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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Stpen I 40mg/150mg Capsule SR is used to treat acidity, GERD (gastro-oesophagal reflux disease), and peptic ulcers. It contains Pantoprazole and Itopride, which decrease the production of acid. Additionally, it works by accelerating gastric emptying and improving gastric sensitivity and tone. It also has anti-emetic action. Thus, it helps in preventing acid reflux, thereby providing relief from acidity. In some cases, you may experience certain common side effects such as headache, nausea, stomach pain, dizziness and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Stpen I 40mg/150mg Capsule SR

Stpen I 40mg/150mg Capsule SR is a combination medicine used to treat acidity, gastroesophageal reflux disease (GERD), and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.

Stpen I 40mg/150mg Capsule SR is a combination of two drugs: Pantoprazole and Itopride. Pantoprazole works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid. Itopride works by accelerating gastric emptying and improving gastric sensitivity and tension. It also has anti-emetic action. Together, Stpen I 40mg/150mg Capsule SR helps in preventing acid reflux, thereby providing relief from acidity.

You are advised to take Stpen I 40mg/150mg Capsule SR as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as headache, nausea, stomach pain, dizziness and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking Stpen I 40mg/150mg Capsule SR if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. On long-term treatment, Stpen I 40mg/150mg Capsule SR may cause osteoporosis and hypomagnesemia (low levels of magnesium). Consult your doctor if you are pregnant or breastfeeding. Stpen I 40mg/150mg Capsule SR may cause drowsiness, so drive only if you are alert. Stpen I 40mg/150mg Capsule SR should not be given to children as safety has not been established. Avoid consuming alcohol along with Stpen I 40mg/150mg Capsule SR as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Stpen I 40mg/150mg Capsule SR

Stpen I 40mg/150mg Capsule SR is used in the treatment of hyperacidity, gastro-oesophageal reflux disease (GERD), and peptic ulcer. The detailed uses of Stpen I 40mg/150mg Capsule SR are as follows:

  • Hyperacidity: Stpen I 40mg/150mg Capsule SR works by reducing excessive stomach acid production, providing relief from symptoms such as heartburn, indigestion, and stomach discomfort.
  • Gastro-oesophageal reflux disease (GERD): Stpen I 40mg/150mg Capsule SR helps manage acid reflux by lowering acid levels, thereby reducing regurgitation, irritation of the oesophagus, and difficulty swallowing.
  • Peptic ulcer: Stpen I 40mg/150mg Capsule SR promotes healing of stomach and intestinal ulcers by decreasing acid secretion and preventing further damage to the ulcerated tissues.

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Directions for Use

  • Take Stpen I 40mg/150mg Capsule SR 30-60 minutes before food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Swallow Stpen I 40mg/150mg Capsule SR as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Stpen I 40mg/150mg Capsule SR is a combination of two drugs: Pantoprazole (a proton pump inhibitor) and Itopride (a prokinetic agent). Together, they provide the following medicinal benefits:
  • Pantoprazole decreases excessive stomach acid production, preventing irritation and damage to the stomach and oesophagus.
  • Itopride enhances stomach contractions, speeds up gastric emptying, and reduces bloating, nausea, and early satiety.
  • The combined action of both medicines controls the backwards flow of stomach contents, providing relief from heartburn and indigestion.
  • Reduced acid levels and improved stomach function help in the healing of peptic ulcers and prevent their recurrence.
  • The dual mechanism offers comprehensive relief from symptoms of acid-peptic disorders, including gastro-oesophageal reflux disease (GERD).

How Stpen I 40mg/150mg Capsule SR Works

Stpen I 40mg/150mg Capsule SR is a combination of two drugs: Pantoprazole and Itopride. Pantoprazole works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid. Itopride works by accelerating gastric emptying and improving gastric sensitivity and tension. It also has anti-emetic action. Together, Stpen I 40mg/150mg Capsule SR helps in preventing acid reflux, thereby providing relief from acidity.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Stpen I 40mg/150mg Capsule SR

