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compositionComposition:TRIMETHOPRIM-100MG
prescription
Prescription Medicine
info
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Metstol 100mg Tablet is used to treat bacterial infections of the ear, urinary tracts like cystitis (inflammation of the bladder) and the respiratory tract. It contains Trimethoprim, which inhibits bacterial growth. It may cause common side effects such as diarrhoea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

TRIMETHOPRIM-100MG

Manufacturer/Marketer :

Renauxe Pharma India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Metstol 100mg Tablet

Metstol 100mg Tablet is an oral medicine used to treat bacterial infections, most commonly acute urinary tract infections. It works by stopping the growth of the specific bacteria causing discomfort in your bladder and kidneys. This helps your body clear the infection quickly and effectively.

You will typically take this medicine once or twice a day as prescribed by your doctor. It is important to take it at the same times each day and complete the entire course, even if you start to feel better after a few days. You can take this medicine with or without food, but taking it with a meal can help prevent any mild stomach upset. Drinking plenty of water during your treatment is also highly recommended to keep your urinary tract clean.

Most people tolerate this medication well, though some may experience mild side effects like nausea, vomiting, or changes in taste. However, you must contact your doctor immediately if you experience severe symptoms such as a sudden skin rash, peeling skin, severe diarrhoea, or muscle weakness.

Before starting this treatment, talk to your doctor if you have kidney disease, liver damage, blood disorders, or a history of folate deficiency. Do not take this if you have severe kidney or liver disease or if you have a known history of severe blood disorders like anaemia caused by folate deficiency.

This medicine can interact with blood thinners, certain blood pressure drugs, and medications that affect your kidneys, altering how they work or increasing side effect risks. Avoid drinking alcohol during treatment as it can increase dehydration and dizziness, and consult your doctor before taking this if you are pregnant, breastfeeding, or an elderly individual.

Uses of Metstol 100mg Tablet

Metstol 100mg Tablet is used to treat bacterial infections. The detailed uses of Metstol 100mg Tablet are as follows:

  • Urinary Tract Infections (UTIs): Metstol 100mg Tablet is highly effective in treating bacterial infections of the bladder and kidneys, helping to eliminate the bacteria responsible for painful urination and urinary frequency.
  • Middle Ear Infections (Otitis Media): This medicine helps clear bacterial infections in the middle ear, particularly when standard first-line therapies are not suitable.
  • Traveller's Diarrhoea: It can be used to treat or prevent bacterial infections of the digestive tract caused by susceptible bacteria when travelling to high-risk areas.

Key Benefits

Metstol 100mg Tablet provides reliable relief from the painful and disruptive symptoms of bacterial infections. By targeting the source of the infection, it helps you recover quickly so you can return to your normal daily routine without discomfort.

  • Rapid Symptom Relief: Most patients notice a significant reduction in burning pain, urgency, and pelvic discomfort within the first 24 to 48 hours of treatment.
  • Targeted Bacterial Defence: The medication focuses directly on the harmful bacteria causing the infection, minimising damage to the rest of your body's natural systems.
  • Convenient Oral Administration: Available in easy-to-swallow tablets, it offers a simple and non-invasive way to treat infections without the need for clinical injections.
Side effects of Metstol 100mg Tablet
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.

Directions for Use

  • Metstol 100mg Tablet can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Metstol 100mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Metstol 100mg Tablet Works

Metstol 100mg Tablet contains trimethoprim, which works by stopping bacteria from producing folic acid, which is a vital nutrient they need to grow, multiply, and copy their DNA. Without folic acid, the bacteria cannot survive or replicate, which stops the infection from spreading throughout your body. This allows your natural immune system to easily target and destroy the remaining bacteria. Because human cells absorb folic acid directly from the food we eat rather than making it themselves, this medicine specifically targets bacterial cells while leaving your body's healthy cells unharmed.
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Alcohol

Unsafe

Avoid alcohol consumption while taking Metstol 100mg Tablet to prevent unpleasant side-effects, such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

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Pregnancy

Unsafe

Metstol 100mg Tablet is not recommended during pregnancy since it interferes with folic acid formation, which plays a crucial role in developing the unborn baby's brain and spinal cord. Please consult your doctor before taking Metstol 100mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Metstol 100mg Tablet is excreted into the breast milk. Please consult your doctor before taking Metstol 100mg Tablet if you are breastfeeding.

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Driving

Unsafe

It is unknown whether Metstol 100mg Tablet affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed. If you experience dizziness or fatigue after taking Metstol 100mg Tablet, do not drive or operate any machinery.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before taking Metstol 100mg Tablet.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before taking Metstol 100mg Tablet.

