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compositionComposition:MEFENAMIC ACID-250MG+TRANEXAMIC ACID-500MG
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Prescription Medicine
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Stat-B Tablet is used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Additionally, it is used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headaches. It contains two medicines, namely Tranexamic acid and Mefenamic acid. It may cause common side effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

MEFENAMIC ACID-250MG+TRANEXAMIC ACID-500MG

Manufacturer/Marketer :

Sumac Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Stat-B Tablet

Stat-B Tablet is a combination medicine used to treat heavy menstrual bleeding accompanied by painful period cramps. It helps manage excessive blood loss and relieves pelvic pain during your menstrual cycle. Stat-B Tablet is specifically prescribed for temporary use during your period days and is not meant for long-term daily consumption.

You should take Stat-B Tablet only during your menstrual period, exactly as advised by your doctor. It is highly recommended to take Stat-B Tablet with food or immediately after a meal to protect your stomach lining from irritation. Making simple lifestyle adjustments, such as staying well-hydrated and using a heating pad on your lower abdomen, can also support your recovery during treatment.

While taking Stat-B Tablet , some people may experience mild side effects such as nausea, heartburn, or temporary digestive upset. If you experience any severe symptoms, such as sudden changes in your vision, severe calf pain, or difficulty breathing, stop taking the medication and consult your doctor immediately.

Before starting Stat-B Tablet , you must talk to your doctor if you have a history of kidney problems, asthma, or stomach ulcers. Do not take this if you have active blood clots, a history of deep vein thrombosis, or a known allergy to aspirin or other pain-relieving medicines.

Stat-B Tablet can interact with oral contraceptives, blood thinners, and alcohol, which may increase your risk of bleeding or blood clots. If you are pregnant, planning a pregnancy, or breastfeeding, consult your healthcare provider before taking this medication to ensure it is safe for you.

Uses of Stat-B Tablet

Stat-B Tablet is used in the treatment of dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). The detailed uses of Stat-B Tablet are as follows:

  • Menstrual cramps and pain (dysmenorrhea): Stat-B Tablet relieves painful lower abdominal cramps and discomfort that often accompany heavy periods.
  • Heavy menstrual bleeding (menorrhagia): Stat-B Tablet helps reduce the excessive volume of blood loss during your period, making your cycle more manageable.

Key Benefits

Stat-B Tablet helps manage heavy menstrual bleeding and associated menstrual pain, improving comfort and supporting normal daily activities. By reducing excessive blood loss and relieving cramps, it helps make menstrual cycles more manageable.
Benefits may include:
• Helps reduce heavy menstrual bleeding.
• Relieves menstrual cramps and pelvic pain.
• Supports greater comfort during menstrual periods.
• Helps reduce fatigue and weakness associated with excessive blood loss.
• May help lower the risk of iron deficiency related to heavy menstrual bleeding.
• Improves ability to carry out daily activities with fewer menstrual-related disruptions.
 

Side effects of Stat-B Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

Please read these instructions carefully before taking your medication:

  • Swallow the Stat-B Tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medicine is absorbed.
  • Always take Stat-B Tablet with or after food to minimize the risk of stomach upset.
  • Only take this medication on the days you are actively bleeding or experiencing severe pain during your period. Do not take it on non-period days.
  • Always follow your doctor's exact instructions regarding how many days to take this medication.

 

How Stat-B Tablet Works

Stat-B Tablet contains Tranexamic Acid and Mefenamic Acid. • Tranexamic Acid: It helps reduce excessive menstrual bleeding by preventing blood clots from breaking down too quickly. This helps control blood loss during periods. • Mefenamic Acid: It helps relieve menstrual pain, cramps, and inflammation by reducing the substances in the body that cause pain and uterine contractions.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Stat-B Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Stat-B Tablet if you are breastfeeding, your doctor will decide if Stat-B Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Stat-B Tablet may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Stat-B Tablet should not be given to children as the safety and effectiveness were not established.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

Stat-B Tablet can be given in elderly patients with caution and only if prescribed by the doctor.

