  • Avoid other paracetamol-containing products: Taking other over-the-counter pain or cold remedies at the same time can lead to an accidental paracetamol overdose, increasing the risk of liver damage.
  • Watch for signs of bleeding: If you notice unusual bruising, nosebleeds, or blood in your stool, contact your doctor immediately.
  • Limit the duration of use: Use Signoflam-TH 4 Tablet only for the short duration prescribed by your doctor to protect your kidneys, liver, and digestive tract from long-term side effects.
  • Use this medicine only for the prescribed short treatment duration. Thiocolchicoside is recommended only for short-term use because prolonged use may increase the risk of serious adverse effects. Likewise, prolonged use of aceclofenac, an NSAID, may increase the risk of heart attack or stroke, particularly in people with existing cardiovascular disease or risk factors. 

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Other pain relievers (NSAIDs): Taking this with other NSAIDs may increase the risk of severe stomach ulcers and digestive tract bleeding.
  • Blood thinners (like warfarin): Combining these can significantly raise the risk of internal bleeding.
  • Blood pressure medicines (like ACE inhibitors or diuretics): Signoflam-TH 4 Tablet may reduce the effectiveness of these medications and increase the risk of kidney strain.
  • Central nervous system depressants: Taking this alongside other muscle relaxants, sleeping pills, or anxiety medications can cause extreme drowsiness and slowed breathing.
Aceclofenac + Paracetamol + serratiopeptidaseEthanol
Severe
Aceclofenac + Paracetamol + serratiopeptidaseMipomersen
Severe

