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  3. Sitazit-Trio 1000 mg Tablet 10's

Sitazit-Trio 1000 mg Tablet 10's, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Sitazit-Trio 1000 mg Tablet 10's is used to manage blood sugar levels in people with type 2 diabetes. It works by increasing the body’s response to insulin and decreasing the amount of glucose made by the liver and absorbed from food. In some cases, this medicine may cause side effects like headache, nausea, stomach upset and diarrhoea. Inform the doctor if you are taking any other medication or have any pre-existing medical conditions.

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Synonym :

METFORMIN HYDROCHLORIDE+PIOGLITAZONE HYDROCHLORIDE+SITAGLIPTIN

Composition :

METFORMIN-1000MG + PIOGLITAZONE-15MG + SITAGLIPTIN-100MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sitazit-Trio 1000 mg Tablet 10's

Sitazit-Trio 1000 mg Tablet 10's belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus. This condition causes blood sugar to be too high because the body does not normally produce or use insulin.

Sitazit-Trio 1000 mg Tablet 10's contains Metformin, Pioglitazone, and Sitagliptin. These drugs work by increasing the body’s response to insulin and decreasing the amount of glucose made by the liver and absorbed from food. Thus, it helps control blood sugar levels.

 In some cases, Sitazit-Trio 1000 mg Tablet 10's may cause side effects such as nausea, stomach upset, diarrhoea, and headache. Most of these side effects may not require medical attention and resolve gradually over time. However, if any side effects persist or worsen, consult the doctor.
 
Do not take Sitazit-Trio 1000 mg Tablet 10's if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.

Uses of Sitazit-Trio 1000 mg Tablet 10's

Sitazit-Trio 1000 mg Tablet 10's is use din the treatment of type-2 diabetes mellitus. The detailed use of Sitazit-Trio 1000 mg Tablet 10's is as follows:<br/>• Sitazit-Trio 1000 mg Tablet 10's is used to manage type 2 diabetes mellitus by improving blood sugar control.<br/>

Directions for Use

  • Sitazit-Trio 1000 mg Tablet 10's should be taken after meals to avoid stomach upset.
  • Follow your doctor's instructions on the dosage and timing of Sitazit-Trio 1000 mg Tablet 10's. Take this medication preferably at the same time each day to ensure consistency and effectiveness.
  • Swallow Sitazit-Trio 1000 mg Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Sitazit-Trio 1000 mg Tablet 10's is used to treat type-2 diabetes mellitus. It contains Metformin (biguanides), Pioglitazone (thiazolidinediones) and Sitagliptin (dipeptidyl peptidase-4 (DPP-4) inhibitors). Metformin increases the body’s response to insulin and decreases the amount of glucose absorbed from food and made by the liver. Pioglitazone enhances the body’s sensitivity to insulin. Sitagliptin increases certain natural substances in the body that lower blood glucose levels. Together, Sitazit-Trio 1000 mg Tablet 10's helps treat type 2 diabetes and prevents complications of diabetes such as kidney damage and nerve and eye problems.

How Sitazit-Trio 1000 mg Tablet 10's Works

Sitazit-Trio 1000 mg Tablet 10's contains Metformin, Pioglitazone, and Sitagliptin. These drugs work by increasing the body’s response to insulin and decreasing the amount of glucose made by the liver and absorbed from food. Thus, it helps control blood sugar levels.

Storage

• Store in a cool and dry place away from sunlight.• Keep Sitazit-Trio 1000 mg Tablet 10's out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Sitazit-Trio 1000 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Sitazit-Trio 1000 mg Tablet 10's

If you take too much Sitazit-Trio 1000 mg Tablet 10's, you may experience low blood sugar. If you think that you’ve taken too much of this medication or have symptoms of low blood sugar, get medical help right away.

