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  3. Solthrip Tablet 10's

Solthrip Tablet 10's, Pack of 10 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Solthrip Tablet is used to treat bacterial infections of the ear, urinary tracts like cystitis (inflammation of the bladder) and the respiratory tract. It contains Trimethoprim, which inhibits bacterial growth. It may cause common side effects such as diarrhoea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

TRIMETHOPRIM-100MG

Manufacturer/Marketer :

MISAE LIFE SCIENCES

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Solthrip Tablet

Solthrip Tablet belongs to the 'antibacterials' class of drugs, primarily used to treat bacterial infections of the ear, urinary tracts like cystitis (inflammation of the bladder) and respiratory tract. Bacterial infection occurs when harmful bacteria grow in the body and cause illness. It can infect any part of the body and multiply very quickly.

Solthrip Tablet contains 'Trimethoprim,' an antibacterial drug. Trimethoprim is a folic acid inhibitor that inhibits tetrahydrofolic acid formation (a folic acid derivative essential for developing proteins and nucleic acids). Thus, Solthrip Tablet prevents the synthesis of bacterial nucleic acids and proteins, which are the primary cursors for carrying out bacteria's vital functions. This process further inhibits bacterial growth.

Like all medicines, Solthrip Tablet also causes side effects, although not everybody gets them. Common side effects of Solthrip Tablet include diarrhoea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache. If any of these effects persist or worsen, seek medical advice promptly.

Brief your medical history to the doctor before starting Solthrip Tablet . Do not use Solthrip Tablet while having vaccinations with live bacterial vaccines (typhoid vaccine) since Solthrip Tablet may affect vaccines' activity. Solthrip Tablet can make your skin more sensitive to the sun; hence, wear sunscreen when you step out. It is advised to consult your doctor if you are pregnant or breastfeeding before taking Solthrip Tablet .

Uses of Solthrip Tablet

Solthrip Tablet is used to treat Bacterial Infections. The detailed uses of Solthrip Tablet are as follows:<br/> • Bacterial Infections: Solthrip Tablet helps treat bacterial illnesses, including pneumonia and bronchitis. The composition of Solthrip Tablet improves efficacy against resistant microorganisms.<br/> • Urinary Tract Infections (UTIs): Solthrip Tablet treats urinary tract infections caused by susceptible bacteria and provides broad-spectrum protection.<br/> • Otitis Media: Solthrip Tablet helps to treat middle ear infections.<br/> • Pneumonia: Solthrip Tablet is also involved in treating pneumonia by efficiently fighting against the microorganisms that cause the condition.

Directions for Use

  • Solthrip Tablet can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Solthrip Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Solthrip Tablet contains 'Trimethoprim,' an antibacterial drug that treats bacterial infections of the ear, urinary tracts like cystitis (inflammation of the bladder), and respiratory tract. It also helps in treating chest infections and acne. Solthrip Tablet is a folic acid inhibitor and inhibits tetrahydrofolic acid formation (a folic acid derivative essential for the formation of proteins and nucleic acids). Thus, Solthrip Tablet prevents the synthesis of bacterial nucleic acids and proteins, which are the primary cursors for carrying out bacteria's vital functions. Solthrip Tablet is also used to prevent the recurrence of urinary tract infections.

How Solthrip Tablet Works

Solthrip Tablet contains 'Trimethoprim,' an antibacterial drug. Trimethoprim is a folic acid inhibitor that inhibits tetrahydrofolic acid formation (a folic acid derivative essential for developing proteins and nucleic acids). Thus, Solthrip Tablet prevents the synthesis of bacterial nucleic acids and proteins, which are the primary cursors for carrying out bacteria's vital functions. This process further inhibits bacterial growth.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Solthrip Tablet
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.

What if I have taken an overdose of Solthrip Tablet

Do not take more than the prescribed dose of Solthrip Tablet as it may cause overdose. The symptoms of overdose include confusion, dizziness, depression, vomiting, nausea, fever, headache, chills, or flu-like symptoms. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Older patients may be more prone to side effects when they have a history of hyperkalemia while using Solthrip Tablet . Please inform your doctor if you are undergoing dialysis treatment since Solthrip Tablet is moderately removed by haemodialysis. Your doctor may schedule the dosage after dialysis. Please undergo an examination to rule out CDAD's chances if you experience diarrhoea following Solthrip Tablet therapy. Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since Solthrip Tablet may affect vaccines' activity. Solthrip Tablet may induce photosensitivity and make your skin more sensitive to the sun; hence, wear sunscreen when you step out. Please seek medical advice if you are pregnant or breastfeeding before taking Solthrip Tablet .

Drug-Drug Interactions

verifiedApollotooltip
TrimethoprimBCG vaccine
Critical
TrimethoprimBenazepril
Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Solthrip Tablet:
Taking Solthrip Tablet with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Solthrip Tablet and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimBenazepril
Severe
How does the drug interact with Solthrip Tablet:
Taking Solthrip Tablet with Benazepril can cause high levels of potassium in the blood.

How to manage the interaction:
Although there is an interaction between benazepril and Solthrip Tablet, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimRamipril
Severe
How does the drug interact with Solthrip Tablet:
Taking Ramipril with Solthrip Tablet can increase the potassium levels in the blood, increasing the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between ramipril and Solthrip Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting your doctor.
TrimethoprimPotassium chloride
Severe
How does the drug interact with Solthrip Tablet:
Taking Potassium chloride with Solthrip Tablet may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood.).

How to manage the interaction:
Although there is a possible interaction between Solthrip Tablet and Potassium chloride, you can take these medicines together if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
TrimethoprimFolic acid
Severe
How does the drug interact with Solthrip Tablet:
Solthrip Tablet may decrease the blood levels and effects of folic acid.

