apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:RANOLAZINE-500MG
prescription
Prescription Medicine
info
Stozina 500 Tablet 10's
Stozina 500 Tablet 10's
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
Get Extra 18% Off with Coupons
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

RANOLAZINE-500MG

Manufacturer/Marketer :

Katzung Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Stozina 500 Tablet

Stozina 500 Tablet is a prescription oral medication primarily used to treat chronic chest pain, also known as angina. It is prescribed for long-term management to help reduce the frequency of chest pain episodes. This medication is not intended to treat sudden, acute attacks of angina.

To work effectively, Stozina 500 Tablet must be taken consistently every day, usually twice daily, as directed by your doctor. You can take this medication with or without food, but it is important to be consistent with whichever method you choose. Combining this treatment with heart-healthy lifestyle habits, such as eating a balanced diet and engaging in light, doctor-approved physical activity, can significantly improve your overall outcomes.

While taking this medicine, some patients may experience mild side effects like dizziness, headache, nausea, or constipation. If you experience serious symptoms such as an irregular heartbeat, severe lightheadedness, or shortness of breath, you should contact your doctor immediately.

Do not take this if you have moderate to severe liver damage, as your body will not be able to process the medicine safely. Before starting, tell your healthcare provider if you have kidney problems or a family history of heart rhythm issues.

Stozina 500 Tablet can interact with certain medications, grapefruit juice, and alcohol, which can increase the risk of side effects like dizziness or heart rhythm changes. Pregnant women, breastfeeding mothers, and elderly patients should consult their doctor before starting this medicine to ensure it is safe for their specific circumstances.

Uses of Stozina 500 Tablet

The following are the primary therapeutic uses of Stozina 500 Tablet :

  • Chronic Angina: Stozina 500 Tablet helps by preventing and reducing the frequency of ongoing chest pain in patients with coronary artery disease, allowing for improved daily functioning.

Key Benefits

When taken as prescribed, Stozina 500 Tablet offers several benefits for people managing chronic angina:

  • Reduces angina episodes: Helps decrease the frequency of chest pain attacks, improving day-to-day comfort.
  • Supports physical activity: Enables patients to perform routine activities with less angina-related discomfort.
  • Does not significantly lower heart rate: Suitable for patients who may not tolerate medications that slow the heart excessively.
  • Has minimal impact on blood pressure: Can be a useful option for individuals with low blood pressure or those sensitive to blood pressure-lowering effects.
  • Improves quality of life: Helps patients maintain a more active and independent lifestyle by providing better symptom control.
Side effects of Stozina 500 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can release the medication too quickly and increase the risk of side effects.
  • Take it at the same times every day to maintain a steady level of the medicine in your body.
  • You may take this medicine with or without food, but keep your routine consistent.

Always follow your doctor's exact instructions regarding how and when to take this medication.

How Stozina 500 Tablet Works

Stozina 500 Tablet works by targeting the electrical and chemical processes inside the heart muscle cells. During chronic chest pain, heart cells can experience an abnormal buildup of sodium. This excess sodium leads to an overload of calcium, which prevents the heart muscle from fully relaxing between beats. By selectively blocking these late sodium channels, Stozina 500 Tablet prevents calcium buildup. This allows the heart muscle to relax properly, improving blood flow and oxygen delivery to the heart without altering your normal resting heart rate or blood pressure.
bannner image

Alcohol

Safe if prescribed

Stozina 500 Tablet does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.

bannner image

Pregnancy

Unsafe

Stozina 500 Tablet should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Stozina 500 Tablet .

bannner image

Breast Feeding

Consult your doctor

Stozina 500 Tablet should not be used in nursing mothers. Please consult the doctor if you have any concerns regarding this.

bannner image

Driving

Safe if prescribed

Stozina 500 Tablet does not have any reported interaction; hence, in case you experience any difficulty, discuss with your doctor.

bannner image

Liver

Caution

Stozina 500 Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Stozina 500 Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

bannner image

Children

Unsafe

Stozina 500 Tablet is not recommended for children below the age of 18. The safety and effectiveness of Stozina 500 Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

bannner image

Heart

Consult your doctor

Please consult your physician if you have any heart-related problems before taking Stozina 500 Tablet .

bannner image

Geriatrics

Consult your doctor

Your doctor will recommend Stozina 500 Tablet if needed in the geriatric population. Please consult your doctor.

What if I have taken an overdose of Stozina 500 Tablet

Do not take more than the prescribed dose of Stozina 500 Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid Grapefruit: Do not drink grapefruit juice or eat grapefruit while taking this medicine, as it can dangerously increase the levels of the drug in your system.
  • Monitor Salt Intake: Adopt a low-sodium diet to help manage underlying coronary artery disease and reduce strain on your cardiovascular system.
  • Stay Hydrated: Drink adequate amounts of water to help prevent constipation, which is a common side effect of this medication.
  • Engage in Gentle Exercise: Participate in moderate, doctor-approved activities like walking to support heart health without overexerting yourself.

