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compositionComposition:ISONIAZID-100MG
prescriptionPrescription Medicine

SOLONEX DT 100MG TABLET is used to treat and prevent tuberculosis (TB). It contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, it inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ISONIAZID-100MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

SOLONEX DT 100MG TABLET is used to treat and prevent tuberculosis (TB). SOLONEX DT 100MG TABLET is used in combination with other anti-tuberculosis agents. Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. SOLONEX DT 100MG TABLET does not work against infections caused by the virus.

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, SOLONEX DT 100MG TABLET inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

Use SOLONEX DT 100MG TABLET as prescribed. Use SOLONEX DT 100MG TABLET for as long as your doctor has prescribed it for your child based on his/her medical condition. Sometimes, SOLONEX DT 100MG TABLET may cause side effects such as nausea, vomiting, constipation, difficulty passing urine, numbness, or tingling in the feet or hands. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist or worsen, please consult your doctor.

If your child is allergic to Isoniazid, please inform your doctor. It is important that you complete the entire course of SOLONEX DT 100MG TABLET as prescribed by the doctor, even if your child feels better after taking a few doses, because stopping the drug abruptly may not kill bacteria and may result in a resurgence of tuberculosis.

Uses of SOLONEX DT 100MG TABLET

SOLONEX DT 100MG TABLET is used in the treatment of Tuberculosis (TB). The detailed uses of SOLONEX DT 100MG TABLET are as follows:

  • Treatment of Active Tuberculosis (TB): SOLONEX DT 100MG TABLET is a first-line antitubercular agent used in combination with other drugs to treat active TB infections in children. It works by inhibiting the synthesis of mycolic acids, essential components of the bacterial cell wall, thereby killing Mycobacterium tuberculosis.
  • Latent Tuberculosis Infection (LTBI): SOLONEX DT 100MG TABLET is used as a monotherapy for children who have been exposed to TB but do not show active symptoms. It helps prevent the progression from latent infection to active disease, especially in high-risk paediatric populations.
  • Tuberculous Meningitis: SOLONEX DT 100MG TABLET is included in combination regimens for treating TB meningitis in children. It penetrates the cerebrospinal fluid effectively, making it valuable in managing central nervous system TB infections.
  • Prophylaxis in High-Risk Children: SOLONEX DT 100MG TABLET may be used as a preventive measure for children who are immunocompromised or have been in close contact with TB-positive individuals, reducing the risk of developing active TB.

Key Benefits

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. SOLONEX DT 100MG TABLET prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, SOLONEX DT 100MG TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection. SOLONEX DT 100MG TABLET is used in combination with other anti-tuberculosis agents to treat all forms of tuberculosis caused by Mycobacterium tuberculosis.

Side effects of Solonex Dt 100mg Tablet

Directions for Use

  • SOLONEX DT 100MG TABLET should be administered at least 30 minutes before a meal or 2 hours after a meal as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Disperse the tablet in the suggested amount of water and give the mixture to your child using an oral syringe or measuring cup.
  • Do not store the mixture for later use.
SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, SOLONEX DT 100MG TABLET inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Caution

If your child has liver problems, inform your doctor before using SOLONEX DT 100MG TABLET. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your child’s health condition.

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Kidney

Caution

If your child has kidney problems, inform your doctor before using SOLONEX DT 100MG TABLET. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your child’s health condition.

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Children

Safe if prescribed

Use SOLONEX DT 100MG TABLET for children as prescribed by the paediatrician.

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Heart

Consult your doctor

Please consult your doctor before giving SOLONEX DT 100MG TABLET to your child. Your doctor will prescribe SOLONEX DT 100MG TABLET if the benefits outweigh the risks.

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Geriatrics

Not applicable

SOLONEX DT 100MG TABLET is for paediatric patients only.

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of SOLONEX DT 100MG TABLET may include ataxia, blurred vision, coma, dizziness, dysarthria, hyperreflexia, lactic acidosis, mydriasis, nausea, photophobia, rapid confusion, refractory seizures, tachycardia, and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help in improving the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from a cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.