Drug-Drug Interactions

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Aceclofenac + Paracetamol + serratiopeptidaseEthanol
Severe
How does the drug interact with Signoflam-TH 4 Tablet:
Taking Signoflam-TH 4 Tablet with Ethanol can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Signoflam-TH 4 Tablet with Ethanol can lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + Paracetamol + serratiopeptidaseMipomersen
Severe
How does the drug interact with Signoflam-TH 4 Tablet:
Co-administration of Mipomersen with Signoflam-TH 4 Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Signoflam-TH 4 Tablet and Mipomersen, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + Paracetamol + serratiopeptidaseAtenolol
Severe
How does the drug interact with Signoflam-TH 4 Tablet:
Co-administration of Atenolol with Signoflam-TH 4 Tablet could decrease the action of Atenolol.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Signoflam-TH 4 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
Aceclofenac + Paracetamol + serratiopeptidaseTeriflunomide
Severe
How does the drug interact with Signoflam-TH 4 Tablet:
Co-administration of Teriflunomide with Signoflam-TH 4 Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Signoflam-TH 4 Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + Paracetamol + serratiopeptidaseKetoconazole
Severe
How does the drug interact with Signoflam-TH 4 Tablet:
Co-administration of Signoflam-TH 4 Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Signoflam-TH 4 Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, stomach pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + Paracetamol + serratiopeptidaseLeflunomide
Severe
How does the drug interact with Signoflam-TH 4 Tablet:
Co-administration of Signoflam-TH 4 Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Signoflam-TH 4 Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + Paracetamol + serratiopeptidaseLomitapide
Severe
How does the drug interact with Signoflam-TH 4 Tablet:
Co-administration of Lomitapide and Signoflam-TH 4 Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Signoflam-TH 4 Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Consuming alcohol while taking this medicine significantly increases the risk of liver damage and stomach bleeding.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Signoflam-TH 4 Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, bone and joint pain.
Signoflam-TH 4 Tablet contains Thiocolchicoside, Aceclofenac, and Paracetamol. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac and Paracetamol work by blocking the chemical messengers that cause pain and inflammation at the injured or damaged site.
Signoflam-TH 4 Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is tenderness and swelling in the joints.
Diarrhoea might be a side-effect of Signoflam-TH 4 Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
Signoflam-TH 4 Tablet should not be taken for longer durations unless prescribed by the doctor. If Signoflam-TH 4 Tablet has been prescribed for longer durations, regular monitoring of kidney function, liver function, and blood count is advised, particularly in elderly patients.
Signoflam-TH 4 Tablet may cause abnormal chromosome numbers in the sperm cells, which might damage sperm. This might cause problems with male fertility. Consult your doctor before taking Signoflam-TH 4 Tablet if you plan to become a father.
Dry mouth could be a side-effect of Signoflam-TH 4 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of mouth.
Do not take Signoflam-TH 4 Tablet with other painkillers, such as aspirin, ibuprofen, naproxen, celecoxib, or etoricoxib, unless your doctor advises it. Combining Signoflam-TH 4 Tablet with other painkillers can increase the risk of serious side effects, including stomach irritation, liver damage, or kidney problems, and may also interact with other medications.
Signoflam-TH 4 Tablet is not an antibiotic. It is a combination medication containing Aceclofenac (a non-steroidal anti-inflammatory drug), Paracetamol (a pain and fever reliever), and Thiocolchicoside (a muscle relaxant). None of these ingredients have antibacterial properties.
The common side effects of Signoflam-TH 4 Tablet include nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhoea. Most of these side effects of Signoflam-TH 4 Tablet do not require medical attention and will resolve gradually over time. However, if the side effects persist, please consult your doctor.
Although Signoflam-TH 4 Tablet contains pain-relieving ingredients Thiocolchicoside, Aceclofenac, and Paracetamol, this specific combination is not designed to treat period pain. If you're experiencing menstrual cramps or discomfort, consult your healthcare provider for proper diagnosis and treatment. They will help identify the underlying cause of your pain and recommend appropriate treatment options to address it. Don't rely solely on painkillers; seek medical attention to receive personalized care and find relief from your period pain.
No, do not take Signoflam-TH 4 Tablet for toothache pain unless your doctor or dentist has specifically advised you to do so. Toothaches can be a symptom of various underlying conditions, and Signoflam-TH 4 Tablet may not address the root cause of your pain. Additionally, using Signoflam-TH 4 Tablet without a proper diagnosis and guidance from a healthcare professional may lead to delayed or inadequate treatment, potentially causing more severe problems. Always consult your doctor or dentist to determine the best course of treatment for your specific needs.
Signoflam-TH 4 Tablet is a painkiller medication that combines three active ingredients: Aceclofenac, an anti-inflammatory, Paracetamol, a pain reliever, and Thiocolchicoside, a muscle relaxant.
When your pain subsides, you can discontinue taking Signoflam-TH 4 Tablet . However, it's crucial to adhere to the treatment duration recommended by your doctor to ensure the medication's effectiveness. Abruptly stopping Signoflam-TH 4 Tablet may compromise its pain-relieving and anti-inflammatory benefits.
Signoflam-TH 4 Tablet is contraindicated in patients who are allergic to any of its components. Do not take Signoflam-TH 4 Tablet if you have severe heart problems, stomach ulcers or perforations, bleeding problems (such as bleeding from the stomach, intestine, or brain), a history of bypass surgery, heart attack, blood circulation issues, or inflammation of the intestines.
It is generally safe to take Signoflam-TH 4 Tablet with a vitamin B-complex supplement, as there are no significant known interactions between them. However, please consult your doctor before taking any supplements to ensure they are safe based on your health condition.
The use of Signoflam-TH 4 Tablet may cause kidney damage if taken in high doses or for a long time. Normally, the kidneys produce prostaglandins, a chemical that helps protect them from damage. Prolonged use of Signoflam-TH 4 Tablet (painkillers) reduces the levels of prostaglandins, increasing the risk of kidney damage. If you have a history of kidney problems, please consult your doctor, as they may need to adjust your dosage.
Taking a higher dose of Signoflam-TH 4 Tablet may increase the risk of side effects without significantly improving its effectiveness. It may lead to adverse effects such as liver damage (from Paracetamol) or gastrointestinal problems (from Aceclofenac). Please follow the recommended dosage and consult your doctor before making any changes.
The use of Signoflam-TH 4 Tablet can cause liver damage if taken in high doses or for a long time. Its ingredients, particularly Paracetamol and Aceclofenac, are known to be harmful to the liver when overused. If you have a history of liver problems, please consult your doctor, as they may need to adjust your dosage.
Signoflam-TH 4 Tablet should be stored in a cool and dry place, away from direct sunlight. Keep it out of reach of children.
It is highly recommended to take Signoflam-TH 4 Tablet with food or immediately after a meal. Taking it on an empty stomach can increase the risk of stomach irritation, nausea, or indigestion. Talk to your doctor or pharmacist if you experience persistent stomach discomfort.
Yes, Signoflam-TH 4 Tablet contains a muscle relaxant component that can cause drowsiness, dizziness, or lightheadedness in some people. Avoid driving, operating heavy machinery, or performing tasks that require full mental alertness until you know how this medicine affects you.
No, you should avoid alcohol while taking Signoflam-TH 4 Tablet . Alcohol combined with this medication increases the risk of severe liver damage and stomach bleeding. Talk to your doctor if you have concerns about alcohol use.
You should not take other pain relievers, cold medicines, or fever reducers containing paracetamol or NSAIDs while taking Signoflam-TH 4 Tablet . Doing so can lead to an accidental overdose, risking severe liver damage or stomach ulcers. Always check with your pharmacist before combining medications.
Signoflam-TH 4 Tablet is generally not recommended for use during pregnancy or breastfeeding unless specifically deemed essential by your healthcare provider. Some components may pose risks to the developing baby or pass into breast milk. Talk to your doctor to discuss safer alternatives.
Take the missed dose as soon as you remember. If your next scheduled dose is only a few hours away, skip the missed dose entirely and resume your normal schedule. Never take two doses at the same time to make up for a missed one.
Signoflam-TH 4 Tablet is typically prescribed for short-term relief of acute, painful muscle spasms. Long-term use is generally not recommended due to the increased risk of stomach, liver, and kidney side effects. If your pain persists, talk to your doctor to evaluate other long-term management strategies.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - SIG0079

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