What if I have taken an overdose of Stat-B Tablet

If you accidentally take more than the prescribed dose of Stat-B Tablet , seek immediate medical attention or contact a local poison control centre. Symptoms of an overdose may include severe nausea, vomiting, severe headache, confusion, or stomach pain.

Diet & Lifestyle Advise

Eat iron-rich foods: Incorporate spinach, red meat, beans, and fortified cereals into your diet to help rebuild iron levels lost during heavy bleeding.

  • Stay hydrated: Drink plenty of water to maintain blood volume and reduce the fatigue associated with heavy periods.
  • Apply gentle heat: Use a warm compress or heating pad on your lower back or abdomen to help soothe muscle cramping.
  • Limit caffeine and alcohol: Reducing these substances can help prevent dehydration and minimize stomach irritation while taking this medication.
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Have a query?

How Soon It Starts Working

  • The time required for Stat-B Tablet to start to work: The time required for Stat-B Tablet to show its action is unknown.
  • The time for which the effects of Stat-B Tablet last: The duration of action for Stat-B Tablet is unknown.

What if you forget to take Stat-B Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Take the medicine with food: Always take Stat-B Tablet with a meal or snack to help reduce stomach irritation and lower the risk of stomach ulcers.
  • Use only for the prescribed duration: Do not take Stat-B Tablet for longer or more frequently than recommended by your doctor.
  • Monitor for vision changes: Stop taking the medicine and seek medical advice immediately if you notice any unusual changes in your vision, including blurred vision or changes in color perception.
  • Avoid taking other pain relievers without medical advice: Do not use other NSAID pain medicines, such as ibuprofen or naproxen, while taking Stat-B Tablet unless specifically approved by your doctor, as this may increase the risk of side effects.
  • Watch for signs of stomach bleeding: Contact your healthcare provider immediately if you notice dark, black, tarry, or sticky stools, as this may indicate gastrointestinal bleeding.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Birth control pills and other estrogen-containing medicines: Taking these alongside Stat-B Tablet may increase the risk of developing blood clots.
  • Blood thinners (e.g., warfarin, heparin): Combining these with Stat-B Tablet may increase the risk of bleeding and may affect the effectiveness of either treatment.
  • Other nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., aspirin, ibuprofen): Taking these medicines alongside Stat-B Tablet may increase the risk of stomach irritation, ulcers, and bleeding
Mefenamic acidKetorolac
Critical
Mefenamic acidMeloxicam
Critical

Drug-Drug Interactions

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Mefenamic acidKetorolac
Critical
How does the drug interact with Stat-B Tablet:
Coadministration of Stat-B Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Stat-B Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidMeloxicam
Critical
How does the drug interact with Stat-B Tablet:
Co-administration of Stat-B Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Stat-B Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidApixaban
Severe
How does the drug interact with Stat-B Tablet:
Stat-B Tablet and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Stat-B Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without first consulting your doctor, never stop taking any medications.
Mefenamic acidMethotrexate
Severe
How does the drug interact with Stat-B Tablet:
Coadministration of Stat-B Tablet with Methotrexate may increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between Stat-B Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Mefenamic acidWarfarin
Severe
How does the drug interact with Stat-B Tablet:
Coadministration of Stat-B Tablet with Warfarin can increase the risk of bleeding.

How to manage the interaction:
Taking Stat-B Tablet with Warfarin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Mefenamic acidLithium
Severe
How does the drug interact with Stat-B Tablet:
Co-administration of Stat-B Tablet with Lithium can increase Lithium levels in the body.

How to manage the interaction:
Taking Stat-B Tablet with Lithium together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst, and/or increased urination, contact a doctor. Do not stop using any medications without talking to a doctor.
Mefenamic acidDasatinib
Severe
How does the drug interact with Stat-B Tablet:
Co-administration of Stat-B Tablet with Dasatinib can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Stat-B Tablet with Dasatinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, red or black tarry stools, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidPiroxicam
Severe
How does the drug interact with Stat-B Tablet:
Coadministration of Stat-B Tablet with Piroxicam can increase the risk side effects such as inflammation(swelling with redness and pain), bleeding, ulceration, and perforation leading to serious blood loss.