Have a query?

Drug Warnings

If your child is allergic to Isoniazid, please inform your doctor. If your child feels thirsty all the time and has to go to the toilet often, contact your doctor, as they may have high blood sugar. You are recommended to complete the full course of SOLONEX DT 100MG TABLET as prescribed by the doctor even if your child feels better after 2 weeks of using SOLONEX DT 100MG TABLET as discontinuing the medicine suddenly may not kill bacteria and there might be a relapse of tuberculosis.

Drug-Drug Interactions

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IsoniazidLomitapide
Critical

Drug-Drug Interactions

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IsoniazidLomitapide
Critical
How does the drug interact with Solonex Dt 100mg Tablet:
When Lomitapide is taken with Solonex Dt 100mg Tablet, Solonex Dt 100mg Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Solonex Dt 100mg Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
When Solonex Dt 100mg Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Solonex Dt 100mg Tablet is not recommended, it taken can be taken if prescribed by the doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
When Lovastatin is taken with Solonex Dt 100mg Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Solonex Dt 100mg Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
How does the drug interact with Solonex Dt 100mg Tablet:
Co-administration of Solonex Dt 100mg Tablet with Calcitriol may decrease the effects of Calcitriol.

How to manage the interaction:
Although there is an interaction, calcitriol can be taken with Solonex Dt 100mg Tablet if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
Co-administration of Solonex Dt 100mg Tablet may considerably enhance the blood levels of Tizanidine, which may result in side effects.

How to manage the interaction:
There may be a possibility of interaction between Tizanidine and Solonex Dt 100mg Tablet, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience excessive drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
The combined use of Solonex Dt 100mg Tablet and Simvastatin will enhance the levels of Simvastatin, which increases the risk of side effects.

How to manage the interaction:
Co-administration of Simvastatin and Solonex Dt 100mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Solonex Dt 100mg Tablet:
Taking Solonex Dt 100mg Tablet with Leflunomide can increase the risk and severity of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Solonex Dt 100mg Tablet, it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash, itching, exhaustion, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
Using Phenytoin together with Solonex Dt 100mg Tablet may increase the effects of Phenytoin, which may increase the risk of side effects.

How to manage the interaction:
Although taking Phenytoin and Solonex Dt 100mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience jerky eye movements, slurred speech, loss of balance, shaking, muscle stiffness or weakness, nausea, vomiting, feeling dizzy, fainting, and slow or shallow breathing, consult a doctor immediately. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
Using Solonex Dt 100mg Tablet with Teriflunomide can increase the risk and severity of the side effects of the liver.

How to manage the interaction:
Taking Solonex Dt 100mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to consult a doctor: Fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, nausea, vomiting, abdominal pain, dark urine, light colored stool, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
How does the drug interact with Solonex Dt 100mg Tablet:
When Halothane is taken with Solonex Dt 100mg Tablet, can increase the side affects of liver.

How to manage the interaction:
Co-administration of Solonex Dt 100mg Tablet with Halothane can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, appetite loss, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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No
[ANTI- TUBERCULOSIS]

FAQs

SOLONEX DT 100MG TABLET is used to treat and prevent tuberculosis (TB). SOLONEX DT 100MG TABLET is used in combination with other anti-tuberculosis agents.

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. SOLONEX DT 100MG TABLET prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, SOLONEX DT 100MG TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.

You are recommended to avoid giving foods containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, and mackerel to your child as they may interact with SOLONEX DT 100MG TABLET and cause adverse effects such as sweating, headache, dizziness, light-headedness, flushing (reddening of the skin), fainting due to low blood pressure, uneven, fast or forceful heartbeat.

SOLONEX DT 100MG TABLET is usually not recommended for children with severe liver impairment as it may worsen the condition. Therefore, please inform the doctor if your child has any liver problems before using SOLONEX DT 100MG TABLET.

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