What is the use of Spegra Tablet ?

Spegra Tablet is indicated for the treatment of HIV-1 infection.

How does Spegra Tablet work?

Spegra Tablet works by inhibiting the replication of viral DNA and by preventing it from being integrated into the human body. Thereby, Spegra Tablet helps treat HIV infection.

I suffer from hepatitis. Can I take Spegra Tablet ?

It is not known if Spegra Tablet is safe for patients who have HIV-1 and hepatitis-B infections. Please consult your doctor for any concerns.

Can I stop taking Spegra Tablet on my own?

Do not stop taking Spegra Tablet without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking Spegra Tablet for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Spegra Tablet .

Does Spegra Tablet cause lactic acidosis?

Spegra Tablet might cause lactic acidosis (excess of lactic acid in the blood). Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, or deep rapid breathing.

What if I forget to take Spegra Tablet ?

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

What are the precautions that I should take while on Spegra Tablet ?

Avoid nursing while receiving Spegra Tablet therapy. Avoid alcohol consumption. It is critical to engage in safe sex to avoid transferring HIV to your partner.

What information should I provide my doctor before taking the Spegra Tablet ?

Before taking the Spegra Tablet , let your doctor know about all your medical conditions, sensitivities, and all the medications you are using. And inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How long should I take Spegra Tablet ?

The duration of treatment depends on including medical condition and response to the treatment.

What does the usual recommend dose Spegra Tablet ?

The recommended dosage of Spegra Tablet is one tablet taken orally once daily. But dosage may vary depending on various factors including medical condition and response to the treatment.

What are the key active ingredients present in Spegra Tablet ?

Dolutegravir, Emtricitabine and Tenofovir Alafenamide are the key active components present in it.

Will a higher than the recommended dose of Spegra Tablet be more effective?

Taking more than the recommended dosage does not provide additional pain relief and can increase the risk of adverse effects.

Can I drink alcohol while taking Spegra Tablet ?

Avoid consuming alcohol along with Spegra Tablet as it could lead to adverse effects.

Spegra Tablet 30's

₹3954.5*

MRP ₹4822.5

18% off

₹4099.12*

MRP ₹4822.5

15% CB

₹723.38 cashback(15%)

Free Delivery

With Circle membership

(Inclusive of all Taxes)

This offer price is valid on orders above ₹800. Apply coupon PHARMA10/PHARMA18 (excluding restricted items)

Written By Lakshmithulasi Yarragunta ,

Reviewed By Santoshini Reddy G , M Pharmacy

Spegra Tablet belongs to the class of antiretroviral drugs used in the treatment of HIV-1 infection. This combination medicine work by inhibiting the HIV-1 reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. Common side effects include dizziness, headache, diarrhoea, nausea, vomiting, rashes, trouble sleeping, and feeling weak

Know Your Delivery Time

Provide Delivery Location

Selected Pack Size:30

30
₹3954.5
(₹131.82 per unit)
In Stock
90
₹11864.2
(₹131.82 per unit)
In Stock

Prescription drug

Whats That

23 people bought

in last 7 days

Secure Payment

India's Most Trusted Pharmacy

Genuine Products

About Spegra Tablet

Spegra Tablet is used for the treatment of HIV-1 infection in adults and children above 12 years weighing at least 40kgs. HIV is a virus that attacks the body's immune system, making it compromised and susceptible to various infections and diseases.

Spegra Tablet contains 'Dolutegravir, Emtricitabine and Tenofovir alafenamide'. Spegra Tablet works by interfering with the work of HIV-1 reverse transcriptase enzymes, which are necessary for the replication of the virus. Together, Spegra Tablet helps in treating HIV infection.

Take Spegra Tablet as prescribed. In some cases, Spegra Tablet may cause certain side effects such as trouble sleeping, headache, nausea, and tiredness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

Consult your doctor if you are pregnant, or planning to get pregnant. Avoid breastfeeding while taking Spegra Tablet . Spegra Tablet does not help reduce the risk of getting HIV-1 infection by sexual contact; therefore, it is important to practise safe sex to avoid transmitting HIV to your partner. Avoid alcohol consumption while on treatment with Spegra Tablet .

Uses of Spegra Tablet

Treatment of HIV-1 infection

Directions for Use

Swallow Spegra Tablet as a whole with water. Do not crush, chew or break it.

Medicinal Benefits

Spegra Tablet is an anti-retroviral drug used in the treatment of HIV-1 infection. Spegra Tablet works by interfering with the replication of HIV and preventing its further progression. It contains Dolutegravir, Emtricitabine and Tenofovir alafenamide. Dolutegravir works by blocking HIV integrase, which is responsible for integrating viral DNA into the host cell. Thus, it inhibits the integration of the viral component into the human body cells. Emtricitabine works by inhibiting reverse transcriptase, which is responsible for transcribing RNA to DNA. By blocking this action, emtricitabine prevents the proliferation of the virus. Tenofovir alafenamide blocks the enzyme polymerase, thereby preventing aggregation of viral components and terminating the DNA chain, thus effectively nipping viral replication in the bud.