Do not take more than the prescribed dose of Stpen I 40mg/150mg Capsule SR as it may cause an overdose. The symptoms of overdose include fever, back pain, slow/irregular heartbeat, rash, pain while peeing or blood in urine (signs of kidney problems) or stomach pain that worsens (sign of an inflammed liver or pancreas). If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not use Stpen I 40mg/150mg Capsule SR if you are allergic to Pantoprazole, Itopride, or any ingredient in the medicine. Seek immediate medical help if you experience symptoms of an allergic reaction such as rash, swelling, or difficulty breathing.
  • Inform your doctor about any history of gastrointestinal bleeding, stomach or intestinal perforation, bowel obstruction, movement disorders (such as Parkinson's disease), liver or kidney problems, autoimmune conditions (such as lupus), or electrolyte imbalances. Also, provide a complete list of all medications you are taking, as Stpen I 40mg/150mg Capsule SR may interact with certain drugs or require dose adjustments.
  • Long-term use of Pantoprazole (typically beyond 3–12 months) may cause low magnesium levels, leading to tremors, muscle cramps, seizures, or abnormal heart rhythms. Periodic magnesium level monitoring is advised.
  • Prolonged use of proton pump inhibitors like Pantoprazole (≥1 year) may increase the risk of bone fractures, particularly in the hip, wrist, or spine. Use the lowest effective dose for the shortest required duration.
  • Extended use may reduce absorption of vitamin B₁₂, calcium, and iron, and may increase the risk of gastrointestinal infections (Clostridioides difficile), pneumonia, or formation of stomach polyps.
  • Report any unusual symptoms such as joint pain, persistent rash, fever, or dark-colored urine, as these may indicate rare but serious side effects such as kidney inflammation or lupus-like reactions.
  • Consult your doctor before using Stpen I 40mg/150mg Capsule SR if you are pregnant or breastfeeding, as safety data are limited. Use in children has not been established and is generally not recommended.

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Stpen I 40mg/150mg Capsule SR:
Co-administration of Rilpivirine is taken with Stpen I 40mg/150mg Capsule SR, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Stpen I 40mg/150mg Capsule SR with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Stpen I 40mg/150mg Capsule SR:
Co-administration of Methotrexate with Stpen I 40mg/150mg Capsule SR can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Stpen I 40mg/150mg Capsule SR and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Stpen I 40mg/150mg Capsule SR:
Co-administration of Stpen I 40mg/150mg Capsule SR reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Stpen I 40mg/150mg Capsule SR with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Stpen I 40mg/150mg Capsule SR:
Taking Dasatinib with Stpen I 40mg/150mg Capsule SR may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Stpen I 40mg/150mg Capsule SR with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
PantoprazoleNelfinavir
Severe
How does the drug interact with Stpen I 40mg/150mg Capsule SR:
Taking Nelfinavir with Stpen I 40mg/150mg Capsule SR may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Stpen I 40mg/150mg Capsule SR with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Stpen I 40mg/150mg Capsule SR:
Taking Erlotinib with Stpen I 40mg/150mg Capsule SR may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Stpen I 40mg/150mg Capsule SR with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Stpen I 40mg/150mg Capsule SR:
Taking Gefitinib with Stpen I 40mg/150mg Capsule SR reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Stpen I 40mg/150mg Capsule SR with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Stpen I 40mg/150mg Capsule SR to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Stpen I 40mg/150mg Capsule SR:
Taking Stpen I 40mg/150mg Capsule SR can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Stpen I 40mg/150mg Capsule SR with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Stpen I 40mg/150mg Capsule SR:
Taking Stpen I 40mg/150mg Capsule SR with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Stpen I 40mg/150mg Capsule SR and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight through regular exercise.
  • Avoid lying down after eating.
  • Avoid tight-fitting clothes.
  • Maintain a healthy weight through regular exercise.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes, every hour, by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Stpen I 40mg/150mg Capsule SR. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

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Pregnancy

Caution

Consult your doctor before taking Stpen I 40mg/150mg Capsule SR if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Stpen I 40mg/150mg Capsule SR; your doctor will decide whether Stpen I 40mg/150mg Capsule SR can be taken by breastfeeding mothers or not.

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Driving

Caution

Stpen I 40mg/150mg Capsule SR may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Stpen I 40mg/150mg Capsule SR if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Stpen I 40mg/150mg Capsule SR if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Stpen I 40mg/150mg Capsule SR should not be given to children as safety and effectiveness were not established.

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Heart

Exercise caution while taking Stpen I 40mg/150mg Capsule SR, if you have any heart problems. Please consult your physician.

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Geriatrics

Caution

Exercise caution while giving Stpen I 40mg/150mg Capsule SR in elderly patients. Please consult your physician.

FAQs

Stpen I 40mg/150mg Capsule SR is used to treat acidity, GERD (gastro-oesophagal reflux disease), and peptic ulcers.

Stpen I 40mg/150mg Capsule SR is a combination of two drugs, namely: Pantoprazole and Itopride. Pantoprazole works by blocking the action of an enzyme called gastric proton pump, responsible for the production of acid. Itopride works by accelerating gastric emptying and improves gastric sensitivity and tension. Together, Stpen I 40mg/150mg Capsule SR helps in preventing acid reflux, thereby provides relief from acidity.

Talk to your doctor if you do not feel better even after taking Stpen I 40mg/150mg Capsule SR for 14 days. Do not take Stpen I 40mg/150mg Capsule SR for longer durations unless prescribed by the doctor.

Diarrhoea might be a side-effect of Stpen I 40mg/150mg Capsule SR. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Country of origin

India
Other Info - ST53835

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