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  3. Stimin 0.5 mg Injection 1 ml

Stimin 0.5 mg Injection 1 ml, Pack of 1 INJECTION
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Composition :

NEOSTIGMINE-0.5MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Stimin 0.5 mg Injection 1 ml

Stimin 0.5 mg Injection 1 ml belongs to a group of medicines called 'anticholinesterase agents/acetylcholinesterase inhibitors,' primarily used to treat myasthenia gravis and to reverse the effects of anaesthesia medicines used during surgery. Stimin 0.5 mg Injection 1 ml is also used to treat paralytic ileus (a rare form of constipation) and postoperative urinary retention.

Stimin 0.5 mg Injection 1 ml contains 'Neostigmine.' It increases levels of a neurotransmitter called acetylcholine by stopping the excess cholinesterase activity (an enzyme required to break down acetylcholine) involved in communication between nerve impulses and muscle movements. Neurotransmitters are chemical messengers that transmit the message from one nerve cell to another nerve cell, muscle cell, or gland cell. Thus Stimin 0.5 mg Injection 1 ml helps in proper muscle functioning and prevents muscle weakness.

Stimin 0.5 mg Injection 1 ml will be administered by a health care professional, do not self-administer. Your dose and duration will be based on the severity of your medical condition. In some cases, you may experience common side effects, such as nausea, vomiting, slow heartbeat, abdominal cramp, diarrhoea, increased saliva production, dizziness, headache, trouble sleeping, and dry mouth. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor before using this medicine if you have a history of liver, heart or kidney diseases, asthma, stomach ulcer, fits, Parkinson's disease, overactive thyroid, or vagotonia/irritability of the vagus nerve (connects to the abdomen from the brain) that causes excess bowel contractions. Let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before starting Stimin 0.5 mg Injection 1 ml. Avoid consuming alcohol during the course to prevent unwanted side effects. Stimin 0.5 mg Injection 1 ml can be given to children if prescribed by the doctor; the dose depends on the child's age and weight.

Uses of Stimin 0.5 mg Injection 1 ml

Treatment of Myasthenia gravis, paralytic ileus, and post-operative urinary retention

Directions for Use

• Your doctor will determine the dosage and frequency depending on your condition.• Stimin 0.5 mg Injection 1 ml will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

Stimin 0.5 mg Injection 1 ml belongs to the group of medicines called 'anticholinesterase agents/cholinesterase inhibitors and is used to treat myasthenia gravis (muscle weakness). Stimin 0.5 mg Injection 1 ml contains 'Neostigmine'. It stops the excessive activity of cholinesterase, helping the muscles work properly. Additionally, Stimin 0.5 mg Injection 1 ml is used to treat paralytic ileus (a rare form of constipation) and postoperative urinary retention. It reverses the effects of neuromuscular blocking agents/anaesthesia medicines used during surgery. Stimin 0.5 mg Injection 1 ml affects the chemicals in the body, which are involved in communication between nerve impulses and muscle movements. Thereby, Stimin 0.5 mg Injection 1 ml treats muscle-associated disorders by improving muscle strength.

How Stimin 0.5 mg Injection 1 ml Works

Stimin 0.5 mg Injection 1 ml contains 'Neostigmine.' It increases levels of a neurotransmitter called acetylcholine by stopping the excess cholinesterase activity (an enzyme required to break down acetylcholine) involved in communication between nerve impulses and muscle movements. Neurotransmitters are chemical messengers that transmit the message from one nerve cell to another nerve cell, muscle cell, or gland cell. Thus Stimin 0.5 mg Injection 1 ml helps in proper muscle functioning and prevents muscle weakness.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Stimin 0.5 mg Injection 1 ml

Since Stimin 0.5 mg Injection 1 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Stimin 0.5 mg Injection 1 ml may cause constipation, decreased sexual ability, difficult urination, dry mouth, enlarged pupils, and muscle weakness.

Drug Warnings

Let your doctor know if you use any other medicines or supplements before using Stimin 0.5 mg Injection 1 ml. Brief your medical history if you have any liver or kidney diseases, heart diseases (coronary artery disease, irregular heartbeat), asthma, stomach ulcer, fits, urination problems, Parkinson's disease, overactive thyroid, and vagotonia before starting Stimin 0.5 mg Injection 1 ml. Please consult your doctor if you are pregnant, planning to conceive or are a breastfeeding mother. Avoid consuming alcohol to get the maximum benefits of the medicine and prevent the disease's aggravation. Drive or operate machinery only when you are alert and focused during the course.

Drug-Drug Interactions

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NeostigmineTramadol
Severe

Drug-Drug Interactions

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NeostigmineTramadol
Severe
How does the drug interact with Stimin 0.5 mg Injection 1 ml:
Co-administration of tramadol with Stimin 0.5 mg Injection 1 ml can increase the effect of tramadol.