Drug Warnings

Do not take Sitazit-Trio 1000 mg Tablet 10's if you are allergic to any of its components. Inform the doctor if you have type 1 diabetes, kidney or liver problems, diabetic ketoacidosis, heart problems, pancreatitis (inflammation of the pancreas), high triglycerides, gallstones, alcoholism, bladder cancer, eye problems caused by diabetes, bone problems, or if you use insulin. Consult the doctor if you are pregnant or breast-feeding. Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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SitagliptinGatifloxacin
Critical
MetforminIobitridol
Critical

Drug-Drug Interactions

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SitagliptinGatifloxacin
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Sitazit-Trio 1000 mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Gatifloxacin is not recommended as it can lead to a possible interaction, However, it can be taken if advised by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without a doctor's advice.
MetforminIobitridol
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Sitazit-Trio 1000 mg Tablet and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Iomeprol with Sitazit-Trio 1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopamidol
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Iopamidol with Sitazit-Trio 1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoglicic acid
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Ioglicic acid with Sitazit-Trio 1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Iopentol with Sitazit-Trio 1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIofendylate
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Iofendylate with Sitazit-Trio 1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Iotroxic acid with Sitazit-Trio 1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Iopydol with Sitazit-Trio 1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIoxitalamic acid
Critical
How does the drug interact with Sitazit-Trio 1000 mg Tablet:
Co-administration of Sitazit-Trio 1000 mg Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Sitazit-Trio 1000 mg Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fruits, vegetables, whole grains, and beans in your diet.
  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
  • Maintain a healthy weight by exercising regularly.
  • Rest properly.
  • Avoid stress by doing meditation or yoga.
  • Limit saturated and processed food.
  • Stay physically active as it helps manage blood glucose levels. 
  • Avoid/limit the consumption of alcohol as it may affect blood sugar levels.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Sitazit-Trio 1000 mg Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid/limit alcohol consumption as it might affect blood sugar levels.

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Pregnancy

Consult your doctor

Please consult the doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Sitazit-Trio 1000 mg Tablet 10's if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult your doctor if you are breastfeeding. Your doctor will decide whether Sitazit-Trio 1000 mg Tablet 10's can be taken during lactation.

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Driving

Consult your doctor

It is not known if Sitazit-Trio 1000 mg Tablet 10's affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult the doctor if you have kidney problems or any concerns regarding this.

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Children

Consult your doctor

Limited information is available. Please consult the doctor if you have any concerns regarding the usage of Sitazit-Trio 1000 mg Tablet 10's in children.

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Heart

If you have heart problems, it's essential to approach the Sitazit-Trio 1000 mg Tablet 10's with caution and under medical supervision.

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Geriatrics

Caution

Sitazit-Trio 1000 mg Tablet 10's are generally safe for geriatric use, while Pioglitazone requires caution due to risks like fluid retention and heart failure. It should only be taken under medical supervision with regular monitoring.

Have a query?

FAQs

Sitazit-Trio 1000 mg Tablet 10's is used to treat type 2 diabetes mellitus. It helps manage blood sugar/glucose levels.

Sitazit-Trio 1000 mg Tablet 10's works by increasing the amount of insulin made by the body. Additionally, it also decreases the amount of glucose made by the liver and absorbed from food. Thereby, it helps lower blood glucose levels.

Do not stop taking Sitazit-Trio 1000 mg Tablet 10's without consulting your doctor, as it may cause an increase in blood glucose levels. Continue taking Sitazit-Trio 1000 mg Tablet 10's for as long as your doctor has prescribed it to you. Speak with your doctor if you experience any difficulty while taking Sitazit-Trio 1000 mg Tablet 10's.

Sitazit-Trio 1000 mg Tablet 10's may cause hypoglycaemia (low blood sugar) in some cases. Symptoms of low blood sugar are headache, dizziness, sweating, hunger, irritability, confusion, and fast heartbeat. If you experience these symptoms, eat or drink a fast-acting source of sugar such as candy, fruit juice, raisins or crackers.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai 400 026.
Other Info - SIT0739

Disclaimer

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 8, 2025 | 10:56 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/metformin.html
  2. https://www.drugs.com/mtm/sitagliptin.html
  3. https://www.drugs.com/mtm/pioglitazone.html

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