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  3. Spasrine 80 mg/250 mg Tablet

Spasrine 80 mg/250 mg Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Spasrine 80 mg/250 mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. It contains Drotaverine and Mefenamic acid, which works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Also, it blocks the effect of chemical messengers that cause pain and inflammation. In some cases, it may cause common side effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DROTAVERINE-80MG + MEFENAMIC ACID-250MG

Manufacturer/Marketer :

Meridian Medicare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Spasrine 80 mg/250 mg Tablet

Spasrine 80 mg/250 mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Spasrine 80 mg/250 mg Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Spasrine 80 mg/250 mg Tablet helps in relieving pain.

You are advised to take Spasrine 80 mg/250 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have/had asthma, peptic ulcers, porphyria, or bleeding problems. Consult your doctor if you are pregnant or breastfeeding. Spasrine 80 mg/250 mg Tablet may cause dizziness, so drive with caution. Spasrine 80 mg/250 mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Spasrine 80 mg/250 mg Tablet

Spasrine 80 mg/250 mg Tablet is used in pain management treatments. The detailed uses of Spasrine 80 mg/250 mg Tablet are as follows:

  • Relief from Menstrual Cramps: Spasrine 80 mg/250 mg Tablet is frequently used to reduce extreme menstrual pain, which eases period discomfort and cramping.
  • Abdominal Pain Treatment: It can help relieve muscle spasms in the gastrointestinal tract and effectively helps to manage abdominal pain due to various conditions.
  • Postoperative Pain Management: Spasrine 80 mg/250 mg Tablet is occasionally recommended to help manage pain after surgery, especially in cases when muscle spasms are present.
  • Improving Gastrointestinal Conditions: Spasrine 80 mg/250 mg Tablet can also be used to alleviate pain and discomfort caused by gastrointestinal conditions, including irritable bowel syndrome.

Directions for Use

• Take Spasrine 80 mg/250 mg Tablet with food to avoid stomach upset or as advised by a doctor. • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety. • Swallow the medicine as a whole with glass of water. • Do not crush, break, or chew it.

Medicinal Benefits

Spasrine 80 mg/250 mg Tablet is a combination of two drugs: Drotaverine and Mefenamic acid. Spasrine 80 mg/250 mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Drotaverine is an antispasmodic that reduces calcium reuptake by the cells, thereby correcting the calcium levels in the body and relieving contractions associated with smooth muscles. Mefenamic acid is an NSAID which works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Spasrine 80 mg/250 mg Tablet helps in relieving pain.

How Spasrine 80 mg/250 mg Tablet Works

Spasrine 80 mg/250 mg Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Spasrine 80 mg/250 mg Tablet helps in relieving pain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Spasrine 80 mg/250 mg Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Spasrine 80 mg/250 mg Tablet

Do not take more than the prescribed dose of Spasrine 80 mg/250 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Spasrine 80 mg/250 mg Tablet if you are allergic to any of its contents. Inform your doctor if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. If you have had any recent heart surgery, do not take Spasrine 80 mg/250 mg Tablet unless prescribed by the doctor, as Spasrine 80 mg/250 mg Tablet may increase the risk of heart attack or stroke. Inform your doctor if you have/had asthma, peptic ulcers, porphyria, bleeding problems, liver or kidney impairment. Consult your doctor if you are pregnant or breastfeeding. Spasrine 80 mg/250 mg Tablet may cause dizziness, so drive only if you are alert. Spasrine 80 mg/250 mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol as it could lead to increased drowsiness and may increase the risk of stomach bleeding. Stop taking Spasrine 80 mg/250 mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Spasrine 80 mg/250 mg Tablet unless prescribed.

Drug-Drug Interactions

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Mefenamic acidKetorolac
Critical
Mefenamic acidMeloxicam
Critical

Drug-Drug Interactions

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Mefenamic acidKetorolac
Critical
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Coadministration of Spasrine 80 mg/250 mg Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Spasrine 80 mg/250 mg Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidMeloxicam
Critical
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Co-administration of Spasrine 80 mg/250 mg Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Spasrine 80 mg/250 mg Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidPrasugrel
Severe
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Co-administration of Spasrine 80 mg/250 mg Tablet with Prasugrel can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Spasrine 80 mg/250 mg Tablet with Prasugrel together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidMethotrexate
Severe
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Coadministration of Spasrine 80 mg/250 mg Tablet with Methotrexate may increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between Spasrine 80 mg/250 mg Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Mefenamic acidTacrolimus
Severe
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Coadministration of Spasrine 80 mg/250 mg Tablet with Tacrolimus can increase the risk of kidney problems.

How to manage the interaction:
Taking Spasrine 80 mg/250 mg Tablet with Tacrolimus together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidDeferasirox
Severe
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Coadministration of Spasrine 80 mg/250 mg Tablet with Deferasirox can increase the risk or severity of gastric bleeding.