Have a query?

How Soon It Starts Working

The time required for Stozina 500 Tablet to start to work: The time required for Stozina 500 Tablet to show its action is not clinically established. The time for which the effects of Stozina 500 Tablet last: The effect of Stozina 500 Tablet lasts for 21 days.

What if you forget to take Stozina 500 Tablet

Take the missed dose as soon as you remember. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store Stozina 500 Tablet tablets at room temperature, ideally between 20°C to 25°C (68°F to 77°F). • Keep the medication in its original container to protect it from moisture and direct light.

Drug Warnings

  • Avoid driving initially: Do not drive or operate machinery until you know how Stozina 500 Tablet affects you, as it commonly causes dizziness.
  • Check other prescriptions: Always let your doctor know about all other medications, supplements, or herbal products you are taking to prevent dangerous interactions.
  • Do not stop suddenly: Keep taking this medication even if you feel well; stopping it abruptly can cause your chest pain to return.
  • Stand up slowly: To reduce the risk of dizziness or fainting, rise slowly from sitting or lying positions.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

The following medicines may interact with Stozina 500 Tablet and affect its safety or effectiveness:

  • Strong CYP3A inhibitors: These medicines can increase the level of Stozina 500 Tablet in your blood, raising the risk of side effects.
  • Strong CYP3A inducers: These drugs can reduce the effectiveness of Stozina 500 Tablet by lowering its concentration in the body.
  • Heart rhythm medications: Taking these with Stozina 500 Tablet may increase the risk of abnormal heart rhythms.
  • Tuberculosis medications: Certain TB treatments can alter how Stozina 500 Tablet is metabolised, affecting its effectiveness.
  • Anti-seizure medications: These medicines may interfere with the blood levels and action of Stozina 500 Tablet .


Drug-Food Interactions

Certain foods and beverages may affect how Stozina 500 Tablet works in your body:

  • Grapefruit and grapefruit juice: Avoid these completely, as they can increase the amount of Stozina 500 Tablet in your bloodstream to unsafe levels.
  • Alcohol: Limiting alcohol intake is advised, as it may worsen dizziness and other side effects.


Drug-Disease Interactions

Some existing medical conditions may affect whether Stozina 500 Tablet is suitable for you:

  • Severe liver disease (cirrhosis): Do not take Stozina 500 Tablet if you have severe liver impairment, as it may lead to harmful drug accumulation.
  • Moderate-to-severe kidney disease: Use with caution, as impaired kidney function may affect how the medicine is processed.
  • Long QT syndrome: If you have a personal or family history of this heart rhythm disorder, Stozina 500 Tablet may increase the risk of serious cardiac complications.
RanolazineMesoridazine
Critical
RanolazineRifabutin
Critical

Drug-Drug Interactions

Login/Sign Up

RanolazineMesoridazine
Critical
How does the drug interact with Stozina 500 Tablet:
Co-administration of Mesoridazine and Stozina 500 Tablet may significantly increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Phenylbutazone with Stozina 500 Tablet can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop taking any medications without consulting a doctor.
RanolazineRifabutin
Critical
How does the drug interact with Stozina 500 Tablet:
Taking Rifabutin and Stozina 500 Tablet may significantly reduce the blood levels of Stozina 500 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Rifabutin and Stozina 500 Tablet, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RanolazineCarbamazepine
Critical
How does the drug interact with Stozina 500 Tablet:
Taking Stozina 500 Tablet with carbamazepine may significantly reduce the blood levels of Stozina 500 Tablet, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Stozina 500 Tablet with Carbamazepine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
RanolazinePosaconazole
Critical
How does the drug interact with Stozina 500 Tablet:
When Posaconazole is taken with Stozina 500 Tablet, may significantly increase the blood levels and effects of Stozina 500 Tablet.

