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  3. Solonex Tablet 10's

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Solonex Tablet 10's, Pack of 10 TABLETS
Solonex Tablet 10's, Pack of 10 TABLETS
Solonex Tablet 10's, Pack of 10 TABLETS
Solonex Tablet 10's, Pack of 10 TABLETS
Solonex Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Solonex Tablet is used to treat and prevent tuberculosis (TB). It contains isoniazid, which prevents bacteria from producing mycolic acid, an enzyme required for cell wall formation (protective coating). Thus, kills bacteria and inhibits the spread of infection. It may cause side effects such as fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, numbness, or tingling in the feet or hands. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ISONIAZID-300MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Solonex Tablet

Solonex Tablet belongs to a group of medicines called anti-tubercular agents, which are primarily used to treat and prevent tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other parts of the body, including the kidneys, brain, spine, and bone marrow. Solonex Tablet does not work against infections caused by the virus.

Solonex Tablet contains isoniazid, an antibiotic that prevents bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, Solonex Tablet inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

Take Solonex Tablet for as long as your doctor has prescribed it based on your medical condition. Sometimes, you may experience fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, numbness, or tingling in the feet or hands as side effects of Solonex Tablet . Most of these side effects do not require medical attention and typically resolve on their own over time. However, if any of these side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Solonex Tablet or any other medicines. If you are pregnant or breastfeeding, please inform your doctor before taking Solonex Tablet . Solonex Tablet may cause mental health problems, fits, or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking Solonex Tablet . Avoid foods and drinks containing histamine or tyramine, such as cured meats, matured cheeses, soy, tuna, salmon, mackerel, wine, and beer, while taking Solonex Tablet , as they may interact with this medication. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems, or have suffered from psychosis (mental disturbances), inform your doctor before taking Solonex Tablet .

Uses of Solonex Tablet

Solonex Tablet is used in the treatment of Tuberculosis. The detailed uses of Solonex Tablet are as follows:<br/>• Tuberculosis (TB): Solonex Tablet is a first-line medication for treating tuberculosis by killing the Mycobacterium tuberculosis bacteria that cause the infection.<br/>• Latent TB Infection: Solonex Tablet prevents active TB in individuals with latent infection, especially those with high-risk factors like active TB patients, positive tuberculin skin test, HIV infection, and pulmonary fibrosis.<br/>

Directions for Use

  • Solonex Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.
  • Your doctor will determine the dosage and timing of this medication based on your body weight and medical condition.
  • Swallow Solonex Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Solonex Tablet contains isoniazid, an antibiotic used to treat and prevent tuberculosis. Solonex Tablet prevents bacteria from producing mycolic acids, which are essential for forming cell walls (a protective coating). Additionally, Solonex Tablet may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that cause tuberculosis (TB) and eliminates the infection.

How Solonex Tablet Works

Solonex Tablet contains isoniazid, an antibiotic that prevents bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, Solonex Tablet inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

Storage

Keep Solonex Tablet out of reach and sight of children.
Side effects of Solonex Tablet
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Solonex Tablet

Do not take more than the prescribed dose of Solonex Tablet as it may cause an overdose. The symptoms of overdose include dizziness, nausea, vertigo, fits and acidosis (upset of acid balance in the body). If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Solonex Tablet , please inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Solonex Tablet . Solonex Tablet may cause mental health problems, fits, or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking Solonex Tablet . Avoid foods and drinks containing a high level of tyramine, such as fermented foods, cheese, cured meat, soya, tuna, salmon, mackerel, wine, and beer, while taking Solonex Tablet as they might cause drug-food interaction. Avoid alcohol consumption with Solonex Tablet as it may cause liver damage. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems, or have suffered from psychosis (mental disturbances), inform your doctor before taking Solonex Tablet .

Drug-Drug Interactions

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IsoniazidLovastatin
Critical
IsoniazidLomitapide
Critical

Drug-Drug Interactions

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IsoniazidLovastatin
Critical
How does the drug interact with Solonex Tablet:
When Lovastatin is taken with Solonex Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Solonex Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with Solonex Tablet:
When Lomitapide is taken with Solonex Tablet, Solonex Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Solonex Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidRegorafenib
Critical
How does the drug interact with Solonex Tablet:
When Solonex Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Solonex Tablet is not recommended, it taken can be taken if prescribed by the doctor.
IsoniazidTizanidine
Severe
How does the drug interact with Solonex Tablet:
Co-administration of Solonex Tablet may considerably enhance the blood levels of Tizanidine, which may result in side effects.

How to manage the interaction:
There may be a possibility of interaction between Tizanidine and Solonex Tablet, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience excessive drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm. Do not stop taking any medications without consulting a doctor.
IsoniazidHalothane
Severe
How does the drug interact with Solonex Tablet:
When Halothane is taken with Solonex Tablet, can increase the side affects of liver.

How to manage the interaction:
Co-administration of Solonex Tablet with Halothane can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, appetite loss, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor right away. Do not stop using any medications without talking to a doctor.
IsoniazidBCG vaccine
Severe
How does the drug interact with Solonex Tablet:
When BCG vaccine is used with Solonex Tablet, its effectiveness may be reduced.

How to manage the interaction:
Although there is a possible interaction between Solonex Tablet and BCG vaccine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
IsoniazidHalofantrine
Severe
How does the drug interact with Solonex Tablet:
Co-administration of Solonex Tablet and Halofantrine together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Solonex Tablet and Halofantrine together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IsoniazidMipomersen
Severe
How does the drug interact with Solonex Tablet:
Taking Solonex Tablet and Mipomersen can increase the risk and severity of side effects of liver.