How to manage the interaction:
Taking Stat-B Tablet with Piroxicam together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidIndometacin
Severe
How does the drug interact with Stat-B Tablet:
The combined use of Indometacin and Stat-B Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indometacin with Stat-B Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Mefenamic acidDeferasirox
Severe
How does the drug interact with Stat-B Tablet:
Coadministration of Stat-B Tablet with Deferasirox can increase the risk or severity of gastric bleeding.

How to manage the interaction:
Taking Stat-B Tablet with Deferasirox together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid consuming alcohol while taking Stat-B Tablet , as it can increase the risk of stomach irritation, ulcers, and bleeding.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIFIBRINOLYTIC AGENTS]

FAQs

Stat-B Tablet is used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, it is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache.
Stat-B Tablet contains Tranexamic acid and Mefenamic acid. Tranexamic acid helps the body's natural blood clot process by preventing the breakdown of fibrin, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.
Diarrhea might be a side-effect of Stat-B Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhea. Consult your doctor if you experience severe diarrhea or if you find blood in stools.
Stat-B Tablet should not be taken for longer durations unless prescribed by the doctor. Stat-B Tablet is usually prescribed for a few days at the time of heavy bleeding and cramps.
Stat-B Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Stat-B Tablet only as prescribed and do not overdose.
Consult your doctor before taking contraceptive pills along with Stat-B Tablet . When taken together, there is an increased risk of deep vein thrombosis (blood clot in the deep vein, usually in the legs).
Stat-B Tablet contains mefenamic acid, an NSAID which might increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke. Therefore, avoid taking Stat-B Tablet if you have heart-related problems unless prescribed by the doctor.
Stat-B Tablet typically starts to show its effects within 1-2 hours of taking it, and it helps to reduce heavy menstrual bleeding by improving blood clotting but does not stop bleeding. However, the exact duration for bleeding to stop can vary from one person to other.
Yes, Stat-B Tablet can cause acidity. If you experience heartburn and indigestion, it's advisable to take Stat-B Tablet with food to minimize discomfort. If the symptoms persist, please consult your doctor.
Yes, Stat-B Tablet is safe if you take as per the dose and duration prescribed by your doctor. However, it's important to be aware of potential side effects and contraindications. Always consult your doctor before starting any new medication to ensure it is safe for you, especially if you have pre-existing conditions or are taking other medications.
Always follow your doctor's instructions regarding dosage and duration. Usually it is prescribed for a short duration. Do not exceed the prescribed duration. As overuse can lead to side effects and other health issues.
Stat-B Tablet is a combination of two drugs, tranexamic acid (anti-fibrinolytic) and mefenamic acid (NSAID).
Yes, do not take Stat-B Tablet if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Do not take any other NSAIDs for pain relief along with Stat-B Tablet unless prescribed.
Store Stat-B Tablet at a temperature not exceeding 25°C. Protect it from light and moisture. Keep out of reach of children.
Yes, you can take Stat-B Tablet with food. It is often recommended to take it after a meal to avoid stomach upset or other gastrointestinal side effects.
Please consult your doctor if you are pregnant. Your doctor will prescribes Stat-B Tablet only if the benefits outweigh the risks.
The common side effects of Stat-B Tablet are nausea, vomiting, diarrhea, indigestion, heartburn, and headache. If any of these side effects persist or worsen, please consult your doctor.
You are recommended to consult your doctor before taking other medicines with Stat-B Tablet to avoid possible interactions.

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Reference

  1. National Health Service (NHS). Tranexamic Acid - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 015034S040Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Mefenamic Acid Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Mefenamic acid. 2005. [Accessed on 10 Apr. 2019]Check here
  5. Rivopharm UK Ltd. Electronic medicines Compendium (EMC)Tranexamic Acid 500 mg film-coated tablets. [Revised on June 2018] [Accessed on 24th May 2022]Check here
  6. CDSCO [Internet]. Cdscoonline.gov.in. 2021 [Accessed on 22 November 2021]Check here
  7. Clinical Reference Document. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

5-5-35/54/B1, Plot No:200, Prashanti Nagar, Kukatpally, Hyderabad-500 072.
Other Info - STA0584
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