How to manage the interaction:
Although there is a possible interaction between Folic acid and Solthrip Tablet, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
TrimethoprimTetracaine
Severe
How does the drug interact with Solthrip Tablet:
Co-administration of Solthrip Tablet with tetracaine can result in blood disorders.

How to manage the interaction:
Although there is an interaction between Solthrip Tablet and tetracaine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, or shortness of breath. Do not discontinue any medications without consulting a doctor.
TrimethoprimPhenytoin
Severe
How does the drug interact with Solthrip Tablet:
Co-administration of Solthrip Tablet with phenytoin may increase the blood levels and effects of phenytoin.

How to manage the interaction:
Although there is an interaction between Solthrip Tablet and phenytoin but can be taken together if prescribed by doctor. However, if you experience nausea, vomiting, twitching eye movements, blurred vision, difficult to speak, loss of balance or coordination, tremors (shaking of hands legs), and confusion contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.
TrimethoprimEnalapril
Severe
How does the drug interact with Solthrip Tablet:
Enalapril combined with Solthrip Tablet can cause hyperkalemia by elevating blood potassium levels. In severe cases, hyperkalemia can induce muscle paralysis, renal damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of renal or cardiovascular disease.

How to manage the interaction:
Although taking Enalapril together with Solthrip Tablet may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
TrimethoprimPotassium citrate
Severe
How does the drug interact with Solthrip Tablet:
Taking Potassium citrate with Solthrip Tablet may increase potassium levels in the blood, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Solthrip Tablet and Potassium citrate, you can take these medicines together if prescribed by your doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
TrimethoprimPotassium iodide
Severe
How does the drug interact with Solthrip Tablet:
Taking Potassium Iodide with Solthrip Tablet can make high levels of potassium in the blood which can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Potassium iodide and Solthrip Tablet, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Eating grapefruit during antibiotic treatment can prevent the body from properly utilizing Solthrip Tablet . So, avoid intake of grapefruit or grapefruit juice with the antibiotic.
  • Avoid intake of alcoholic beverages with Solthrip Tablet as it can make you dehydrated and affect your sleep. This can make it more challenging for your body to aid the Solthrip Tablet in fighting off infections.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Do not walk barefoot at places like gym showers to prevent bacterial infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Solthrip Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption while taking Solthrip Tablet to prevent unpleasant side-effects, such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

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Pregnancy

Unsafe

Solthrip Tablet is not recommended during pregnancy since it interferes with folic acid formation, which plays a crucial role in developing the unborn baby's brain and spinal cord. Please consult your doctor before taking Solthrip Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Solthrip Tablet is excreted into the breast milk. Please consult your doctor before taking Solthrip Tablet if you are breastfeeding.

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Driving

Unsafe

It is unknown whether Solthrip Tablet affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed. If you experience dizziness or fatigue after taking Solthrip Tablet , do not drive or operate any machinery.

bannner image

Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before taking Solthrip Tablet .

bannner image

Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before taking Solthrip Tablet .

bannner image

Children

Unsafe

Solthrip Tablet is not recommended to children below 12 years.

Have a query?

FAQs

Solthrip Tablet is used to treat bacterial infections of the ear and urinary tract, including cystitis (inflammation of the bladder) and respiratory tract.

Solthrip Tablet contains Trimethoprim, an antibacterial drug. It inhibits tetrahydrofolic acid formation and prevents the synthesis of bacterial nucleic acids and proteins that carry out bacteria's vital functions.

Solthrip Tablet should be used with proper caution and doctor consultation if you have any anaemia (due to folate deficiency), kidney or liver diseases, diabetes, vitamin deficiency (folate or folic acid), blood disorders like bone marrow suppression and G6PD deficiency (a genetic disorder that causes red blood cells to breakdown), mineral imbalances like high potassium levels (hyperkalaemia) or low levels of sodium in the blood, porphyria (a disorder of skin sensitivity to light), and muscle weakness.

Solthrip Tablet can affect the live vaccines, like the typhoid vaccine, and decrease their effectiveness. Please consult a doctor before you start Solthrip Tablet if you are undergoing any vaccinations.

Take this medication 2-3 hours before or after taking iron supplements, multivitamins, calcium supplements, antacids, and laxatives, since these products prevent the absorption of Solthrip Tablet . It is also advised to avoid dairy products like milk, yoghurt, and calcium-enriched juice.

Solthrip Tablet can make your skin more sensitive to the harmful effects of the sunlight. Hence, it is advised to use sunscreen and wear protective clothing while using Solthrip Tablet . It is also recommended to avoid tanning booths and sunlamps.

It is recommended to complete the course of Solthrip Tablet even if you feel better as it is an antibiotic, and stopping it midway may lead to recurring infections. Continue taking Solthrip Tablet for as long as your doctor has prescribed to treat your condition effectually.

Solthrip Tablet is an antibacterial agent used to treat bacterial infections.

No, Solthrip Tablet does not cause addiction. It is not a habit-forming drug.

Solthrip Tablet usually starts working within 24-48 hours and you will feel better within a few days. To treat your condition effectively, keep taking Solthrip Tablet for the prescribed duration.

Consult the doctor if you do not feel better even after completing the course of treatment or if your condition worsens during treatment with Solthrip Tablet .

Common side effects of Solthrip Tablet include diarrhoea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache. If any of these effects persist or worsen, seek medical advice promptly.

Country of origin

India
Other Info - SOL0576

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 21, 2025 | 12:20 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5925.pdf
  2. https://www.drugs.com/mtm/trimethoprim.html
  3. https://www.webmd.com/drugs/2/drug-4083/trimethoprim-oral/details
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