How to manage the interaction:
Although taking Solonex Tablet and Mipomersen together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms -fatigue, decreased hunger, nausea, vomiting, abdominal discomfort, dark urine, pale feces, yellowing of the skin or eyes, joint pain or swelling, fever, chills, unusual bleeding or bruises, skin rash, itching, and/or skin itchiness, please contact a doctor right away. Do not stop using any medications without talking to a doctor.
IsoniazidGlimepiride
Severe
How does the drug interact with Solonex Tablet:
Co-administration of Glimepiride with Solonex Tablet may interfere with blood glucose control and reduce the effectiveness of Glimepiride.

How to manage the interaction:
Although there is a possible interaction, Glimepiride can be taken with Solonex Tablet if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
IsoniazidAlfentanil
Severe
How does the drug interact with Solonex Tablet:
Co-administration of Solonex Tablet will enhance the amount or action of Alfentanil when taken together.

How to manage the interaction:
Taking Alfentanil with Solonex Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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ISONIAZID-300MGCaffeine containing foods/drinks

Drug-Food Interactions

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ISONIAZID-300MGCaffeine containing foods/drinks
Common Foods to Avoid:
Dark Chocolate, Cocoa, Coffee, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking caffeine containing products including chocolates(which contains caffeine) during Solonex Tablet treatment may lead to an interaction. Avoid caffiene and its products during treatment with Solonex Tablet.

Diet & Lifestyle Advise

  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help improve the immune system.
  • Pineapple juice may help soothe the symptoms due to its anti-inflammatory properties.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help relieve a cough.
  • Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS

Solonex Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Solonex Tablet as it may increase the risk of liver damage. Please consult your doctor if you have any concerns.

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Pregnancy

Safe if prescribed

If you are pregnant, consult your doctor before taking Solonex Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Safe if prescribed

Solonex Tablet is excreted in breast milk in low quantities. If you are breastfeeding, consult your doctor before taking Solonex Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Driving

Unsafe

Solonex Tablet may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking Solonex Tablet .

bannner image

Liver

Consult your doctor

Take Solonex Tablet with caution, especially if you have a history of liver disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Consult your doctor

Take Solonex Tablet with caution, especially if you have a history of kidney disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Caution

Solonex Tablet is not recommended for children below 3 months of age. However, in children above 3 months, Solonex Tablet should be used under medical supervision.

Have a query?

FAQs

Solonex Tablet is used to treat and prevent tuberculosis (TB).

Solonex Tablet contains isoniazid, an antibiotic used to treat and prevent tuberculosis. Solonex Tablet prevents bacteria from producing mycolic acids, which are required to form cell walls (protective coating). Additionally, Solonex Tablet may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die due to the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that cause tuberculosis (TB) and eliminates the infection.

It is not recommended to take Solonex Tablet with food. You are advised to take Solonex Tablet on an empty stomach at least 1 hour before a meal or 2 hours after a meal for better absorption.

You are recommended to avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer as they may interact with Solonex Tablet and cause adverse effects such as sweating, headache, dizziness, light-headedness, flushing (reddening of the skin), fainting due to low blood pressure, uneven, fast or forceful heartbeat.

Yes, Solonex Tablet may cause liver problems in some patients. However, please consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may monitor your liver function while on treatment with Solonex Tablet .

You are advised to consult a doctor before taking phenytoin with Solonex Tablet , as taking these medicines together may increase the levels of phenytoin in the blood and cause toxic effects. However, if you experience dizziness, vomiting, confusion or nausea, please consult your doctor.

Please do not stop taking Solonex Tablet suddenly without consulting your doctor, as it may cause withdrawal symptoms such as irritation, nervousness, difficulty sleeping, headache or having more dreams. Therefore, take Solonex Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking Solonex Tablet , please consult your doctor.

Solonex Tablet is not recommended for patients experiencing seizures, as it may increase the risk of recurring seizures. Therefore, it is advised to inform your doctor if you have a history of fits before taking Solonex Tablet .

Inform your doctor if your symptoms persist or worsen after completing the full course of Solonex Tablet . If you notice any undesirable effects that bother you while taking Solonex Tablet , consult your doctor.

If you miss taking a dose of Solonex Tablet , then take it as soon as you remember. However, if it is time for the next dose, skip the missed dose and continue with the regular dose. Avoid taking a double dose to make up for the missed one.

You are not recommended to stop taking Solonex Tablet even if you feel better, as you may experience unwanted side effects. Take Solonex Tablet as long as advised by a doctor for an effective response. However, contact a doctor if you have any concerns.

Solonex Tablet may cause side effects such as fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, and numbness in the feet or hands. Most of these side effects are temporary and do not require any medical attention, as they will gradually reduce over time. However, contact your doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - SOL0028

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:43 AM IST

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Reference

  1. https://extranet.who.int/prequal/sites/default/files/whopar_files/TB266part3v1.pdf
  2. https://www.drugs.com/mtm/isoniazid.html
  3. https://rwandafda.gov.rw/wp-content/uploads/2023/07/Isoniazid-Tablets-BP-100-mg-PIL.pdf
  4. https://medlineplus.gov/druginfo/meds/a682401.html
  5. https://www.medicines.org.uk/emc/files/pil.9139.pdf

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