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Children

Unsafe

Metstol 100mg Tablet is not recommended to children below 12 years.

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Heart

Consult your doctor

Please consult your doctor before using Metstol 100mg Tablet if you have pre-existing heart problems. Your doctor will prescribe Metstol 100mg Tablet if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Metstol 100mg Tablet to geriatric patients. Your doctor will prescribe Metstol 100mg Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Metstol 100mg Tablet

If you suspect an accidental overdose, seek immediate medical attention. Symptoms of an overdose may include severe nausea, vomiting, dizziness, headache, confusion, or a feeling of extreme tiredness.

Diet & Lifestyle Advise

  • Drink plenty of water: Increase your daily intake of fluids, particularly water, to help flush bacteria out of your urinary tract and keep your kidneys working efficiently.
  • Avoid bladder irritants: While treating a urinary tract infection, avoid consuming alcohol, caffeine, carbonated drinks, and highly spicy foods, as these can irritate your bladder and prolong discomfort.
  • Be careful with folic acid: Avoid taking high-dose folic acid supplements or multivitamins containing folic acid while taking this medicine, unless specifically advised by your doctor, as it can make the treatment less effective.
  • Protect your skin: This medicine can make your skin more sensitive to the sun. Wear protective clothing, apply sunscreen, and limit your exposure to direct sunlight and tanning beds.
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How Soon It Starts Working

The time required for Metstol 100mg Tablet to start to work: The time required for Metstol 100mg Tablet to show its action is not clinically established. The time for which the effects of Metstol 100mg Tablet last: The duration of action for Metstol 100mg Tablet is not clinically established.

What if you forget to take Metstol 100mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure what to do, talk to your doctor or pharmacist.

Storage

•Store Metstol 100mg Tablet tablets at room temperature, between 15°C and 30°C (59°F to 86°F), in a dry place away from direct heat and light. •If you are using a liquid suspension, store it according to the package instructions, keep it in a cool place.

Drug Warnings

  • Always complete the full course of therapy prescribed by your doctor, even if you feel completely better within a couple of days.
  • If you experience a skin rash or itching at any point during your treatment, stop taking the medicine and contact your doctor immediately.
  • Inform your doctor if you have a history of anaemia or low blood folate levels before starting this medicine.
  • Let any healthcare provider or lab technician know you are taking this medication before you have blood or urine tests, as it can interfere with certain test results.
  • If you are taking this medicine long-term, your doctor may require regular blood tests to monitor your kidney function and blood cell counts.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (like warfarin): Metstol 100mg Tablet can increase the blood-thinning effect, which may raise your risk of bleeding.
  • Blood pressure medications (like ACE inhibitors or ARBs): Combining these can dangerously increase potassium levels in your blood, potentially affecting your heart rhythm.
  • Methotrexate: This combination can increase the levels of methotrexate in your body, raising the risk of severe side effects like bone marrow suppression.
  • Phenytoin: Metstol 100mg Tablet may increase the levels of this seizure medicine in your system, potentially leading to toxic side effects.
TrimethoprimBCG vaccine
Critical
TrimethoprimIrbesartan
Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Metstol 100mg Tablet:
Taking Metstol 100mg Tablet with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Metstol 100mg Tablet and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimIrbesartan
Severe
How does the drug interact with Metstol 100mg Tablet:
Taking Irbesartan with Metstol 100mg Tablet may increase potassium levels in the blood and kidney problems.

How to manage the interaction:
Although taking Irbesartan with Metstol 100mg Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult your doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
TrimethoprimLevobupivacaine
Severe
How does the drug interact with Metstol 100mg Tablet:
Taking Metstol 100mg Tablet with Levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Levobupivacaine and Metstol 100mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, headache, dizziness, fatigue, or difficulty breathing, it's best to contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrimethoprimProcaine
Severe
How does the drug interact with Metstol 100mg Tablet:
Co-administration of Metstol 100mg Tablet with procaine may increase the risk of blood disorders.

How to manage the interaction:
Taking Metstol 100mg Tablet with Procaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like gray skin, feeling sick, headache, dizziness, tiredness, trouble breathing, fast heartbeat, or feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrimethoprimIvacaftor
Severe
How does the drug interact with Metstol 100mg Tablet:
When Metstol 100mg Tablet is taken with Ivacaftor, the amount of Metstol 100mg Tablet in the blood increases.

How to manage the interaction:
Taking Metstol 100mg Tablet with Ivacaftor together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting your doctor.
TrimethoprimLisinopril
Severe
How does the drug interact with Metstol 100mg Tablet:
Taking Lisinopril with Metstol 100mg Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although taking Metstol 100mg Tablet and Lisinopril together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
TrimethoprimMethotrexate
Severe
How does the drug interact with Metstol 100mg Tablet:
Coadministration of Metstol 100mg Tablet with methotrexate can increase the risk or severity of blood disorders.