How to manage the interaction:
Taking Spasrine 80 mg/250 mg Tablet with Deferasirox together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidEdoxaban
Severe
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Using Edoxaban together with Spasrine 80 mg/250 mg Tablet may increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Spasrine 80 mg/250 mg Tablet and Edoxaban together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, it's important to contact a doctor right away - problems with bleeding, dizziness, black or tarry stools, severe headache, weakness, or vomiting. Do not stop using any medications without talking to a doctor.
Mefenamic acidWarfarin
Severe
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Coadministration of Spasrine 80 mg/250 mg Tablet with Warfarin can increase the risk of bleeding.

How to manage the interaction:
Taking Spasrine 80 mg/250 mg Tablet with Warfarin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Mefenamic acidLithium
Severe
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Co-administration of Spasrine 80 mg/250 mg Tablet with Lithium can increase Lithium levels in the body.

How to manage the interaction:
Taking Spasrine 80 mg/250 mg Tablet with Lithium together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst, and/or increased urination, contact a doctor. Do not stop using any medications without talking to a doctor.
Mefenamic acidNaproxen
Severe
How does the drug interact with Spasrine 80 mg/250 mg Tablet:
Coadministration of Spasrine 80 mg/250 mg Tablet with Naproxen can increase the risk or severity of stomach bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Spasrine 80 mg/250 mg Tablet with Naproxen together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Spasrine 80 mg/250 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Spasrine 80 mg/250 mg Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Spasrine 80 mg/250 mg Tablet if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Spasrine 80 mg/250 mg Tablet may cause drowsiness. Drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

Spasrine 80 mg/250 mg Tablet should not be given to children as the safety and effectiveness were not established.

Have a query?

FAQs

Spasrine 80 mg/250 mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery.

Spasrine 80 mg/250 mg Tablet contains Drotaverine and Mefenamic acid. Drotaverine works by relieving contractions associated with smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.

Diarrhoea might be a side-effect of Spasrine 80 mg/250 mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

Dry mouth could be a side-effect of Spasrine 80 mg/250 mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not take Spasrine 80 mg/250 mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Take Spasrine 80 mg/250 mg Tablet only for as long as your doctor has prescribed it.

Spasrine 80 mg/250 mg Tablet is generally prescribed for short durations and can be discontinued after pain relief. However, you are advised to continue taking Spasrine 80 mg/250 mg Tablet for as long as your doctor has prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Spasrine 80 mg/250 mg Tablet.

Spasrine 80 mg/250 mg Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Spasrine 80 mg/250 mg Tablet only as prescribed, and do not overdose.

Spasrine 80 mg/250 mg Tablet may cause dizziness, so drive with caution and only if you are alert. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Stop taking Spasrine 80 mg/250 mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.

No, do not take Spasrine 80 mg/250 mg Tablet on an empty stomach. Take it with food to prevent stomach upset.

Spasrine 80 mg/250 mg Tablet usually starts working within an hour. However, this might vary individually based on the physical condition.

The doctor will determine the daily dose of Spasrine 80 mg/250 mg Tablet based on your condition. Please consult the doctor if you have any concerns.

Spasrine 80 mg/250 mg Tablet is a combination medicine containing Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). It is used to relieve abdominal pain associated with various conditions.

Yes, Spasrine 80 mg/250 mg Tablet is safe if taken in the dose and duration prescribed by the doctor.

Yes, Spasrine 80 mg/250 mg Tablet may cause nausea and vomiting as a side effect. If you have nausea and vomiting, get fresh air, take sips of water regularly, and eat smaller, frequent meals. Consult the doctor if the condition persists or worsens.

No, do not take a higher than the recommended dose of Spasrine 80 mg/250 mg Tablet as it may cause overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Store Spasrine 80 mg/250 mg Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.

Yes, Spasrine 80 mg/250 mg Tablet can be taken with food. Taking Spasrine 80 mg/250 mg Tablet with food helps prevent stomach upset.

Common side effects of Spasrine 80 mg/250 mg Tablet are gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Spasrine 80 mg/250 mg Tablet can be used during pregnancy or breastfeeding if advised by the doctor. The doctor will prescribe Spasrine 80 mg/250 mg Tablet only if the benefits outweigh the risks.

Do not take Spasrine 80 mg/250 mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Take Spasrine 80 mg/250 mg Tablet only for as long as your doctor has prescribed it.

If you miss a dose of Spasrine 80 mg/250 mg Tablet, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Country of origin

India
Other Info - SP37416

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 5, 2025 | 1:06 PM IST

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Reference

  1. https://www.bionova.co.in/drotafix-tablet.html
  2. https://www.ravimiregister.ee/Data/PIL_ENG/PIL_11232_ENG.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/015034s040lbl.pdf
  4. https://www.drugs.com/cdi/mefenamic-acid.html
  5. https://www.hpra.ie/img/uploaded/swedocuments/eec4b0f8-a82a-4ba9-8e04-d411ee4d7b95.pdf
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