How Spegra Tablet Works

Spegra Tablet contains 'Dolutegravir, Emtricitabine and Tenofovir alafenamide'. Spegra Tablet works by interfering with the work of HIV-1 reverse transcriptase enzymes, which are necessary for the replication of the virus. Together, Spegra Tablet helps in treating HIV infection.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Spegra Tablet

Do not take more than the prescribed dose of Spegra Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform the doctor if you are allergic to any of the components of Spegra Tablet . Consult your doctor if you are pregnant, or planning to get pregnant before taking Spegra Tablet . Avoid breastfeeding while on treatment with Spegra Tablet . Avoid alcohol consumption. It is important to practise safe sex to avoid transmitting HIV to your partner. Inform your doctor if you have liver problems, hepatitis infections, heart or kidney problems. Keep your doctor informed about your health condition and medications to rule out any interactions.

Drug-Drug Interactions

DolutegravirDofetilide

Critical

EmtricitabineLamivudine

Critical

Drug-Drug Interactions

Login/Sign Up

DolutegravirDofetilide

Critical

How does the drug interact with Spegra Tablet:
Taking Spegra Tablet with dofetilide may possibly reduce the blood levels and effects of Spegra Tablet. This can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Spegra Tablet with Dofetilide is not recommended, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.

EmtricitabineLamivudine

Critical

How does the drug interact with Spegra Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Spegra Tablet with Lamivudine is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.

Tenofovir disoproxilStreptozocin

Critical

How does the drug interact with Spegra Tablet:
Combining Spegra Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Spegra Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.

Tenofovir disoproxilDidanosine

Critical

How does the drug interact with Spegra Tablet:
Coadministration of Didanosine with Spegra Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Spegra Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

DolutegravirSodium bicarbonate

Severe

How does the drug interact with Spegra Tablet:
Co-administration of Sodium bicarbonate and Spegra Tablet reduces the levels of Spegra Tablet, resulting in reduced effectiveness.

How to manage the interaction:
Although taking Spegra Tablet and Sodium bicarbonate together can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience symptoms like fever, chills, diarrhea, sore throat, muscle aches, red or inflamed skin, and pain or burning during urination, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

DolutegravirMagnesium oxide

Severe

How does the drug interact with Spegra Tablet:
Taking Spegra Tablet with magnesium oxide can reduce the effectiveness of Spegra Tablet.

How to manage the interaction:
Taking Magnesium oxide with Spegra Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, take Spegra Tablet at least two hours before or six hours after the magnesium oxide dose. Do not stop using any medications without talking to a doctor.

DolutegravirDidanosine

Severe

How does the drug interact with Spegra Tablet:
Co-administration of Spegra Tablet with Didanosine can reduce the effectiveness of Spegra Tablet.

How to manage the interaction:
Although taking Spegra Tablet and Didanosine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Spegra Tablet at least two hours before or six hours after the didanosine dose. Do not discontinue using any medications without consulting a doctor.

DolutegravirCalcium glubionate

Severe

How does the drug interact with Spegra Tablet:
Co-administration of Spegra Tablet with Calcium glubionate can reduce the effectiveness of Spegra Tablet.

How to manage the interaction:
Taking Spegra Tablet with Calcium glubionate together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, take Spegra Tablet at least two hours before or six hours after calcium citrate. Do not discontinue the medication without consulting a doctor.

DolutegravirEtravirine

Severe

How does the drug interact with Spegra Tablet:
Taking Spegra Tablet with etravirine can reduce the blood levels and effectiveness of Spegra Tablet.

How to manage the interaction:
Although taking Spegra Tablet and Etravirine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting a doctor.

DolutegravirFerric maltol

Severe

How does the drug interact with Spegra Tablet:
Taking Spegra Tablet with ferric maltol can reduce the effectiveness of Spegra Tablet.

How to manage the interaction:
Although taking Spegra Tablet and Ferric maltol together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Spegra Tablet either two hours before or six hours after taking a dose of Ferric maltol. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

DOLUTEGRAVIR-50MG+EMTRICITABINE-200MG+TENOFOVIR ALAFENAMIDE-25MGHerbal products/medicines

Moderate

Drug-Food Interactions

Login/Sign Up

DOLUTEGRAVIR-50MG+EMTRICITABINE-200MG+TENOFOVIR ALAFENAMIDE-25MGHerbal products/medicines

Moderate

Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Consuming St.John's Wort while taking Spegra Tablet can increase the risk of side effects. Avoid consuming St.John's Wort with Spegra Tablet as it can lead to an interaction.

Diet & Lifestyle Advise

Practise safe sex to prevent transmitting HIV to your partner. Educate yourself and your partner about pre and post-exposure prophylaxis and ART (anti-retroviral therapy). Use a condom as far as possible.
Meditation and yoga have also proven very effective in helping HIV patients maintain a healthy attitude and body.
Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods.
Take good care of your oral hygiene. HIV often affects the mouth and causes sores. See a dentist regularly. Brush, floss and scrape your tongue well and keep your mouth clean.
Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.

Habit Forming

No

Therapeutic Class

ANTIVIRALS