How to manage the interaction:
Although there is a possible interaction between Metstol 100mg Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
TrimethoprimAzilsartan medoxomil
Severe
How does the drug interact with Metstol 100mg Tablet:
Coadministration of Azilsartan medoxomil with Metstol 100mg Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between azilsartan medoxomil and Metstol 100mg Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, or tingling in your hands and feet. Do not discontinue any medications without a doctor's advice.
TrimethoprimRamipril
Severe
How does the drug interact with Metstol 100mg Tablet:
Taking Ramipril with Metstol 100mg Tablet can increase the potassium levels in the blood, increasing the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between ramipril and Metstol 100mg Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting your doctor.
TrimethoprimCandesartan
Severe
How does the drug interact with Metstol 100mg Tablet:
Taking Metstol 100mg Tablet with candesartan can increase the risk of hyperkalemia (high potassium levels in the blood) and kidney problems.

How to manage the interaction:
Although there is an interaction between candesartan and Metstol 100mg Tablet, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Metstol 100mg Tablet when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Metstol 100mg Tablet is used to treat bacterial infections of the ear and urinary tract, including cystitis (inflammation of the bladder) and respiratory tract.
Metstol 100mg Tablet contains Trimethoprim, an antibacterial drug. It inhibits tetrahydrofolic acid formation and prevents the synthesis of bacterial nucleic acids and proteins that carry out bacteria's vital functions.
Metstol 100mg Tablet should be used with proper caution and doctor consultation if you have any anaemia (due to folate deficiency), kidney or liver diseases, diabetes, vitamin deficiency (folate or folic acid), blood disorders like bone marrow suppression and G6PD deficiency (a genetic disorder that causes red blood cells to breakdown), mineral imbalances like high potassium levels (hyperkalaemia) or low levels of sodium in the blood, porphyria (a disorder of skin sensitivity to light), and muscle weakness.
Metstol 100mg Tablet can affect the live vaccines, like the typhoid vaccine, and decrease their effectiveness. Please consult a doctor before you start Metstol 100mg Tablet if you are undergoing any vaccinations.
Take this medication 2-3 hours before or after taking iron supplements, multivitamins, calcium supplements, antacids, and laxatives, since these products prevent the absorption of Metstol 100mg Tablet. It is also advised to avoid dairy products like milk, yoghurt, and calcium-enriched juice.
It is recommended to complete the course of Metstol 100mg Tablet even if you feel better as it is an antibiotic, and stopping it midway may lead to recurring infections. Continue taking Metstol 100mg Tablet for as long as your doctor has prescribed to treat your condition effectually.
No, Metstol 100mg Tablet does not cause addiction. It is not a habit-forming drug.
Consult the doctor if you do not feel better even after completing the course of treatment or if your condition worsens during treatment with Metstol 100mg Tablet.
Common side effects of Metstol 100mg Tablet include diarrhoea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache. If any of these effects persist or worsen, seek medical advice promptly.
You should avoid alcohol during your treatment. Alcohol can dehydrate your body, make urinary tract symptoms worse, and increase the risk of side effects like dizziness or nausea. Talk to your doctor or pharmacist if you have concerns.
Yes. Like many other antibiotics, this medicine can alter the balance of natural bacteria in your body, allowing yeast to grow. This can cause vaginal itching or discharge. Talk to your doctor or pharmacist if you notice these symptoms.
This medicine is generally not recommended during the first trimester of pregnancy because it can interfere with folic acid, which is critical for the baby's early development. If you are pregnant or planning to become pregnant, talk to your doctor or pharmacist to discuss safer options.
You can take this medication with or without food. If you find that the medicine upsets your stomach or causes mild nausea, taking it with a meal or snack can help prevent this. Talk to your doctor or pharmacist for personalised advice.
No, this medicine is an antibiotic that only targets bacterial infections. It will not work for viral illnesses like the common cold, flu, or acute bronchitis. Using antibiotics when they are not needed can lead to bacterial resistance.
Yes, it can make your skin more sensitive to ultraviolet (UV) light, which increases your risk of sunburn. It is best to wear sunscreen and protective clothing and avoid direct sun exposure or tanning beds while taking it. Talk to your doctor if you develop a sunburn-like rash.
Take the missed dose as soon as you remember. If it is close to the time for your next scheduled dose, skip the missed dose and continue with your normal schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you have questions about your schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

33/396 C, Mrra- 48A,Mannarakkara Road End Punnurunni East, Vyttila P.O Ernakulam Kl 682019 In
Other Info - ME84678
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