How to manage the interaction:
Although there is an interaction between posaconazole and Stozina 500 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
RanolazinePentobarbital
Critical
How does the drug interact with Stozina 500 Tablet:
When Stozina 500 Tablet is taken with Pentobarbital, may significantly reduce the blood levels of Stozina 500 Tablet, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Phenobarbital with Stozina 500 Tablet can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazineGrepafloxacin
Critical
How does the drug interact with Stozina 500 Tablet:
Co-administration of Grepafloxacin and Stozina 500 Tablet may significantly increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Grepafloxacin with Stozina 500 Tablet can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop taking any medications without consulting a doctor.
RanolazineGriseofulvin
Critical
How does the drug interact with Stozina 500 Tablet:
When Stozina 500 Tablet is taken with Griseofulvin, may significantly reduce the blood levels of Stozina 500 Tablet, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Griseofulvin with Stozina 500 Tablet is not recommended, they can be taken together if advised by a doctor. Do not stop taking any medications without consulting a doctor.
RanolazineNevirapine
Critical
How does the drug interact with Stozina 500 Tablet:
Co-administration of Nevirapine with Stozina 500 Tablet may significantly reduce the blood levels of Stozina 500 Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nevirapine with Stozina 500 Tablet is generally avoided as it can lead to an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazineCisapride
Critical
How does the drug interact with Stozina 500 Tablet:
Co-administration of Stozina 500 Tablet with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Stozina 500 Tablet with Ceritinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RanolazineVoriconazole
Critical
How does the drug interact with Stozina 500 Tablet:
Co-administration of Stozina 500 Tablet together with Voriconazole may significantly increase the blood levels and effects of Stozina 500 Tablet.

How to manage the interaction:
Taking Stozina 500 Tablet with Voriconazole together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, or fast or pounding heartbeats. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
RANOLAZINE-500MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

Login/Sign Up

RANOLAZINE-500MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grapefruit juice can increase the levels of Stozina 500 Tablet, and high blood levels of food can occasionally cause an irregular heart rhythm that may be serious. Grapefruit and grapefruit juice should be avoided while taking Stozina 500 Tablet if possible.

All Substitutes & Brand Comparisons

Customers Also Bought

Habit Forming

No

Therapeutic Class

[ANTIANGINALS]

FAQs

Stozina 500 Tablet is used alone or with other medicines to treat angina pectoris.

The active substance in Stozina 500 Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Stozina 500 Tablet is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

No, Stozina 500 Tablet does not stop acute attacks (sudden attacks) of angina, but Stozina 500 Tablet helps prevent a new attack.

No, alcohol should not be taken with Stozina 500 Tablet as it may lead to unwanted side effects and increase angina attacks.

Yes, smoking (tobacco) decreases the efficacy of Stozina 500 Tablet , especially when taken for angina (chest pain), so it should be avoided while taking Stozina 500 Tablet .

Yes, Stozina 500 Tablet can cause an upset stomach when taken empty stomach. So, to avoid it, Stozina 500 Tablet should be taken with a meal for best results.

Yes, Stozina 500 Tablet can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.

Some major side effects include a rapid, pounding, or irregular heartbeat, difficulty breathing, and fainting. If you encounter any of these symptoms, contact your doctor immediately.

Do not take more than the prescribed dose of Stozina 500 Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Stozina 500 Tablet may increase the blood levels and effects of metoprolol. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects.

Stozina 500 Tablet might raise metformin levels, increasing the risk of lactic acidosis. If you are prescribed ranolazine while taking metformin, discuss it with a healthcare physician. They may offer a lesser dose of metformin as a safer alternative.

You can take it if prescribed by the doctor. However, limit simvastatin to 20 mg once daily in individuals taking any dose of Stozina 500 Tablet .

No, you should never crush, chew, or split Stozina 500 Tablet tablets. They are designed as extended-release tablets to slowly release the medicine into your body over time. Breaking them can cause too much medication to be absorbed at once. Talk to your doctor if you have trouble swallowing tablets.

Dizziness is a common side effect, especially when starting the medication. Try to sit or lie down until the feeling passes, and rise slowly when standing up. If the dizziness is severe or does not improve, talk to your doctor.

Unlike many other chronic chest pain medications, Stozina 500 Tablet does not significantly lower your blood pressure or slow your heart rate. This makes it a useful option for patients who already have low blood pressure or a slow pulse. Talk to your doctor for more details.

No, you should avoid grapefruit and grapefruit juice entirely while taking Stozina 500 Tablet . Grapefruit blocks enzymes that break down the drug, which can lead to dangerously high levels of the medicine in your body. Talk to your doctor or pharmacist if you have questions about foods to avoid.

Stozina 500 Tablet starts working within a few days, but it may take several weeks of consistent use to notice a significant reduction in your chest pain episodes. Keep taking it daily even if you do not feel immediate relief. Talk to your doctor if your symptoms do not improve.

The safety of Stozina 500 Tablet during pregnancy and breastfeeding is not fully established. You should only use this medication if the potential benefit justifies the potential risk. Talk to your doctor to discuss safer alternatives.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Plot No 368,Raghavendra Colony Beeramguda,Patancheruvu,Hyderabad,Telangana-502032 India
Other Info - STO0366

Buy best Cardiology products by

whatsapp Floating Button
Buy Now
Add to Cart