How to manage the interaction:
Taking Stimin 0.5 mg Injection 1 ml with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat warm meals rather than hot meals, as heat aggravates the disease.
  • Try sipping a cold drink while having hot or warm meals.
  • Avoid foods that require a lot of chewing, like tough meats.
  • Exercise regularly to keep your muscles strong
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.

Habit Forming

No

Therapeutic Class

MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS

Stimin 0.5 mg Injection 1 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consuming alcohol during the course with Stimin 0.5 mg Injection 1 ml to prevent any undesirable side effects.

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Pregnancy

Caution

There is limited information on how Stimin 0.5 mg Injection 1 ml affects pregnancy. If you are pregnant or planning to conceive, inform your doctor before taking Stimin 0.5 mg Injection 1 ml.

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Breast Feeding

Caution

It is not known if Neostigmine is excreted into breast milk. Please inform your doctor before taking Stimin 0.5 mg Injection 1 ml if you are a breastfeeding mother.

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Driving

Caution

Neostigmine may make you feel dizzy and affect your ability to drive. It is advised not to drive or operate machinery while being treated with Stimin 0.5 mg Injection 1 ml if you are not mentally alert and focused.

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Liver

Caution

Please inform your doctor before receiving Stimin 0.5 mg Injection 1 ml if you have liver problems.

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Kidney

Caution

Please inform your doctor before receiving Stimin 0.5 mg Injection 1 ml if you have kidney disease.

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Children

Caution

Stimin 0.5 mg Injection 1 ml is recommended in children below 12 years of age only when prescribed by the doctor. The dosage depends on the child's age, weight and condition.

Have a query?

FAQs

Stimin 0.5 mg Injection 1 ml is used to treat Myasthenia gravis, paralytic ileus, and post-operative urinary retention.

Stimin 0.5 mg Injection 1 ml works by stopping the excessive cholinesterase activity (an enzyme necessary for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Stimin 0.5 mg Injection 1 ml helps in proper muscle functioning and prevents muscle weakness.

Stimin 0.5 mg Injection 1 ml should be used with caution in the medical history of liver or kidney diseases, heart diseases (coronary artery disease, irregular heartbeat), peritonitis (inflammation of the membrane lining the abdominal wall and covering the abdominal organs), stomach ulcer, asthma, fits, urination problems, Parkinson's disease, overactive thyroid (hypothyroidism), and vagotonia. Please let your doctor know if you have any other medical problems before starting Stimin 0.5 mg Injection 1 ml.

Generally, women aged 20 to 40 and men aged 50 to 80 are affected by myasthenia gravis. High-risk factors for developing this disease include autoimmune diseases like rheumatoid arthritis and lupus, infections, surgical procedures, thyroid disease, and medications for malaria, heart arrhythmias and cancer.

Diabetes may trigger a stronger immune response due to an abnormal rise in blood sugar levels. This may further lead to the worsening of the myasthenia gravis.

Yes, Stimin 0.5 mg Injection 1 ml is used to treat myasthenia gravis. It helps in proper muscle functioning and prevents muscle weakness.

Stimin 0.5 mg Injection 1 ml should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Stimin 0.5 mg Injection 1 ml starts working within 10-20 minutes after administration. The duration of action lasts for up to 4 hours.

No, Stimin 0.5 mg Injection 1 ml is not a steroid. Stimin 0.5 mg Injection 1 ml contains Neostigmine, an anticholinesterase agent/acetylcholinesterase inhibitor.

Stimin 0.5 mg Injection 1 ml is not known to cause weight gain. Consult the doctor if you notice any changes in weight during treatment with Stimin 0.5 mg Injection 1 ml.

Yes, Stimin 0.5 mg Injection 1 ml is usually safe and well-tolerated medicine when used in the prescribed dose and duration.

The doctor will determine the dose of Stimin 0.5 mg Injection 1 ml based on your medical condition. Please consult the doctor if you get tired easily, as it could be due to the increased severity of myasthenia gravis.

Stimin 0.5 mg Injection 1 ml is indicated for the treatment of paralytic ileus (a rare form of constipation) only. It should not be used for constipation due to other causes. Consult the doctor if you have any concerns.

Since Stimin 0.5 mg Injection 1 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

No, Stimin 0.5 mg Injection 1 ml does not have any abuse potential. It is not a habit-forming medicine.

Stimin 0.5 mg Injection 1 ml should be used by people who are allergic to any of its components. It is also not recommended if you have an intestinal obstruction or cannot urinate, a condition where your bowel may no longer be functioning, peritonitis (an infection or inflammation of the outer layer of the stomach or intestines) or if you are taking certain muscle relaxants (Suxamethonium).

Stimin 0.5 mg Injection 1 ml may cause side effects such as nausea, vomiting, slow heartbeat, abdominal cramps, diarrhoea, dizziness, headache, trouble sleeping, and dry mouth. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - STI0080

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:23 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/203629s000lbl.pdf
  2. https://www.drugs.com/mtm/neostigmine.html
  3. https://www.medicines.org.uk/emc/product/6268/smpc

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